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The map label for this gene is mdtA [H]

Identifier: 29141248

GI number: 29141248

Start: 830448

End: 831689

Strand: Reverse

Name: mdtA [H]

Synonym: t0746

Alternate gene names: 29141248

Gene position: 831689-830448 (Counterclockwise)

Preceding gene: 29141249

Following gene: 29141247

Centisome position: 17.36

GC content: 57.73

Gene sequence:

>1242_bases
ATGAAAGGCAGTAATACTTTCCGCTGGGCAATAGCGATTGGGGTTGTAGTGGCCGCCGCCGCATTCTGGTTCTGGCATAG
CCGTAGCGAAAGCCCGACCGCCGCGCCGGGCGTCGCCGCGCAAGCGCAGCATACCGCCGCCGCAGGTCGCCGCGGTATGC
GCGACGGCCCTCTGGCGCCGGTACAGGCCGCGACCGCGACCACACAGGCTGTACCGCGCTATCTGAGCGGGCTGGGTACC
GTGACCGCAGCGAATACCGTTACGGTGCGTAGCCGCGTGGATGGTCAACTCATCGCCCTGCACTTTCAGGAAGGTCAGCA
GGTTAACGCAGGCGATCTGCTGGCGCAAATCGATCCCAGCCAGTTTAAGGTCGCCCTGGCGCAGGCTCAGGGACAGTTAG
CGAAAGATAACGCTACGTTGGCGAATGCGCGTCGTGATCTGGCGCGCTATCAGCAACTGGCCAAAACCAATCTGGTTTCC
CGTCAGGAACTGGATGCGCAACAGGCGCTGGTCAACGAAACCCAGGGAACCATTAAAGCGGATGAAGCCAATGTCGCCAG
CGCGCAGCTACAGCTCGACTGGAGTCGTATCACAGCCCCGGTCTCGGGACGCGTGGGTCTGAAACAGGTGGATGTCGGCA
ACCAGATTTCCAGCAGCGATACCGCAGGTATTGTCGTCATTACGCAAACGCACCCGATTGATCTCATTTTTACTCTGCCG
GAAAGCGATATCGCGACCGTGGTTCAGGCACAGAAAGCGGGGAAAACGCTGGTCGTAGAAGCCTGGGATCGAACTAACTC
GCACAAATTGAGCGAAGGCGTGTTGCTCAGTCTGGACAACCAGATTGATCCCACGACGGGAACGATCAAAATTAAAGCGC
GCTTTACCAATCAGGACGATACGCTGTTCCCCAATCAATTTGTGAACGCCCGGATGCTGGTCGATACCGAACAAAATGCC
GTTGTGGTGCCTGCCGCGGCGGTGCAAATGGGCAATGAGGGCCACTTTGTGTGGGTGCTGAACGACGAAAATAACGTCAG
CAAGAAGCGGGTAAAAATCGGTATTCAGGATAACCGAAACGTGGTGATCAGCGCAGGATTGTCGGCAGGCGATCGCGTCG
TTACCGATGGTATTGATCGGCTGACGGAAGGCGCAAAAGTCGAGGTCGTTGAGCCGCAAACCACCATGGCGGATGAAAAA
TCCCCTTCCCGCCATGAAGGTCAAAAAGGAGCGCGCGCCTGA

Upstream 100 bases:

>100_bases
GACCGTGTTCCATAATTCCTCCATTTTTCTCCCTTCCCTGCTGACTACAATAGAGGAAGCAACATTCCGCAAAACGTTTC
AGGATGAGAAACTTATACCG

Downstream 100 bases:

>100_bases
TGCAGGTATTACCTCCGGGCAGCACGGGCGGCCCTTCGCGTCTGTTTATTCTGCGCCCCGTGGCCACCACTCTGCTGATG
GCGGCGATTTTACTCGCCGG

Product: multidrug efflux system subunit MdtA

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MKGSNTFRWAIAIGVVVAAAAFWFWHSRSESPTAAPGVAAQAQHTAAAGRRGMRDGPLAPVQAATATTQAVPRYLSGLGT
VTAANTVTVRSRVDGQLIALHFQEGQQVNAGDLLAQIDPSQFKVALAQAQGQLAKDNATLANARRDLARYQQLAKTNLVS
RQELDAQQALVNETQGTIKADEANVASAQLQLDWSRITAPVSGRVGLKQVDVGNQISSSDTAGIVVITQTHPIDLIFTLP
ESDIATVVQAQKAGKTLVVEAWDRTNSHKLSEGVLLSLDNQIDPTTGTIKIKARFTNQDDTLFPNQFVNARMLVDTEQNA
VVVPAAAVQMGNEGHFVWVLNDENNVSKKRVKIGIQDNRNVVISAGLSAGDRVVTDGIDRLTEGAKVEVVEPQTTMADEK
SPSRHEGQKGARA

Sequences:

>Translated_413_residues
MKGSNTFRWAIAIGVVVAAAAFWFWHSRSESPTAAPGVAAQAQHTAAAGRRGMRDGPLAPVQAATATTQAVPRYLSGLGT
VTAANTVTVRSRVDGQLIALHFQEGQQVNAGDLLAQIDPSQFKVALAQAQGQLAKDNATLANARRDLARYQQLAKTNLVS
RQELDAQQALVNETQGTIKADEANVASAQLQLDWSRITAPVSGRVGLKQVDVGNQISSSDTAGIVVITQTHPIDLIFTLP
ESDIATVVQAQKAGKTLVVEAWDRTNSHKLSEGVLLSLDNQIDPTTGTIKIKARFTNQDDTLFPNQFVNARMLVDTEQNA
VVVPAAAVQMGNEGHFVWVLNDENNVSKKRVKIGIQDNRNVVISAGLSAGDRVVTDGIDRLTEGAKVEVVEPQTTMADEK
SPSRHEGQKGARA
>Mature_413_residues
MKGSNTFRWAIAIGVVVAAAAFWFWHSRSESPTAAPGVAAQAQHTAAAGRRGMRDGPLAPVQAATATTQAVPRYLSGLGT
VTAANTVTVRSRVDGQLIALHFQEGQQVNAGDLLAQIDPSQFKVALAQAQGQLAKDNATLANARRDLARYQQLAKTNLVS
RQELDAQQALVNETQGTIKADEANVASAQLQLDWSRITAPVSGRVGLKQVDVGNQISSSDTAGIVVITQTHPIDLIFTLP
ESDIATVVQAQKAGKTLVVEAWDRTNSHKLSEGVLLSLDNQIDPTTGTIKIKARFTNQDDTLFPNQFVNARMLVDTEQNA
VVVPAAAVQMGNEGHFVWVLNDENNVSKKRVKIGIQDNRNVVISAGLSAGDRVVTDGIDRLTEGAKVEVVEPQTTMADEK
SPSRHEGQKGARA

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=415, Percent_Identity=82.8915662650602, Blast_Score=669, Evalue=0.0,
Organism=Escherichia coli, GI1789929, Length=312, Percent_Identity=30.1282051282051, Blast_Score=141, Evalue=8e-35,
Organism=Escherichia coli, GI1789665, Length=317, Percent_Identity=30.2839116719243, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1786668, Length=321, Percent_Identity=30.2180685358255, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI87081951, Length=248, Percent_Identity=27.4193548387097, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081796, Length=315, Percent_Identity=26.031746031746, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 44128; Mature: 44128

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGSNTFRWAIAIGVVVAAAAFWFWHSRSESPTAAPGVAAQAQHTAAAGRRGMRDGPLAP
CCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
VQAATATTQAVPRYLSGLGTVTAANTVTVRSRVDGQLIALHFQEGQQVNAGDLLAQIDPS
CHHHHHHHHHHHHHHHCCCCEEECCEEEEEECCCCEEEEEEECCCCCCCCCCEEEEECHH
QFKVALAQAQGQLAKDNATLANARRDLARYQQLAKTNLVSRQELDAQQALVNETQGTIKA
HHHEEEEHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEE
DEANVASAQLQLDWSRITAPVSGRVGLKQVDVGNQISSSDTAGIVVITQTHPIDLIFTLP
CCCCEEEEEEEEEHHHEECCCCCCCCCEEECCCCCCCCCCCCEEEEEEECCCEEEEEECC
ESDIATVVQAQKAGKTLVVEAWDRTNSHKLSEGVLLSLDNQIDPTTGTIKIKARFTNQDD
CCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEEECCCCC
TLFPNQFVNARMLVDTEQNAVVVPAAAVQMGNEGHFVWVLNDENNVSKKRVKIGIQDNRN
CCCCCHHCCEEEEEECCCCEEEEEHHHEEECCCCCEEEEECCCCCCCEEEEEEEEECCCE
VVISAGLSAGDRVVTDGIDRLTEGAKVEVVEPQTTMADEKSPSRHEGQKGARA
EEEECCCCCCCEEHHHHHHHHCCCCEEEEECCCHHCCCCCCCCHHCCCCCCCC
>Mature Secondary Structure
MKGSNTFRWAIAIGVVVAAAAFWFWHSRSESPTAAPGVAAQAQHTAAAGRRGMRDGPLAP
CCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
VQAATATTQAVPRYLSGLGTVTAANTVTVRSRVDGQLIALHFQEGQQVNAGDLLAQIDPS
CHHHHHHHHHHHHHHHCCCCEEECCEEEEEECCCCEEEEEEECCCCCCCCCCEEEEECHH
QFKVALAQAQGQLAKDNATLANARRDLARYQQLAKTNLVSRQELDAQQALVNETQGTIKA
HHHEEEEHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEE
DEANVASAQLQLDWSRITAPVSGRVGLKQVDVGNQISSSDTAGIVVITQTHPIDLIFTLP
CCCCEEEEEEEEEHHHEECCCCCCCCCEEECCCCCCCCCCCCEEEEEEECCCEEEEEECC
ESDIATVVQAQKAGKTLVVEAWDRTNSHKLSEGVLLSLDNQIDPTTGTIKIKARFTNQDD
CCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEEECCCCC
TLFPNQFVNARMLVDTEQNAVVVPAAAVQMGNEGHFVWVLNDENNVSKKRVKIGIQDNRN
CCCCCHHCCEEEEEECCCCEEEEEHHHEEECCCCCEEEEECCCCCCCEEEEEEEEECCCE
VVISAGLSAGDRVVTDGIDRLTEGAKVEVVEPQTTMADEKSPSRHEGQKGARA
EEEECCCCCCCEEHHHHHHHHCCCCEEEEECCCHHCCCCCCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA