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The map label for this gene is glpA [H]

Identifier: 29141095

GI number: 29141095

Start: 655228

End: 656856

Strand: Reverse

Name: glpA [H]

Synonym: t0580

Alternate gene names: 29141095

Gene position: 656856-655228 (Counterclockwise)

Preceding gene: 29141098

Following gene: 29141094

Centisome position: 13.71

GC content: 58.75

Gene sequence:

>1629_bases
ATGAAAACTCGCGACTCGCAAGCAAGTGACGTGATTATCATTGGCGGTGGAGCAACAGGCGCAGGGATCGCCCGCGACTG
CGCGCTGCGCGGTTTACGTGTCATTCTGGTGGAGCGGCATGATATAGCGACCGGCGCGACCGGGCGTAACCACGGGCTGC
TGCACAGCGGCGCTCGTTATGCGGTTACCGACGCGGAATCCGCGCGCGAGTGCATTAGTGAAAACCAGATTTTAAAACGG
ATCGCCCGCCATTGCGTCGAACCGACGGATGGTCTGTTTATTACGTTGCCGGAAGATGGTCTTGCGTTTCAGGCCACCTT
TATTCGCGCCTGTGAAGCGGCAGGCATTCGCGCTGAAGCCATCGATCCGCAGCAGGCTCGCATCATCGAACCTTCCGTTA
ACCCTGCGCTCATCGGTGCGGTAAAAGTGCCGGATGGCACCGTAGACCCTTTCCGCCTGACCGCCGCCAATATGCTGGAT
GCCAGAGAACATGGCGCAATCGTGTTAACGGCGCATGAAGTGACCGGGCTCATTCGTGAAGGCGCAACGGTCTGCGGCGT
CCATGTGCGTAACCATCTCACTGGCGAAACCCAGACGCTTCACGCGCCGGTGGTGGTCAATGCGGCTGGTATCTGGGGGC
AACGGATCGCCGAATACGCCGACCTGAGTATTCGCATGTTCCCGGCGAAAGGCTCGCTGTTGATCATGGACCATCGGATC
AACCAGCATGTCATTAACCGCTGCCGGAAACCATCGGATGCCGACATTCTGGTACCTGGCGATACGATTTCACTGATCGG
CACCACCTCTACCCATATTGATTACAATGAGATAGACAGCAACCGCGTCACCGCAGATGAAGTCGATATCCTGCTGCGTG
AAGGGGAAAAACTGGCCCCTGTCATGGCGAAGACACGTATTCTGCGCGCGTATTCCGGCGTCCGCCCGCTGGTGGCCAGC
GATGACGATCCCAGCGGTCGTAACGTCAGCCGCGGTATTGTGTTGTTCGACCACGCCGAACGCGACGGGCTTGATGGCTT
CATTACCATTACCGGCGGGAAGCTAATGACTTATCGCCTGATGGCGGAATGGGCGACCGACGCCGTGTGCCGCAAGTTGG
GCAATACTCGCCCCTGCATCACGGCGGATACGCCGTTGCCTGGCTCAAAAGAGTCTACGGAACATACGCTGAAACGCATT
ATCTCGCTTCCCGCGCCGCTACGCGGATCGGCGGTTTATCGGCATGGCGATCGCACGCCGGGGTGGCTGAGTGAAGGCCG
CCAACACCGTAGCCTGGTCTGTGAATGCGAGGCCGTCACGGCGGGGGAAGTGCAGTATGCCGTCGAAAACTTAACCGTGA
ATAGCCTGCTGGATCTGCGCCGTCGCACCCGCGTAGGGATGGGCACTTGCCAGGGCGAACTGTGCGCCTGCCGCGCGGCC
GGGCTATTGCAGCGTTTTAATGTGACGACCGCGGCGCAATCTATTACGCAACTCTCTGAATTTCTGAATGAGCGCTGGAA
AGGCGTACAACCTGTCGCCTGGGGAGACGCGCTGCGCGAAAGCGAATTCACGCGCTGGGTTTATCAGGGATTATGCGGTC
TGGAGAAGGAGCACCAGGATGAAATTTGA

Upstream 100 bases:

>100_bases
GTTACAGTTTTATGACTAATGTTCAGAAAGGCGCGCGAAATCAAACATTCCATATGATTTGTATGGCTAAATGATAAAAA
ACGAACTGTAAGGAAAAACA

Downstream 100 bases:

>100_bases
TACGGTTATTATGGGCGGCGGTCTCGCCGGTTTGCTATGCGGACTGCAACTCCAGCAGCATGGATTACGCTGCGCCATCG
TCACCCGCGGACAAAGCGCG

Product: sn-glycerol-3-phosphate dehydrogenase subunit A

Products: NA

Alternate protein names: G-3-P dehydrogenase [H]

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MKTRDSQASDVIIIGGGATGAGIARDCALRGLRVILVERHDIATGATGRNHGLLHSGARYAVTDAESARECISENQILKR
IARHCVEPTDGLFITLPEDGLAFQATFIRACEAAGIRAEAIDPQQARIIEPSVNPALIGAVKVPDGTVDPFRLTAANMLD
AREHGAIVLTAHEVTGLIREGATVCGVHVRNHLTGETQTLHAPVVVNAAGIWGQRIAEYADLSIRMFPAKGSLLIMDHRI
NQHVINRCRKPSDADILVPGDTISLIGTTSTHIDYNEIDSNRVTADEVDILLREGEKLAPVMAKTRILRAYSGVRPLVAS
DDDPSGRNVSRGIVLFDHAERDGLDGFITITGGKLMTYRLMAEWATDAVCRKLGNTRPCITADTPLPGSKESTEHTLKRI
ISLPAPLRGSAVYRHGDRTPGWLSEGRQHRSLVCECEAVTAGEVQYAVENLTVNSLLDLRRRTRVGMGTCQGELCACRAA
GLLQRFNVTTAAQSITQLSEFLNERWKGVQPVAWGDALRESEFTRWVYQGLCGLEKEHQDEI

Sequences:

>Translated_542_residues
MKTRDSQASDVIIIGGGATGAGIARDCALRGLRVILVERHDIATGATGRNHGLLHSGARYAVTDAESARECISENQILKR
IARHCVEPTDGLFITLPEDGLAFQATFIRACEAAGIRAEAIDPQQARIIEPSVNPALIGAVKVPDGTVDPFRLTAANMLD
AREHGAIVLTAHEVTGLIREGATVCGVHVRNHLTGETQTLHAPVVVNAAGIWGQRIAEYADLSIRMFPAKGSLLIMDHRI
NQHVINRCRKPSDADILVPGDTISLIGTTSTHIDYNEIDSNRVTADEVDILLREGEKLAPVMAKTRILRAYSGVRPLVAS
DDDPSGRNVSRGIVLFDHAERDGLDGFITITGGKLMTYRLMAEWATDAVCRKLGNTRPCITADTPLPGSKESTEHTLKRI
ISLPAPLRGSAVYRHGDRTPGWLSEGRQHRSLVCECEAVTAGEVQYAVENLTVNSLLDLRRRTRVGMGTCQGELCACRAA
GLLQRFNVTTAAQSITQLSEFLNERWKGVQPVAWGDALRESEFTRWVYQGLCGLEKEHQDEI
>Mature_542_residues
MKTRDSQASDVIIIGGGATGAGIARDCALRGLRVILVERHDIATGATGRNHGLLHSGARYAVTDAESARECISENQILKR
IARHCVEPTDGLFITLPEDGLAFQATFIRACEAAGIRAEAIDPQQARIIEPSVNPALIGAVKVPDGTVDPFRLTAANMLD
AREHGAIVLTAHEVTGLIREGATVCGVHVRNHLTGETQTLHAPVVVNAAGIWGQRIAEYADLSIRMFPAKGSLLIMDHRI
NQHVINRCRKPSDADILVPGDTISLIGTTSTHIDYNEIDSNRVTADEVDILLREGEKLAPVMAKTRILRAYSGVRPLVAS
DDDPSGRNVSRGIVLFDHAERDGLDGFITITGGKLMTYRLMAEWATDAVCRKLGNTRPCITADTPLPGSKESTEHTLKRI
ISLPAPLRGSAVYRHGDRTPGWLSEGRQHRSLVCECEAVTAGEVQYAVENLTVNSLLDLRRRTRVGMGTCQGELCACRAA
GLLQRFNVTTAAQSITQLSEFLNERWKGVQPVAWGDALRESEFTRWVYQGLCGLEKEHQDEI

Specific function: Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor [H]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=Loosely bound to the cytoplasmic membrane often occurring in vesicles associated with fumarate reductase (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=516, Percent_Identity=25.3875968992248, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI285002231, Length=516, Percent_Identity=25.3875968992248, Blast_Score=115, Evalue=1e-25,
Organism=Escherichia coli, GI1788574, Length=542, Percent_Identity=92.619926199262, Blast_Score=1004, Evalue=0.0,
Organism=Escherichia coli, GI2367226, Length=468, Percent_Identity=26.2820512820513, Blast_Score=85, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17509253, Length=411, Percent_Identity=30.1703163017032, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI115534726, Length=420, Percent_Identity=27.8571428571429, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI161077125, Length=398, Percent_Identity=29.8994974874372, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24653942, Length=398, Percent_Identity=29.8994974874372, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24653944, Length=398, Percent_Identity=29.8994974874372, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI20130025, Length=398, Percent_Identity=29.8994974874372, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI19921278, Length=505, Percent_Identity=24.7524752475248, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI20130091, Length=238, Percent_Identity=27.7310924369748, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007419
- InterPro:   IPR006076
- InterPro:   IPR017752
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO; PF04324 Fer2_BFD [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 58970; Mature: 58970

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTRDSQASDVIIIGGGATGAGIARDCALRGLRVILVERHDIATGATGRNHGLLHSGARY
CCCCCCCCCCEEEECCCCCCCCHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCEECCCEE
AVTDAESARECISENQILKRIARHCVEPTDGLFITLPEDGLAFQATFIRACEAAGIRAEA
EEECHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEHHHHHHHHHHCCCEEEC
IDPQQARIIEPSVNPALIGAVKVPDGTVDPFRLTAANMLDAREHGAIVLTAHEVTGLIRE
CCCCCCEEECCCCCCEEEEEEECCCCCCCCCEEHHHHHHHHHHCCEEEEEHHHHHHHHHC
GATVCGVHVRNHLTGETQTLHAPVVVNAAGIWGQRIAEYADLSIRMFPAKGSLLIMDHRI
CCEEEEEEHHHCCCCCCEEEECCEEEEECCHHHHHHHHHHCCEEEEECCCCCEEEEECCC
NQHVINRCRKPSDADILVPGDTISLIGTTSTHIDYNEIDSNRVTADEVDILLREGEKLAP
CHHHHHHCCCCCCCEEEECCCEEEEEECCCCCCCHHHCCCCCCCHHHHHHHHHCCCHHHH
VMAKTRILRAYSGVRPLVASDDDPSGRNVSRGIVLFDHAERDGLDGFITITGGKLMTYRL
HHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCEEEHHH
MAEWATDAVCRKLGNTRPCITADTPLPGSKESTEHTLKRIISLPAPLRGSAVYRHGDRTP
HHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCC
GWLSEGRQHRSLVCECEAVTAGEVQYAVENLTVNSLLDLRRRTRVGMGTCQGELCACRAA
CHHHCCHHHCCEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHH
GLLQRFNVTTAAQSITQLSEFLNERWKGVQPVAWGDALRESEFTRWVYQGLCGLEKEHQD
HHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCC
EI
CC
>Mature Secondary Structure
MKTRDSQASDVIIIGGGATGAGIARDCALRGLRVILVERHDIATGATGRNHGLLHSGARY
CCCCCCCCCCEEEECCCCCCCCHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCEECCCEE
AVTDAESARECISENQILKRIARHCVEPTDGLFITLPEDGLAFQATFIRACEAAGIRAEA
EEECHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEHHHHHHHHHHCCCEEEC
IDPQQARIIEPSVNPALIGAVKVPDGTVDPFRLTAANMLDAREHGAIVLTAHEVTGLIRE
CCCCCCEEECCCCCCEEEEEEECCCCCCCCCEEHHHHHHHHHHCCEEEEEHHHHHHHHHC
GATVCGVHVRNHLTGETQTLHAPVVVNAAGIWGQRIAEYADLSIRMFPAKGSLLIMDHRI
CCEEEEEEHHHCCCCCCEEEECCEEEEECCHHHHHHHHHHCCEEEEECCCCCEEEEECCC
NQHVINRCRKPSDADILVPGDTISLIGTTSTHIDYNEIDSNRVTADEVDILLREGEKLAP
CHHHHHHCCCCCCCEEEECCCEEEEEECCCCCCCHHHCCCCCCCHHHHHHHHHCCCHHHH
VMAKTRILRAYSGVRPLVASDDDPSGRNVSRGIVLFDHAERDGLDGFITITGGKLMTYRL
HHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCEEEHHH
MAEWATDAVCRKLGNTRPCITADTPLPGSKESTEHTLKRIISLPAPLRGSAVYRHGDRTP
HHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCC
GWLSEGRQHRSLVCECEAVTAGEVQYAVENLTVNSLLDLRRRTRVGMGTCQGELCACRAA
CHHHCCHHHCCEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHH
GLLQRFNVTTAAQSITQLSEFLNERWKGVQPVAWGDALRESEFTRWVYQGLCGLEKEHQD
HHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCC
EI
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]