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The map label for this gene is pmrF [H]

Identifier: 29141080

GI number: 29141080

Start: 641025

End: 642008

Strand: Reverse

Name: pmrF [H]

Synonym: t0565

Alternate gene names: 29141080

Gene position: 642008-641025 (Counterclockwise)

Preceding gene: 161486811

Following gene: 29141079

Centisome position: 13.4

GC content: 52.95

Gene sequence:

>984_bases
ATGTTTGACGCCGCCCCCATAAAAAAAGTCTCGGTGGTTATTCCTGTCTATAACGAACAGGAAAGCCTGCCGGAATTGAT
AAGACGCACCACCACCGCCTGCGAGAGTCTGGGCAAAGCGTGGGAGATTTTATTGATAGATGATGGTAGCAGCGATAGCT
CGGCGGAGCTGATGGTTAAGGCGTCCCAGGAGGCCGATAGCCATATCATCTCTATTTTACTCAACCGTAACTACGGTCAA
CATGCAGCGATTATGGCGGGGTTTAGCCATGTAAGCGGCGATCTCATCATTACGCTGGATGCCGATCTGCAAAACCCGCC
GGAAGAGATCCCGCGCCTGGTGGCGAAAGCCGATGAAGGGTTCGATGTGGTAGGCACCGTGCGACAGAACCGACAGGACA
GCCTGTTTCGCAAATCGGCGTCAAAAATCATTAATCTGCTGATCCAGCGCACAACGGGCAAAGCGATGGGCGATTACGGC
TGCATGTTACGCGCCTATCGCCGCCCTATTATCGATACCATGTTGCGCTGCCATGAACGCAGCACCTTTATCCCTATTCT
GGCCAACATTTTCGCTCGTCGGGCTACCGAAATCCCGGTGCATCACGCTGAACGTGAATTTGGCGACTCTAAATACAGTT
TTATGCGTCTCATTAACCTGATGTATGACCTGGTGACCTGCCTGACGACGACGCCTCTGCGCCTGTTGAGTCTGCTGGGC
AGTGTTATCGCCATCGGCGGGTTTAGCCTGTCGGTATTGCTTATTGTACTTCGCCTGGCACTGGGACCGCAGTGGGCGGC
GGAAGGCGTATTTATGCTCTTTGCCGTTCTGTTTACCTTCATCGGCGCGCAATTCATCGGTATGGGACTGCTGGGCGAAT
ACATCGGTCGCATTTATAACGATGTCCGCGCCCGCCCCCGCTATTTTGTTCAACAAGTTATCTACCCGGAAAGCACGTCG
TTTACTGAGGAAAGTCACCAATGA

Upstream 100 bases:

>100_bases
ACAGCGAGCGGATCTGCTCACTGCCGCTCTTCCCGGACATGACCGAGAGTGACTTTGATCGGGTCATTACCGCCCTTCAT
CAGATAGCAGGACAATAAGC

Downstream 100 bases:

>100_bases
AAGCCGTTATTTTTGCCTATCACGATATGGGATGTCAGGGCGTGCAGGCCGTACTGGATGCAGGATATGAGATTGCCGCA
ATTTTCACTCATGCCGACAA

Product: undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase

Products: NA

Alternate protein names: Undecaprenyl-phosphate Ara4FN transferase; Ara4FN transferase [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MFDAAPIKKVSVVIPVYNEQESLPELIRRTTTACESLGKAWEILLIDDGSSDSSAELMVKASQEADSHIISILLNRNYGQ
HAAIMAGFSHVSGDLIITLDADLQNPPEEIPRLVAKADEGFDVVGTVRQNRQDSLFRKSASKIINLLIQRTTGKAMGDYG
CMLRAYRRPIIDTMLRCHERSTFIPILANIFARRATEIPVHHAEREFGDSKYSFMRLINLMYDLVTCLTTTPLRLLSLLG
SVIAIGGFSLSVLLIVLRLALGPQWAAEGVFMLFAVLFTFIGAQFIGMGLLGEYIGRIYNDVRARPRYFVQQVIYPESTS
FTEESHQ

Sequences:

>Translated_327_residues
MFDAAPIKKVSVVIPVYNEQESLPELIRRTTTACESLGKAWEILLIDDGSSDSSAELMVKASQEADSHIISILLNRNYGQ
HAAIMAGFSHVSGDLIITLDADLQNPPEEIPRLVAKADEGFDVVGTVRQNRQDSLFRKSASKIINLLIQRTTGKAMGDYG
CMLRAYRRPIIDTMLRCHERSTFIPILANIFARRATEIPVHHAEREFGDSKYSFMRLINLMYDLVTCLTTTPLRLLSLLG
SVIAIGGFSLSVLLIVLRLALGPQWAAEGVFMLFAVLFTFIGAQFIGMGLLGEYIGRIYNDVRARPRYFVQQVIYPESTS
FTEESHQ
>Mature_327_residues
MFDAAPIKKVSVVIPVYNEQESLPELIRRTTTACESLGKAWEILLIDDGSSDSSAELMVKASQEADSHIISILLNRNYGQ
HAAIMAGFSHVSGDLIITLDADLQNPPEEIPRLVAKADEGFDVVGTVRQNRQDSLFRKSASKIINLLIQRTTGKAMGDYG
CMLRAYRRPIIDTMLRCHERSTFIPILANIFARRATEIPVHHAEREFGDSKYSFMRLINLMYDLVTCLTTTPLRLLSLLG
SVIAIGGFSLSVLLIVLRLALGPQWAAEGVFMLFAVLFTFIGAQFIGMGLLGEYIGRIYNDVRARPRYFVQQVIYPESTS
FTEESHQ

Specific function: Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides [H]

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family [H]

Homologues:

Organism=Homo sapiens, GI4503363, Length=237, Percent_Identity=28.2700421940928, Blast_Score=98, Evalue=8e-21,
Organism=Escherichia coli, GI1788588, Length=318, Percent_Identity=87.7358490566038, Blast_Score=590, Evalue=1e-170,
Organism=Escherichia coli, GI1788692, Length=312, Percent_Identity=32.6923076923077, Blast_Score=161, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI71999402, Length=225, Percent_Identity=26.6666666666667, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6325441, Length=117, Percent_Identity=29.9145299145299, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24585265, Length=235, Percent_Identity=25.531914893617, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022857
- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: =2.7.8.30 [H]

Molecular weight: Translated: 36507; Mature: 36507

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDAAPIKKVSVVIPVYNEQESLPELIRRTTTACESLGKAWEILLIDDGSSDSSAELMVK
CCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCHHEEEE
ASQEADSHIISILLNRNYGQHAAIMAGFSHVSGDLIITLDADLQNPPEEIPRLVAKADEG
EHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCC
FDVVGTVRQNRQDSLFRKSASKIINLLIQRTTGKAMGDYGCMLRAYRRPIIDTMLRCHER
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
STFIPILANIFARRATEIPVHHAEREFGDSKYSFMRLINLMYDLVTCLTTTPLRLLSLLG
CCHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
SVIAIGGFSLSVLLIVLRLALGPQWAAEGVFMLFAVLFTFIGAQFIGMGLLGEYIGRIYN
HHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVRARPRYFVQQVIYPESTSFTEESHQ
HHHCCHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MFDAAPIKKVSVVIPVYNEQESLPELIRRTTTACESLGKAWEILLIDDGSSDSSAELMVK
CCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCHHEEEE
ASQEADSHIISILLNRNYGQHAAIMAGFSHVSGDLIITLDADLQNPPEEIPRLVAKADEG
EHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCC
FDVVGTVRQNRQDSLFRKSASKIINLLIQRTTGKAMGDYGCMLRAYRRPIIDTMLRCHER
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
STFIPILANIFARRATEIPVHHAEREFGDSKYSFMRLINLMYDLVTCLTTTPLRLLSLLG
CCHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
SVIAIGGFSLSVLLIVLRLALGPQWAAEGVFMLFAVLFTFIGAQFIGMGLLGEYIGRIYN
HHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVRARPRYFVQQVIYPESTSFTEESHQ
HHHCCHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA