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The map label for this gene is yfbQ [H]

Identifier: 29141048

GI number: 29141048

Start: 606480

End: 607694

Strand: Reverse

Name: yfbQ [H]

Synonym: t0533

Alternate gene names: 29141048

Gene position: 607694-606480 (Counterclockwise)

Preceding gene: 29141064

Following gene: 29141047

Centisome position: 12.68

GC content: 51.52

Gene sequence:

>1215_bases
ATGTCCCCCATTGAAAAATCCAGCAAACTCGAAAATGTCTGTTATGACATTCGTGGCCCCGTTCTGAAAGAAGCGAAACG
CCTTGAGGAAGAAGGTAATAAAGTTCTTAAACTGAATATCGGCAACCCCGCCCCCTTCGGATTCGAAGCGCCGGACGAAA
TTCTGGTCGATGTCATTCGTAATTTGCCGACGGCGCAAGGATATTGCGACTCGAAAGGGCTTTATTCCGCCCGTAAAGCG
ATTATGCAGCATTATCAGGCCCGTGGAATGCGCGATGTAACCGTGGAAGATATCTATATCGGTAACGGCGTTTCCGAGCT
GATCGTTCAGGCGATGCAGGCGTTGCTTAACAGTGGCGATGAAATGCTGGTTCCCGCGCCCGATTATCCGTTATGGACAG
CAGCGGTATCGCTCTCCAGCGGCAAGGCGGTACATTATCTTTGCGATGAATCTTCCGACTGGTTCCCGGACCTTGACGAT
ATCCGCGCCAAAATCACCCCACGTACGCGTGGTATTGTCATTATTAATCCAAACAACCCTACTGGCGCCGTCTATTCTAA
AGAATTGTTGATGGAAATTGTCAACATTGCGCGCGAGCATAATCTCATCATCTTCGCCGATGAAATTTATGACAAGATTC
TCTATGACGATGCCGAACATCACTCTATCGCCGCACTGGCGCCTGATCTGCTGACCATCACCTTTAATGGTTTGTCTAAA
ACCTATCGCGTCGCCGGCTTCCGCCAGGGCTGGATGGTGCTGAACGGGCCGAAAAAACATGCGAAAGGCTATATTGAAGG
GCTGGAGATGTTAGCCTCAATGCGCCTGTGCGCCAACGTCCCGGCGCAACATGCTATTCAGACCGCGCTCGGCGGCTATC
AAAGCATTAGCGAATTTATTCTGCCGGGCGGTCGACTGTATGAACAGCGTAACCGCGCCTGGGAGTTGATTAACGATATT
CCCGGCGTTTCCTGCGTAAAACCGCGCGGCGCGTTGTACATGTTCCCCAGGATCGACGCTAAACGTTTTAATATTCACGA
CGACCAGAAGATGGTGCTGGACTTCCTGCTACAGGAAAAGGTGCTGCTGGTGCAAGGTACCGCCTTTAACTGGCCGTGGC
CGGATCACTTCCGCATTGTGACGCTACCGCGTGAAGATGACCTGGAGATGGCCATCAACCGCTTTGGGCGTTTCCTCTCA
GGCTACCATCAATAA

Upstream 100 bases:

>100_bases
TCTTCTGTTCACTCTTCAAAACTCACCGTCGTGGGAGTACATTGTTTCGTGCTGACTTCCACGGCAGGGAGTGGCAATAA
CAGCTAAAAGGTCAAGATTC

Downstream 100 bases:

>100_bases
TCTTAAATTCAGGCTACTTCGGTAGCCTGAATTGCATCTTCATCACCCTCCCCGCACAATGAAGTCTGCCGCAGTGAAAA
CAAAAGGTAATCTATGAAGC

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MSPIEKSSKLENVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPAPFGFEAPDEILVDVIRNLPTAQGYCDSKGLYSARKA
IMQHYQARGMRDVTVEDIYIGNGVSELIVQAMQALLNSGDEMLVPAPDYPLWTAAVSLSSGKAVHYLCDESSDWFPDLDD
IRAKITPRTRGIVIINPNNPTGAVYSKELLMEIVNIAREHNLIIFADEIYDKILYDDAEHHSIAALAPDLLTITFNGLSK
TYRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRLCANVPAQHAIQTALGGYQSISEFILPGGRLYEQRNRAWELINDI
PGVSCVKPRGALYMFPRIDAKRFNIHDDQKMVLDFLLQEKVLLVQGTAFNWPWPDHFRIVTLPREDDLEMAINRFGRFLS
GYHQ

Sequences:

>Translated_404_residues
MSPIEKSSKLENVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPAPFGFEAPDEILVDVIRNLPTAQGYCDSKGLYSARKA
IMQHYQARGMRDVTVEDIYIGNGVSELIVQAMQALLNSGDEMLVPAPDYPLWTAAVSLSSGKAVHYLCDESSDWFPDLDD
IRAKITPRTRGIVIINPNNPTGAVYSKELLMEIVNIAREHNLIIFADEIYDKILYDDAEHHSIAALAPDLLTITFNGLSK
TYRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRLCANVPAQHAIQTALGGYQSISEFILPGGRLYEQRNRAWELINDI
PGVSCVKPRGALYMFPRIDAKRFNIHDDQKMVLDFLLQEKVLLVQGTAFNWPWPDHFRIVTLPREDDLEMAINRFGRFLS
GYHQ
>Mature_403_residues
SPIEKSSKLENVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPAPFGFEAPDEILVDVIRNLPTAQGYCDSKGLYSARKAI
MQHYQARGMRDVTVEDIYIGNGVSELIVQAMQALLNSGDEMLVPAPDYPLWTAAVSLSSGKAVHYLCDESSDWFPDLDDI
RAKITPRTRGIVIINPNNPTGAVYSKELLMEIVNIAREHNLIIFADEIYDKILYDDAEHHSIAALAPDLLTITFNGLSKT
YRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRLCANVPAQHAIQTALGGYQSISEFILPGGRLYEQRNRAWELINDIP
GVSCVKPRGALYMFPRIDAKRFNIHDDQKMVLDFLLQEKVLLVQGTAFNWPWPDHFRIVTLPREDDLEMAINRFGRFLSG
YHQ

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=382, Percent_Identity=26.7015706806283, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI19263340, Length=463, Percent_Identity=25.2699784017279, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI215599424, Length=368, Percent_Identity=26.6304347826087, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI4885351, Length=448, Percent_Identity=24.1071428571429, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI95147551, Length=171, Percent_Identity=28.0701754385965, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI169881279, Length=171, Percent_Identity=28.0701754385965, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI56713256, Length=235, Percent_Identity=26.3829787234043, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI56713254, Length=235, Percent_Identity=26.3829787234043, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI169881281, Length=161, Percent_Identity=29.8136645962733, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1788627, Length=404, Percent_Identity=96.5346534653465, Blast_Score=818, Evalue=0.0,
Organism=Escherichia coli, GI1788722, Length=377, Percent_Identity=25.7294429708223, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1786816, Length=225, Percent_Identity=25.3333333333333, Blast_Score=79, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17567663, Length=369, Percent_Identity=29.5392953929539, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI71981209, Length=460, Percent_Identity=25, Blast_Score=111, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI71994472, Length=205, Percent_Identity=29.2682926829268, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71994476, Length=205, Percent_Identity=29.2682926829268, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71981215, Length=293, Percent_Identity=26.6211604095563, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17567369, Length=178, Percent_Identity=28.6516853932584, Blast_Score=83, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6320317, Length=360, Percent_Identity=27.7777777777778, Blast_Score=133, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6323118, Length=357, Percent_Identity=27.1708683473389, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6322401, Length=303, Percent_Identity=24.4224422442244, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI18859735, Length=376, Percent_Identity=26.3297872340426, Blast_Score=148, Evalue=5e-36,
Organism=Drosophila melanogaster, GI24641770, Length=460, Percent_Identity=26.5217391304348, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24641760, Length=460, Percent_Identity=26.5217391304348, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24641768, Length=460, Percent_Identity=26.5217391304348, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24641766, Length=460, Percent_Identity=26.5217391304348, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24641764, Length=460, Percent_Identity=26.5217391304348, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI45551451, Length=460, Percent_Identity=26.5217391304348, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI28573069, Length=230, Percent_Identity=25.2173913043478, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24646114, Length=230, Percent_Identity=25.2173913043478, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28573067, Length=230, Percent_Identity=25.2173913043478, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28573065, Length=230, Percent_Identity=25.2173913043478, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 45492; Mature: 45361

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPIEKSSKLENVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPAPFGFEAPDEILVDVIR
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPTAQGYCDSKGLYSARKAIMQHYQARGMRDVTVEDIYIGNGVSELIVQAMQALLNSGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCC
EMLVPAPDYPLWTAAVSLSSGKAVHYLCDESSDWFPDLDDIRAKITPRTRGIVIINPNNP
CEEEECCCCCHHHHEEECCCCCEEEEEECCCCCCCCCHHHHHEEECCCCCEEEEECCCCC
TGAVYSKELLMEIVNIAREHNLIIFADEIYDKILYDDAEHHSIAALAPDLLTITFNGLSK
CCHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHCCCCCCCCHHHHCCCEEEEEECCCCH
TYRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRLCANVPAQHAIQTALGGYQSISEFI
HHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHH
LPGGRLYEQRNRAWELINDIPGVSCVKPRGALYMFPRIDAKRFNIHDDQKMVLDFLLQEK
CCCHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCC
VLLVQGTAFNWPWPDHFRIVTLPREDDLEMAINRFGRFLSGYHQ
EEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SPIEKSSKLENVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPAPFGFEAPDEILVDVIR
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPTAQGYCDSKGLYSARKAIMQHYQARGMRDVTVEDIYIGNGVSELIVQAMQALLNSGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCC
EMLVPAPDYPLWTAAVSLSSGKAVHYLCDESSDWFPDLDDIRAKITPRTRGIVIINPNNP
CEEEECCCCCHHHHEEECCCCCEEEEEECCCCCCCCCHHHHHEEECCCCCEEEEECCCCC
TGAVYSKELLMEIVNIAREHNLIIFADEIYDKILYDDAEHHSIAALAPDLLTITFNGLSK
CCHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHCCCCCCCCHHHHCCCEEEEEECCCCH
TYRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRLCANVPAQHAIQTALGGYQSISEFI
HHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHH
LPGGRLYEQRNRAWELINDIPGVSCVKPRGALYMFPRIDAKRFNIHDDQKMVLDFLLQEK
CCCHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCC
VLLVQGTAFNWPWPDHFRIVTLPREDDLEMAINRFGRFLSGYHQ
EEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]