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The map label for this gene is pta [H]

Identifier: 29141041

GI number: 29141041

Start: 598328

End: 600472

Strand: Reverse

Name: pta [H]

Synonym: t0526

Alternate gene names: 29141041

Gene position: 600472-598328 (Counterclockwise)

Preceding gene: 29141042

Following gene: 29141040

Centisome position: 12.53

GC content: 58.0

Gene sequence:

>2145_bases
GTGTCCCGTATTATTATGCTGATCCCTACCGGAACCAGCGTCGGTCTGACCAGCGTCAGCCTCGGCGTCATCCGTGCTAT
GGAACGCAAAGGCGTTCGTCTGAGCGTCTTTAAGCCTATCGCCCAGCCTCGCGCTGGCGGCGATGCGCCTGACCAGACCA
CCACTATCGTTCGCGCGAACTCTACCCTGCCGGCGGCTGAACCGCTGAAGATGAGCCACGTTGAATCTCTGCTCTCCAGC
AACCAGAAAGACGTGCTGATGGAAGAGATCATCGCAAACTACCATGCGAATACCAAAGACGCGGAAGTGGTGCTGGTTGA
AGGTCTGGTTCCGACCCGTAAACATCAGTTCGCTCAGTCTCTGAACTATGAAATCGCGAAAACGCTGAATGCGGAAATCG
TTTTTGTCATGTCTCAGGGTACCGACACGCCAGAACAGCTGAACGAGCGTATCGAACTGACGCGCAGCAGCTTCGGCGGC
GCGAAAAACACCAACATCACCGGCGTTATCATCAACAAACTGAATGCGCCGGTTGATGAACAAGGCCGTACTCGCCCGGA
TCTGTCAGAGATTTTTGACGACTCTTCCAAAGCGCAGGTGATCAAAATCGATCCTGCTAAACTGCAGGAATCCAGCCCGC
TGCCGGTTCTGGGCGCGGTGCCGTGGAGCTTCGACCTGATTGCGACCCGCGCTATCGATATGGCGCGTCACCTGAACGCC
ACCATCATTAACGAAGGCGATATCAAAACCCGCCGCGTTAAATCCGTTACGTTCTGCGCGCGCAGTATTCCGCATATGCT
GGAGCATTTCCGCGCAGGATCGTTGTTAGTGACCTCAGCTGACCGTCCGGACGTACTGGTCGCAGCTTGCCTGGCCGCGA
TGAACGGCGTAGAAATCGGCGCCCTGCTGCTGACCGGCGGCTATGAAATGGACGCGCGCATTTCTAAACTGTGCGAACGC
GCATTCGCCACCGGTCTGCCGGTCTTTATGGTGAACACCAACACCTGGCAGACTTCGCTGAGCCTGCAAAGCTTCAATCT
GGAAGTTCCGGTTGATGACCATGAGCGCATCGAGAAAGTTCAGGAATACGTCGCGAACTACGTTAACGCTGACTGGATCG
AGTCGCTGACCGCCACTTCCGAGCGTAGCCGTCGTCTCTCTCCGCCGGCGTTCCGCTACCAACTGACTGAGCTGGCGCGT
AAAGCCGGTAAACGCGTAGTGCTGCCGGAAGGCGACGAACCGCGTACCGTCAAAGCGGCGGCAATCTGCGCTGAACGCGG
CATCGCCACTTGCGTACTGCTGGGCAACCCGGATGAAATCAACCGCGTCGCGGCATCTCAGGGCGTAGAGCTGGGCGCAG
GTATTGAAATCGTCGATCCGGAAGTGGTGCGTGAAAGCTATGTCGCTCGCCTGGTTGAGCTGCGTAAGAGCAAAGGCATG
ACCGAACCGGTTGCCCGCGAACAGCTGGAAGACAACGTGGTGCTCGGCACGCTGATGCTGGAGCAAGACGAAGTCGACGG
CCTGGTTTCCGGCGCGGTTCATACCACCGCCAACACCATCCGTCCGCCGCTGCAGCTTATTAAAACGGCGCCGGGTAGCT
CCCTGGTCTCTTCTGTGTTCTTTATGCTACTGCCGGAACAGGTTTACGTTTACGGCGACTGCGCAATCAACCCAGACCCG
ACTGCAGAGCAGCTGGCAGAAATCGCGATTCAGTCTGCGGATTCCGCCATTGCCTTCGGCATCGAACCGCGTGTGGCAAT
GCTCTCCTACTCCACCGGCACCTCTGGCGCGGGCAGCGACGTAGAGAAAGTACGTGAAGCGACGCGTCTGGCGCAGGAAA
AACGTCCTGACCTGATGATCGACGGTCCGTTGCAGTACGACGCCGCGGTCATGGCTGACGTAGCGAAATCCAAAGCGCCG
AACTCGCCGGTTGCGGGTCGCGCTACCGTGTTCATTTTCCCGGATCTGAACACCGGTAACACCACCTACAAAGCGGTACA
GCGTTCTGCCGACCTGATCTCCATCGGGCCGATGCTGCAGGGTATGCGCAAGCCGGTGAACGACCTGTCCCGTGGCGCGC
TGGTTGACGATATCGTCTACACCATCGCCCTGACGGCGATCCAGGCTTCTCAACAGCAGCAGTAA

Upstream 100 bases:

>100_bases
GACGCGAGCCGTCTGACTGCCTGATTTCACACCGCCAGCCTCGCTGGCGGTGCTGTTTTGTAACCCGTCCCCAAAAGACG
GTAACGAAAGAGGATAAACC

Downstream 100 bases:

>100_bases
CAGTAAAAGCTAATGCCGGATGGCGGCGTGAACGCCTTGTCCGGCCTACAGGTGAGATACCGTTGTAGGCCGGATAAGAC
GCGTTAGCATCGCCATCCGG

Product: phosphate acetyltransferase

Products: NA

Alternate protein names: Phosphotransacetylase [H]

Number of amino acids: Translated: 714; Mature: 713

Protein sequence:

>714_residues
MSRIIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPRAGGDAPDQTTTIVRANSTLPAAEPLKMSHVESLLSS
NQKDVLMEEIIANYHANTKDAEVVLVEGLVPTRKHQFAQSLNYEIAKTLNAEIVFVMSQGTDTPEQLNERIELTRSSFGG
AKNTNITGVIINKLNAPVDEQGRTRPDLSEIFDDSSKAQVIKIDPAKLQESSPLPVLGAVPWSFDLIATRAIDMARHLNA
TIINEGDIKTRRVKSVTFCARSIPHMLEHFRAGSLLVTSADRPDVLVAACLAAMNGVEIGALLLTGGYEMDARISKLCER
AFATGLPVFMVNTNTWQTSLSLQSFNLEVPVDDHERIEKVQEYVANYVNADWIESLTATSERSRRLSPPAFRYQLTELAR
KAGKRVVLPEGDEPRTVKAAAICAERGIATCVLLGNPDEINRVAASQGVELGAGIEIVDPEVVRESYVARLVELRKSKGM
TEPVAREQLEDNVVLGTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDCAINPDP
TAEQLAEIAIQSADSAIAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGPLQYDAAVMADVAKSKAP
NSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQASQQQQ

Sequences:

>Translated_714_residues
MSRIIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPRAGGDAPDQTTTIVRANSTLPAAEPLKMSHVESLLSS
NQKDVLMEEIIANYHANTKDAEVVLVEGLVPTRKHQFAQSLNYEIAKTLNAEIVFVMSQGTDTPEQLNERIELTRSSFGG
AKNTNITGVIINKLNAPVDEQGRTRPDLSEIFDDSSKAQVIKIDPAKLQESSPLPVLGAVPWSFDLIATRAIDMARHLNA
TIINEGDIKTRRVKSVTFCARSIPHMLEHFRAGSLLVTSADRPDVLVAACLAAMNGVEIGALLLTGGYEMDARISKLCER
AFATGLPVFMVNTNTWQTSLSLQSFNLEVPVDDHERIEKVQEYVANYVNADWIESLTATSERSRRLSPPAFRYQLTELAR
KAGKRVVLPEGDEPRTVKAAAICAERGIATCVLLGNPDEINRVAASQGVELGAGIEIVDPEVVRESYVARLVELRKSKGM
TEPVAREQLEDNVVLGTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDCAINPDP
TAEQLAEIAIQSADSAIAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGPLQYDAAVMADVAKSKAP
NSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQASQQQQ
>Mature_713_residues
SRIIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPRAGGDAPDQTTTIVRANSTLPAAEPLKMSHVESLLSSN
QKDVLMEEIIANYHANTKDAEVVLVEGLVPTRKHQFAQSLNYEIAKTLNAEIVFVMSQGTDTPEQLNERIELTRSSFGGA
KNTNITGVIINKLNAPVDEQGRTRPDLSEIFDDSSKAQVIKIDPAKLQESSPLPVLGAVPWSFDLIATRAIDMARHLNAT
IINEGDIKTRRVKSVTFCARSIPHMLEHFRAGSLLVTSADRPDVLVAACLAAMNGVEIGALLLTGGYEMDARISKLCERA
FATGLPVFMVNTNTWQTSLSLQSFNLEVPVDDHERIEKVQEYVANYVNADWIESLTATSERSRRLSPPAFRYQLTELARK
AGKRVVLPEGDEPRTVKAAAICAERGIATCVLLGNPDEINRVAASQGVELGAGIEIVDPEVVRESYVARLVELRKSKGMT
EPVAREQLEDNVVLGTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDCAINPDPT
AEQLAEIAIQSADSAIAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGPLQYDAAVMADVAKSKAPN
SPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQASQQQQ

Specific function: Conversion of acetate to acetyl-CoA; second step. [C]

COG id: COG0857

COG function: function code R; BioD-like N-terminal domain of phosphotransacetylase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1788635, Length=714, Percent_Identity=96.6386554621849, Blast_Score=1412, Evalue=0.0,
Organism=Escherichia coli, GI1788800, Length=318, Percent_Identity=38.9937106918239, Blast_Score=219, Evalue=4e-58,
Organism=Escherichia coli, GI1788806, Length=349, Percent_Identity=31.8051575931232, Blast_Score=169, Evalue=7e-43,

Paralogues:

None

Copy number: 1420 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1250 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010766
- InterPro:   IPR016475
- InterPro:   IPR004614
- InterPro:   IPR002505 [H]

Pfam domain/function: PF07085 DRTGG; PF01515 PTA_PTB [H]

EC number: =2.3.1.8 [H]

Molecular weight: Translated: 77265; Mature: 77134

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRIIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPRAGGDAPDQTTTIVRAN
CCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECHHCCCCCCCCCCCCCEEEEEEC
STLPAAEPLKMSHVESLLSSNQKDVLMEEIIANYHANTKDAEVVLVEGLVPTRKHQFAQS
CCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHH
LNYEIAKTLNAEIVFVMSQGTDTPEQLNERIELTRSSFGGAKNTNITGVIINKLNAPVDE
CCHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCC
QGRTRPDLSEIFDDSSKAQVIKIDPAKLQESSPLPVLGAVPWSFDLIATRAIDMARHLNA
CCCCCCCHHHHHCCCCCCEEEEECHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHCCC
TIINEGDIKTRRVKSVTFCARSIPHMLEHFRAGSLLVTSADRPDVLVAACLAAMNGVEIG
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCEEE
ALLLTGGYEMDARISKLCERAFATGLPVFMVNTNTWQTSLSLQSFNLEVPVDDHERIEKV
EEEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEEEEEEEECCCCHHHHHHHH
QEYVANYVNADWIESLTATSERSRRLSPPAFRYQLTELARKAGKRVVLPEGDEPRTVKAA
HHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHH
AICAERGIATCVLLGNPDEINRVAASQGVELGAGIEIVDPEVVRESYVARLVELRKSKGM
HHHHHCCCEEEEEECCCHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHCCC
TEPVAREQLEDNVVLGTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVF
CCHHHHHHHCCCEEEEEEEECCHHHHHHHHCHHHHHHHHCCCHHHHHHCCCCHHHHHHHH
FMLLPEQVYVYGDCAINPDPTAEQLAEIAIQSADSAIAFGIEPRVAMLSYSTGTSGAGSD
HHHCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEECCCCCEEEEEECCCCCCCCHH
VEKVREATRLAQEKRPDLMIDGPLQYDAAVMADVAKSKAPNSPVAGRATVFIFPDLNTGN
HHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCC
TTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQASQQQQ
HHHHHHHHCCCEEEHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SRIIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPRAGGDAPDQTTTIVRAN
CEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECHHCCCCCCCCCCCCCEEEEEEC
STLPAAEPLKMSHVESLLSSNQKDVLMEEIIANYHANTKDAEVVLVEGLVPTRKHQFAQS
CCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHH
LNYEIAKTLNAEIVFVMSQGTDTPEQLNERIELTRSSFGGAKNTNITGVIINKLNAPVDE
CCHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCC
QGRTRPDLSEIFDDSSKAQVIKIDPAKLQESSPLPVLGAVPWSFDLIATRAIDMARHLNA
CCCCCCCHHHHHCCCCCCEEEEECHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHCCC
TIINEGDIKTRRVKSVTFCARSIPHMLEHFRAGSLLVTSADRPDVLVAACLAAMNGVEIG
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCEEE
ALLLTGGYEMDARISKLCERAFATGLPVFMVNTNTWQTSLSLQSFNLEVPVDDHERIEKV
EEEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEEEEEEEECCCCHHHHHHHH
QEYVANYVNADWIESLTATSERSRRLSPPAFRYQLTELARKAGKRVVLPEGDEPRTVKAA
HHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHH
AICAERGIATCVLLGNPDEINRVAASQGVELGAGIEIVDPEVVRESYVARLVELRKSKGM
HHHHHCCCEEEEEECCCHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHCCC
TEPVAREQLEDNVVLGTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVF
CCHHHHHHHCCCEEEEEEEECCHHHHHHHHCHHHHHHHHCCCHHHHHHCCCCHHHHHHHH
FMLLPEQVYVYGDCAINPDPTAEQLAEIAIQSADSAIAFGIEPRVAMLSYSTGTSGAGSD
HHHCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEECCCCCEEEEEECCCCCCCCHH
VEKVREATRLAQEKRPDLMIDGPLQYDAAVMADVAKSKAPNSPVAGRATVFIFPDLNTGN
HHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCC
TTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQASQQQQ
HHHHHHHHCCCEEEHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7883769; 7918659; 9205837; 9278503; 2536666 [H]