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The map label for this gene is talA [H]

Identifier: 29140913

GI number: 29140913

Start: 461026

End: 461976

Strand: Reverse

Name: talA [H]

Synonym: t0386

Alternate gene names: 29140913

Gene position: 461976-461026 (Counterclockwise)

Preceding gene: 29140932

Following gene: 29140912

Centisome position: 9.64

GC content: 53.0

Gene sequence:

>951_bases
ATGAACCAGCTAGACGGCATCAAACAATTCACTACCGTCGTCGCCGACAGCGGCGACATCGAGTCCATCCGCCACTACCA
GCCGCAGGATGCCACGACAAATCCCTCTTTACTGTTAAAAGCCGCCGGGCTTGAGCAGTATGGTCATTTGATTGAGGATG
CGATTGCCTGGGGAAAAAAACACGGCGGTACGCAGGAACAGCAGGTTGCGGCAGCCAGCGATAAACTGGCGGTTAATTTT
GGCGCGGAAATACTGAAAAGTATTCCCGGTCGCGTCTCCACTGAAGTCGACGTGCGGTTATCGTTCGATAAAGAAAAAAG
TATCGAGAAAGCACGCCATCTGGTGGATCTCTACCAGCAGCAGGATGTTGATAAATCACGCATTCTGATCAAGCTCGCCG
CGACCTGGGAAGGTATTCGCGCCGCCGAACAGCTCGAAAAAGAAGGCATTAATTGCAACCTGACGTTGTTGTTCTCTTTT
GCCCAGGCGCGCGCCTGCGCCGAAGCGGGCGTCTATTTAATCTCTCCGTTCGTGGGCCGAATTTACGACTGGTATCAGGC
GCGTAGTCCGCTGGAGCCGTATGTCGTGGAGGAAGATCCCGGCGTGAAATCGGTACGCAATATCTACGATTACTTTAAAC
AGCATCGCTATGAAACCATCGTGATGGGTGCAAGTTTCCGCCGTACTGAGCAAATCCTCGCGCTAACCGGCTGCGATCGA
CTGACTATCTCCCCTAACCTGCTTAAAGAGCTGAAAGAAAAAGAAGAACCGGTGATCCGTAAACTGGTGCCTTCCTCGCA
GATGTTCCACCGTCCTACGCCAATGACGGAAGCGGAGTTCCGCTGGGAACATAATCAGGACGCGATGGCCGTAGAGAAGC
TGTCGGAAGGTATCCGCCTTTTCGCCGTTGACCAGCGCAAACTGGAAGACCTGCTTGCCGCCAAACTATAA

Upstream 100 bases:

>100_bases
TGCCTGTCTGCTATGCTTTTTGGTTATGTAGTGTATCAATCTTTCAGAAGTGTGAATCAACACACTCATCTAACACTTTA
CTTTTCAAGGAGTATTTCCT

Downstream 100 bases:

>100_bases
ACCTTGCATGGAGTGATTTATGTCCCGTAAAGACCTTGCCAATGCGATTCGTGCGCTGAGCATGGATGCCGTTCAAAAAG
CCAATTCCGGGCACCCCGGC

Product: transaldolase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MNQLDGIKQFTTVVADSGDIESIRHYQPQDATTNPSLLLKAAGLEQYGHLIEDAIAWGKKHGGTQEQQVAAASDKLAVNF
GAEILKSIPGRVSTEVDVRLSFDKEKSIEKARHLVDLYQQQDVDKSRILIKLAATWEGIRAAEQLEKEGINCNLTLLFSF
AQARACAEAGVYLISPFVGRIYDWYQARSPLEPYVVEEDPGVKSVRNIYDYFKQHRYETIVMGASFRRTEQILALTGCDR
LTISPNLLKELKEKEEPVIRKLVPSSQMFHRPTPMTEAEFRWEHNQDAMAVEKLSEGIRLFAVDQRKLEDLLAAKL

Sequences:

>Translated_316_residues
MNQLDGIKQFTTVVADSGDIESIRHYQPQDATTNPSLLLKAAGLEQYGHLIEDAIAWGKKHGGTQEQQVAAASDKLAVNF
GAEILKSIPGRVSTEVDVRLSFDKEKSIEKARHLVDLYQQQDVDKSRILIKLAATWEGIRAAEQLEKEGINCNLTLLFSF
AQARACAEAGVYLISPFVGRIYDWYQARSPLEPYVVEEDPGVKSVRNIYDYFKQHRYETIVMGASFRRTEQILALTGCDR
LTISPNLLKELKEKEEPVIRKLVPSSQMFHRPTPMTEAEFRWEHNQDAMAVEKLSEGIRLFAVDQRKLEDLLAAKL
>Mature_316_residues
MNQLDGIKQFTTVVADSGDIESIRHYQPQDATTNPSLLLKAAGLEQYGHLIEDAIAWGKKHGGTQEQQVAAASDKLAVNF
GAEILKSIPGRVSTEVDVRLSFDKEKSIEKARHLVDLYQQQDVDKSRILIKLAATWEGIRAAEQLEKEGINCNLTLLFSF
AQARACAEAGVYLISPFVGRIYDWYQARSPLEPYVVEEDPGVKSVRNIYDYFKQHRYETIVMGASFRRTEQILALTGCDR
LTISPNLLKELKEKEEPVIRKLVPSSQMFHRPTPMTEAEFRWEHNQDAMAVEKLSEGIRLFAVDQRKLEDLLAAKL

Specific function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway [H]

COG id: COG0176

COG function: function code G; Transaldolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transaldolase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI5803187, Length=317, Percent_Identity=58.9905362776025, Blast_Score=367, Evalue=1e-102,
Organism=Escherichia coli, GI1788807, Length=316, Percent_Identity=89.5569620253165, Blast_Score=593, Evalue=1e-171,
Organism=Escherichia coli, GI1786189, Length=312, Percent_Identity=62.5, Blast_Score=414, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI25153750, Length=319, Percent_Identity=53.2915360501567, Blast_Score=340, Evalue=4e-94,
Organism=Caenorhabditis elegans, GI25153752, Length=165, Percent_Identity=52.1212121212121, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17570473, Length=97, Percent_Identity=50.5154639175258, Blast_Score=88, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6323386, Length=321, Percent_Identity=56.6978193146417, Blast_Score=326, Evalue=4e-90,
Organism=Saccharomyces cerevisiae, GI6321480, Length=314, Percent_Identity=52.2292993630573, Blast_Score=322, Evalue=6e-89,
Organism=Drosophila melanogaster, GI45549185, Length=319, Percent_Identity=57.6802507836991, Blast_Score=364, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001585
- InterPro:   IPR004730
- InterPro:   IPR018225 [H]

Pfam domain/function: PF00923 Transaldolase [H]

EC number: =2.2.1.2 [H]

Molecular weight: Translated: 35750; Mature: 35750

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS01054 TRANSALDOLASE_1 ; PS00958 TRANSALDOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQLDGIKQFTTVVADSGDIESIRHYQPQDATTNPSLLLKAAGLEQYGHLIEDAIAWGKK
CCCCHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHEEEECCHHHHHHHHHHHHHHHHC
HGGTQEQQVAAASDKLAVNFGAEILKSIPGRVSTEVDVRLSFDKEKSIEKARHLVDLYQQ
CCCCHHHHHHHHCCCEEEHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHH
QDVDKSRILIKLAATWEGIRAAEQLEKEGINCNLTLLFSFAQARACAEAGVYLISPFVGR
CCCCCHHEEEEEEHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHHH
IYDWYQARSPLEPYVVEEDPGVKSVRNIYDYFKQHRYETIVMGASFRRTEQILALTGCDR
HHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHEEECCCC
LTISPNLLKELKEKEEPVIRKLVPSSQMFHRPTPMTEAEFRWEHNQDAMAVEKLSEGIRL
EEECHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHCCCCCCCHHHHHHHHCCCEE
FAVDQRKLEDLLAAKL
EEECHHHHHHHHHHCC
>Mature Secondary Structure
MNQLDGIKQFTTVVADSGDIESIRHYQPQDATTNPSLLLKAAGLEQYGHLIEDAIAWGKK
CCCCHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHEEEECCHHHHHHHHHHHHHHHHC
HGGTQEQQVAAASDKLAVNFGAEILKSIPGRVSTEVDVRLSFDKEKSIEKARHLVDLYQQ
CCCCHHHHHHHHCCCEEEHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHH
QDVDKSRILIKLAATWEGIRAAEQLEKEGINCNLTLLFSFAQARACAEAGVYLISPFVGR
CCCCCHHEEEEEEHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHHH
IYDWYQARSPLEPYVVEEDPGVKSVRNIYDYFKQHRYETIVMGASFRRTEQILALTGCDR
HHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHEEECCCC
LTISPNLLKELKEKEEPVIRKLVPSSQMFHRPTPMTEAEFRWEHNQDAMAVEKLSEGIRL
EEECHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHCCCCCCCHHHHHHHHCCCEE
FAVDQRKLEDLLAAKL
EEECHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA