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The map label for this gene is hscB [H]

Identifier: 29140849

GI number: 29140849

Start: 360246

End: 360761

Strand: Direct

Name: hscB [H]

Synonym: t0316

Alternate gene names: 29140849

Gene position: 360246-360761 (Clockwise)

Preceding gene: 29140848

Following gene: 29140850

Centisome position: 7.52

GC content: 54.46

Gene sequence:

>516_bases
ATGGATTACTTCACCCTCTTTGGCTTACCAGCCCGTTATCAGATTGACACCCAGGCGCTGAGCTTTCGTTTTCAGGATCT
GCAACGCCAGTATCACCCTGACAAATTTGCCAACGGCACTCAGGCGCAGCAGCTTGCCGCCGTCCAGCAATCCGCCACGA
TCAACCAGGCCTGGCAAACGCTGCGTCACCCTTTGACGCGCGCGGAGTATCTGCTTTCCTTACACGGGTTCGATCTGGCC
AGCGAGCAGCATACGGTACGCGACACCGCGTTTCTGATGGAACAACTCACGCTTCGCGAAGAGCTGGACGATATCGAACA
ATCAAAAGACGACGCGCGGCTGGAAAGCTTCATCAAACGCGTACAAAAGATGTTTGATGCTCGTCTTCAGCAAATGGTGG
AACAGTTGGACAACGCCGCGTGGGACGCGGCGGCGGATACGGTGCGCAAACTGCGGTTTCTCGATAAACTGCGAAGCAGC
GCAGAACAACTCGAAGAAAAGCTGCTCGATTTTTAA

Upstream 100 bases:

>100_bases
CGCGCAGACAACGCATCTGCGGCGCGAAGTAAGAAGGTATAACCCCACCGTGGTCGCCTGCGTGTGGGGTTTGTTCTGAC
AGGCTATCCCTGAGAATGTT

Downstream 100 bases:

>100_bases
CTGGAATCTAACATGGCCTTATTACAAATTAGTGAGCCTGGTCTGAGCGCCGCGCCGCATCAGCGTCGTCTGGCGGCGGG
CATCGACTTAGGCACTACCA

Product: co-chaperone HscB

Products: NA

Alternate protein names: Hsc20 [H]

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MDYFTLFGLPARYQIDTQALSFRFQDLQRQYHPDKFANGTQAQQLAAVQQSATINQAWQTLRHPLTRAEYLLSLHGFDLA
SEQHTVRDTAFLMEQLTLREELDDIEQSKDDARLESFIKRVQKMFDARLQQMVEQLDNAAWDAAADTVRKLRFLDKLRSS
AEQLEEKLLDF

Sequences:

>Translated_171_residues
MDYFTLFGLPARYQIDTQALSFRFQDLQRQYHPDKFANGTQAQQLAAVQQSATINQAWQTLRHPLTRAEYLLSLHGFDLA
SEQHTVRDTAFLMEQLTLREELDDIEQSKDDARLESFIKRVQKMFDARLQQMVEQLDNAAWDAAADTVRKLRFLDKLRSS
AEQLEEKLLDF
>Mature_171_residues
MDYFTLFGLPARYQIDTQALSFRFQDLQRQYHPDKFANGTQAQQLAAVQQSATINQAWQTLRHPLTRAEYLLSLHGFDLA
SEQHTVRDTAFLMEQLTLREELDDIEQSKDDARLESFIKRVQKMFDARLQQMVEQLDNAAWDAAADTVRKLRFLDKLRSS
AEQLEEKLLDF

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA [H]

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI50301234, Length=156, Percent_Identity=32.0512820512821, Blast_Score=86, Evalue=2e-17,
Organism=Escherichia coli, GI1788876, Length=171, Percent_Identity=90.6432748538012, Blast_Score=314, Evalue=2e-87,
Organism=Caenorhabditis elegans, GI17541320, Length=141, Percent_Identity=27.6595744680851, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI161084223, Length=169, Percent_Identity=27.810650887574, Blast_Score=81, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640 [H]

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C [H]

EC number: NA

Molecular weight: Translated: 20015; Mature: 20015

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYFTLFGLPARYQIDTQALSFRFQDLQRQYHPDKFANGTQAQQLAAVQQSATINQAWQT
CCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHH
LRHPLTRAEYLLSLHGFDLASEQHTVRDTAFLMEQLTLREELDDIEQSKDDARLESFIKR
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VQKMFDARLQQMVEQLDNAAWDAAADTVRKLRFLDKLRSSAEQLEEKLLDF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDYFTLFGLPARYQIDTQALSFRFQDLQRQYHPDKFANGTQAQQLAAVQQSATINQAWQT
CCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHH
LRHPLTRAEYLLSLHGFDLASEQHTVRDTAFLMEQLTLREELDDIEQSKDDARLESFIKR
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VQKMFDARLQQMVEQLDNAAWDAAADTVRKLRFLDKLRSSAEQLEEKLLDF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA