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The map label for this gene is yfhC [H]

Identifier: 29140823

GI number: 29140823

Start: 326219

End: 326770

Strand: Direct

Name: yfhC [H]

Synonym: t0289

Alternate gene names: 29140823

Gene position: 326219-326770 (Clockwise)

Preceding gene: 29140822

Following gene: 29140825

Centisome position: 6.81

GC content: 56.52

Gene sequence:

>552_bases
ATGCCGCCCGCTTTCATTACCGGAGTTACCTCTTTGTCTGATGTCGAATTAGATCACGAATACTGGATGCGCCACGCGCT
GACGCTGGCGAAACGCGCCTGGGACGAACGCGAGGTTCCGGTTGGCGCGGTATTGGTGCATAACCATCGCGTCATTGGCG
AAGGCTGGAATCGACCCATTGGCCGCCACGATCCTACTGCGCATGCTGAAATAATGGCGCTGCGTCAGGGCGGTCTGGTA
TTGCAGAATTATCGGTTACTGGATACCACGCTGTATGTCACGCTGGAACCCTGTGTGATGTGCGCAGGCGCTATGGTGCA
TAGCCGCATTGGACGCGTTGTCTTTGGCGCGCGCGATGCAAAAACTGGCGCGGCCGGATCGCTAATTGACGTGCTGCACC
ATCCGGGAATGAATCACCGGGTCGAGATTATTGAAGGGGTGTTGCGCGATGAATGTGCGACGCTGCTCAGTGATTTTTTC
CGTATGCGTCGTCAGGAAATTAAAGCTCTGAAGAAAGCCGACCGTGCGGAAGGCGCGGGGCCGGCAGTATAG

Upstream 100 bases:

>100_bases
GGATAACCCGCTGCTTTATTTTTGCCAGCATCGCTGGCGGGTGACGCCGCACGGCGAGTTGCAGCAGCTCGAATAGTGAA
ACGCATAGCGTCTGTGTATA

Downstream 100 bases:

>100_bases
CGCAATGCCGGATAAGACGTTGCGCGTCGCCATCCGATAAGACCATCGCGCTATTTTTCTTCTTTCTTCTGCGGCGTAAA
CAGTAAAGACGGCGAATGCG

Product: tRNA-specific adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MPPAFITGVTSLSDVELDHEYWMRHALTLAKRAWDEREVPVGAVLVHNHRVIGEGWNRPIGRHDPTAHAEIMALRQGGLV
LQNYRLLDTTLYVTLEPCVMCAGAMVHSRIGRVVFGARDAKTGAAGSLIDVLHHPGMNHRVEIIEGVLRDECATLLSDFF
RMRRQEIKALKKADRAEGAGPAV

Sequences:

>Translated_183_residues
MPPAFITGVTSLSDVELDHEYWMRHALTLAKRAWDEREVPVGAVLVHNHRVIGEGWNRPIGRHDPTAHAEIMALRQGGLV
LQNYRLLDTTLYVTLEPCVMCAGAMVHSRIGRVVFGARDAKTGAAGSLIDVLHHPGMNHRVEIIEGVLRDECATLLSDFF
RMRRQEIKALKKADRAEGAGPAV
>Mature_182_residues
PPAFITGVTSLSDVELDHEYWMRHALTLAKRAWDEREVPVGAVLVHNHRVIGEGWNRPIGRHDPTAHAEIMALRQGGLVL
QNYRLLDTTLYVTLEPCVMCAGAMVHSRIGRVVFGARDAKTGAAGSLIDVLHHPGMNHRVEIIEGVLRDECATLLSDFFR
MRRQEIKALKKADRAEGAGPAV

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=164, Percent_Identity=33.5365853658537, Blast_Score=95, Evalue=4e-20,
Organism=Homo sapiens, GI19923945, Length=68, Percent_Identity=47.0588235294118, Blast_Score=65, Evalue=3e-11,
Organism=Escherichia coli, GI145693172, Length=165, Percent_Identity=89.0909090909091, Blast_Score=313, Evalue=5e-87,
Organism=Caenorhabditis elegans, GI17541138, Length=155, Percent_Identity=36.1290322580645, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17554608, Length=97, Percent_Identity=38.1443298969072, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322425, Length=173, Percent_Identity=35.8381502890173, Blast_Score=88, Evalue=8e-19,
Organism=Drosophila melanogaster, GI21355527, Length=146, Percent_Identity=34.2465753424658, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 20289; Mature: 20158

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPAFITGVTSLSDVELDHEYWMRHALTLAKRAWDEREVPVGAVLVHNHRVIGEGWNRPI
CCCCHHCCCCCCHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCEEECCCCCCCC
GRHDPTAHAEIMALRQGGLVLQNYRLLDTTLYVTLEPCVMCAGAMVHSRIGRVVFGARDA
CCCCCCHHHHHHHHHCCCEEEECCEEEHEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCC
KTGAAGSLIDVLHHPGMNHRVEIIEGVLRDECATLLSDFFRMRRQEIKALKKADRAEGAG
CCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PAV
CCC
>Mature Secondary Structure 
PPAFITGVTSLSDVELDHEYWMRHALTLAKRAWDEREVPVGAVLVHNHRVIGEGWNRPI
CCCHHCCCCCCHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCEEECCCCCCCC
GRHDPTAHAEIMALRQGGLVLQNYRLLDTTLYVTLEPCVMCAGAMVHSRIGRVVFGARDA
CCCCCCHHHHHHHHHCCCEEEECCEEEHEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCC
KTGAAGSLIDVLHHPGMNHRVEIIEGVLRDECATLLSDFFRMRRQEIKALKKADRAEGAG
CCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PAV
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]