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The map label for this gene is yccK [H]

Identifier: 29140683

GI number: 29140683

Start: 163388

End: 164377

Strand: Reverse

Name: yccK [H]

Synonym: t0142

Alternate gene names: 29140683

Gene position: 164377-163388 (Counterclockwise)

Preceding gene: 29140685

Following gene: 29140659

Centisome position: 3.43

GC content: 54.04

Gene sequence:

>990_bases
ATGCAATATCGTACATTAGGCGCAAACGGACCGCGAGTGTCAGCCATCGGACTGGGATGTATGGGCATGAGCGCATTTTA
CGGCGCTCATGACGACAGCACCTCAATTAAGACGCTACATTATGCGTTAGATCAGGGGGTAACACTGCTCGATACCGCAG
ATATGTATGGCCCTTATACCAATGAAAGGTTAGTCGGAAGAGCCATCGCCGATCGTCGCGATCGGGTATTTTTAGCGACG
AAATTTGGTATCGTTCTCGACCCTGCTAACCCTATGGCGCGTGGCGTCAATGGCAGACCGGAGTACGTTCGCCGTAGTTG
TGAGCAAAGCCTGCAACGCCTGGGGGTCGATCATATCGATCTGTACTATCAACATCGCGTTGATCCATCAGTTCCCATAG
AAGAGACTGTCGGTGCAATGGCGGACCTGGTGCGCGAGGGAAAAGTGCGTTATCTCGGGCTATCCGAAGCATCAACGCAA
ACGCTGGAACGCGCCCATAACGTTCACCCTATTACCGCGCTGCAAAGTGAGTATTCGCTTTGGTCCCGCGAAGCGGAAAT
TTCAGCACTTTCCACCTGTGAACGGTTGGGTATAGGATTCGTCGCTTACAGCCCGCTGGGACGCGGATTTCTGACCGGTA
CGATTAAAACGCCAGAAGATTTTGCTGCGAATGACTTCCGTCGCACAAATCCCAGATTCATGGGTGAGAACTTCTCGCGC
AATTTACGTCTGGCTGAAGCAATAAAACAAATGGCACGCGAAAAAGAGTGTACCCCCGCACAATTAGCGCTGGCCTGGCT
GCTGGCCCGCAACAGGCACCTCGTTCCCATTCCCGGCACCCGCCACTGCGCCAGGGTGGATGAAAACCTCGGCGCGTTAT
CACTGACCCTAAGCCCGCAGGAGCTGGCGGCAATTGAGGCGGTTTTTCCTCACGACGCCGCAGCCGGCCCCCGCTACTGG
CCGGAAATTATGTCGACATTAAATCGCTAA

Upstream 100 bases:

>100_bases
TAAGCCAGCCTTCATAAACCATGCTTATTCCCCCTATTTTTCATCTTATACGCCAGGTATAGACTGCCTGCCATGCACAA
AATATCCTCATGGAGGCAGT

Downstream 100 bases:

>100_bases
TAAGATCGATGGGGATCGTGTTGCGATCCCCCACTAAGGCGCAAATTGGCGTAATTTACGAATAATCGGTTCATTGGCCG
GCGGAAAATCGTCCGTATTC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MQYRTLGANGPRVSAIGLGCMGMSAFYGAHDDSTSIKTLHYALDQGVTLLDTADMYGPYTNERLVGRAIADRRDRVFLAT
KFGIVLDPANPMARGVNGRPEYVRRSCEQSLQRLGVDHIDLYYQHRVDPSVPIEETVGAMADLVREGKVRYLGLSEASTQ
TLERAHNVHPITALQSEYSLWSREAEISALSTCERLGIGFVAYSPLGRGFLTGTIKTPEDFAANDFRRTNPRFMGENFSR
NLRLAEAIKQMAREKECTPAQLALAWLLARNRHLVPIPGTRHCARVDENLGALSLTLSPQELAAIEAVFPHDAAAGPRYW
PEIMSTLNR

Sequences:

>Translated_329_residues
MQYRTLGANGPRVSAIGLGCMGMSAFYGAHDDSTSIKTLHYALDQGVTLLDTADMYGPYTNERLVGRAIADRRDRVFLAT
KFGIVLDPANPMARGVNGRPEYVRRSCEQSLQRLGVDHIDLYYQHRVDPSVPIEETVGAMADLVREGKVRYLGLSEASTQ
TLERAHNVHPITALQSEYSLWSREAEISALSTCERLGIGFVAYSPLGRGFLTGTIKTPEDFAANDFRRTNPRFMGENFSR
NLRLAEAIKQMAREKECTPAQLALAWLLARNRHLVPIPGTRHCARVDENLGALSLTLSPQELAAIEAVFPHDAAAGPRYW
PEIMSTLNR
>Mature_329_residues
MQYRTLGANGPRVSAIGLGCMGMSAFYGAHDDSTSIKTLHYALDQGVTLLDTADMYGPYTNERLVGRAIADRRDRVFLAT
KFGIVLDPANPMARGVNGRPEYVRRSCEQSLQRLGVDHIDLYYQHRVDPSVPIEETVGAMADLVREGKVRYLGLSEASTQ
TLERAHNVHPITALQSEYSLWSREAEISALSTCERLGIGFVAYSPLGRGFLTGTIKTPEDFAANDFRRTNPRFMGENFSR
NLRLAEAIKQMAREKECTPAQLALAWLLARNRHLVPIPGTRHCARVDENLGALSLTLSPQELAAIEAVFPHDAAAGPRYW
PEIMSTLNR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=325, Percent_Identity=27.6923076923077, Blast_Score=121, Evalue=7e-28,
Organism=Homo sapiens, GI4504825, Length=323, Percent_Identity=27.5541795665635, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI27436964, Length=310, Percent_Identity=29.0322580645161, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI27436971, Length=331, Percent_Identity=28.0966767371601, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI27436962, Length=309, Percent_Identity=28.4789644012945, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI27436966, Length=310, Percent_Identity=28.7096774193548, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI223718702, Length=222, Percent_Identity=32.8828828828829, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI41327764, Length=242, Percent_Identity=32.6446280991736, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI41152114, Length=222, Percent_Identity=30.1801801801802, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI87081735, Length=337, Percent_Identity=34.1246290801187, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1789375, Length=325, Percent_Identity=33.2307692307692, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1788070, Length=312, Percent_Identity=32.3717948717949, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1788081, Length=303, Percent_Identity=29.7029702970297, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1789199, Length=349, Percent_Identity=29.2263610315186, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787674, Length=324, Percent_Identity=27.1604938271605, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI48994888, Length=317, Percent_Identity=25.5520504731861, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17564128, Length=330, Percent_Identity=25.4545454545455, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17566692, Length=339, Percent_Identity=25.3687315634218, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI212645785, Length=163, Percent_Identity=30.6748466257669, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=334, Percent_Identity=27.8443113772455, Blast_Score=122, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6325384, Length=296, Percent_Identity=29.0540540540541, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6323998, Length=324, Percent_Identity=25, Blast_Score=105, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6319958, Length=300, Percent_Identity=23, Blast_Score=96, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6322615, Length=255, Percent_Identity=24.7058823529412, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6319951, Length=312, Percent_Identity=23.7179487179487, Blast_Score=85, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24646155, Length=160, Percent_Identity=34.375, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24640980, Length=323, Percent_Identity=24.4582043343653, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI20129731, Length=342, Percent_Identity=26.0233918128655, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24646159, Length=223, Percent_Identity=29.1479820627803, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI45549126, Length=323, Percent_Identity=24.4582043343653, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24657054, Length=335, Percent_Identity=22.3880597014925, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36491; Mature: 36491

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYRTLGANGPRVSAIGLGCMGMSAFYGAHDDSTSIKTLHYALDQGVTLLDTADMYGPYT
CCEEECCCCCCEEEEEEECHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEECHHHCCCCC
NERLVGRAIADRRDRVFLATKFGIVLDPANPMARGVNGRPEYVRRSCEQSLQRLGVDHID
CCHHHHHHHHCCCCEEEEEEECCEEECCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCHHH
LYYQHRVDPSVPIEETVGAMADLVREGKVRYLGLSEASTQTLERAHNVHPITALQSEYSL
HHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHH
WSREAEISALSTCERLGIGFVAYSPLGRGFLTGTIKTPEDFAANDFRRTNPRFMGENFSR
HHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCCCHHHHCCCCCCCCCCCCCCCCCC
NLRLAEAIKQMAREKECTPAQLALAWLLARNRHLVPIPGTRHCARVDENLGALSLTLSPQ
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHCCCCEEEEEECHH
ELAAIEAVFPHDAAAGPRYWPEIMSTLNR
HHHHHHHHCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MQYRTLGANGPRVSAIGLGCMGMSAFYGAHDDSTSIKTLHYALDQGVTLLDTADMYGPYT
CCEEECCCCCCEEEEEEECHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEECHHHCCCCC
NERLVGRAIADRRDRVFLATKFGIVLDPANPMARGVNGRPEYVRRSCEQSLQRLGVDHID
CCHHHHHHHHCCCCEEEEEEECCEEECCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCHHH
LYYQHRVDPSVPIEETVGAMADLVREGKVRYLGLSEASTQTLERAHNVHPITALQSEYSL
HHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHH
WSREAEISALSTCERLGIGFVAYSPLGRGFLTGTIKTPEDFAANDFRRTNPRFMGENFSR
HHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCCCHHHHCCCCCCCCCCCCCCCCCC
NLRLAEAIKQMAREKECTPAQLALAWLLARNRHLVPIPGTRHCARVDENLGALSLTLSPQ
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHCCCCEEEEEECHH
ELAAIEAVFPHDAAAGPRYWPEIMSTLNR
HHHHHHHHCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]