| Definition | Salmonella enterica subsp. enterica serovar Typhi str. Ty2 chromosome, complete genome. |
|---|---|
| Accession | NC_004631 |
| Length | 4,791,961 |
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The map label for this gene is ftsI [H]
Identifier: 29140667
GI number: 29140667
Start: 143132
End: 144898
Strand: Direct
Name: ftsI [H]
Synonym: t0126
Alternate gene names: 29140667
Gene position: 143132-144898 (Clockwise)
Preceding gene: 29140666
Following gene: 29140668
Centisome position: 2.99
GC content: 54.78
Gene sequence:
>1767_bases ATGAAAGCAGCGGCAAAAACGCAAAAATCGAAGCGCCAGGAAGAACAGACCAACTTCATCAGTTGGCGTTTTGCGTTGCT GTGCGGCTGTATTTTACTGGCGCTGGTTTTTTTACTTGGACGCGCGGCGTGGCTACAGATTATCGCCCCGGATATGCTGG TGCGTCAGGGCGATATGCGTTCGCTGCGTGTTCAGGAAGTCTCCACCTCACGCGGTATGATTACCGACCGTTCCGGGCGT CCACTGGCGGTCAGCGTACCGGTTAAGGCGATCTGGGCCGACCCGAAAGAAGTTCATGACGCCGGCGGCATCAGCGTCGG CGATCGCTGGAAAGCGCTTTCTACTGCGCTCAATATTCCGCTCGATCAGCTCTCCGCCCGTATCAACGCCAACCCGAAAG GGCGTTTTATTTATCTGGCGCGCCAGGTAAATCCTGACATGGCGGACTACATCAAAAAACTCAAACTGCCGGGGATTCAT TTGCGTGAAGAATCACGCCGCTACTACCCGTCAGGAGAAGTAACCGCTCACCTCATCGGTTTTACCAACGTTGACAGTCA GGGGATTGAAGGCGTTGAAAAGAGCTTTGATAAGTGGCTTACCGGTCAGCCTGGCGAGCGAATCGTGCGTAAAGACCGCT ATGGCCGCGTGATTGAGGATATCTCCTCCACTGACAGTCAGGCAGCGCACAACCTGGCGTTAAGCATTGATGAACGCTTA CAGGCGCTGGTTTACCGCGAACTGAACAACGCGGTGGCGTTTAACAAGGCGGAATCCGGTAGCGCGGTGCTGGTCGATGT CAATACCGGTGAAGTACTGGCGATGGCGAATAGCCCTTCCTATAACCCCAACAACCTTGCCGGTACGCCGAAAGACGCGA TGCGTAACCGTACCATCACCGACGTGTTTGAACCGGGTTCTACGGTTAAGCCGATGGTGGTGATGACTGCGCTTCAGCGC GGTATCGTCAACGAAAATACGGTGTTGAATACCGTTCCATACCGAATTAACGGCCACGAAATTAAAGACGTGGCGCGCTA CAGCGAATTAACCCTGACTGGGGTTCTACAGAAGTCGAGTAACGTCGGTGTATCCAAACTGGCGTTAGCGATGCCGTCCT CAGCGTTAGTAGATACTTACTCACGTTTTGGGCTAGGAAAGGCGACCAATTTGGGGTTGGTCGGAGAACGCAGTGGCTTA TATCCTCAAAAACAACGGTGGTCCGACATAGAGAGGGCCACCTTCTCTTTCGGCTACGGGCTAATGGTAACGCCGTTACA GTTAGCGCGAGTTTATGCAACGATCGGCAGCTATGGCATTTATCGCCCGCTGTCGATTACCAAAGTTGATCCGCCTGTAC CCGGCGAACGCATCTTCCCTGAATCCACCGTACGCACCGTGGTGCATATGATGGAAAGCGTGGCGCTGCCGGGCGGCGGC GGCGTGAAGGCGGCAATTAAAGGCTACCGTATCGCGATTAAAACCGGTACGGCGAAAAAAGTGGGGCCGGACGGTCGCTA CATCAACAAATACATTGCTTACACCGCAGGCGTCGCGCCTGCGAGTCAGCCGCGCTTCGCGCTGGTGGTTGTCATCAACG ATCCGCAGGCGGGTAAATACTACGGCGGCGCCGTTTCCGCGCCGGTATTTGGTGCCATCATGGGCGGCGTTCTGCGCACC ATGAACATCGAACCGGACGCGCTGGCAACGGGCGAAAAAAATGAATTCGTAATTAATCAAGGCGAGGGAACAGGTGGCAG ATCGTAA
Upstream 100 bases:
>100_bases CAGCCGGGTAGAGCGGATCGCAACGGAAAAGCTGCAAATGCAGCATGTTGATCCGTCCCAAGAAAATATCGTAGTGCAAA AATAAGGATAAACGCGACGC
Downstream 100 bases:
>100_bases TTTGCGCGACCTTCTTGCTCCGTGGGTGGCTGGACTACCCGCGCGAGAACTGCGAGAGATGACGCTCGACAGCCGTGTGG CTGCGGCGGGCGATCTCTTT
Product: penicillin-binding protein 3
Products: NA
Alternate protein names: Penicillin-binding protein 3; PBP-3; Peptidoglycan glycosyltransferase 3 [H]
Number of amino acids: Translated: 588; Mature: 588
Protein sequence:
>588_residues MKAAAKTQKSKRQEEQTNFISWRFALLCGCILLALVFLLGRAAWLQIIAPDMLVRQGDMRSLRVQEVSTSRGMITDRSGR PLAVSVPVKAIWADPKEVHDAGGISVGDRWKALSTALNIPLDQLSARINANPKGRFIYLARQVNPDMADYIKKLKLPGIH LREESRRYYPSGEVTAHLIGFTNVDSQGIEGVEKSFDKWLTGQPGERIVRKDRYGRVIEDISSTDSQAAHNLALSIDERL QALVYRELNNAVAFNKAESGSAVLVDVNTGEVLAMANSPSYNPNNLAGTPKDAMRNRTITDVFEPGSTVKPMVVMTALQR GIVNENTVLNTVPYRINGHEIKDVARYSELTLTGVLQKSSNVGVSKLALAMPSSALVDTYSRFGLGKATNLGLVGERSGL YPQKQRWSDIERATFSFGYGLMVTPLQLARVYATIGSYGIYRPLSITKVDPPVPGERIFPESTVRTVVHMMESVALPGGG GVKAAIKGYRIAIKTGTAKKVGPDGRYINKYIAYTAGVAPASQPRFALVVVINDPQAGKYYGGAVSAPVFGAIMGGVLRT MNIEPDALATGEKNEFVINQGEGTGGRS
Sequences:
>Translated_588_residues MKAAAKTQKSKRQEEQTNFISWRFALLCGCILLALVFLLGRAAWLQIIAPDMLVRQGDMRSLRVQEVSTSRGMITDRSGR PLAVSVPVKAIWADPKEVHDAGGISVGDRWKALSTALNIPLDQLSARINANPKGRFIYLARQVNPDMADYIKKLKLPGIH LREESRRYYPSGEVTAHLIGFTNVDSQGIEGVEKSFDKWLTGQPGERIVRKDRYGRVIEDISSTDSQAAHNLALSIDERL QALVYRELNNAVAFNKAESGSAVLVDVNTGEVLAMANSPSYNPNNLAGTPKDAMRNRTITDVFEPGSTVKPMVVMTALQR GIVNENTVLNTVPYRINGHEIKDVARYSELTLTGVLQKSSNVGVSKLALAMPSSALVDTYSRFGLGKATNLGLVGERSGL YPQKQRWSDIERATFSFGYGLMVTPLQLARVYATIGSYGIYRPLSITKVDPPVPGERIFPESTVRTVVHMMESVALPGGG GVKAAIKGYRIAIKTGTAKKVGPDGRYINKYIAYTAGVAPASQPRFALVVVINDPQAGKYYGGAVSAPVFGAIMGGVLRT MNIEPDALATGEKNEFVINQGEGTGGRS >Mature_588_residues MKAAAKTQKSKRQEEQTNFISWRFALLCGCILLALVFLLGRAAWLQIIAPDMLVRQGDMRSLRVQEVSTSRGMITDRSGR PLAVSVPVKAIWADPKEVHDAGGISVGDRWKALSTALNIPLDQLSARINANPKGRFIYLARQVNPDMADYIKKLKLPGIH LREESRRYYPSGEVTAHLIGFTNVDSQGIEGVEKSFDKWLTGQPGERIVRKDRYGRVIEDISSTDSQAAHNLALSIDERL QALVYRELNNAVAFNKAESGSAVLVDVNTGEVLAMANSPSYNPNNLAGTPKDAMRNRTITDVFEPGSTVKPMVVMTALQR GIVNENTVLNTVPYRINGHEIKDVARYSELTLTGVLQKSSNVGVSKLALAMPSSALVDTYSRFGLGKATNLGLVGERSGL YPQKQRWSDIERATFSFGYGLMVTPLQLARVYATIGSYGIYRPLSITKVDPPVPGERIFPESTVRTVVHMMESVALPGGG GVKAAIKGYRIAIKTGTAKKVGPDGRYINKYIAYTAGVAPASQPRFALVVVINDPQAGKYYGGAVSAPVFGAIMGGVLRT MNIEPDALATGEKNEFVINQGEGTGGRS
Specific function: Cell wall formation. Essential for the formation of a septum of the murein sacculus. Synthesis of cross-linked peptidoglycan from the lipid intermediates [H]
COG id: COG0768
COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2
Gene ontology:
Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side. Note=The bulk of the molecule, except for the N-terminal membrane anchor region, protrudes into the periplasmic space, where it acts on murein (By similarity) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1786272, Length=588, Percent_Identity=96.2585034013605, Blast_Score=1169, Evalue=0.0, Organism=Escherichia coli, GI1786854, Length=648, Percent_Identity=25.462962962963, Blast_Score=139, Evalue=4e-34,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR005311 - InterPro: IPR001460 [H]
Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]
EC number: =2.4.1.129 [H]
Molecular weight: Translated: 63846; Mature: 63846
Theoretical pI: Translated: 10.07; Mature: 10.07
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 2.6 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKAAAKTQKSKRQEEQTNFISWRFALLCGCILLALVFLLGRAAWLQIIAPDMLVRQGDMR CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCC SLRVQEVSTSRGMITDRSGRPLAVSVPVKAIWADPKEVHDAGGISVGDRWKALSTALNIP CEEEEECCCCCCEEECCCCCCEEEECCEEEEECCHHHHHCCCCCCCCCHHHHHHHHHCCC LDQLSARINANPKGRFIYLARQVNPDMADYIKKLKLPGIHLREESRRYYPSGEVTAHLIG HHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCEECCCCCCCCCCCCCEEEEEE FTNVDSQGIEGVEKSFDKWLTGQPGERIVRKDRYGRVIEDISSTDSQAAHNLALSIDERL EECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHEEEHHHHH QALVYRELNNAVAFNKAESGSAVLVDVNTGEVLAMANSPSYNPNNLAGTPKDAMRNRTIT HHHHHHHHHCCEEECCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCHHHHHCCCCH DVFEPGSTVKPMVVMTALQRGIVNENTVLNTVPYRINGHEIKDVARYSELTLTGVLQKSS HHCCCCCCCCHHHHHHHHHHCCCCCCCEEECCCEEECCCHHHHHHHHHHHEEEEEECCCC NVGVSKLALAMPSSALVDTYSRFGLGKATNLGLVGERSGLYPQKQRWSDIERATFSFGYG CCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHCCCC LMVTPLQLARVYATIGSYGIYRPLSITKVDPPVPGERIFPESTVRTVVHMMESVALPGGG HHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC GVKAAIKGYRIAIKTGTAKKVGPDGRYINKYIAYTAGVAPASQPRFALVVVINDPQAGKY CCEEEECCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCC YGGAVSAPVFGAIMGGVLRTMNIEPDALATGEKNEFVINQGEGTGGRS CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCC >Mature Secondary Structure MKAAAKTQKSKRQEEQTNFISWRFALLCGCILLALVFLLGRAAWLQIIAPDMLVRQGDMR CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCC SLRVQEVSTSRGMITDRSGRPLAVSVPVKAIWADPKEVHDAGGISVGDRWKALSTALNIP CEEEEECCCCCCEEECCCCCCEEEECCEEEEECCHHHHHCCCCCCCCCHHHHHHHHHCCC LDQLSARINANPKGRFIYLARQVNPDMADYIKKLKLPGIHLREESRRYYPSGEVTAHLIG HHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCEECCCCCCCCCCCCCEEEEEE FTNVDSQGIEGVEKSFDKWLTGQPGERIVRKDRYGRVIEDISSTDSQAAHNLALSIDERL EECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHEEEHHHHH QALVYRELNNAVAFNKAESGSAVLVDVNTGEVLAMANSPSYNPNNLAGTPKDAMRNRTIT HHHHHHHHHCCEEECCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCHHHHHCCCCH DVFEPGSTVKPMVVMTALQRGIVNENTVLNTVPYRINGHEIKDVARYSELTLTGVLQKSS HHCCCCCCCCHHHHHHHHHHCCCCCCCEEECCCEEECCCHHHHHHHHHHHEEEEEECCCC NVGVSKLALAMPSSALVDTYSRFGLGKATNLGLVGERSGLYPQKQRWSDIERATFSFGYG CCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHCCCC LMVTPLQLARVYATIGSYGIYRPLSITKVDPPVPGERIFPESTVRTVVHMMESVALPGGG HHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC GVKAAIKGYRIAIKTGTAKKVGPDGRYINKYIAYTAGVAPASQPRFALVVVINDPQAGKY CCEEEECCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCC YGGAVSAPVFGAIMGGVLRTMNIEPDALATGEKNEFVINQGEGTGGRS CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]