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The map label for this gene is dedA [H]

Identifier: 28378832

GI number: 28378832

Start: 2022825

End: 2023481

Strand: Direct

Name: dedA [H]

Synonym: lp_2232

Alternate gene names: 28378832

Gene position: 2022825-2023481 (Clockwise)

Preceding gene: 28378828

Following gene: 28378838

Centisome position: 61.14

GC content: 44.6

Gene sequence:

>657_bases
ATGAGTTTTTTAATCGATTTTGTGTTGCACATTGACCAACACTTAGTCACCATCGTGAATAGTTTTGGAATCTGGACCTA
CCTAATTCTCTTTGCCATCATCTTCATTGAGACTGGCGCGGTCATTTTACCATTTCTTCCCGGTGACTCCCTTTTATTTG
CAGCTTGCGCACTCGCCGCTAATCCAACCTATGGCTTACATATCTGGACTTTTGTCATTCTCTTCTTGGTGGCAGCTTTG
GCGGGCGACTCACTTAACTTCTATATTGGTCATTCCCTAGGAGAACGCCTAACTGAAACATCCTGGTTTGGTAGACTGAT
CAATCAAAAACAGCTGGCAAAGTCCGAAAAATTCTTCGAAAAACATGGTGGCATCACCGTGACCATCGCACGCTTCATGC
CAATCATCCGAACCTTTGTCCCATTTGTAGCTGCCAGTTCGCGAATGAAGTATCAACAATTCATTCGCTACAACGTTATC
GGCTGTGTTCTGTGGGTCATTCTCTGTTGTGGTGGTGGCTACTACTTCGGTAATATCCCGTTCGTTAAGGAACACTTTTC
GATGGTTGTCATTGGAATCATCCTGGTTTCACTGATTCCAGCTGTCTTCTCTGCTATCCGCGCACGCTTTAGCCATCCAA
CTGAAAACGAAGATTAA

Upstream 100 bases:

>100_bases
CATTTGTAAGGATTTCTTGCGATTAGCGACTAAGCATAGTATTTCCACTGATTTTCTGGTAACCTAGATAGGATTAATTT
CACATTACTTGGAGGTAACC

Downstream 100 bases:

>100_bases
TCCAATTATAAAAGGCCGATCAGCTAATAATAGCTGACCGGCCTTTTATAATCTAACTTAAAATGCAGTGTCCACTGTAA
ATACTCTTCATTAATCCGCT

Product: integral membrane protein

Products: NA

Alternate protein names: Protein DSG-1 [H]

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MSFLIDFVLHIDQHLVTIVNSFGIWTYLILFAIIFIETGAVILPFLPGDSLLFAACALAANPTYGLHIWTFVILFLVAAL
AGDSLNFYIGHSLGERLTETSWFGRLINQKQLAKSEKFFEKHGGITVTIARFMPIIRTFVPFVAASSRMKYQQFIRYNVI
GCVLWVILCCGGGYYFGNIPFVKEHFSMVVIGIILVSLIPAVFSAIRARFSHPTENED

Sequences:

>Translated_218_residues
MSFLIDFVLHIDQHLVTIVNSFGIWTYLILFAIIFIETGAVILPFLPGDSLLFAACALAANPTYGLHIWTFVILFLVAAL
AGDSLNFYIGHSLGERLTETSWFGRLINQKQLAKSEKFFEKHGGITVTIARFMPIIRTFVPFVAASSRMKYQQFIRYNVI
GCVLWVILCCGGGYYFGNIPFVKEHFSMVVIGIILVSLIPAVFSAIRARFSHPTENED
>Mature_217_residues
SFLIDFVLHIDQHLVTIVNSFGIWTYLILFAIIFIETGAVILPFLPGDSLLFAACALAANPTYGLHIWTFVILFLVAALA
GDSLNFYIGHSLGERLTETSWFGRLINQKQLAKSEKFFEKHGGITVTIARFMPIIRTFVPFVAASSRMKYQQFIRYNVIG
CVLWVILCCGGGYYFGNIPFVKEHFSMVVIGIILVSLIPAVFSAIRARFSHPTENED

Specific function: Unknown

COG id: COG0586

COG function: function code S; Uncharacterized membrane-associated protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dedA family [H]

Homologues:

Organism=Escherichia coli, GI1788656, Length=205, Percent_Identity=49.7560975609756, Blast_Score=212, Evalue=1e-56,
Organism=Escherichia coli, GI1789384, Length=185, Percent_Identity=33.5135135135135, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1789481, Length=154, Percent_Identity=32.4675324675325, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1786252, Length=133, Percent_Identity=29.3233082706767, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015414 [H]

Pfam domain/function: PF09335 SNARE_assoc [H]

EC number: NA

Molecular weight: Translated: 24479; Mature: 24348

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFLIDFVLHIDQHLVTIVNSFGIWTYLILFAIIFIETGAVILPFLPGDSLLFAACALAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHC
NPTYGLHIWTFVILFLVAALAGDSLNFYIGHSLGERLTETSWFGRLINQKQLAKSEKFFE
CCCCHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KHGGITVTIARFMPIIRTFVPFVAASSRMKYQQFIRYNVIGCVLWVILCCGGGYYFGNIP
HHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCC
FVKEHFSMVVIGIILVSLIPAVFSAIRARFSHPTENED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SFLIDFVLHIDQHLVTIVNSFGIWTYLILFAIIFIETGAVILPFLPGDSLLFAACALAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHC
NPTYGLHIWTFVILFLVAALAGDSLNFYIGHSLGERLTETSWFGRLINQKQLAKSEKFFE
CCCCHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KHGGITVTIARFMPIIRTFVPFVAASSRMKYQQFIRYNVIGCVLWVILCCGGGYYFGNIP
HHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCC
FVKEHFSMVVIGIILVSLIPAVFSAIRARFSHPTENED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]