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The map label for this gene is nfrA [H]

Identifier: 28377678

GI number: 28377678

Start: 768998

End: 769750

Strand: Direct

Name: nfrA [H]

Synonym: lp_0829

Alternate gene names: 28377678

Gene position: 768998-769750 (Clockwise)

Preceding gene: 28377677

Following gene: 28377680

Centisome position: 23.24

GC content: 50.86

Gene sequence:

>753_bases
GTGACAAAGAGTGTGAGTGAAACCTTACAGGACCATCGAACGCGGCGACAATTTACCACTGAACCAATTAGTGATGCGCA
ATTCGCGCAAATCATCACAACGGCACAACAAATGCCGACTAGCCAATATTTACAGGCATACAGTTTGATTGAGATCACTC
AGCCTGCACTACGGCAACAATTGGCCACGATTACGATGATGCCAACGGTTGGTGAAAACGGCCGTTTATTAGTTGTGGTT
GCGGACCAACACCGCAACGTCAAGCTAGCACCGGGCGCAACGACGCGTCGGGCACTGAGTGAATTTGACCGCTTTGCTGG
TAGTATTGAAGATGCCACGCTGATTACAGCGGCGATGGTGATGGTCGCTGAAAGCATGGGTCTTGGTAGCGTTGTACTTG
GATCAATTAACAACGACACGCAGGCGGTGATTGACGCACTACACTTGCCGGACTTGACGTTACCCGTCTTTGGGTTGCAG
TTAGGGCACCCAGCGGATGTTCCTGAAAAGAAACCTCGATTAGGGTTGCCCGCTGTGTTGTTTCAAGATACCTATGCTGA
GCCTGCGAGTTATCAGGCGGAGTTGGACCGGTTTGATGGCGTTTTGAATCAGTATTATCAACATCGGAGTAGTCACGCCC
GTACGGAACACTTAGCGCACATGACGCAGGAAGCGACCCACTCAGCGGCCAAACGGCGAGAGTTTTTGACAATCGCTAGG
CAGCAGGGCTTTTTGCCGGAATTAGACCAATAA

Upstream 100 bases:

>100_bases
TCAAGTGTGTCAACGAATTGTGTTTAACTTGAACCTGGACGTGTTGCCACAATTAACGGACTGGTCACGGGAATTACAAC
AAGAACAGGAGCGATTTTAA

Downstream 100 bases:

>100_bases
TCGTTACCATAACACTAATAATTAGAATGGCTGAACGAAAAATAACCGTTAATGTAACGCTCCCATGTCGCTATTAGCTG
ACATGGGAGATTTTTTGGTA

Product: nitro/flavin reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MTKSVSETLQDHRTRRQFTTEPISDAQFAQIITTAQQMPTSQYLQAYSLIEITQPALRQQLATITMMPTVGENGRLLVVV
ADQHRNVKLAPGATTRRALSEFDRFAGSIEDATLITAAMVMVAESMGLGSVVLGSINNDTQAVIDALHLPDLTLPVFGLQ
LGHPADVPEKKPRLGLPAVLFQDTYAEPASYQAELDRFDGVLNQYYQHRSSHARTEHLAHMTQEATHSAAKRREFLTIAR
QQGFLPELDQ

Sequences:

>Translated_250_residues
MTKSVSETLQDHRTRRQFTTEPISDAQFAQIITTAQQMPTSQYLQAYSLIEITQPALRQQLATITMMPTVGENGRLLVVV
ADQHRNVKLAPGATTRRALSEFDRFAGSIEDATLITAAMVMVAESMGLGSVVLGSINNDTQAVIDALHLPDLTLPVFGLQ
LGHPADVPEKKPRLGLPAVLFQDTYAEPASYQAELDRFDGVLNQYYQHRSSHARTEHLAHMTQEATHSAAKRREFLTIAR
QQGFLPELDQ
>Mature_249_residues
TKSVSETLQDHRTRRQFTTEPISDAQFAQIITTAQQMPTSQYLQAYSLIEITQPALRQQLATITMMPTVGENGRLLVVVA
DQHRNVKLAPGATTRRALSEFDRFAGSIEDATLITAAMVMVAESMGLGSVVLGSINNDTQAVIDALHLPDLTLPVFGLQL
GHPADVPEKKPRLGLPAVLFQDTYAEPASYQAELDRFDGVLNQYYQHRSSHARTEHLAHMTQEATHSAAKRREFLTIARQ
QGFLPELDQ

Specific function: Reduces FMN, organic nitro compounds and disulfide DTNB. Involved in maintenance of the cellular redox state and the disulfide stress response [H]

COG id: COG0778

COG function: function code C; Nitroreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the flavin oxidoreductase frp family [H]

Homologues:

Organism=Escherichia coli, GI1787075, Length=217, Percent_Identity=35.9447004608295, Blast_Score=116, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016446
- InterPro:   IPR000415 [H]

Pfam domain/function: PF00881 Nitroreductase [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27708; Mature: 27577

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKSVSETLQDHRTRRQFTTEPISDAQFAQIITTAQQMPTSQYLQAYSLIEITQPALRQQ
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LATITMMPTVGENGRLLVVVADQHRNVKLAPGATTRRALSEFDRFAGSIEDATLITAAMV
HHHHHCCCCCCCCCEEEEEEECCCCCEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHH
MVAESMGLGSVVLGSINNDTQAVIDALHLPDLTLPVFGLQLGHPADVPEKKPRLGLPAVL
HHHHHCCCCCEEEECCCCHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHH
FQDTYAEPASYQAELDRFDGVLNQYYQHRSSHARTEHLAHMTQEATHSAAKRREFLTIAR
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQGFLPELDQ
HCCCCCCCCC
>Mature Secondary Structure 
TKSVSETLQDHRTRRQFTTEPISDAQFAQIITTAQQMPTSQYLQAYSLIEITQPALRQQ
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LATITMMPTVGENGRLLVVVADQHRNVKLAPGATTRRALSEFDRFAGSIEDATLITAAMV
HHHHHCCCCCCCCCEEEEEEECCCCCEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHH
MVAESMGLGSVVLGSINNDTQAVIDALHLPDLTLPVFGLQLGHPADVPEKKPRLGLPAVL
HHHHHCCCCCEEEECCCCHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHH
FQDTYAEPASYQAELDRFDGVLNQYYQHRSSHARTEHLAHMTQEATHSAAKRREFLTIAR
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQGFLPELDQ
HCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: FMN. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA