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The map label for this gene is gapB [H]

Identifier: 28377642

GI number: 28377642

Start: 724979

End: 726001

Strand: Direct

Name: gapB [H]

Synonym: lp_0789

Alternate gene names: 28377642

Gene position: 724979-726001 (Clockwise)

Preceding gene: 28377641

Following gene: 28377643

Centisome position: 21.91

GC content: 41.94

Gene sequence:

>1023_bases
ATGTCTGTAAAAATTGGTATTAATGGTTTCGGACGTATCGGTCGTTTAGCATTCCGTCGTATCTTAGAACTTGGTGAAAA
GTCAAGTGATATCGAAGTTGTTGCTATTAACGATTTAACTTCACCTGCATTGTTGGCTCATCTTTTGAAGTATGACTCAA
CTCATGGTACTTTGAACGCTGACGTTTCAGCAACCGACGATTCAATCGTTGTTAACGGTAAGAACTACCGTGTTTATGCT
GAACCACAAGCACAAAATATTCCTTGGGTTAAGAACGACGGTGTTGACTTCGTTCTCGAATGTACTGGTTTCTACACTTC
AAAGGCTAAGTCACAAGCTCACTTGGACGCTGGTGCAAAGCGTGTCTTGATTTCTGCTCCTGCTGGCTCAGACTTGAAGA
CCATCGTTTACAACGTTAACGATGACATCTTGACTGCAGATGACCGTATCGTTTCTGCTGGTTCATGTACTACTAACTGC
CTTGCACCATTAGCATTCTTTGAAAACAAAGAATTCGGTATCAAGGTTGGTACTATGACTACTATCCATGCTTACACTTC
AACTCAAATGTTACTTGACGGCCCTGTACGTGGTGGTAACTTCCGTGCTGCCCGTGCTGCCGGTGTAAACACTATTCCTC
ATTCAACTGGTGCTGCTAAGGCTCTTGGCTTAGTTATCCCAGAATTGAACGGTAAATTACAAGGCCATGCACAACGTGTT
GGTGTTGTTGATGGTTCATTAACTGAATTAGTTGCTATCTTAGACAAGAAAGTTACTGCTGACGAAGTTAACGCCGCAAT
CAAGAAGCATACTGAAGGTAACGAATCATTTGGTTACAACGATGACGAAATCGTTTCATCTGATGTTATCGGTACTACTT
TCGGTTCAATCTTCGATCCTACTCAAACAGAAGTTACTTCTGATGGTGACAACCAATTAGTTAAGACTGTTGCTTGGTAC
GATAACGAATACGGCTTCACTTGCCAAATGGTACGTACTTTATTGAAGTTCGCCACTCTCTAA

Upstream 100 bases:

>100_bases
TGAGGGTGCGGCTAACTTGATTTTAAAAAAGTAATCTTCTATAGTGAAGTTGCTTTTTAAAATAAAACTATTTTTATTTC
CACAAGGAGGAAATTCTAGT

Downstream 100 bases:

>100_bases
TATTTGATTAGATAGTTAAGAACTTTAAAACCGCATATGGTTTTGACGGCGGGGGGAGGCAAAACTCCTCTTGCCGTTTT
TTTAATTTCAGCAGTCACGA

Product: glyceraldehyde 3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MSVKIGINGFGRIGRLAFRRILELGEKSSDIEVVAINDLTSPALLAHLLKYDSTHGTLNADVSATDDSIVVNGKNYRVYA
EPQAQNIPWVKNDGVDFVLECTGFYTSKAKSQAHLDAGAKRVLISAPAGSDLKTIVYNVNDDILTADDRIVSAGSCTTNC
LAPLAFFENKEFGIKVGTMTTIHAYTSTQMLLDGPVRGGNFRAARAAGVNTIPHSTGAAKALGLVIPELNGKLQGHAQRV
GVVDGSLTELVAILDKKVTADEVNAAIKKHTEGNESFGYNDDEIVSSDVIGTTFGSIFDPTQTEVTSDGDNQLVKTVAWY
DNEYGFTCQMVRTLLKFATL

Sequences:

>Translated_340_residues
MSVKIGINGFGRIGRLAFRRILELGEKSSDIEVVAINDLTSPALLAHLLKYDSTHGTLNADVSATDDSIVVNGKNYRVYA
EPQAQNIPWVKNDGVDFVLECTGFYTSKAKSQAHLDAGAKRVLISAPAGSDLKTIVYNVNDDILTADDRIVSAGSCTTNC
LAPLAFFENKEFGIKVGTMTTIHAYTSTQMLLDGPVRGGNFRAARAAGVNTIPHSTGAAKALGLVIPELNGKLQGHAQRV
GVVDGSLTELVAILDKKVTADEVNAAIKKHTEGNESFGYNDDEIVSSDVIGTTFGSIFDPTQTEVTSDGDNQLVKTVAWY
DNEYGFTCQMVRTLLKFATL
>Mature_339_residues
SVKIGINGFGRIGRLAFRRILELGEKSSDIEVVAINDLTSPALLAHLLKYDSTHGTLNADVSATDDSIVVNGKNYRVYAE
PQAQNIPWVKNDGVDFVLECTGFYTSKAKSQAHLDAGAKRVLISAPAGSDLKTIVYNVNDDILTADDRIVSAGSCTTNCL
APLAFFENKEFGIKVGTMTTIHAYTSTQMLLDGPVRGGNFRAARAAGVNTIPHSTGAAKALGLVIPELNGKLQGHAQRVG
VVDGSLTELVAILDKKVTADEVNAAIKKHTEGNESFGYNDDEIVSSDVIGTTFGSIFDPTQTEVTSDGDNQLVKTVAWYD
NEYGFTCQMVRTLLKFATL

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=340, Percent_Identity=41.4705882352941, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI7657116, Length=337, Percent_Identity=42.7299703264095, Blast_Score=243, Evalue=1e-64,
Organism=Escherichia coli, GI1788079, Length=333, Percent_Identity=45.045045045045, Blast_Score=268, Evalue=3e-73,
Organism=Escherichia coli, GI1789295, Length=343, Percent_Identity=39.9416909620991, Blast_Score=235, Evalue=3e-63,
Organism=Caenorhabditis elegans, GI32566163, Length=344, Percent_Identity=43.6046511627907, Blast_Score=242, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI17568413, Length=344, Percent_Identity=43.6046511627907, Blast_Score=242, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI17534679, Length=346, Percent_Identity=43.3526011560694, Blast_Score=241, Evalue=3e-64,
Organism=Caenorhabditis elegans, GI17534677, Length=346, Percent_Identity=43.3526011560694, Blast_Score=240, Evalue=9e-64,
Organism=Saccharomyces cerevisiae, GI6322409, Length=332, Percent_Identity=45.1807228915663, Blast_Score=265, Evalue=7e-72,
Organism=Saccharomyces cerevisiae, GI6321631, Length=332, Percent_Identity=45.1807228915663, Blast_Score=265, Evalue=8e-72,
Organism=Saccharomyces cerevisiae, GI6322468, Length=332, Percent_Identity=44.578313253012, Blast_Score=261, Evalue=1e-70,
Organism=Drosophila melanogaster, GI19922412, Length=334, Percent_Identity=43.4131736526946, Blast_Score=256, Evalue=1e-68,
Organism=Drosophila melanogaster, GI85725000, Length=337, Percent_Identity=43.3234421364985, Blast_Score=248, Evalue=3e-66,
Organism=Drosophila melanogaster, GI22023983, Length=337, Percent_Identity=43.3234421364985, Blast_Score=248, Evalue=3e-66,
Organism=Drosophila melanogaster, GI17933600, Length=337, Percent_Identity=43.026706231454, Blast_Score=247, Evalue=1e-65,
Organism=Drosophila melanogaster, GI18110149, Length=337, Percent_Identity=43.026706231454, Blast_Score=247, Evalue=1e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36438; Mature: 36307

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKIGINGFGRIGRLAFRRILELGEKSSDIEVVAINDLTSPALLAHLLKYDSTHGTLNA
CEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCEEEC
DVSATDDSIVVNGKNYRVYAEPQAQNIPWVKNDGVDFVLECTGFYTSKAKSQAHLDAGAK
CCCCCCCEEEEECCCEEEEECCCCCCCCEEECCCCEEEEEECCCCCCCCCCHHHHCCCCC
RVLISAPAGSDLKTIVYNVNDDILTADDRIVSAGSCTTNCLAPLAFFENKEFGIKVGTMT
EEEEECCCCCCCEEEEEECCCCEEECCCCEEECCCCCHHHHHHHHHHCCCCCCEEECCEE
TIHAYTSTQMLLDGPVRGGNFRAARAAGVNTIPHSTGAAKALGLVIPELNGKLQGHAQRV
EEEEECCCEEEEECCCCCCCEEEHHHCCCCCCCCCCCCHHHHEEEEECCCCCCCCCEEEE
GVVDGSLTELVAILDKKVTADEVNAAIKKHTEGNESFGYNDDEIVSSDVIGTTFGSIFDP
EECCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHHCCCCHHHHHHHCCCCC
TQTEVTSDGDNQLVKTVAWYDNEYGFTCQMVRTLLKFATL
CCCCCCCCCCHHEEEEEEEECCCCCEEHHHHHHHHHHHCC
>Mature Secondary Structure 
SVKIGINGFGRIGRLAFRRILELGEKSSDIEVVAINDLTSPALLAHLLKYDSTHGTLNA
EEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCEEEC
DVSATDDSIVVNGKNYRVYAEPQAQNIPWVKNDGVDFVLECTGFYTSKAKSQAHLDAGAK
CCCCCCCEEEEECCCEEEEECCCCCCCCEEECCCCEEEEEECCCCCCCCCCHHHHCCCCC
RVLISAPAGSDLKTIVYNVNDDILTADDRIVSAGSCTTNCLAPLAFFENKEFGIKVGTMT
EEEEECCCCCCCEEEEEECCCCEEECCCCEEECCCCCHHHHHHHHHHCCCCCCEEECCEE
TIHAYTSTQMLLDGPVRGGNFRAARAAGVNTIPHSTGAAKALGLVIPELNGKLQGHAQRV
EEEEECCCEEEEECCCCCCCEEEHHHCCCCCCCCCCCCHHHHEEEEECCCCCCCCCEEEE
GVVDGSLTELVAILDKKVTADEVNAAIKKHTEGNESFGYNDDEIVSSDVIGTTFGSIFDP
EECCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHHCCCCHHHHHHHCCCCC
TQTEVTSDGDNQLVKTVAWYDNEYGFTCQMVRTLLKFATL
CCCCCCCCCCHHEEEEEEEECCCCCEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579064 [H]