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The map label for this gene is accA1 [H]

Identifier: 28377473

GI number: 28377473

Start: 565797

End: 566570

Strand: Direct

Name: accA1 [H]

Synonym: lp_0592

Alternate gene names: 28377473

Gene position: 565797-566570 (Clockwise)

Preceding gene: 28377472

Following gene: 28377475

Centisome position: 17.1

GC content: 52.97

Gene sequence:

>774_bases
ATGGATAAACGATTACAGCGATTACGGGCGGCTGATCGGATCAGTGCGCCGACTATCATTCAAGCGTTATTGCCGACAAT
GACGCAACAACGGGGTGACCGCTTATTAGGTCAGGATGCGGCTTTAACGGCGGGCTTTGGGCGCACTGCCACTGGTCGCC
AATTAGCTGTTCTGGGCGTTGACCGGGGTGTTGATATTGCGAGCCGGCGTCGAAAAAACGGGGGAGCATTAACTGTTCCC
GGCTATCGCACGGCGTTAAGAGTCGTAACCCATGCGGCTAAATTTGGGTGGCCGGTCGTTAGCTTAATCAATATGCCAGG
TGCTGATGCGAGCCCCCAATCGGAACGCTATGGTCAGAGTCAGGCCATTGCGGACTTGATTGCGGCGACTGGTCAGCTGA
CCGTACCGAACGTTGTTGTATTTCTCGGTGAGGGCCATAGCGGTGGGGCGTTAGCCTTTGCCAACGCCAACCGCATTATC
ATGCTAGATGATGCACTTTTCAACGTTGCTTCTCCCGAGGCAGTCACCGCGATTTTACATGGGCAACAGACCAGCAGTGA
CGCCATCGATTTATTACCAATGACAGCTAGCGCTTTGCAGTCGCGCGGCTTAGTTGACCTGGTTATTGACCATCAGGATC
AGACATTAGTCGCTGCGATCAACCAGGCGATTGAGACCCAACTTGCCGCACTAGAAGCATTGCCGGCACCGGATCTAATT
GAACAGCGCGAAGCAAAGTTTCAACACTTTTTACAATCTTGGCCGGTCAATTAA

Upstream 100 bases:

>100_bases
CTGTTTAAAAATGGTATGGTGGATGCAGTTGTTGAACGACCTCAATTGCGGTCAACGCTAGGACAAGCATTAGTGAATTA
TGGAATTGGGAGGTCAGCCC

Downstream 100 bases:

>100_bases
AAATAATCATCAAAAAATGGGCTTCTCAGAATTTTTATTCTGAAGAAACCCATTTTTTAATAGTTGCTTAGTACTGATTA
GTCGTGGTTTGATCTTGAGT

Product: acetyl-CoA carboxylase, carboxyl transferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MDKRLQRLRAADRISAPTIIQALLPTMTQQRGDRLLGQDAALTAGFGRTATGRQLAVLGVDRGVDIASRRRKNGGALTVP
GYRTALRVVTHAAKFGWPVVSLINMPGADASPQSERYGQSQAIADLIAATGQLTVPNVVVFLGEGHSGGALAFANANRII
MLDDALFNVASPEAVTAILHGQQTSSDAIDLLPMTASALQSRGLVDLVIDHQDQTLVAAINQAIETQLAALEALPAPDLI
EQREAKFQHFLQSWPVN

Sequences:

>Translated_257_residues
MDKRLQRLRAADRISAPTIIQALLPTMTQQRGDRLLGQDAALTAGFGRTATGRQLAVLGVDRGVDIASRRRKNGGALTVP
GYRTALRVVTHAAKFGWPVVSLINMPGADASPQSERYGQSQAIADLIAATGQLTVPNVVVFLGEGHSGGALAFANANRII
MLDDALFNVASPEAVTAILHGQQTSSDAIDLLPMTASALQSRGLVDLVIDHQDQTLVAAINQAIETQLAALEALPAPDLI
EQREAKFQHFLQSWPVN
>Mature_257_residues
MDKRLQRLRAADRISAPTIIQALLPTMTQQRGDRLLGQDAALTAGFGRTATGRQLAVLGVDRGVDIASRRRKNGGALTVP
GYRTALRVVTHAAKFGWPVVSLINMPGADASPQSERYGQSQAIADLIAATGQLTVPNVVVFLGEGHSGGALAFANANRII
MLDDALFNVASPEAVTAILHGQQTSSDAIDLLPMTASALQSRGLVDLVIDHQDQTLVAAINQAIETQLAALEALPAPDLI
EQREAKFQHFLQSWPVN

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family [H]

Homologues:

Organism=Escherichia coli, GI1786382, Length=227, Percent_Identity=30.8370044052863, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001095
- InterPro:   IPR011763 [H]

Pfam domain/function: PF03255 ACCA [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 27339; Mature: 27339

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKRLQRLRAADRISAPTIIQALLPTMTQQRGDRLLGQDAALTAGFGRTATGRQLAVLGV
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCEEEEEEC
DRGVDIASRRRKNGGALTVPGYRTALRVVTHAAKFGWPVVSLINMPGADASPQSERYGQS
CCCCCHHHHHCCCCCEEECCCHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCHHHCCHH
QAIADLIAATGQLTVPNVVVFLGEGHSGGALAFANANRIIMLDDALFNVASPEAVTAILH
HHHHHHHHHCCCEECCEEEEEEECCCCCCEEEEECCCEEEEEEHHHHCCCCHHHHHHHHC
GQQTSSDAIDLLPMTASALQSRGLVDLVIDHQDQTLVAAINQAIETQLAALEALPAPDLI
CCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
EQREAKFQHFLQSWPVN
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDKRLQRLRAADRISAPTIIQALLPTMTQQRGDRLLGQDAALTAGFGRTATGRQLAVLGV
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCEEEEEEC
DRGVDIASRRRKNGGALTVPGYRTALRVVTHAAKFGWPVVSLINMPGADASPQSERYGQS
CCCCCHHHHHCCCCCEEECCCHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCHHHCCHH
QAIADLIAATGQLTVPNVVVFLGEGHSGGALAFANANRIIMLDDALFNVASPEAVTAILH
HHHHHHHHHCCCEECCEEEEEEECCCCCCEEEEECCCEEEEEEHHHHCCCCHHHHHHHHC
GQQTSSDAIDLLPMTASALQSRGLVDLVIDHQDQTLVAAINQAIETQLAALEALPAPDLI
CCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
EQREAKFQHFLQSWPVN
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA