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The map label for this gene is nagA [H]

Identifier: 28377444

GI number: 28377444

Start: 517651

End: 518787

Strand: Direct

Name: nagA [H]

Synonym: lp_0562

Alternate gene names: 28377444

Gene position: 517651-518787 (Clockwise)

Preceding gene: 28377443

Following gene: 28377445

Centisome position: 15.65

GC content: 44.15

Gene sequence:

>1137_bases
ATGAGCAAAGTGTTAAAACATGCCATCATTTATACTGGTCTAGAAAAGATCGATGACGGCTACATTCGTTTCGGTAAGGA
AATTGAAGCGGTTGGTCCAATGGATGACTACGTGGCCCAACCCGATGATGATATCGAATTTGTGAGTGGCAAAACGATTG
TACCGGGCTTCATTGATGTTCATAGCCATGGTGGTTATAGTTTTGATTCAATGGACGGGAATCCAGCTGAAATTAACGAA
ATGGTTAATGATATGGTTGCCCGCGAAGGTATTACGTCATACTTCTGTACGACCATGACGCAATCCAACGAAAACTTAGA
CCATTCGATGGCCGGTATTAACAAGGCCGCCGATGAAAATCCGGTTATCCAAGGGGTTCATTTGGAAGGCCCATTCATTT
CGGCGACGTTTAAGGGTGCCCAACCTGAAAAGTACATTAAGAATCCTAACGTTGACTTATTAGACAACTGGAACAAGTTG
TCGGGTGGTCGGGTTAAGTTGATTACTTACGCGCCGGAAGATCCTGGTTCGCGTGAATTTGAAAAGTACTGCTTGGAAAA
TGGCATTGTGCCTTCAGTAGGCCACAGTAACGCGACTCGTGAACAATTATTAGCAAGTAAAGCAACTCACGTGACGCATT
TATACAACGCGCAACGTGAATTCAAGCACCGTGAACCAGGTGTTACTGGTCATGCCATGCTTGAAAACAACATGTACTGT
GAATTGATCTGTGATGGGTTCCATATCGTGCCTGACATGATCAAGCTCGCTTACGAACAAAAGGGCGTTGACCGGATCGA
ATTGGTGACTGATTCAATGCGTGCCAAGGGTGAACCCGACGGTATCAGTGAATTAGGTGGTCAAAAAGTGATTGTTAAGG
ATGGTCAAGCACGTCTTGAAGAAGGTAACTTGGCTGGTTCTGTCCTGACATTCATTAATGCCTTCAAGAACATTCAGAAG
TTCACCGGTTGCGGCATTGCTGAAGCGGTTAAGATGGCTTCTGTCAACCAAGCACGTGAATTTGGGTTGACTAAGAAAGG
AACATTGGAAGCCGGTAAAGATGCTGATATCAACATCTTAGATGGCAATCAAGATTTAGTCGCAACATATAGCTACGGTA
AAAAAGCAGCTAAATAA

Upstream 100 bases:

>100_bases
GAAGGAACTTGGCGAATCTTAAATTACTTGGTGCTGGTGGTTGCAAGTTTGGTCTATACCGATTATAATTAAACCAGATA
AATCCAAGGAGGAATTGTTC

Downstream 100 bases:

>100_bases
ATTAGAAGTAAGGGATGAGTACCATGAGTTCGCCAATTTATATTCAAATCCACAACCAAATTAAGCAGGCGATTGAAGCA
GGTCGGTGGGCCGTTGGTGA

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MSKVLKHAIIYTGLEKIDDGYIRFGKEIEAVGPMDDYVAQPDDDIEFVSGKTIVPGFIDVHSHGGYSFDSMDGNPAEINE
MVNDMVAREGITSYFCTTMTQSNENLDHSMAGINKAADENPVIQGVHLEGPFISATFKGAQPEKYIKNPNVDLLDNWNKL
SGGRVKLITYAPEDPGSREFEKYCLENGIVPSVGHSNATREQLLASKATHVTHLYNAQREFKHREPGVTGHAMLENNMYC
ELICDGFHIVPDMIKLAYEQKGVDRIELVTDSMRAKGEPDGISELGGQKVIVKDGQARLEEGNLAGSVLTFINAFKNIQK
FTGCGIAEAVKMASVNQAREFGLTKKGTLEAGKDADINILDGNQDLVATYSYGKKAAK

Sequences:

>Translated_378_residues
MSKVLKHAIIYTGLEKIDDGYIRFGKEIEAVGPMDDYVAQPDDDIEFVSGKTIVPGFIDVHSHGGYSFDSMDGNPAEINE
MVNDMVAREGITSYFCTTMTQSNENLDHSMAGINKAADENPVIQGVHLEGPFISATFKGAQPEKYIKNPNVDLLDNWNKL
SGGRVKLITYAPEDPGSREFEKYCLENGIVPSVGHSNATREQLLASKATHVTHLYNAQREFKHREPGVTGHAMLENNMYC
ELICDGFHIVPDMIKLAYEQKGVDRIELVTDSMRAKGEPDGISELGGQKVIVKDGQARLEEGNLAGSVLTFINAFKNIQK
FTGCGIAEAVKMASVNQAREFGLTKKGTLEAGKDADINILDGNQDLVATYSYGKKAAK
>Mature_377_residues
SKVLKHAIIYTGLEKIDDGYIRFGKEIEAVGPMDDYVAQPDDDIEFVSGKTIVPGFIDVHSHGGYSFDSMDGNPAEINEM
VNDMVAREGITSYFCTTMTQSNENLDHSMAGINKAADENPVIQGVHLEGPFISATFKGAQPEKYIKNPNVDLLDNWNKLS
GGRVKLITYAPEDPGSREFEKYCLENGIVPSVGHSNATREQLLASKATHVTHLYNAQREFKHREPGVTGHAMLENNMYCE
LICDGFHIVPDMIKLAYEQKGVDRIELVTDSMRAKGEPDGISELGGQKVIVKDGQARLEEGNLAGSVLTFINAFKNIQKF
TGCGIAEAVKMASVNQAREFGLTKKGTLEAGKDADINILDGNQDLVATYSYGKKAAK

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=384, Percent_Identity=29.9479166666667, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI224922791, Length=392, Percent_Identity=30.6122448979592, Blast_Score=138, Evalue=7e-33,
Organism=Escherichia coli, GI1786892, Length=363, Percent_Identity=31.404958677686, Blast_Score=152, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17553768, Length=348, Percent_Identity=33.3333333333333, Blast_Score=160, Evalue=9e-40,
Organism=Drosophila melanogaster, GI19920392, Length=387, Percent_Identity=31.5245478036176, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI281361140, Length=399, Percent_Identity=30.8270676691729, Blast_Score=149, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 41403; Mature: 41272

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVLKHAIIYTGLEKIDDGYIRFGKEIEAVGPMDDYVAQPDDDIEFVSGKTIVPGFIDV
CHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCHHHCCCCCCCCEEECCCEECCCEEEE
HSHGGYSFDSMDGNPAEINEMVNDMVAREGITSYFCTTMTQSNENLDHSMAGINKAADEN
ECCCCEECCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCHHHHHHCHHCCCCC
PVIQGVHLEGPFISATFKGAQPEKYIKNPNVDLLDNWNKLSGGRVKLITYAPEDPGSREF
CCEEEEEECCCEEEEEECCCCCHHHHCCCCCCEECCCCCCCCCEEEEEEECCCCCCHHHH
EKYCLENGIVPSVGHSNATREQLLASKATHVTHLYNAQREFKHREPGVTGHAMLENNMYC
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEE
ELICDGFHIVPDMIKLAYEQKGVDRIELVTDSMRAKGEPDGISELGGQKVIVKDGQARLE
EEEECCCHHHHHHHHHHHHHCCCCEEEHHHHHHHCCCCCCCHHHHCCCEEEEECCCHHHH
EGNLAGSVLTFINAFKNIQKFTGCGIAEAVKMASVNQAREFGLTKKGTLEAGKDADINIL
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEE
DGNQDLVATYSYGKKAAK
ECCCCEEEEECCCCCCCC
>Mature Secondary Structure 
SKVLKHAIIYTGLEKIDDGYIRFGKEIEAVGPMDDYVAQPDDDIEFVSGKTIVPGFIDV
HHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCHHHCCCCCCCCEEECCCEECCCEEEE
HSHGGYSFDSMDGNPAEINEMVNDMVAREGITSYFCTTMTQSNENLDHSMAGINKAADEN
ECCCCEECCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCHHHHHHCHHCCCCC
PVIQGVHLEGPFISATFKGAQPEKYIKNPNVDLLDNWNKLSGGRVKLITYAPEDPGSREF
CCEEEEEECCCEEEEEECCCCCHHHHCCCCCCEECCCCCCCCCEEEEEEECCCCCCHHHH
EKYCLENGIVPSVGHSNATREQLLASKATHVTHLYNAQREFKHREPGVTGHAMLENNMYC
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEE
ELICDGFHIVPDMIKLAYEQKGVDRIELVTDSMRAKGEPDGISELGGQKVIVKDGQARLE
EEEECCCHHHHHHHHHHHHHCCCCEEEHHHHHHHCCCCCCCHHHHCCCEEEEECCCHHHH
EGNLAGSVLTFINAFKNIQKFTGCGIAEAVKMASVNQAREFGLTKKGTLEAGKDADINIL
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEE
DGNQDLVATYSYGKKAAK
ECCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA