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The map label for this gene is dtpT [H]

Identifier: 28377435

GI number: 28377435

Start: 508813

End: 510285

Strand: Direct

Name: dtpT [H]

Synonym: lp_0551

Alternate gene names: 28377435

Gene position: 508813-510285 (Clockwise)

Preceding gene: 28377434

Following gene: 28377436

Centisome position: 15.38

GC content: 42.7

Gene sequence:

>1473_bases
TTGGATAAGGAACAAAAGCTGGATCGGTCGTTCTTTGGCCAACCCCGTGGCTTACGGACGTTGTTCTTCACTGAAATGTG
GGAACGATTCAGTTACTACGGGATGCGTGCGCTACTGATCTATTACATGTACTACAGTGTCGCTAAAGGTGGTCTTGGAT
TTGACCAAGTCACCGCAGCATCCATTATGTCAATCTATTCGGCATTAGTTTACGTTTCTAGTGTCCTCGGTGGCTTTCTA
AGTGACCGTGTCTGGGGTAGCCGTAAGACCGTCTTTATTGGTGGGGTCTTCATCATGTTAGGCCACATCGTTTTATCAAC
GCCATTTGGAGTTGGTGCACTATTTGTTTCAATCGCACTTATTGTCATTGGGACTGGGTTATTAAAGCCAAACGTCTCTG
ACATGGTTGGTCAATTGTATACAGTGGAAGATACACGTCGGGATGCAGGTTTTAGTATTTTCGTCTTCGGGATTAACTTA
GGTTCATTGGTTGCACCAGCCTTAGTTGGTCGGATCGGCTTAAATGTTAACTTCCACTTAGGCTTCTCCTTAGCTGCGAT
TGGGATGTTCTTTGGTCTATTGCAATACTACTTTGATGGTAAGAAGAATTTAAGTTCTGCTAGCCTCTATCCAACTGATC
CATTAGAACCCGGTGATTTGAAAAAAATCATGCGGTGGACAATCTTAGGAATCGTTGGGATTGGGTTGATTCTACTATTA
ATGCAATTAATGAATGCTCTTACGTTAGCAAATGTTATTAGTTTAATTAGTACGCTTGTTATCTTGACTCCAATCGTTTA
CTTTATTTTGATGTTAACGTCTGACAAGACTAATGCAACAGAACGTTCACGTGTTCGGGCTTATATCCCATTGTTTATTG
CCGCTGCTTTATTCTGGGCAATTGAAGAACAGGGTTCGTCCGTACTTGCGTTATTTGCAGCTAATCGGGTTAATTTGGAT
CTTGGTTTTACCCATCTAGCTGCTTCTGATTTCCAAATGCTAAACCCATTGTTCATCATGATTTATACAACACCATTCGT
GTGGTTGTGGACTAAGTGGGGTAAAAAACAACCTAGTTCACCAACTAAATTTGCGATTGGGTTGCTATTCGCTGGGGCTT
CTTACCTAGTGATGGCTGTACCTGGAGCACTCTTTGGAACTGCAGGGAAGGTTAGTCCATGGTGGTTAGTTGCCAGTTGG
GCAGTCGTTGAAATTGCTGAAATGTTGATTTCACCAATTGGTTTATCAGTTACCACCAAGCTTGCACCAAAGGCTTTTGC
TTCTCAGATGATGAGTATGTGGTTCCTAACTGATTCGGTTGGTAGTGCGCTTAATGCACAGATTGTCCGTTTCTACTCGA
CGCAAACCGAAGTGCCATATTTTGCGATTACCGGGATTGTTAGTGTCGTTTTAGGGATTATCCTCTTTATGATGGTGCCA
ATGATTAAACGGTCGATGCAAGGCATTCGCTAA

Upstream 100 bases:

>100_bases
GATTAAGGCTAGTATAATAGTTATTATGTTTAATTAAGAAACAAAACTTGTTACTTTTAAACGAAATACAAACTGGTTAA
GAAGTTTGGAGGAATCTCTA

Downstream 100 bases:

>100_bases
ATTGAATATTTACTCGAAGATATGTTATCTTAGTGGTAGCATATCTTTTTTGTTTTGGAGGGGTTGACCATCGTACGAAT
TGCTTTCAGTAGTGATAATC

Product: di-/tripeptide transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MDKEQKLDRSFFGQPRGLRTLFFTEMWERFSYYGMRALLIYYMYYSVAKGGLGFDQVTAASIMSIYSALVYVSSVLGGFL
SDRVWGSRKTVFIGGVFIMLGHIVLSTPFGVGALFVSIALIVIGTGLLKPNVSDMVGQLYTVEDTRRDAGFSIFVFGINL
GSLVAPALVGRIGLNVNFHLGFSLAAIGMFFGLLQYYFDGKKNLSSASLYPTDPLEPGDLKKIMRWTILGIVGIGLILLL
MQLMNALTLANVISLISTLVILTPIVYFILMLTSDKTNATERSRVRAYIPLFIAAALFWAIEEQGSSVLALFAANRVNLD
LGFTHLAASDFQMLNPLFIMIYTTPFVWLWTKWGKKQPSSPTKFAIGLLFAGASYLVMAVPGALFGTAGKVSPWWLVASW
AVVEIAEMLISPIGLSVTTKLAPKAFASQMMSMWFLTDSVGSALNAQIVRFYSTQTEVPYFAITGIVSVVLGIILFMMVP
MIKRSMQGIR

Sequences:

>Translated_490_residues
MDKEQKLDRSFFGQPRGLRTLFFTEMWERFSYYGMRALLIYYMYYSVAKGGLGFDQVTAASIMSIYSALVYVSSVLGGFL
SDRVWGSRKTVFIGGVFIMLGHIVLSTPFGVGALFVSIALIVIGTGLLKPNVSDMVGQLYTVEDTRRDAGFSIFVFGINL
GSLVAPALVGRIGLNVNFHLGFSLAAIGMFFGLLQYYFDGKKNLSSASLYPTDPLEPGDLKKIMRWTILGIVGIGLILLL
MQLMNALTLANVISLISTLVILTPIVYFILMLTSDKTNATERSRVRAYIPLFIAAALFWAIEEQGSSVLALFAANRVNLD
LGFTHLAASDFQMLNPLFIMIYTTPFVWLWTKWGKKQPSSPTKFAIGLLFAGASYLVMAVPGALFGTAGKVSPWWLVASW
AVVEIAEMLISPIGLSVTTKLAPKAFASQMMSMWFLTDSVGSALNAQIVRFYSTQTEVPYFAITGIVSVVLGIILFMMVP
MIKRSMQGIR
>Mature_490_residues
MDKEQKLDRSFFGQPRGLRTLFFTEMWERFSYYGMRALLIYYMYYSVAKGGLGFDQVTAASIMSIYSALVYVSSVLGGFL
SDRVWGSRKTVFIGGVFIMLGHIVLSTPFGVGALFVSIALIVIGTGLLKPNVSDMVGQLYTVEDTRRDAGFSIFVFGINL
GSLVAPALVGRIGLNVNFHLGFSLAAIGMFFGLLQYYFDGKKNLSSASLYPTDPLEPGDLKKIMRWTILGIVGIGLILLL
MQLMNALTLANVISLISTLVILTPIVYFILMLTSDKTNATERSRVRAYIPLFIAAALFWAIEEQGSSVLALFAANRVNLD
LGFTHLAASDFQMLNPLFIMIYTTPFVWLWTKWGKKQPSSPTKFAIGLLFAGASYLVMAVPGALFGTAGKVSPWWLVASW
AVVEIAEMLISPIGLSVTTKLAPKAFASQMMSMWFLTDSVGSALNAQIVRFYSTQTEVPYFAITGIVSVVLGIILFMMVP
MIKRSMQGIR

Specific function: Proton-dependent uptake of di- or tri-peptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI226371746, Length=387, Percent_Identity=26.6149870801034, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI4827008, Length=176, Percent_Identity=32.3863636363636, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI226371748, Length=344, Percent_Identity=26.453488372093, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1790572, Length=414, Percent_Identity=30.6763285024155, Blast_Score=185, Evalue=7e-48,
Organism=Escherichia coli, GI1789911, Length=490, Percent_Identity=26.9387755102041, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1786927, Length=422, Percent_Identity=31.042654028436, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI1787922, Length=500, Percent_Identity=25, Blast_Score=170, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI71987453, Length=197, Percent_Identity=29.9492385786802, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24639583, Length=196, Percent_Identity=30.1020408163265, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24639585, Length=196, Percent_Identity=30.1020408163265, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24639581, Length=196, Percent_Identity=30.1020408163265, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28571102, Length=358, Percent_Identity=27.3743016759777, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI28571100, Length=358, Percent_Identity=27.3743016759777, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI28571098, Length=358, Percent_Identity=27.3743016759777, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 53903; Mature: 53903

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS50850 MFS ; PS01022 PTR2_1 ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKEQKLDRSFFGQPRGLRTLFFTEMWERFSYYGMRALLIYYMYYSVAKGGLGFDQVTAA
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
SIMSIYSALVYVSSVLGGFLSDRVWGSRKTVFIGGVFIMLGHIVLSTPFGVGALFVSIAL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHH
IVIGTGLLKPNVSDMVGQLYTVEDTRRDAGFSIFVFGINLGSLVAPALVGRIGLNVNFHL
HHHHCCCCCCCHHHHHHCEEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEC
GFSLAAIGMFFGLLQYYFDGKKNLSSASLYPTDPLEPGDLKKIMRWTILGIVGIGLILLL
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
MQLMNALTLANVISLISTLVILTPIVYFILMLTSDKTNATERSRVRAYIPLFIAAALFWA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IEEQGSSVLALFAANRVNLDLGFTHLAASDFQMLNPLFIMIYTTPFVWLWTKWGKKQPSS
HHHCCCCEEEEEECCCEEEEECHHHHHHHHHHHHHHHHEEEHHCCHHEEEEHHCCCCCCC
PTKFAIGLLFAGASYLVMAVPGALFGTAGKVSPWWLVASWAVVEIAEMLISPIGLSVTTK
CHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHH
LAPKAFASQMMSMWFLTDSVGSALNAQIVRFYSTQTEVPYFAITGIVSVVLGIILFMMVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
MIKRSMQGIR
HHHHHHCCCC
>Mature Secondary Structure
MDKEQKLDRSFFGQPRGLRTLFFTEMWERFSYYGMRALLIYYMYYSVAKGGLGFDQVTAA
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
SIMSIYSALVYVSSVLGGFLSDRVWGSRKTVFIGGVFIMLGHIVLSTPFGVGALFVSIAL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHH
IVIGTGLLKPNVSDMVGQLYTVEDTRRDAGFSIFVFGINLGSLVAPALVGRIGLNVNFHL
HHHHCCCCCCCHHHHHHCEEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEC
GFSLAAIGMFFGLLQYYFDGKKNLSSASLYPTDPLEPGDLKKIMRWTILGIVGIGLILLL
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
MQLMNALTLANVISLISTLVILTPIVYFILMLTSDKTNATERSRVRAYIPLFIAAALFWA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IEEQGSSVLALFAANRVNLDLGFTHLAASDFQMLNPLFIMIYTTPFVWLWTKWGKKQPSS
HHHCCCCEEEEEECCCEEEEECHHHHHHHHHHHHHHHHEEEHHCCHHEEEEHHCCCCCCC
PTKFAIGLLFAGASYLVMAVPGALFGTAGKVSPWWLVASWAVVEIAEMLISPIGLSVTTK
CHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHH
LAPKAFASQMMSMWFLTDSVGSALNAQIVRFYSTQTEVPYFAITGIVSVVLGIILFMMVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
MIKRSMQGIR
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]