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The map label for this gene is speA [H]

Identifier: 28211871

GI number: 28211871

Start: 2395002

End: 2396462

Strand: Direct

Name: speA [H]

Synonym: CTC02271

Alternate gene names: 28211871

Gene position: 2395002-2396462 (Clockwise)

Preceding gene: 28211852

Following gene: 28211881

Centisome position: 85.56

GC content: 31.35

Gene sequence:

>1461_bases
TTGTACAGATTAAATCAATCAGAAACTCCATTATTTGATGCGTTAATGGAATATGTGAATAGACAAACTATACCTTTTCA
CGTTCCTGGTCATAAAAAAGGAGTAGGAATAGATGAGGAATTTAAAAATTTTATAGGTGAGAATCCTTTTAAAATCGATG
TTACTGTTTTTAAACTAGTGGATAGCTTACATCATCCTACAGGTCCTATAAAAAAAGCTCAAGCATTAGCTTCTGATGCA
TATGGCTCTGATGCTTCATTTTTTTGTATTCATGGTACCTCTGGTGCTATACAGGCAATGATAATGTCTGTGGTGAAATC
TGGTGATAAAATAATTATCCCAAGAAATGTCCATAAATCAGTAACTTCTGGCATTATATTAAGTGGGGCTACCCCCATTT
ATATGCAACCAGAATTAGATAAAAGAGTTGGTATCGCTCATGGCGTTACTCCTGAAACTGTAGAAAAAACATTAAAAGAA
AATCCTGACGCTAAAGCAGTTTTAATAATTAATCCAACTTATTATGGCGTTGCTACTGATATTAAGAAAATAGCAGATAT
AGTTCATAATTATGATATTCCTTTAATTGTAGATGAAGCTCATGGTCCTCATTTAGCTTTTAACGATACACTTCCAATAT
CAGCTATTGAAGCTGGTGCTGATATTTGTTGCCAAAGTACACATAAAATAATAGGTGCTCTAACTCAATGTTCATTACTT
CACGTTCGTTCTAAAAGTATAGATGTAAATAGAGTTCAGCAAATGTTAAGTTTACTTCAAACTACATCTCCTTCATATAT
ATTAATGGCTTCACTTGACTGTGCTAGAAGACAAATAGCTTTAAATGGTAAGGAATTATTAGATAAATCCATAGCTTTAT
CTAACTATGCCCGTGAAGAAATAAATAAAATTCCTGGCTTCTATTGTTTCGGTAAAGAAATTGTTGGAAGACCTGGTGTT
TTTGCTATAGATCCTACTAAAATAACTATAACCTGTAGAGATTTAGGTATTACTGGTTTTGAATTAGATATGATTTTATC
TAACCAATATCACATTCAACTAGAATTATCAGATTTATATAATGGTCTTGCTGTAGGCTCCTTTGGAGATACAAAGGAAA
ATATAGATGCACTAATTAATGCACTAAAAGAAATAAGTAAAGAGTATGTAAATAATGAGAATAAAAAATCTGACTTTATA
GATATACCAGCTATACCAAAGCAAGTTCAAATTCCTAGAGATGCTTTTAATAGTGAAAAAGTAGTTCTTCCTTTAAAAGA
TAGTGAAGGAAGAGTTAGTGGGGAATTTTTAATGGCTTATCCTCCTGGAATACCTGTACTTTGCCCTGGGGAAATAATTA
CTCAAGAAATAATTGATTATATACAAAAATTAAAAGATACTGGTCTTTATGTACAAGGTACAGAAGATTTAGAAGTGAAT
TTTATAAAAGTTGTAAAATAA

Upstream 100 bases:

>100_bases
AATTAAACTATAATTAAAATTGCTTTGCATACATAGACTATAAGTATAAGGCATTGTATTTAAAAACTTTTAACTGATAT
TTGAAAGAAGGTGTTATTAA

Downstream 100 bases:

>100_bases
AGCCCTCACATTAAGGGCTTTACTTTTTTCTATATCTACTTATCTAAAATTTTTTCAATATATTCTTCATTATATATTTT
AATATTTTCTCTTTTAAGTA

Product: arginine/lysine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MYRLNQSETPLFDALMEYVNRQTIPFHVPGHKKGVGIDEEFKNFIGENPFKIDVTVFKLVDSLHHPTGPIKKAQALASDA
YGSDASFFCIHGTSGAIQAMIMSVVKSGDKIIIPRNVHKSVTSGIILSGATPIYMQPELDKRVGIAHGVTPETVEKTLKE
NPDAKAVLIINPTYYGVATDIKKIADIVHNYDIPLIVDEAHGPHLAFNDTLPISAIEAGADICCQSTHKIIGALTQCSLL
HVRSKSIDVNRVQQMLSLLQTTSPSYILMASLDCARRQIALNGKELLDKSIALSNYAREEINKIPGFYCFGKEIVGRPGV
FAIDPTKITITCRDLGITGFELDMILSNQYHIQLELSDLYNGLAVGSFGDTKENIDALINALKEISKEYVNNENKKSDFI
DIPAIPKQVQIPRDAFNSEKVVLPLKDSEGRVSGEFLMAYPPGIPVLCPGEIITQEIIDYIQKLKDTGLYVQGTEDLEVN
FIKVVK

Sequences:

>Translated_486_residues
MYRLNQSETPLFDALMEYVNRQTIPFHVPGHKKGVGIDEEFKNFIGENPFKIDVTVFKLVDSLHHPTGPIKKAQALASDA
YGSDASFFCIHGTSGAIQAMIMSVVKSGDKIIIPRNVHKSVTSGIILSGATPIYMQPELDKRVGIAHGVTPETVEKTLKE
NPDAKAVLIINPTYYGVATDIKKIADIVHNYDIPLIVDEAHGPHLAFNDTLPISAIEAGADICCQSTHKIIGALTQCSLL
HVRSKSIDVNRVQQMLSLLQTTSPSYILMASLDCARRQIALNGKELLDKSIALSNYAREEINKIPGFYCFGKEIVGRPGV
FAIDPTKITITCRDLGITGFELDMILSNQYHIQLELSDLYNGLAVGSFGDTKENIDALINALKEISKEYVNNENKKSDFI
DIPAIPKQVQIPRDAFNSEKVVLPLKDSEGRVSGEFLMAYPPGIPVLCPGEIITQEIIDYIQKLKDTGLYVQGTEDLEVN
FIKVVK
>Mature_486_residues
MYRLNQSETPLFDALMEYVNRQTIPFHVPGHKKGVGIDEEFKNFIGENPFKIDVTVFKLVDSLHHPTGPIKKAQALASDA
YGSDASFFCIHGTSGAIQAMIMSVVKSGDKIIIPRNVHKSVTSGIILSGATPIYMQPELDKRVGIAHGVTPETVEKTLKE
NPDAKAVLIINPTYYGVATDIKKIADIVHNYDIPLIVDEAHGPHLAFNDTLPISAIEAGADICCQSTHKIIGALTQCSLL
HVRSKSIDVNRVQQMLSLLQTTSPSYILMASLDCARRQIALNGKELLDKSIALSNYAREEINKIPGFYCFGKEIVGRPGV
FAIDPTKITITCRDLGITGFELDMILSNQYHIQLELSDLYNGLAVGSFGDTKENIDALINALKEISKEYVNNENKKSDFI
DIPAIPKQVQIPRDAFNSEKVVLPLKDSEGRVSGEFLMAYPPGIPVLCPGEIITQEIIDYIQKLKDTGLYVQGTEDLEVN
FIKVVK

Specific function: Catalyzes the formation of agmatine from arginine [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI221142684, Length=375, Percent_Identity=29.3333333333333, Blast_Score=148, Evalue=7e-37,
Organism=Escherichia coli, GI1786384, Length=566, Percent_Identity=25.4416961130742, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1790573, Length=576, Percent_Identity=26.3888888888889, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI87082193, Length=327, Percent_Identity=27.5229357798165, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786909, Length=318, Percent_Identity=24.5283018867925, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 53524; Mature: 53524

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRLNQSETPLFDALMEYVNRQTIPFHVPGHKKGVGIDEEFKNFIGENPFKIDVTVFKLV
CCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHCCCCEEEEHHHHHHH
DSLHHPTGPIKKAQALASDAYGSDASFFCIHGTSGAIQAMIMSVVKSGDKIIIPRNVHKS
HHHCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEECCCHHHH
VTSGIILSGATPIYMQPELDKRVGIAHGVTPETVEKTLKENPDAKAVLIINPTYYGVATD
HHCCEEEECCCCEEECCCCHHHCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCHHHH
IKKIADIVHNYDIPLIVDEAHGPHLAFNDTLPISAIEAGADICCQSTHKIIGALTQCSLL
HHHHHHHHHCCCCCEEEECCCCCEEEECCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHEE
HVRSKSIDVNRVQQMLSLLQTTSPSYILMASLDCARRQIALNGKELLDKSIALSNYAREE
EECCCCCCHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHCCCHHHHHHHHHHHHHHHHH
INKIPGFYCFGKEIVGRPGVFAIDPTKITITCRDLGITGFELDMILSNQYHIQLELSDLY
HHHCCCEEEECHHHCCCCCEEEECCCEEEEEEEECCCCCEEEEEEECCCEEEEEEHHHHH
NGLAVGSFGDTKENIDALINALKEISKEYVNNENKKSDFIDIPAIPKQVQIPRDAFNSEK
CCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCEECCHHHCCCCE
VVLPLKDSEGRVSGEFLMAYPPGIPVLCPGEIITQEIIDYIQKLKDTGLYVQGTEDLEVN
EEEEECCCCCCCCCCEEEEECCCCCEECCHHHHHHHHHHHHHHHHHCCEEEECCCCCEEE
FIKVVK
EEEEEC
>Mature Secondary Structure
MYRLNQSETPLFDALMEYVNRQTIPFHVPGHKKGVGIDEEFKNFIGENPFKIDVTVFKLV
CCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHCCCCEEEEHHHHHHH
DSLHHPTGPIKKAQALASDAYGSDASFFCIHGTSGAIQAMIMSVVKSGDKIIIPRNVHKS
HHHCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEECCCHHHH
VTSGIILSGATPIYMQPELDKRVGIAHGVTPETVEKTLKENPDAKAVLIINPTYYGVATD
HHCCEEEECCCCEEECCCCHHHCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCHHHH
IKKIADIVHNYDIPLIVDEAHGPHLAFNDTLPISAIEAGADICCQSTHKIIGALTQCSLL
HHHHHHHHHCCCCCEEEECCCCCEEEECCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHEE
HVRSKSIDVNRVQQMLSLLQTTSPSYILMASLDCARRQIALNGKELLDKSIALSNYAREE
EECCCCCCHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHCCCHHHHHHHHHHHHHHHHH
INKIPGFYCFGKEIVGRPGVFAIDPTKITITCRDLGITGFELDMILSNQYHIQLELSDLY
HHHCCCEEEECHHHCCCCCEEEECCCEEEEEEEECCCCCEEEEEEECCCEEEEEEHHHHH
NGLAVGSFGDTKENIDALINALKEISKEYVNNENKKSDFIDIPAIPKQVQIPRDAFNSEK
CCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCEECCHHHCCCCE
VVLPLKDSEGRVSGEFLMAYPPGIPVLCPGEIITQEIIDYIQKLKDTGLYVQGTEDLEVN
EEEEECCCCCCCCCCEEEEECCCCCEECCHHHHHHHHHHHHHHHHHCCEEEECCCCCEEE
FIKVVK
EEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]