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The map label for this gene is nrdR [H]

Identifier: 28199620

GI number: 28199620

Start: 2035131

End: 2035664

Strand: Reverse

Name: nrdR [H]

Synonym: PD1748

Alternate gene names: 28199620

Gene position: 2035664-2035131 (Counterclockwise)

Preceding gene: 28199621

Following gene: 28199619

Centisome position: 80.79

GC content: 53.37

Gene sequence:

>534_bases
ATGTATTGTCTGTTTTGCCAACATACCGATACCCGAGTGATTGATTCGCGCGTCTCCGAAGACGGTGCGACAATCCGGCG
TCGCCGCGAGTGTGAGGCGTGCGGTGAGCGTTTCAGTACGTTGGAAACGATTGAGTTGAAGTTGCCGGTGATCATCAAGA
AGGATGGTGGGCGTGAGGCATTTGATGGACGCAAGCTGCGTACCAGTTTTGATCGAGCTCTACAGAAGCGTCCAGTGGCT
GAGGAGCGCATTGAGATGGCGATGCGTGCGGTGATCCACCGTCTGCGTATGGCCGGTGAGCGTGAAGTGCCTTCAATCGT
GGTGGGTGAATGTGTTATGGCTGAGTTGCGTAAGCTCGACCATGTGGGCTATGTGCGTTTTGCTTCGGTCTATCGCAGTT
TCCAGGATGTTGCCGATTTCCGCGAAGAGATCGAAAAGCTTGAGAGCGAGTTACTGGTGAGTAGGGAGCAGTTGCCGTTG
TTGGAAGCAGTAATGGAATCGATAGGACACCCTTCTATTGATCAGGGGGGGTAA

Upstream 100 bases:

>100_bases
ATTGTGGCTACGTTTCGTATCGCAGCGGCGGTCAGAGCAATGCAACGTGGTTGACCGTATCAATCCCACTTAGTGTTGGC
CGACGAGTAGACTTGCGTGT

Downstream 100 bases:

>100_bases
GCACGGTGCGTGATGCACGTCATCACTGTTTTCTATGTGTTGCGATTGTTTGTTGATGGGGTTGCATCGGTATTTGGGTG
GCTGCGTTAATGAGTTCGGT

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MYCLFCQHTDTRVIDSRVSEDGATIRRRRECEACGERFSTLETIELKLPVIIKKDGGREAFDGRKLRTSFDRALQKRPVA
EERIEMAMRAVIHRLRMAGEREVPSIVVGECVMAELRKLDHVGYVRFASVYRSFQDVADFREEIEKLESELLVSREQLPL
LEAVMESIGHPSIDQGG

Sequences:

>Translated_177_residues
MYCLFCQHTDTRVIDSRVSEDGATIRRRRECEACGERFSTLETIELKLPVIIKKDGGREAFDGRKLRTSFDRALQKRPVA
EERIEMAMRAVIHRLRMAGEREVPSIVVGECVMAELRKLDHVGYVRFASVYRSFQDVADFREEIEKLESELLVSREQLPL
LEAVMESIGHPSIDQGG
>Mature_177_residues
MYCLFCQHTDTRVIDSRVSEDGATIRRRRECEACGERFSTLETIELKLPVIIKKDGGREAFDGRKLRTSFDRALQKRPVA
EERIEMAMRAVIHRLRMAGEREVPSIVVGECVMAELRKLDHVGYVRFASVYRSFQDVADFREEIEKLESELLVSREQLPL
LEAVMESIGHPSIDQGG

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes [H]

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain [H]

Homologues:

Organism=Escherichia coli, GI1786615, Length=148, Percent_Identity=52.027027027027, Blast_Score=164, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003796 [H]

Pfam domain/function: PF03477 ATP-cone [H]

EC number: NA

Molecular weight: Translated: 20315; Mature: 20315

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYCLFCQHTDTRVIDSRVSEDGATIRRRRECEACGERFSTLETIELKLPVIIKKDGGREA
CEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCC
FDGRKLRTSFDRALQKRPVAEERIEMAMRAVIHRLRMAGEREVPSIVVGECVMAELRKLD
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
HVGYVRFASVYRSFQDVADFREEIEKLESELLVSREQLPLLEAVMESIGHPSIDQGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MYCLFCQHTDTRVIDSRVSEDGATIRRRRECEACGERFSTLETIELKLPVIIKKDGGREA
CEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCC
FDGRKLRTSFDRALQKRPVAEERIEMAMRAVIHRLRMAGEREVPSIVVGECVMAELRKLD
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
HVGYVRFASVYRSFQDVADFREEIEKLESELLVSREQLPLLEAVMESIGHPSIDQGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]