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The map label for this gene is 28199216

Identifier: 28199216

GI number: 28199216

Start: 1560065

End: 1560448

Strand: Reverse

Name: 28199216

Synonym: PD1332

Alternate gene names: NA

Gene position: 1560448-1560065 (Counterclockwise)

Preceding gene: 28199217

Following gene: 28199214

Centisome position: 61.93

GC content: 39.06

Gene sequence:

>384_bases
ATGATAAGTTGCATTGATCATATTGTTATCACCACTAGGGATATCAAAGTATGCTCTGATTTTTATACTCGTATACTGGG
AATGGAGCTGATCCAGTTTGGTGATAACAGAATCGCGTTCAAGTTTGGACAACAAAAAATAAACGTTCACGAATATGGTA
AAGAGATAGAGCCTAAAGCGCATCTTCCTGTTCCTGGTTCCCTGGATATCTGCCTGATAAGTTCTTACTCAATTGATGAG
ATAAAGAAGGTTTTAGAAAAAAACGACATTGTGATTGTCGATGGTCCGGTATCCCGGACGGGGGCGTGCGGTGCTATAAC
TTCACTATATCTGCGTGATCCTGACCTTAATCTTATAGAAATCTCGAATTATGAAAATCACTAA

Upstream 100 bases:

>100_bases
GAAATTTCCGTCAACAGAATGTTTAGATTAGAAGCTAACTGGCGAAAATACTGTTCGCCATTTAGTGTAGCAAGTGATTT
TATTAAACAAGGGGTTGTAA

Downstream 100 bases:

>100_bases
CCGCTGGTGATAATGTCCGCGCTGTTAGGGGGTTGACGCTCAGTGGAACGAAAACGGTTCTGTCGCATTAAGGCCGCGTC
GGGTAGCATCGCAAAAAGAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 127; Mature: 127

Protein sequence:

>127_residues
MISCIDHIVITTRDIKVCSDFYTRILGMELIQFGDNRIAFKFGQQKINVHEYGKEIEPKAHLPVPGSLDICLISSYSIDE
IKKVLEKNDIVIVDGPVSRTGACGAITSLYLRDPDLNLIEISNYENH

Sequences:

>Translated_127_residues
MISCIDHIVITTRDIKVCSDFYTRILGMELIQFGDNRIAFKFGQQKINVHEYGKEIEPKAHLPVPGSLDICLISSYSIDE
IKKVLEKNDIVIVDGPVSRTGACGAITSLYLRDPDLNLIEISNYENH
>Mature_127_residues
MISCIDHIVITTRDIKVCSDFYTRILGMELIQFGDNRIAFKFGQQKINVHEYGKEIEPKAHLPVPGSLDICLISSYSIDE
IKKVLEKNDIVIVDGPVSRTGACGAITSLYLRDPDLNLIEISNYENH

Specific function: Is critically involved in promoting the replication of S.typhimurium cells inside host macrophages, suggesting a role in the establishment of bacterial colonization within macrophages. May be involved in the biosynthesis and modification of the peptidogly

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI254039722, Length=124, Percent_Identity=55.6451612903226, Blast_Score=144, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: NA

Molecular weight: Translated: 14296; Mature: 14296

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISCIDHIVITTRDIKVCSDFYTRILGMELIQFGDNRIAFKFGQQKINVHEYGKEIEPKA
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEECHHHCCCCCCCCC
HLPVPGSLDICLISSYSIDEIKKVLEKNDIVIVDGPVSRTGACGAITSLYLRDPDLNLIE
CCCCCCCCCEEEEECCCHHHHHHHHCCCCEEEECCCCCCCCCCHHHEEEEEECCCCCEEE
ISNYENH
ECCCCCC
>Mature Secondary Structure
MISCIDHIVITTRDIKVCSDFYTRILGMELIQFGDNRIAFKFGQQKINVHEYGKEIEPKA
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEECHHHCCCCCCCCC
HLPVPGSLDICLISSYSIDEIKKVLEKNDIVIVDGPVSRTGACGAITSLYLRDPDLNLIE
CCCCCCCCCEEEEECCCHHHHHHHHCCCCEEEECCCCCCCCCCHHHEEEEEECCCCCEEE
ISNYENH
ECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]