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The map label for this gene is dpm1 [H]

Identifier: 28199199

GI number: 28199199

Start: 1540730

End: 1541452

Strand: Reverse

Name: dpm1 [H]

Synonym: PD1313

Alternate gene names: 28199199

Gene position: 1541452-1540730 (Counterclockwise)

Preceding gene: 28199200

Following gene: 28199198

Centisome position: 61.17

GC content: 52.01

Gene sequence:

>723_bases
ATGACTGATTTGCAGCTTTCAGTTGTTGTTCCTGTGTTCAATGAGCGTGATAATGTCGCCCCCCTGATTGCAGAGATCGT
GGGTGTGTTGCGTGGGGTGAGGGTGTTCGAAATTGTTTATGTTGATGACAATTCGAAAGACGACACGCTCTCTGTGTTGC
GGGCGTTGAAGCTCTCCACTCCGGAACTACGCGTGTTTCACCATGCGGTTCGAGCGGGACAAAGTACGGGGATACGCAAT
GGTGTCAAAGCTGCGCGTGCGCCTTGGGTGGTCACTCTGGATGGTGACGGCCAGAATGATCCGTCCGATATCCTCAAACT
GTTGGCTGCACGTGAAGCAGCGGAACCATCGGTGAAACTATTCAACGGCTGGCGTGTGTATCGTCAAGATACAGTTTCAA
AGCGCTGGGCGAGCAAATGGGCAAATACGATCAGGGCACGTGTGCTGCGCGATGACACCCCTGATACTGCTTGCGGTATC
AAACTGTTTGAGCGTGCAGTGTTCTTAGAACTCCCGCACTTCGATCATATGCATCGTTTCTTGCCAGTGCTGATGCAGCG
TGCTGGTTGGAAAACGGCGAATGTGCCGGTGAATCATCGTTCTCGTGTCTCTGGAGTGTCCAAGTACAACAATCTTAATC
GTGCTTTAGTCGGCATCCGTGACTTGTATGGCGTGGCATGGTTGATAGCGCGTAGCATGTGTATCGACGCGCGTGAGTAT
TGA

Upstream 100 bases:

>100_bases
TCGGTATGCCGCAAGTGGTGGAGTGGTGCCGTCACTACTTTGATACCCGTGCCTCAACGTAATGCTTTTTGATCGTAATA
GTTGTTGCGATGGATAACCC

Downstream 100 bases:

>100_bases
GATCTGGAGACGATGGATTGAACGCACAGTTGCAATGGCTGTATTGGACAGGACTTCATATCACCTATTGGAAACTGATT
GGTTATAGCGGTGCGTTGCT

Product: dolichol-phosphate mannosyltransferase

Products: NA

Alternate protein names: Undecaprenyl-phosphate Ara4FN transferase; Ara4FN transferase [H]

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MTDLQLSVVVPVFNERDNVAPLIAEIVGVLRGVRVFEIVYVDDNSKDDTLSVLRALKLSTPELRVFHHAVRAGQSTGIRN
GVKAARAPWVVTLDGDGQNDPSDILKLLAAREAAEPSVKLFNGWRVYRQDTVSKRWASKWANTIRARVLRDDTPDTACGI
KLFERAVFLELPHFDHMHRFLPVLMQRAGWKTANVPVNHRSRVSGVSKYNNLNRALVGIRDLYGVAWLIARSMCIDAREY

Sequences:

>Translated_240_residues
MTDLQLSVVVPVFNERDNVAPLIAEIVGVLRGVRVFEIVYVDDNSKDDTLSVLRALKLSTPELRVFHHAVRAGQSTGIRN
GVKAARAPWVVTLDGDGQNDPSDILKLLAAREAAEPSVKLFNGWRVYRQDTVSKRWASKWANTIRARVLRDDTPDTACGI
KLFERAVFLELPHFDHMHRFLPVLMQRAGWKTANVPVNHRSRVSGVSKYNNLNRALVGIRDLYGVAWLIARSMCIDAREY
>Mature_239_residues
TDLQLSVVVPVFNERDNVAPLIAEIVGVLRGVRVFEIVYVDDNSKDDTLSVLRALKLSTPELRVFHHAVRAGQSTGIRNG
VKAARAPWVVTLDGDGQNDPSDILKLLAAREAAEPSVKLFNGWRVYRQDTVSKRWASKWANTIRARVLRDDTPDTACGIK
LFERAVFLELPHFDHMHRFLPVLMQRAGWKTANVPVNHRSRVSGVSKYNNLNRALVGIRDLYGVAWLIARSMCIDAREY

Specific function: Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides [H]

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788588, Length=208, Percent_Identity=26.9230769230769, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1788692, Length=222, Percent_Identity=25.6756756756757, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022857
- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: =2.7.8.30 [H]

Molecular weight: Translated: 27054; Mature: 26923

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLQLSVVVPVFNERDNVAPLIAEIVGVLRGVRVFEIVYVDDNSKDDTLSVLRALKLST
CCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHCCC
PELRVFHHAVRAGQSTGIRNGVKAARAPWVVTLDGDGQNDPSDILKLLAAREAAEPSVKL
CHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEE
FNGWRVYRQDTVSKRWASKWANTIRARVLRDDTPDTACGIKLFERAVFLELPHFDHMHRF
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
LPVLMQRAGWKTANVPVNHRSRVSGVSKYNNLNRALVGIRDLYGVAWLIARSMCIDAREY
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TDLQLSVVVPVFNERDNVAPLIAEIVGVLRGVRVFEIVYVDDNSKDDTLSVLRALKLST
CCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHCCC
PELRVFHHAVRAGQSTGIRNGVKAARAPWVVTLDGDGQNDPSDILKLLAAREAAEPSVKL
CHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEE
FNGWRVYRQDTVSKRWASKWANTIRARVLRDDTPDTACGIKLFERAVFLELPHFDHMHRF
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
LPVLMQRAGWKTANVPVNHRSRVSGVSKYNNLNRALVGIRDLYGVAWLIARSMCIDAREY
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12219091 [H]