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The map label for this gene is dnaQ [H]

Identifier: 28199104

GI number: 28199104

Start: 1418214

End: 1418933

Strand: Reverse

Name: dnaQ [H]

Synonym: PD1217

Alternate gene names: 28199104

Gene position: 1418933-1418214 (Counterclockwise)

Preceding gene: 28199105

Following gene: 28199102

Centisome position: 56.31

GC content: 51.39

Gene sequence:

>720_bases
ATGAGGAATAAGAAGCGTCAGATTGTTCTTGATACTGAGACCACTGGCCTGGAATGGAGCAAGGGGAACCGCATTGTGGA
GATCGGTGCGGTCGAACTGCTTGATCGCCGACTCAGTGGGGACAAATTTCATCGTTATCTCAAGCCTGATGTGTCGTTTG
AGTCCGGTGCCCAGGAGGTAACGGGGCTGACGATGGAGTTTCTAGCGGACAAGCCAGAGTTCAGCATGATTGCCGATAAG
TTTTTGGCTTATATCAATGGTGCCGAACTGATTATTCATAATGCGGCGTTCGATCTGGGATTCCTTGATTACGAGTTATC
GCGGTTGGGTTCGCAGTACGGGAAAATCACAGATCGTGCCAGCGTGCTTGACACTTTGGTGATGGCTCGGGAGCGTTATC
CGGGTCAGCGTAATTCACTGGATGCATTATGTAAGCGTCTTGGTGTGGATAACGCCCACCGTCAGTTACATGGTGCATTA
CTTGACGCGCAGATATTGGCCGATGTTTATATCGCGTTGACCTCTGGACAAGAGGAAATTGGTTTTGCATTGCCTGAGAG
CAGCCGTGGTGGTGTCGATGCCGCTAGCGTGGCATTTATGCCGGATGTGTTGTTAACACGTCCATGTGTGGTGGCGTCGC
AATCCGAACTGGAGGCGCATGAGGCGCGTTTGGCCAAGTTGCGTAAGATCGCTGGTCATGTGCTGTGGGATGCGATATAG

Upstream 100 bases:

>100_bases
GGTGTTGGGTCAAGGCTCACAATGGTGATTCGGATAATGAACGGGTTGATGTATTGGCCCGCGGCCAAGCGATGGCGCAG
CGTAGTACGGTAGCAAGTCG

Downstream 100 bases:

>100_bases
GTTTGGGTTTTTGTCGTTACTGGTCGAAATTGGAGGTATCTGTTTGGGTACTGGCTCTAGCCGATGACTTTCATACGTCA
GTGATAGCGAATTAGCACCA

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MRNKKRQIVLDTETTGLEWSKGNRIVEIGAVELLDRRLSGDKFHRYLKPDVSFESGAQEVTGLTMEFLADKPEFSMIADK
FLAYINGAELIIHNAAFDLGFLDYELSRLGSQYGKITDRASVLDTLVMARERYPGQRNSLDALCKRLGVDNAHRQLHGAL
LDAQILADVYIALTSGQEEIGFALPESSRGGVDAASVAFMPDVLLTRPCVVASQSELEAHEARLAKLRKIAGHVLWDAI

Sequences:

>Translated_239_residues
MRNKKRQIVLDTETTGLEWSKGNRIVEIGAVELLDRRLSGDKFHRYLKPDVSFESGAQEVTGLTMEFLADKPEFSMIADK
FLAYINGAELIIHNAAFDLGFLDYELSRLGSQYGKITDRASVLDTLVMARERYPGQRNSLDALCKRLGVDNAHRQLHGAL
LDAQILADVYIALTSGQEEIGFALPESSRGGVDAASVAFMPDVLLTRPCVVASQSELEAHEARLAKLRKIAGHVLWDAI
>Mature_239_residues
MRNKKRQIVLDTETTGLEWSKGNRIVEIGAVELLDRRLSGDKFHRYLKPDVSFESGAQEVTGLTMEFLADKPEFSMIADK
FLAYINGAELIIHNAAFDLGFLDYELSRLGSQYGKITDRASVLDTLVMARERYPGQRNSLDALCKRLGVDNAHRQLHGAL
LDAQILADVYIALTSGQEEIGFALPESSRGGVDAASVAFMPDVLLTRPCVVASQSELEAHEARLAKLRKIAGHVLWDAI

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=237, Percent_Identity=49.789029535865, Blast_Score=229, Evalue=1e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 26446; Mature: 26446

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNKKRQIVLDTETTGLEWSKGNRIVEIGAVELLDRRLSGDKFHRYLKPDVSFESGAQEV
CCCCCCEEEEECCCCCCEECCCCEEEEEHHHHHHHHHCCHHHHHHHCCCCCCCCCCHHHH
TGLTMEFLADKPEFSMIADKFLAYINGAELIIHNAAFDLGFLDYELSRLGSQYGKITDRA
HHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEECHHHCHHHHHHHHHHHHHHCCHHHHH
SVLDTLVMARERYPGQRNSLDALCKRLGVDNAHRQLHGALLDAQILADVYIALTSGQEEI
HHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEECCCHHH
GFALPESSRGGVDAASVAFMPDVLLTRPCVVASQSELEAHEARLAKLRKIAGHVLWDAI
CEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRNKKRQIVLDTETTGLEWSKGNRIVEIGAVELLDRRLSGDKFHRYLKPDVSFESGAQEV
CCCCCCEEEEECCCCCCEECCCCEEEEEHHHHHHHHHCCHHHHHHHCCCCCCCCCCHHHH
TGLTMEFLADKPEFSMIADKFLAYINGAELIIHNAAFDLGFLDYELSRLGSQYGKITDRA
HHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEECHHHCHHHHHHHHHHHHHHCCHHHHH
SVLDTLVMARERYPGQRNSLDALCKRLGVDNAHRQLHGALLDAQILADVYIALTSGQEEI
HHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEECCCHHH
GFALPESSRGGVDAASVAFMPDVLLTRPCVVASQSELEAHEARLAKLRKIAGHVLWDAI
CEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3023634; 6316347; 3540531; 9278503; 1575709 [H]