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The map label for this gene is ugd [H]

Identifier: 28199057

GI number: 28199057

Start: 1369481

End: 1370833

Strand: Reverse

Name: ugd [H]

Synonym: PD1167

Alternate gene names: 28199057

Gene position: 1370833-1369481 (Counterclockwise)

Preceding gene: 28199058

Following gene: 28199056

Centisome position: 54.4

GC content: 50.11

Gene sequence:

>1353_bases
ATGCGTGTTGCGATTTTCGGTACTGGTTATGTCGGTCTCGTTACAGGAACTTGCCTGGCTGAAGTCGGACATGAGGTGCT
TTGTGTTGATATCAACCAAGAAAAAGTTGATGGTCTCAATTGTGGGGTTATTCCTATTTATGAACCTGGGTTGGAACCGA
TGGTCAAGGCCAACCATGCCACCGGACGATTGCGTTTTACGACGGATTCGGTTGCGGCCATTGCTCATGGTGAAATTACT
TTTATCGCTGTCGGTACGCCTCCGGATGAAGATGGTGCTGCGGACTTGCAGTATGTGTTAGCGGTGGCACGTACCATCGG
TCAGTGCATTGATAGGCCGACGATTGTGGTCAATAAGTCCACAGTGCCAGTGGGGACTGCCGATCAGGTGCGTGCTGCCA
TCCAGCATGAGATGGATGTGCGTGGCGTGGACTTCAAGTTTGAGGTGGTTTCTAACCCAGAGTTTCTGAAGGAGGGTGAT
GCAGTTGCTGACTGTATGCGTCCGGATCGTATTGTGATCGGTGCCAGAAGTCGGGATGCAGTGGTTCGCATGCGTCGTCT
GTATGCGCCTTTTAACCGTAATCATGACCGTATTGTTGAGATGGATGTGCGTTCGGCCGAACTGACAAAATATGCGGCTA
ATGCAATGTTGGCCACTAAGATCAGTTTTATGAACGAAGTTGCCAACATTGCTGAGCATGTGGGTGCTGACATTGAATAT
GTGCGTAAAGGTATCGGTTCTGACCCACGCATCGGTTGGCACTTTATCTATCCTGGTGTTGGCTATGGTGGTTCGTGTTT
TCCCAAGGACGTCAAGGCGTTGGCACGTACTGCACAGCAATATGGTGTGGATCCGAAGCTGCTTAACGCGGTGGAAGATG
TTAATCATGCACAGAAGGGACATCTGTTTGAACTCATGCTGCGTCACTATGGATGTAGTGGTGAGAGCACGATGTTGGCT
GGGAAAACATTTGCAGTGTGGGGATTGGCATTCAAGCCTAATACCGATGATATGCGCGAGGCTCCCAGTTGCCGATTGTT
AGTGCAATTGTGGAAGGCAGGTGCTCAAGTGCGTGCTTATGATCCCGAGTCCATGCAGGAGGCGCGCAGGATATTCGGTG
AACGTGATGATCTGGTGTTTTGTGAGACCGCGTATGCGGCTTTGCAATGTGCTGATGCTTTGATTGTAGTGACTGAGTGG
AAGCAGTTTCGCAGCCCGGATTTTTTTGTTATTCGAGACGCTTTGAAAGACGCTGTGATCTTTGATGGTCGTAATCTTTA
TGATCCGCAGGAAATCGAAGAAGCAGGGTTGGCCTACTATGGGATCGGGCGGGGCCGTTCGTTGCATGCATGA

Upstream 100 bases:

>100_bases
GGACTCCGGGTGGTCCGATTGGTCCTGATGCAACGTTGACCTTTGACGTGGAGCTGCTCAGTATCCTCCCTTAATCCCCC
CCCCGTTTTAAGGAGTCATC

Downstream 100 bases:

>100_bases
AAAGCTACTGACACTGTGTGATTGTGCGTTTGAAGCCCGCCTAATTGAATTGGAGATGCGTGTTTCTTTCCAAGAACAAG
CGTTGACTGAAATAAGCGAA

Product: UDP-glucose dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MRVAIFGTGYVGLVTGTCLAEVGHEVLCVDINQEKVDGLNCGVIPIYEPGLEPMVKANHATGRLRFTTDSVAAIAHGEIT
FIAVGTPPDEDGAADLQYVLAVARTIGQCIDRPTIVVNKSTVPVGTADQVRAAIQHEMDVRGVDFKFEVVSNPEFLKEGD
AVADCMRPDRIVIGARSRDAVVRMRRLYAPFNRNHDRIVEMDVRSAELTKYAANAMLATKISFMNEVANIAEHVGADIEY
VRKGIGSDPRIGWHFIYPGVGYGGSCFPKDVKALARTAQQYGVDPKLLNAVEDVNHAQKGHLFELMLRHYGCSGESTMLA
GKTFAVWGLAFKPNTDDMREAPSCRLLVQLWKAGAQVRAYDPESMQEARRIFGERDDLVFCETAYAALQCADALIVVTEW
KQFRSPDFFVIRDALKDAVIFDGRNLYDPQEIEEAGLAYYGIGRGRSLHA

Sequences:

>Translated_450_residues
MRVAIFGTGYVGLVTGTCLAEVGHEVLCVDINQEKVDGLNCGVIPIYEPGLEPMVKANHATGRLRFTTDSVAAIAHGEIT
FIAVGTPPDEDGAADLQYVLAVARTIGQCIDRPTIVVNKSTVPVGTADQVRAAIQHEMDVRGVDFKFEVVSNPEFLKEGD
AVADCMRPDRIVIGARSRDAVVRMRRLYAPFNRNHDRIVEMDVRSAELTKYAANAMLATKISFMNEVANIAEHVGADIEY
VRKGIGSDPRIGWHFIYPGVGYGGSCFPKDVKALARTAQQYGVDPKLLNAVEDVNHAQKGHLFELMLRHYGCSGESTMLA
GKTFAVWGLAFKPNTDDMREAPSCRLLVQLWKAGAQVRAYDPESMQEARRIFGERDDLVFCETAYAALQCADALIVVTEW
KQFRSPDFFVIRDALKDAVIFDGRNLYDPQEIEEAGLAYYGIGRGRSLHA
>Mature_450_residues
MRVAIFGTGYVGLVTGTCLAEVGHEVLCVDINQEKVDGLNCGVIPIYEPGLEPMVKANHATGRLRFTTDSVAAIAHGEIT
FIAVGTPPDEDGAADLQYVLAVARTIGQCIDRPTIVVNKSTVPVGTADQVRAAIQHEMDVRGVDFKFEVVSNPEFLKEGD
AVADCMRPDRIVIGARSRDAVVRMRRLYAPFNRNHDRIVEMDVRSAELTKYAANAMLATKISFMNEVANIAEHVGADIEY
VRKGIGSDPRIGWHFIYPGVGYGGSCFPKDVKALARTAQQYGVDPKLLNAVEDVNHAQKGHLFELMLRHYGCSGESTMLA
GKTFAVWGLAFKPNTDDMREAPSCRLLVQLWKAGAQVRAYDPESMQEARRIFGERDDLVFCETAYAALQCADALIVVTEW
KQFRSPDFFVIRDALKDAVIFDGRNLYDPQEIEEAGLAYYGIGRGRSLHA

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=475, Percent_Identity=33.0526315789474, Blast_Score=221, Evalue=2e-57,
Organism=Homo sapiens, GI296040438, Length=377, Percent_Identity=33.1564986737401, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI296040443, Length=331, Percent_Identity=32.3262839879154, Blast_Score=149, Evalue=5e-36,
Organism=Escherichia coli, GI1788340, Length=364, Percent_Identity=29.1208791208791, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI48994968, Length=416, Percent_Identity=29.3269230769231, Blast_Score=140, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17560350, Length=475, Percent_Identity=35.1578947368421, Blast_Score=245, Evalue=3e-65,
Organism=Drosophila melanogaster, GI17136908, Length=472, Percent_Identity=32.4152542372881, Blast_Score=221, Evalue=9e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 49566; Mature: 49566

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVAIFGTGYVGLVTGTCLAEVGHEVLCVDINQEKVDGLNCGVIPIYEPGLEPMVKANHA
CEEEEEECCHHHHHHHHHHHHCCCEEEEEECCHHHCCCCCCCEEEEECCCCCHHHCCCCC
TGRLRFTTDSVAAIAHGEITFIAVGTPPDEDGAADLQYVLAVARTIGQCIDRPTIVVNKS
CCEEEEECCCEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECC
TVPVGTADQVRAAIQHEMDVRGVDFKFEVVSNPEFLKEGDAVADCMRPDRIVIGARSRDA
CCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHCCCHHHHHCCCCEEEEECCCHHH
VVRMRRLYAPFNRNHDRIVEMDVRSAELTKYAANAMLATKISFMNEVANIAEHVGADIEY
HHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRKGIGSDPRIGWHFIYPGVGYGGSCFPKDVKALARTAQQYGVDPKLLNAVEDVNHAQKG
HHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
HLFELMLRHYGCSGESTMLAGKTFAVWGLAFKPNTDDMREAPSCRLLVQLWKAGAQVRAY
HHHHHHHHHHCCCCCCEEEECCEEEEEEEEECCCCCHHHCCCHHHHHHHHHHCCCEEEEC
DPESMQEARRIFGERDDLVFCETAYAALQCADALIVVTEWKQFRSPDFFVIRDALKDAVI
CCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCEEEEEEEHHHHCCCCEEEEHHHHHHHEE
FDGRNLYDPQEIEEAGLAYYGIGRGRSLHA
ECCCCCCCHHHHHHCCCEEEECCCCCCCCC
>Mature Secondary Structure
MRVAIFGTGYVGLVTGTCLAEVGHEVLCVDINQEKVDGLNCGVIPIYEPGLEPMVKANHA
CEEEEEECCHHHHHHHHHHHHCCCEEEEEECCHHHCCCCCCCEEEEECCCCCHHHCCCCC
TGRLRFTTDSVAAIAHGEITFIAVGTPPDEDGAADLQYVLAVARTIGQCIDRPTIVVNKS
CCEEEEECCCEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECC
TVPVGTADQVRAAIQHEMDVRGVDFKFEVVSNPEFLKEGDAVADCMRPDRIVIGARSRDA
CCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHCCCHHHHHCCCCEEEEECCCHHH
VVRMRRLYAPFNRNHDRIVEMDVRSAELTKYAANAMLATKISFMNEVANIAEHVGADIEY
HHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRKGIGSDPRIGWHFIYPGVGYGGSCFPKDVKALARTAQQYGVDPKLLNAVEDVNHAQKG
HHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
HLFELMLRHYGCSGESTMLAGKTFAVWGLAFKPNTDDMREAPSCRLLVQLWKAGAQVRAY
HHHHHHHHHHCCCCCCEEEECCEEEEEEEEECCCCCHHHCCCHHHHHHHHHHCCCEEEEC
DPESMQEARRIFGERDDLVFCETAYAALQCADALIVVTEWKQFRSPDFFVIRDALKDAVI
CCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCEEEEEEEHHHHCCCCEEEEHHHHHHHEE
FDGRNLYDPQEIEEAGLAYYGIGRGRSLHA
ECCCCCCCHHHHHHCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]