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The map label for this gene is lytH

Identifier: 255767742

GI number: 255767742

Start: 3321455

End: 3322435

Strand: Direct

Name: lytH

Synonym: BSU32340

Alternate gene names: 255767742

Gene position: 3321455-3322435 (Clockwise)

Preceding gene: 16080285

Following gene: 16080295

Centisome position: 78.79

GC content: 48.73

Gene sequence:

>981_bases
GTGAAAGTTTTGTTATCCGCTCTTCTTCTCCTTTTGTTTGCATTTGAGCCTTCTGCGTCTGGAAAAAAACTTTCAGATCC
AGTGCTGTCGAAACGGATGGAATTATATCATAAAATCGAAGCTGTGACGCAGATCCCTTGGTATGCGCTCGCCGCTGTTG
ATCAATACGAAGAAAACGTGCGGAGCAACCGGAAAGATCTGCCTGAAAAGGCGGGAATCATCAGCATCTATATACCCGAT
GATATCTGGAGCGGGCCTGAAAACCCGAATCCGAAAGACGATGCGCCGTTAAGCATTAAAGTGTTTGACGGAATCGGAAT
GGATGGCGATGGAGACGGGAAAGCCGAGGTCAGCAACGATGAAGATATCTTGTATACGTTCAGCCAATACTTACTGTCGT
ATGGCACAGATGAAGACAACATCCGGATCGGGCTTTGGAATTATTACCGGCGTGATCAGACAGTGGGGATTATATCTGAA
TTCATGAAGCTGTTTAAAGCCTACGGCCATATTGATCTGGGCGAGCATGCATTCCCGCTTCCGATCAGAACCGATTACAG
CTACCGAAGCACGTGGGGAGATGCCCGCGGCTTCGGTGGAAGGCGGATTCATGAAGGTACGGATATCTTTGCCCATTACG
GCCTTCCTGTCAAATCCACATGTTACGGCGTAGTTGAAATGAAGGGCTGGAACCGCTTCGGAGGATGGAGAATCGGCATC
AGGGACATTAACAATACGTATCATTATTTTGCCCATCTCAATGGGTTTGCCAAAGGGATTAAAACAGGACAAATCGTTGA
GCCTGGCCAAGTGATCGGATCAGTCGGCAGCTCCGGATACGGCCCGCCGGGAACCGCCGGGAAGTTCCCGCCGCATCTGC
ACTATGGCATGTACAAAGATAACGGAAGAACCGAATGGTCATTTGATCCATACCCGCATTTGAGGGCGTGGGAGCGATAT
GAATACCAAAAAAAGAAGTAA

Upstream 100 bases:

>100_bases
TAACATAGGAAAAATTTCTCGACAAGGGAAGATGATTACTGACATTTTTAAGCCGGGTTGCCGCAAACTATGTGTATTCA
ATATGAAAGGAGATTATTTT

Downstream 100 bases:

>100_bases
CAAAAAGCCGCCTCTTCAACAGGCGGCTTATTTGCTGCTTTTTTCTTTTTTTGAATCGGCACCGTTTTCTTTGCTGCTCG
GAAGCTGGACAGAAGGCGTG

Product: sporulation-specific L-Ala-D-Glu endopeptidase

Products: NA

Alternate protein names: Peptidoglycan hydrolase; Sporulation-specific endopeptidase

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MKVLLSALLLLLFAFEPSASGKKLSDPVLSKRMELYHKIEAVTQIPWYALAAVDQYEENVRSNRKDLPEKAGIISIYIPD
DIWSGPENPNPKDDAPLSIKVFDGIGMDGDGDGKAEVSNDEDILYTFSQYLLSYGTDEDNIRIGLWNYYRRDQTVGIISE
FMKLFKAYGHIDLGEHAFPLPIRTDYSYRSTWGDARGFGGRRIHEGTDIFAHYGLPVKSTCYGVVEMKGWNRFGGWRIGI
RDINNTYHYFAHLNGFAKGIKTGQIVEPGQVIGSVGSSGYGPPGTAGKFPPHLHYGMYKDNGRTEWSFDPYPHLRAWERY
EYQKKK

Sequences:

>Translated_326_residues
MKVLLSALLLLLFAFEPSASGKKLSDPVLSKRMELYHKIEAVTQIPWYALAAVDQYEENVRSNRKDLPEKAGIISIYIPD
DIWSGPENPNPKDDAPLSIKVFDGIGMDGDGDGKAEVSNDEDILYTFSQYLLSYGTDEDNIRIGLWNYYRRDQTVGIISE
FMKLFKAYGHIDLGEHAFPLPIRTDYSYRSTWGDARGFGGRRIHEGTDIFAHYGLPVKSTCYGVVEMKGWNRFGGWRIGI
RDINNTYHYFAHLNGFAKGIKTGQIVEPGQVIGSVGSSGYGPPGTAGKFPPHLHYGMYKDNGRTEWSFDPYPHLRAWERY
EYQKKK
>Mature_326_residues
MKVLLSALLLLLFAFEPSASGKKLSDPVLSKRMELYHKIEAVTQIPWYALAAVDQYEENVRSNRKDLPEKAGIISIYIPD
DIWSGPENPNPKDDAPLSIKVFDGIGMDGDGDGKAEVSNDEDILYTFSQYLLSYGTDEDNIRIGLWNYYRRDQTVGIISE
FMKLFKAYGHIDLGEHAFPLPIRTDYSYRSTWGDARGFGGRRIHEGTDIFAHYGLPVKSTCYGVVEMKGWNRFGGWRIGI
RDINNTYHYFAHLNGFAKGIKTGQIVEPGQVIGSVGSSGYGPPGTAGKFPPHLHYGMYKDNGRTEWSFDPYPHLRAWERY
EYQKKK

Specific function: L-Ala--D-Glu endopeptidase involved in production of single L-alanine side chains from tetrapeptides in the spore cortex peptidoglycan. Therefore, is required for the endospore cortex maturation

COG id: COG0739

COG function: function code M; Membrane proteins related to metalloendopeptidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M23B family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LYTH_BACSU (O32130)

Other databases:

- EMBL:   AL009126
- PIR:   D70015
- RefSeq:   NP_391114.2
- ProteinModelPortal:   O32130
- SMR:   O32130
- EnsemblBacteria:   EBBACT00000001126
- GeneID:   936510
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU32340
- NMPDR:   fig|224308.1.peg.3240
- GenoList:   BSU32340
- GeneTree:   EBGT00050000000341
- HOGENOM:   HBG313818
- ProtClustDB:   CLSK873616
- BioCyc:   BSUB:BSU32340-MONOMER
- InterPro:   IPR011055
- InterPro:   IPR016047

Pfam domain/function: PF01551 Peptidase_M23; SSF51261 Dup_hybrid_motif

EC number: NA

Molecular weight: Translated: 36957; Mature: 36957

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLLSALLLLLFAFEPSASGKKLSDPVLSKRMELYHKIEAVTQIPWYALAAVDQYEENV
CHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
RSNRKDLPEKAGIISIYIPDDIWSGPENPNPKDDAPLSIKVFDGIGMDGDGDGKAEVSND
HHHHHCCHHHCCEEEEEECCHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCC
EDILYTFSQYLLSYGTDEDNIRIGLWNYYRRDQTVGIISEFMKLFKAYGHIDLGEHAFPL
CHHHHHHHHHHHHCCCCCCCEEEEEEHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
PIRTDYSYRSTWGDARGFGGRRIHEGTDIFAHYGLPVKSTCYGVVEMKGWNRFGGWRIGI
EECCCCCHHHCCCCCCCCCCCEECCCCEEEEECCCCCCHHEEEEEEECCCCCCCCEEEEE
RDINNTYHYFAHLNGFAKGIKTGQIVEPGQVIGSVGSSGYGPPGTAGKFPPHLHYGMYKD
EECCCCEEEHHHHHHHHHCCCCCCEECHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEC
NGRTEWSFDPYPHLRAWERYEYQKKK
CCCCCCCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MKVLLSALLLLLFAFEPSASGKKLSDPVLSKRMELYHKIEAVTQIPWYALAAVDQYEENV
CHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
RSNRKDLPEKAGIISIYIPDDIWSGPENPNPKDDAPLSIKVFDGIGMDGDGDGKAEVSND
HHHHHCCHHHCCEEEEEECCHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCC
EDILYTFSQYLLSYGTDEDNIRIGLWNYYRRDQTVGIISEFMKLFKAYGHIDLGEHAFPL
CHHHHHHHHHHHHCCCCCCCEEEEEEHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
PIRTDYSYRSTWGDARGFGGRRIHEGTDIFAHYGLPVKSTCYGVVEMKGWNRFGGWRIGI
EECCCCCHHHCCCCCCCCCCCEECCCCEEEEECCCCCCHHEEEEEEECCCCCCCCEEEEE
RDINNTYHYFAHLNGFAKGIKTGQIVEPGQVIGSVGSSGYGPPGTAGKFPPHLHYGMYKD
EECCCCEEEHHHHHHHHHCCCCCCEECHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEC
NGRTEWSFDPYPHLRAWERYEYQKKK
CCCCCCCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12813075