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The map label for this gene is nusG [H]

Identifier: 239618207

GI number: 239618207

Start: 1976618

End: 1977682

Strand: Reverse

Name: nusG [H]

Synonym: Kole_1843

Alternate gene names: 239618207

Gene position: 1977682-1976618 (Counterclockwise)

Preceding gene: 239618208

Following gene: 239618206

Centisome position: 85.91

GC content: 43.29

Gene sequence:

>1065_bases
GTGCGTAAAAAGTGGTACATAATTCAAACTTATTCCGGACTTGAAAATTCTATTAAGGAAGCTCTGGAAGCAAAAGTTCG
CTCCTATGGTTATGATCATCTTTTCGGCAGAATCCTTGTCCCGGAAGAGGTAAAGCTTGACAGAACCTCCGCGGCGGCGG
AGAAGCATATTGTCTCATCTGACGCCGAGCTTCTTGTATCATCTAACCAGGATGTCAAGAAGGGTGATCCCATTGCCAGA
GAGCCAGAAGCAAAAGCGAAAAACGACGGTGTAATAAAAGAGATCAAGAATTACCGGGTGATCTTCATAGAAACAATAGA
CAGGCGTTATACTAAAACCTATTACATTCCTGAAAGCGCAAAAGTCGAAACAGGGATTAAGGCCGGTGCACGAATTCGTC
AGGGAATGCCTCTGGCGAAGCAGGGAGATTTTTTCTGTGAGCTTGATGGTAGAATCGTCTTCACCGAAAAGATGAAACGT
ATCGTAGTTGAAAAAGATAACGGCGGAGAAGACGTCTACATGGTCTATCCGAAGAGCTATGATCCGAAGATCATCAAAAA
AGGCGCCAAAGTCAGCCGCGGACAGAAAATAGCCGATTCGAAAACCATATATTCCAAGATTGATGGGCGTACAGAGATCG
CTGAACTACCCGGTAGAAAAGAGATCAAGATCTTTAAAATCACCCGCACAAGGCTTTACCCGGGATATATCTTTATCGAG
ATGATCATGACTGACGAGACGTGGAATCTCGTCAAGAGTACACCTAATGTTGTCAACTTCGTCTCAAATGGCGGACAGCC
CATAGAACTAAAGCCCAAAGAGATCAAGGCGCTGTTAAGATTGGTTGGGCTCGAGGAATACGAAGAAAAAACTAGACCAA
TCAAGGTTGAGGTTGATTTTGAAGTCAACGAAATGGTTCGTATAAATTCTGGACCTTTTGAAGACTTCGTAGGTAAAATC
ACAGAGATTGATCCTGAAAGACAGGAAGTTAAAGTCGTTGTCAGCATATTCGGCCGTGAAACACCAGTTATGCTAAACCT
GTCAGAGATAGAAAAAATTGTTTGA

Upstream 100 bases:

>100_bases
TTCTCGGACTTCTCGATATTATTTTTACTAATGTCATAGGCGACCTTCTTAAGTTCCTCACAGGTGGCCTATAATAATGA
ATACCGCAAGGTGATATCTG

Downstream 100 bases:

>100_bases
AGCATTTTGAAGCATCACGATAAATACGTGGGAGGGAATATCCCGCTAAAACCACAGGAGGTAGTGAAATATGGCTAAGA
AGATTATTGCAAAAATCAAG

Product: NusG antitermination factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MRKKWYIIQTYSGLENSIKEALEAKVRSYGYDHLFGRILVPEEVKLDRTSAAAEKHIVSSDAELLVSSNQDVKKGDPIAR
EPEAKAKNDGVIKEIKNYRVIFIETIDRRYTKTYYIPESAKVETGIKAGARIRQGMPLAKQGDFFCELDGRIVFTEKMKR
IVVEKDNGGEDVYMVYPKSYDPKIIKKGAKVSRGQKIADSKTIYSKIDGRTEIAELPGRKEIKIFKITRTRLYPGYIFIE
MIMTDETWNLVKSTPNVVNFVSNGGQPIELKPKEIKALLRLVGLEEYEEKTRPIKVEVDFEVNEMVRINSGPFEDFVGKI
TEIDPERQEVKVVVSIFGRETPVMLNLSEIEKIV

Sequences:

>Translated_354_residues
MRKKWYIIQTYSGLENSIKEALEAKVRSYGYDHLFGRILVPEEVKLDRTSAAAEKHIVSSDAELLVSSNQDVKKGDPIAR
EPEAKAKNDGVIKEIKNYRVIFIETIDRRYTKTYYIPESAKVETGIKAGARIRQGMPLAKQGDFFCELDGRIVFTEKMKR
IVVEKDNGGEDVYMVYPKSYDPKIIKKGAKVSRGQKIADSKTIYSKIDGRTEIAELPGRKEIKIFKITRTRLYPGYIFIE
MIMTDETWNLVKSTPNVVNFVSNGGQPIELKPKEIKALLRLVGLEEYEEKTRPIKVEVDFEVNEMVRINSGPFEDFVGKI
TEIDPERQEVKVVVSIFGRETPVMLNLSEIEKIV
>Mature_354_residues
MRKKWYIIQTYSGLENSIKEALEAKVRSYGYDHLFGRILVPEEVKLDRTSAAAEKHIVSSDAELLVSSNQDVKKGDPIAR
EPEAKAKNDGVIKEIKNYRVIFIETIDRRYTKTYYIPESAKVETGIKAGARIRQGMPLAKQGDFFCELDGRIVFTEKMKR
IVVEKDNGGEDVYMVYPKSYDPKIIKKGAKVSRGQKIADSKTIYSKIDGRTEIAELPGRKEIKIFKITRTRLYPGYIFIE
MIMTDETWNLVKSTPNVVNFVSNGGQPIELKPKEIKALLRLVGLEEYEEKTRPIKVEVDFEVNEMVRINSGPFEDFVGKI
TEIDPERQEVKVVVSIFGRETPVMLNLSEIEKIV

Specific function: Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase [H]

COG id: COG0250

COG function: function code K; Transcription antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KOW domain [H]

Homologues:

Organism=Escherichia coli, GI1790414, Length=123, Percent_Identity=42.2764227642276, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005824
- InterPro:   IPR001062
- InterPro:   IPR015869
- InterPro:   IPR006645
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF00467 KOW; PF02357 NusG [H]

EC number: NA

Molecular weight: Translated: 40481; Mature: 40481

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS01014 NUSG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKKWYIIQTYSGLENSIKEALEAKVRSYGYDHLFGRILVPEEVKLDRTSAAAEKHIVSS
CCCEEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHCEEECCCCCCCCCHHHHHHHHHHCC
DAELLVSSNQDVKKGDPIAREPEAKAKNDGVIKEIKNYRVIFIETIDRRYTKTYYIPESA
CCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEEECCCCEEEEEECCCCC
KVETGIKAGARIRQGMPLAKQGDFFCELDGRIVFTEKMKRIVVEKDNGGEDVYMVYPKSY
CCCCCHHHCHHHHCCCCCCCCCCEEEEECCEEEEECHHCEEEEECCCCCCEEEEECCCCC
DPKIIKKGAKVSRGQKIADSKTIYSKIDGRTEIAELPGRKEIKIFKITRTRLYPGYIFIE
CHHHHHCCCCCCCCCCCCCCHHHHHHCCCCHHHHHCCCCCCEEEEEEEECEECCCEEEEE
MIMTDETWNLVKSTPNVVNFVSNGGQPIELKPKEIKALLRLVGLEEYEEKTRPIKVEVDF
EEEECCCHHHHHCCCHHHHHHHCCCCEEEECHHHHHHHHHHHCCHHHHHCCCCEEEEEEC
EVNEMVRINSGPFEDFVGKITEIDPERQEVKVVVSIFGRETPVMLNLSEIEKIV
CCCEEEEECCCCHHHHHHHHHCCCCCHHHHEEEEEECCCCCCEEEEHHHHHHCC
>Mature Secondary Structure
MRKKWYIIQTYSGLENSIKEALEAKVRSYGYDHLFGRILVPEEVKLDRTSAAAEKHIVSS
CCCEEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHCEEECCCCCCCCCHHHHHHHHHHCC
DAELLVSSNQDVKKGDPIAREPEAKAKNDGVIKEIKNYRVIFIETIDRRYTKTYYIPESA
CCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEEECCCCEEEEEECCCCC
KVETGIKAGARIRQGMPLAKQGDFFCELDGRIVFTEKMKRIVVEKDNGGEDVYMVYPKSY
CCCCCHHHCHHHHCCCCCCCCCCEEEEECCEEEEECHHCEEEEECCCCCCEEEEECCCCC
DPKIIKKGAKVSRGQKIADSKTIYSKIDGRTEIAELPGRKEIKIFKITRTRLYPGYIFIE
CHHHHHCCCCCCCCCCCCCCHHHHHHCCCCHHHHHCCCCCCEEEEEEEECEECCCEEEEE
MIMTDETWNLVKSTPNVVNFVSNGGQPIELKPKEIKALLRLVGLEEYEEKTRPIKVEVDF
EEEECCCHHHHHCCCHHHHHHHCCCCEEEECHHHHHHHHHHHCCHHHHHCCCCEEEEEEC
EVNEMVRINSGPFEDFVGKITEIDPERQEVKVVVSIFGRETPVMLNLSEIEKIV
CCCEEEEECCCCHHHHHHHHHCCCCCHHHHEEEEEECCCCCCEEEEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1429627; 10360571 [H]