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The map label for this gene is ruvA

Identifier: 239618103

GI number: 239618103

Start: 1863087

End: 1863674

Strand: Reverse

Name: ruvA

Synonym: Kole_1735

Alternate gene names: 239618103

Gene position: 1863674-1863087 (Counterclockwise)

Preceding gene: 239618104

Following gene: 239618102

Centisome position: 80.95

GC content: 44.22

Gene sequence:

>588_bases
TTGATAAAAGGCGTTGAAGGAGAAATAACAGAGATATCCGGAAACGAGGTCACACTGAAGGCAGGACAGTTCTATCTGAA
CATTCTGTGTTCGACCAATACAATAAAGGAACTTTCACTGTCGGCAAAGGTTCATCTTTTGACGTACCTTTCTTTCTCAG
CCGACAGGGCCCCTGAAATATACGGCTTCAAAGACCGTGCGGAATATAACGTCTTTTTAATGCTGTTAAAAGCGAATAAG
ATAGGCCCAAAAATGGCTTTGAAAATTCTCTCTGCAACTTCTCCGGAAATGCTTCAGAAGATGATAGCGTCAAAAGACAT
TTCCGGGCTTTCCAGATTGCCAGGATTAGGTAAAAAAACCGCCGAAAGGCTGGTTAGTGAACTTTACGATCTCGTAAAAG
ACTATGCGGTAGAGTTCCCGAAAGAACTGAGTGACGTTTCTGAAGACGCGGTCGGCGCGCTGACCGCTCTGGGATTCGAT
ATGACAAGCGCCAAATTGGCTGTAAACGAGGTCCTGAAAGAGCAAACGGTAGAAAATACCCAGGAATTGGTAAGGAAAGC
TCTGAGAAAACTAAATAAGACCCGGTAA

Upstream 100 bases:

>100_bases
GAAAAATTTTTCAACAGCACACAAAATACTTTACTCATCACGGGTTCTCTGTATCTGGTGAGTTATCTTAGAAATCTAAT
CGTTGAGGGAGTTGGAGATA

Downstream 100 bases:

>100_bases
AACATCTGCTTCCGCTGATTTATCATTTGAATTATACTGTTAATAGGGGGGATGTGAGATGACCGCAATTATTTTAGCGG
CAGGACTTGGAAAAAGGATG

Product: RuvA domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MIKGVEGEITEISGNEVTLKAGQFYLNILCSTNTIKELSLSAKVHLLTYLSFSADRAPEIYGFKDRAEYNVFLMLLKANK
IGPKMALKILSATSPEMLQKMIASKDISGLSRLPGLGKKTAERLVSELYDLVKDYAVEFPKELSDVSEDAVGALTALGFD
MTSAKLAVNEVLKEQTVENTQELVRKALRKLNKTR

Sequences:

>Translated_195_residues
MIKGVEGEITEISGNEVTLKAGQFYLNILCSTNTIKELSLSAKVHLLTYLSFSADRAPEIYGFKDRAEYNVFLMLLKANK
IGPKMALKILSATSPEMLQKMIASKDISGLSRLPGLGKKTAERLVSELYDLVKDYAVEFPKELSDVSEDAVGALTALGFD
MTSAKLAVNEVLKEQTVENTQELVRKALRKLNKTR
>Mature_195_residues
MIKGVEGEITEISGNEVTLKAGQFYLNILCSTNTIKELSLSAKVHLLTYLSFSADRAPEIYGFKDRAEYNVFLMLLKANK
IGPKMALKILSATSPEMLQKMIASKDISGLSRLPGLGKKTAERLVSELYDLVKDYAVEFPKELSDVSEDAVGALTALGFD
MTSAKLAVNEVLKEQTVENTQELVRKALRKLNKTR

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=143, Percent_Identity=34.2657342657343, Blast_Score=83, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_KOSOT (C5CFS3)

Other databases:

- EMBL:   CP001634
- RefSeq:   YP_002941425.1
- GeneID:   7968136
- GenomeReviews:   CP001634_GR
- KEGG:   kol:Kole_1735
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 21535; Mature: 21535

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKGVEGEITEISGNEVTLKAGQFYLNILCSTNTIKELSLSAKVHLLTYLSFSADRAPEI
CCCCCCCCEEEECCCEEEEEECCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
YGFKDRAEYNVFLMLLKANKIGPKMALKILSATSPEMLQKMIASKDISGLSRLPGLGKKT
CCCCCCCCCEEEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHCCCCCHHH
AERLVSELYDLVKDYAVEFPKELSDVSEDAVGALTALGFDMTSAKLAVNEVLKEQTVENT
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
QELVRKALRKLNKTR
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MIKGVEGEITEISGNEVTLKAGQFYLNILCSTNTIKELSLSAKVHLLTYLSFSADRAPEI
CCCCCCCCEEEECCCEEEEEECCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
YGFKDRAEYNVFLMLLKANKIGPKMALKILSATSPEMLQKMIASKDISGLSRLPGLGKKT
CCCCCCCCCEEEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHCCCCCHHH
AERLVSELYDLVKDYAVEFPKELSDVSEDAVGALTALGFDMTSAKLAVNEVLKEQTVENT
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
QELVRKALRKLNKTR
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA