Click here to switch to the map view.

The map label for this gene is hutI

Identifier: 239618087

GI number: 239618087

Start: 1847839

End: 1849059

Strand: Reverse

Name: hutI

Synonym: Kole_1719

Alternate gene names: 239618087

Gene position: 1849059-1847839 (Counterclockwise)

Preceding gene: 239618088

Following gene: 239618086

Centisome position: 80.32

GC content: 43.73

Gene sequence:

>1221_bases
GTGAGGGTTGACCTCACAATAACAAACCTTTCAGAAATAGTTTCTCCAAAAGGCAAACCACCTGTCTGCGGCAAAAATAT
GTCGCAGCTCTCAATTCGAAAGAATAAGAATATAGCTATAAAAGATGGAAAAATCGTTTATATTGGTTCTGAAATCCCCC
CGGCTCTGCGAACAATAAACGCTAATGGCGCAATCGCCCTTCCGGGACTTGTGGATCCCCACACCCACATTCCATTTACC
GGTAACCGGGCTCATGAGTTCATAATGCGGCTTCACGGAAAAAGCTACATGGAGATCATGCAGGCGGGAGGTGGCATATT
ATCCACTGTTAAGGCAGTAAGAAAGGCCTCACTCAAAGAACTTGTTTTAAGAGGAGCATATGCACTGAATGAGATGCTAA
AGCTGGGAGTTACCACCGTTGAGGGGAAAAGCGGTTACGGGCTAGAAAAAACAGCTGAAATAAAGCAATTGAAAGCATTG
AAATTATTAAACAAAGTTCAACTTGTTGACGTTATCCCGACCTTTCTTGGGGCACATGCTTTACCAGAAGAATTCGAAGA
CAAGAAGGAGTATCTAAATTACCTTTCCAACATGCTCAAGGATGTGAGAGAATATACTGACACGGTAGATATTTTCTGTG
AAAAAGGAGTTTTCGAAGTCGAGGAATCGAGGGAATTCCTTGAAAGAGCTAAAGCCATGGGTTTCCGCTTGAGATTGCAC
GCCGATGAATTGGCACCCTCCGGGGCTGGTAAGCTCGCCGTTGAACTCGGAGCGGTATCCGCAGACCATCTCATATCCGC
TGATGACGAAACCCTCGAGGCTATCTCTAAAAGTGCAACAACAGCTGTTATCCTTCCGGGAACATCTTTCTTTCTGAAAG
AACGTTTCGCCAGAGGTAGAAAGATGATAGATCTGGGAAGTGCTGTTGCTCTGGCTTCTGATTTTAACCCTGGTTCGTGC
AATATATACGATCCTTATTTGATCATGCACCTGGCTGTTACCCGGTGTGGCTTGGAAATCGAAGAAGCTGTCACTGCTTA
CACCATAAACGCCGCTCATATTCTGAACCTTTCTAACAGGAAAGGAAAGATAGAAGAAGGGTACGATGCTGACATTGTTT
TATTGGGACTAAATTCCTATACTGAAATCCCTTACATGTTTTCACGAATTACTGTTGTTTCTGTAATAAAATCAGGCAGA
GTGGTTTTCCATGAATCTTGA

Upstream 100 bases:

>100_bases
TGAGTTCCGTTGCTGATTTCTATCTCAGACTGGAAAAATTTGATTCCAGTACCGTACTGGAAAACAAGATTCTTCAGAAG
ATAGTAGAGGAGGAATGAGT

Downstream 100 bases:

>100_bases
AATCTATCTAACGGGTAAAGTGAAAACCAAATTCATTTTAGAAGGTGTGGAACAATATCTAAAATGGATTAGACCATATC
ATAAAATTAAAATAACGTCT

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MRVDLTITNLSEIVSPKGKPPVCGKNMSQLSIRKNKNIAIKDGKIVYIGSEIPPALRTINANGAIALPGLVDPHTHIPFT
GNRAHEFIMRLHGKSYMEIMQAGGGILSTVKAVRKASLKELVLRGAYALNEMLKLGVTTVEGKSGYGLEKTAEIKQLKAL
KLLNKVQLVDVIPTFLGAHALPEEFEDKKEYLNYLSNMLKDVREYTDTVDIFCEKGVFEVEESREFLERAKAMGFRLRLH
ADELAPSGAGKLAVELGAVSADHLISADDETLEAISKSATTAVILPGTSFFLKERFARGRKMIDLGSAVALASDFNPGSC
NIYDPYLIMHLAVTRCGLEIEEAVTAYTINAAHILNLSNRKGKIEEGYDADIVLLGLNSYTEIPYMFSRITVVSVIKSGR
VVFHES

Sequences:

>Translated_406_residues
MRVDLTITNLSEIVSPKGKPPVCGKNMSQLSIRKNKNIAIKDGKIVYIGSEIPPALRTINANGAIALPGLVDPHTHIPFT
GNRAHEFIMRLHGKSYMEIMQAGGGILSTVKAVRKASLKELVLRGAYALNEMLKLGVTTVEGKSGYGLEKTAEIKQLKAL
KLLNKVQLVDVIPTFLGAHALPEEFEDKKEYLNYLSNMLKDVREYTDTVDIFCEKGVFEVEESREFLERAKAMGFRLRLH
ADELAPSGAGKLAVELGAVSADHLISADDETLEAISKSATTAVILPGTSFFLKERFARGRKMIDLGSAVALASDFNPGSC
NIYDPYLIMHLAVTRCGLEIEEAVTAYTINAAHILNLSNRKGKIEEGYDADIVLLGLNSYTEIPYMFSRITVVSVIKSGR
VVFHES
>Mature_406_residues
MRVDLTITNLSEIVSPKGKPPVCGKNMSQLSIRKNKNIAIKDGKIVYIGSEIPPALRTINANGAIALPGLVDPHTHIPFT
GNRAHEFIMRLHGKSYMEIMQAGGGILSTVKAVRKASLKELVLRGAYALNEMLKLGVTTVEGKSGYGLEKTAEIKQLKAL
KLLNKVQLVDVIPTFLGAHALPEEFEDKKEYLNYLSNMLKDVREYTDTVDIFCEKGVFEVEESREFLERAKAMGFRLRLH
ADELAPSGAGKLAVELGAVSADHLISADDETLEAISKSATTAVILPGTSFFLKERFARGRKMIDLGSAVALASDFNPGSC
NIYDPYLIMHLAVTRCGLEIEEAVTAYTINAAHILNLSNRKGKIEEGYDADIVLLGLNSYTEIPYMFSRITVVSVIKSGR
VVFHES

Specific function: Involved In The Anaerobic Utilization Of Allantoin. [C]

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family

Homologues:

Organism=Homo sapiens, GI223972677, Length=354, Percent_Identity=37.0056497175141, Blast_Score=229, Evalue=5e-60,
Organism=Caenorhabditis elegans, GI17555004, Length=370, Percent_Identity=37.5675675675676, Blast_Score=236, Evalue=2e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HUTI_KOSOT (C5CFQ7)

Other databases:

- EMBL:   CP001634
- RefSeq:   YP_002941409.1
- ProteinModelPortal:   C5CFQ7
- GeneID:   7968120
- GenomeReviews:   CP001634_GR
- KEGG:   kol:Kole_1719
- GO:   GO:0005737
- HAMAP:   MF_00372
- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01224

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.2.7

Molecular weight: Translated: 44498; Mature: 44498

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: NA

Important sites: BINDING 83-83 BINDING 96-96 BINDING 146-146 BINDING 179-179 BINDING 243-243

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVDLTITNLSEIVSPKGKPPVCGKNMSQLSIRKNKNIAIKDGKIVYIGSEIPPALRTIN
CEEEEEECCHHHHHCCCCCCCCCCCCHHHEEEECCCCEEEECCEEEEECCCCCHHHEEEC
ANGAIALPGLVDPHTHIPFTGNRAHEFIMRLHGKSYMEIMQAGGGILSTVKAVRKASLKE
CCCCEECCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
LVLRGAYALNEMLKLGVTTVEGKSGYGLEKTAEIKQLKALKLLNKVQLVDVIPTFLGAHA
HHHHHHHHHHHHHHHCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LPEEFEDKKEYLNYLSNMLKDVREYTDTVDIFCEKGVFEVEESREFLERAKAMGFRLRLH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCEEEEEE
ADELAPSGAGKLAVELGAVSADHLISADDETLEAISKSATTAVILPGTSFFLKERFARGR
HHHCCCCCCCCEEEEECCCCCCCEECCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCC
KMIDLGSAVALASDFNPGSCNIYDPYLIMHLAVTRCGLEIEEAVTAYTINAAHILNLSNR
EEEECCCCEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHEEEECHHEEEECCCC
KGKIEEGYDADIVLLGLNSYTEIPYMFSRITVVSVIKSGRVVFHES
CCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEECC
>Mature Secondary Structure
MRVDLTITNLSEIVSPKGKPPVCGKNMSQLSIRKNKNIAIKDGKIVYIGSEIPPALRTIN
CEEEEEECCHHHHHCCCCCCCCCCCCHHHEEEECCCCEEEECCEEEEECCCCCHHHEEEC
ANGAIALPGLVDPHTHIPFTGNRAHEFIMRLHGKSYMEIMQAGGGILSTVKAVRKASLKE
CCCCEECCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
LVLRGAYALNEMLKLGVTTVEGKSGYGLEKTAEIKQLKALKLLNKVQLVDVIPTFLGAHA
HHHHHHHHHHHHHHHCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LPEEFEDKKEYLNYLSNMLKDVREYTDTVDIFCEKGVFEVEESREFLERAKAMGFRLRLH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCEEEEEE
ADELAPSGAGKLAVELGAVSADHLISADDETLEAISKSATTAVILPGTSFFLKERFARGR
HHHCCCCCCCCEEEEECCCCCCCEECCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCC
KMIDLGSAVALASDFNPGSCNIYDPYLIMHLAVTRCGLEIEEAVTAYTINAAHILNLSNR
EEEECCCCEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHEEEECHHEEEECCCC
KGKIEEGYDADIVLLGLNSYTEIPYMFSRITVVSVIKSGRVVFHES
CCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA