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The map label for this gene is yfjD [C]

Identifier: 239618085

GI number: 239618085

Start: 1845967

End: 1847346

Strand: Reverse

Name: yfjD [C]

Synonym: Kole_1717

Alternate gene names: 239618085

Gene position: 1847346-1845967 (Counterclockwise)

Preceding gene: 239618086

Following gene: 239618084

Centisome position: 80.25

GC content: 41.3

Gene sequence:

>1380_bases
GTGGAAGAACCTGCCAGTAGTGGTGATCCTTTATCTATTATCATTAATCTCATTTTTTTGATTTTCCTGCTGTTTCTTTC
TGGGGTGTTTTCCGGTTCTGAGACTGCCCTCATGTCCGTCAGCAAGTTGAAATTGCGGAAGTACGCAGAAGACGAAAAAG
ATGACTCAAGAAAAGAAATGATAAACAAGTACATCGAACAACCAAACAAGATGCTGACAGCAATCCTTGTTATGAACAAT
CTCGTGAATATCCTTGCTTCAGCTGAGGCCACACTGTTAGCTCTTAAGTTGTTACCAGAAACGTCGGAGGGTGTTGCTGC
TGCAGTCGTCACAGGTATAATGACCTTCCTGATACTCGTTTTTGGAGAAATTACACCGAAGATATACGCAAGGGAGAATA
CAGAAAAAGTATTTAATAGTGTTATAGGTCTCATTTCCTTTATTACGATCGTACTCAAACCTGTGATATGGCTTCTTGTG
AGTCTATCGAATTTCTTCATAGTCATAATCGGGGGAAAATCAATGCGAGAGACGCCTTTTATCACTGAAGATGAGATCAT
ATCCGCTGTTGATGTTGGACACAAAGAAGGTGTCCTTCAAGATCAGGAAAGACAGATGATGAAACGTTCGCTGGAGCTTA
AGGATATTTCGGTAAGGGAAATCATGACACCAAGGGTTGAAATGGTATGCATGGAAGAGAATGAATCTCTTATGGATCTA
ATGAAAGTTGTCGAGGATGAGGGCTACTCGAGGATACCTGTTTATAGGGAAAACATTGACAGGATCGTGGGCGTTTGTTA
TGCCAAAGACCTTTTCAGGTACATCATCGATACCAATGACGAGAAAGAAACCCTTGAAAAAACTCCGGTAAAAGAGATGA
TGCGACAACCATATTTCGTCCCTGAGACAAAGAAAGTTGACGACCTTATGAAAGAATTTAAGGAACAGAAAATACACCTT
GCGATTGTCGTTGATGAATACGGCGGAACCGCTGGATTGGTTACAATGGAAGACATTCTTGAAGAACTCACCGGTGAAAT
CCTGGATGAATACGATATCGAAGCCGAAGAAATTACCATCAAAAAGGTGGGTGATAATGTTTATATAGTTGATGCCATGA
CACCCATCAACGACCTTGAAAGGGAACTCGACGTAAAGTTCCCGGAAACAGAATATGAGACCATCGGGGGATACCTGCTT
GAGATCCTTGAAAGGTTCCCGGAAATTGGCGAACGTATTGTGGTCGGAGATTTCATTTTTGAAATCCTTGCCGCAGGAAA
AAAGAAGATCGAAAAAATCAGACTAATAGTAGATCGGGGGAAGAAAAATGTTGCAGAAAGACCTGGAGAAAAAACTGATA
GAAATGGCAACAAAGGCTAA

Upstream 100 bases:

>100_bases
TTGTCTTACTTGAACAGCTGTACAGAGCTGAAACTATAAACCGTGGAATGATTTATCATTATTGAAAAACAACCGATATT
TTTTTGGAGGTGGAACAAGA

Downstream 100 bases:

>100_bases
AGAAAGGTCCTATTCTCCTTATTCCAACTTTGCCGTTGGAGCAGCACTGCTGACAGAAGATGGCGAGATATTTCTCGGAA
CAAACATCGAGAATTCTTCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MEEPASSGDPLSIIINLIFLIFLLFLSGVFSGSETALMSVSKLKLRKYAEDEKDDSRKEMINKYIEQPNKMLTAILVMNN
LVNILASAEATLLALKLLPETSEGVAAAVVTGIMTFLILVFGEITPKIYARENTEKVFNSVIGLISFITIVLKPVIWLLV
SLSNFFIVIIGGKSMRETPFITEDEIISAVDVGHKEGVLQDQERQMMKRSLELKDISVREIMTPRVEMVCMEENESLMDL
MKVVEDEGYSRIPVYRENIDRIVGVCYAKDLFRYIIDTNDEKETLEKTPVKEMMRQPYFVPETKKVDDLMKEFKEQKIHL
AIVVDEYGGTAGLVTMEDILEELTGEILDEYDIEAEEITIKKVGDNVYIVDAMTPINDLERELDVKFPETEYETIGGYLL
EILERFPEIGERIVVGDFIFEILAAGKKKIEKIRLIVDRGKKNVAERPGEKTDRNGNKG

Sequences:

>Translated_459_residues
MEEPASSGDPLSIIINLIFLIFLLFLSGVFSGSETALMSVSKLKLRKYAEDEKDDSRKEMINKYIEQPNKMLTAILVMNN
LVNILASAEATLLALKLLPETSEGVAAAVVTGIMTFLILVFGEITPKIYARENTEKVFNSVIGLISFITIVLKPVIWLLV
SLSNFFIVIIGGKSMRETPFITEDEIISAVDVGHKEGVLQDQERQMMKRSLELKDISVREIMTPRVEMVCMEENESLMDL
MKVVEDEGYSRIPVYRENIDRIVGVCYAKDLFRYIIDTNDEKETLEKTPVKEMMRQPYFVPETKKVDDLMKEFKEQKIHL
AIVVDEYGGTAGLVTMEDILEELTGEILDEYDIEAEEITIKKVGDNVYIVDAMTPINDLERELDVKFPETEYETIGGYLL
EILERFPEIGERIVVGDFIFEILAAGKKKIEKIRLIVDRGKKNVAERPGEKTDRNGNKG
>Mature_459_residues
MEEPASSGDPLSIIINLIFLIFLLFLSGVFSGSETALMSVSKLKLRKYAEDEKDDSRKEMINKYIEQPNKMLTAILVMNN
LVNILASAEATLLALKLLPETSEGVAAAVVTGIMTFLILVFGEITPKIYARENTEKVFNSVIGLISFITIVLKPVIWLLV
SLSNFFIVIIGGKSMRETPFITEDEIISAVDVGHKEGVLQDQERQMMKRSLELKDISVREIMTPRVEMVCMEENESLMDL
MKVVEDEGYSRIPVYRENIDRIVGVCYAKDLFRYIIDTNDEKETLEKTPVKEMMRQPYFVPETKKVDDLMKEFKEQKIHL
AIVVDEYGGTAGLVTMEDILEELTGEILDEYDIEAEEITIKKVGDNVYIVDAMTPINDLERELDVKFPETEYETIGGYLL
EILERFPEIGERIVVGDFIFEILAAGKKKIEKIRLIVDRGKKNVAERPGEKTDRNGNKG

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=386, Percent_Identity=26.9430051813472, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI40068055, Length=371, Percent_Identity=29.3800539083558, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI40068053, Length=371, Percent_Identity=29.3800539083558, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI94681046, Length=356, Percent_Identity=28.9325842696629, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI40068051, Length=317, Percent_Identity=26.813880126183, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI40068049, Length=210, Percent_Identity=31.4285714285714, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI145693175, Length=420, Percent_Identity=29.0476190476191, Blast_Score=194, Evalue=8e-51,
Organism=Escherichia coli, GI1790664, Length=444, Percent_Identity=26.1261261261261, Blast_Score=154, Evalue=9e-39,
Organism=Escherichia coli, GI1786879, Length=254, Percent_Identity=31.1023622047244, Blast_Score=145, Evalue=7e-36,
Organism=Escherichia coli, GI87082033, Length=252, Percent_Identity=28.968253968254, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1788119, Length=243, Percent_Identity=27.9835390946502, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71980512, Length=362, Percent_Identity=27.6243093922652, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17539402, Length=374, Percent_Identity=26.7379679144385, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17550766, Length=331, Percent_Identity=25.3776435045317, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6324512, Length=358, Percent_Identity=26.8156424581006, Blast_Score=81, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 52078; Mature: 52078

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEPASSGDPLSIIINLIFLIFLLFLSGVFSGSETALMSVSKLKLRKYAEDEKDDSRKEM
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHH
INKYIEQPNKMLTAILVMNNLVNILASAEATLLALKLLPETSEGVAAAVVTGIMTFLILV
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
FGEITPKIYARENTEKVFNSVIGLISFITIVLKPVIWLLVSLSNFFIVIIGGKSMRETPF
HHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCC
ITEDEIISAVDVGHKEGVLQDQERQMMKRSLELKDISVREIMTPRVEMVCMEENESLMDL
CCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEECCCHHHHHH
MKVVEDEGYSRIPVYRENIDRIVGVCYAKDLFRYIIDTNDEKETLEKTPVKEMMRQPYFV
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHCCCCC
PETKKVDDLMKEFKEQKIHLAIVVDEYGGTAGLVTMEDILEELTGEILDEYDIEAEEITI
CCCCHHHHHHHHHHHCCEEEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHCCCCHHHEEE
KKVGDNVYIVDAMTPINDLERELDVKFPETEYETIGGYLLEILERFPEIGERIVVGDFIF
EEECCCEEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEHHHHHH
EILAAGKKKIEKIRLIVDRGKKNVAERPGEKTDRNGNKG
HHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MEEPASSGDPLSIIINLIFLIFLLFLSGVFSGSETALMSVSKLKLRKYAEDEKDDSRKEM
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHH
INKYIEQPNKMLTAILVMNNLVNILASAEATLLALKLLPETSEGVAAAVVTGIMTFLILV
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
FGEITPKIYARENTEKVFNSVIGLISFITIVLKPVIWLLVSLSNFFIVIIGGKSMRETPF
HHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCC
ITEDEIISAVDVGHKEGVLQDQERQMMKRSLELKDISVREIMTPRVEMVCMEENESLMDL
CCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEECCCHHHHHH
MKVVEDEGYSRIPVYRENIDRIVGVCYAKDLFRYIIDTNDEKETLEKTPVKEMMRQPYFV
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHCCCCC
PETKKVDDLMKEFKEQKIHLAIVVDEYGGTAGLVTMEDILEELTGEILDEYDIEAEEITI
CCCCHHHHHHHHHHHCCEEEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHCCCCHHHEEE
KKVGDNVYIVDAMTPINDLERELDVKFPETEYETIGGYLLEILERFPEIGERIVVGDFIF
EEECCCEEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEHHHHHH
EILAAGKKKIEKIRLIVDRGKKNVAERPGEKTDRNGNKG
HHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]