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The map label for this gene is coaD

Identifier: 239618076

GI number: 239618076

Start: 1837456

End: 1837938

Strand: Reverse

Name: coaD

Synonym: Kole_1708

Alternate gene names: 239618076

Gene position: 1837938-1837456 (Counterclockwise)

Preceding gene: 239618077

Following gene: 239618075

Centisome position: 79.84

GC content: 40.58

Gene sequence:

>483_bases
GTGAAAGCAATTTATCCCGGATCCTTTGATCCAATAACCTACGGTCATATGGATATCTTAAAACGCGCTTCAAAGATCTT
CGATGAGGTTGTTGTTCTGGTAATGAAGAACATCAACAAAAGATACTTTTTTACTTTTTCCGAAAGGTTGTCGATGGTTG
AAAAAGCGGTTGAAGGAATTCAAAACGCTCGAGCAGATTCTTACGAAGGGTTATTGGTAGATTACGCTAGAAAGGCCGGT
ATCAAGATAGTAGTTAGAGGTCTTCGCGCTATCTCCGATTTTGAAATGGAGATTCAGGTGGCACACATCAATAAGGCCAT
GTACGCCGACCTGGAAACGGTTTTTCTCATGACGGATCCTAAATACTCTTTCTTATCTTCTTCTATTGTTAGAGAGGCTG
CAAGTTTCGGTGGAGATGTTTCTTTATGGGTTCCTCCATACGTTGAGGAAGCCCTGAAAAGAAAATTTTCAGGTTCAACT
TAA

Upstream 100 bases:

>100_bases
AAATGACGCTGGCTGATCTAATAGAAATAGGAGAAAAACTAAAAAAGAACAAACGGATAGAATTGCAACTCGAAGAGAAA
CCAGAAACGGGGGAGTCAAG

Downstream 100 bases:

>100_bases
CGACTTTGAAATATTATTTTCTCAAGTTAAGATATAATCCATAAGGAGATGTTAGAAAGGAGGAGACACAGAATGGCAAA
AATTACCGCTGACATGGTAA

Product: pantetheine-phosphate adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MKAIYPGSFDPITYGHMDILKRASKIFDEVVVLVMKNINKRYFFTFSERLSMVEKAVEGIQNARADSYEGLLVDYARKAG
IKIVVRGLRAISDFEMEIQVAHINKAMYADLETVFLMTDPKYSFLSSSIVREAASFGGDVSLWVPPYVEEALKRKFSGST

Sequences:

>Translated_160_residues
MKAIYPGSFDPITYGHMDILKRASKIFDEVVVLVMKNINKRYFFTFSERLSMVEKAVEGIQNARADSYEGLLVDYARKAG
IKIVVRGLRAISDFEMEIQVAHINKAMYADLETVFLMTDPKYSFLSSSIVREAASFGGDVSLWVPPYVEEALKRKFSGST
>Mature_160_residues
MKAIYPGSFDPITYGHMDILKRASKIFDEVVVLVMKNINKRYFFTFSERLSMVEKAVEGIQNARADSYEGLLVDYARKAG
IKIVVRGLRAISDFEMEIQVAHINKAMYADLETVFLMTDPKYSFLSSSIVREAASFGGDVSLWVPPYVEEALKRKFSGST

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=156, Percent_Identity=41.025641025641, Blast_Score=150, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_KOSOT (C5CFP6)

Other databases:

- EMBL:   CP001634
- RefSeq:   YP_002941398.1
- ProteinModelPortal:   C5CFP6
- GeneID:   7968108
- GenomeReviews:   CP001634_GR
- KEGG:   kol:Kole_1708
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18095; Mature: 18095

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIYPGSFDPITYGHMDILKRASKIFDEVVVLVMKNINKRYFFTFSERLSMVEKAVEGI
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHH
QNARADSYEGLLVDYARKAGIKIVVRGLRAISDFEMEIQVAHINKAMYADLETVFLMTDP
HHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCHHEEEEEHHHHHHHHCHHEEEEEECC
KYSFLSSSIVREAASFGGDVSLWVPPYVEEALKRKFSGST
CHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKAIYPGSFDPITYGHMDILKRASKIFDEVVVLVMKNINKRYFFTFSERLSMVEKAVEGI
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHH
QNARADSYEGLLVDYARKAGIKIVVRGLRAISDFEMEIQVAHINKAMYADLETVFLMTDP
HHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCHHEEEEEHHHHHHHHCHHEEEEEECC
KYSFLSSSIVREAASFGGDVSLWVPPYVEEALKRKFSGST
CHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA