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The map label for this gene is glpR [H]

Identifier: 239617092

GI number: 239617092

Start: 748108

End: 748866

Strand: Reverse

Name: glpR [H]

Synonym: Kole_0694

Alternate gene names: 239617092

Gene position: 748866-748108 (Counterclockwise)

Preceding gene: 239617094

Following gene: 239617091

Centisome position: 32.53

GC content: 41.24

Gene sequence:

>759_bases
ATGCTTACAGATGAAAGGCGCATGGCTATATTTGAATACATAAAAAAGAATTTCAGTGCTACGACCGAGGAATTGGCCGA
GCATTTCAACGTTTCAACCAGCACCATCAGAAGGGATCTTGAAAACCTCGCTTCTAAAAAACTCATAAAACGCACACACA
AAGGTGCGGTCATAAACTCTCCCCACGCTGAAAGCAGTTTTCTTGTCAACTACAACTATATGAGAGAAGAAAAGAAGCTC
ATCGCTAAAAAAGCCATGGCGTTTATCAACAACGATGAGTTCATAGCGTTGAGCGGCGGGACCACTTCCTACATGCTTGC
CACTGAGCTTATAAACTCAGAGCTTCAAGGTTTAAAGATTATAACTAACTCTATCAACATAGCAACGCTGATCCTTGAGA
GCAAGAAGGATTTTGTTCTCATAATGGCCGGCGGGATACCTCGAAAGGGTTCATATGAGTGTGTAGGGGAATTTACATTA
AGGACTATAAGAGCATTCAATATCGATAAGTTCTTTATGGGAGTAAATGGTATTTCAATCGAAGGAGGAATTTCTTTTTC
AAGTTTTGATGAGGCCTCCGTAGCCCAGGAATTTATGTTGAGAAGCAAGGAGAAGTATGTGATAGCAGACCACACAAAAT
TTGAAGTTACCAAACCGGCGAGAGTCGCTGAAATTGCAGAGGTTGATGCGATCATTACAGATGCTATACCCGAAGAAACG
AAATTTTCCTATACACAACTGGGGGCCAAGATAATTTGA

Upstream 100 bases:

>100_bases
GCCTACATTCGCTTTTCTATATTTGATGTATTCATATATAATCACTAATGTGCATTATAAATTATCATATTTGATTATTT
GTGATTGATGAGGTGATTAT

Downstream 100 bases:

>100_bases
TTTTGGGTCTGGAAAAAATTTTTTGGGAGGTGTGGTTTTATGAAGAAAGCCCTTGTTTTTATTCTCACCATGTTGGTAGT
GGTTGGGGTGGCTTTTTCGG

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MLTDERRMAIFEYIKKNFSATTEELAEHFNVSTSTIRRDLENLASKKLIKRTHKGAVINSPHAESSFLVNYNYMREEKKL
IAKKAMAFINNDEFIALSGGTTSYMLATELINSELQGLKIITNSINIATLILESKKDFVLIMAGGIPRKGSYECVGEFTL
RTIRAFNIDKFFMGVNGISIEGGISFSSFDEASVAQEFMLRSKEKYVIADHTKFEVTKPARVAEIAEVDAIITDAIPEET
KFSYTQLGAKII

Sequences:

>Translated_252_residues
MLTDERRMAIFEYIKKNFSATTEELAEHFNVSTSTIRRDLENLASKKLIKRTHKGAVINSPHAESSFLVNYNYMREEKKL
IAKKAMAFINNDEFIALSGGTTSYMLATELINSELQGLKIITNSINIATLILESKKDFVLIMAGGIPRKGSYECVGEFTL
RTIRAFNIDKFFMGVNGISIEGGISFSSFDEASVAQEFMLRSKEKYVIADHTKFEVTKPARVAEIAEVDAIITDAIPEET
KFSYTQLGAKII
>Mature_252_residues
MLTDERRMAIFEYIKKNFSATTEELAEHFNVSTSTIRRDLENLASKKLIKRTHKGAVINSPHAESSFLVNYNYMREEKKL
IAKKAMAFINNDEFIALSGGTTSYMLATELINSELQGLKIITNSINIATLILESKKDFVLIMAGGIPRKGSYECVGEFTL
RTIRAFNIDKFFMGVNGISIEGGISFSSFDEASVAQEFMLRSKEKYVIADHTKFEVTKPARVAEIAEVDAIITDAIPEET
KFSYTQLGAKII

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=237, Percent_Identity=34.5991561181435, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1789059, Length=236, Percent_Identity=31.7796610169492, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87082344, Length=215, Percent_Identity=30.2325581395349, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1788069, Length=239, Percent_Identity=29.2887029288703, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI226510968, Length=243, Percent_Identity=29.6296296296296, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1789519, Length=254, Percent_Identity=27.5590551181102, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789170, Length=234, Percent_Identity=30.3418803418803, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1790753, Length=254, Percent_Identity=26.3779527559055, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787540, Length=233, Percent_Identity=26.1802575107296, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1787063, Length=256, Percent_Identity=24.609375, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1790635, Length=146, Percent_Identity=26.7123287671233, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28251; Mature: 28251

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTDERRMAIFEYIKKNFSATTEELAEHFNVSTSTIRRDLENLASKKLIKRTHKGAVINS
CCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEC
PHAESSFLVNYNYMREEKKLIAKKAMAFINNDEFIALSGGTTSYMLATELINSELQGLKI
CCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCEEE
ITNSINIATLILESKKDFVLIMAGGIPRKGSYECVGEFTLRTIRAFNIDKFFMGVNGISI
EECCCEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHEECCCCEEE
EGGISFSSFDEASVAQEFMLRSKEKYVIADHTKFEVTKPARVAEIAEVDAIITDAIPEET
ECCCCCCCCCHHHHHHHHHHCCCCCEEEECCCEEEECCCHHHHHHHHHHHHHHCCCCCCC
KFSYTQLGAKII
CCHHHHCCCCCC
>Mature Secondary Structure
MLTDERRMAIFEYIKKNFSATTEELAEHFNVSTSTIRRDLENLASKKLIKRTHKGAVINS
CCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEC
PHAESSFLVNYNYMREEKKLIAKKAMAFINNDEFIALSGGTTSYMLATELINSELQGLKI
CCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCEEE
ITNSINIATLILESKKDFVLIMAGGIPRKGSYECVGEFTLRTIRAFNIDKFFMGVNGISI
EECCCEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHEECCCCEEE
EGGISFSSFDEASVAQEFMLRSKEKYVIADHTKFEVTKPARVAEIAEVDAIITDAIPEET
ECCCCCCCCCHHHHHHHHHHCCCCCEEEECCCEEEECCCHHHHHHHHHHHHHHCCCCCCC
KFSYTQLGAKII
CCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8955387; 3045764; 9278503 [H]