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The map label for this gene is menC [H]

Identifier: 239617080

GI number: 239617080

Start: 733555

End: 734730

Strand: Reverse

Name: menC [H]

Synonym: Kole_0682

Alternate gene names: 239617080

Gene position: 734730-733555 (Counterclockwise)

Preceding gene: 239617081

Following gene: 239617079

Centisome position: 31.92

GC content: 44.3

Gene sequence:

>1176_bases
ATGATAACTGAATCAGCAAGAATAGATGGCGTTAGTTTGTATGAGATAGTAATCCCAATGAAGATACCCTTCCAGATAAG
CTCGGGTACCTGCTATACGAGAAGATCCCTTGTTGTGGAGATTCGTGAGGGTGACCTTTTTGGTTATGGAGAATCAGCTC
CTTTTGAAGAACCCTTCTATCTGGGAGAAACTCTGGAAACAACCAAAGTTATCCTGAAGAATCATCTTCTTCCGATGATT
CTTGGAAAAGAACCTTTGTCGATTGAAGAGTTCAATCACCTCATCAAAAACGGGATTCGTGGTAACCACTTCGCGAGATG
TGGAGTGGAGAACGCTTACTGGGATCTCATCGCAAAGAAAAACAAGATATCTTTGAAAGCAATGATAGAGAAGAAAATGA
AAAATTTAGGAGTAAAACAAGAATATCTTGCTTCCAATAATTACATAGAATCGGGTGCCGCTCTTGGAATACCGGAAGAT
GGCAGGATCGAAACCCTGATACACCAGGTGGAGGAATCTCTTCAGGAAGGCTACAGGAGGATAAAGATAAAGATAAAACC
CGGATGGGACGTGGAGCCTCTTCAAGAAACCAGAAGGGCAGTTGGAGATCATTTTCCTCTGTGGACTGACGCAAATTCTT
CTTTTGAGCTCGATCAGTGGGAAACGTTTAAAGCTATGGATGCAGCCAAATGCCTTTTTCACGAGCAGCCGTTACATTAT
GAGGCTCTGTTAGATCTGAAAGAGCTTGGTGAAAGGATAGAGACGCCGATCTGCCTTGACGAGTCTTTGATTTCCTCGCG
AGTAGCCGAATTTGTGGCGAAATTGGGAATATCCAATATCTGGAACATAAAAATCCAGCGGGTTGGAGGGTTGCTGGAAG
CCATTAAGATCTACAAGATTGCCACAGACAACGGAATAAAACTTTGGGGCGGTACTATGCCAGAAAGCGGGCTGGGTGCG
AGGTTTTTGATTAGCCTGGCTTCTTTCAGAGGATTTGTTTTTCCTGCTGATGTAGCGGCCAGCGAGAAATGGTACGGCAA
GGGAAATGATCTGGTTGAGAACACCATGACGGATGGGAAGATCTATGTACCGGATGAACCTGGAGCGAGTTTTGATATGA
CCTTAAGTCATCTGGAAGCTCTGGGCAAAAAAATCTGGGAGAGTCAAAGGGGTTGA

Upstream 100 bases:

>100_bases
GCAATGAAATGGCTTGAAGAAAAAGGTTATCTCTTTAGGGTAGATGATCTTTTAAGATTCCTGGACATATTTGATCACAG
CATTGAAAGGAGCTGTAGTG

Downstream 100 bases:

>100_bases
ATACAAATGACGAAGATAAGCTCAAAAAAATACATGGCAGCGTATTTGCTTCTCCTTCCAAATATCATTCTGTACATACT
GGTAAGGCTTATTCCCCTGT

Product: Mandelate racemase/muconate lactonizing protein

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MITESARIDGVSLYEIVIPMKIPFQISSGTCYTRRSLVVEIREGDLFGYGESAPFEEPFYLGETLETTKVILKNHLLPMI
LGKEPLSIEEFNHLIKNGIRGNHFARCGVENAYWDLIAKKNKISLKAMIEKKMKNLGVKQEYLASNNYIESGAALGIPED
GRIETLIHQVEESLQEGYRRIKIKIKPGWDVEPLQETRRAVGDHFPLWTDANSSFELDQWETFKAMDAAKCLFHEQPLHY
EALLDLKELGERIETPICLDESLISSRVAEFVAKLGISNIWNIKIQRVGGLLEAIKIYKIATDNGIKLWGGTMPESGLGA
RFLISLASFRGFVFPADVAASEKWYGKGNDLVENTMTDGKIYVPDEPGASFDMTLSHLEALGKKIWESQRG

Sequences:

>Translated_391_residues
MITESARIDGVSLYEIVIPMKIPFQISSGTCYTRRSLVVEIREGDLFGYGESAPFEEPFYLGETLETTKVILKNHLLPMI
LGKEPLSIEEFNHLIKNGIRGNHFARCGVENAYWDLIAKKNKISLKAMIEKKMKNLGVKQEYLASNNYIESGAALGIPED
GRIETLIHQVEESLQEGYRRIKIKIKPGWDVEPLQETRRAVGDHFPLWTDANSSFELDQWETFKAMDAAKCLFHEQPLHY
EALLDLKELGERIETPICLDESLISSRVAEFVAKLGISNIWNIKIQRVGGLLEAIKIYKIATDNGIKLWGGTMPESGLGA
RFLISLASFRGFVFPADVAASEKWYGKGNDLVENTMTDGKIYVPDEPGASFDMTLSHLEALGKKIWESQRG
>Mature_391_residues
MITESARIDGVSLYEIVIPMKIPFQISSGTCYTRRSLVVEIREGDLFGYGESAPFEEPFYLGETLETTKVILKNHLLPMI
LGKEPLSIEEFNHLIKNGIRGNHFARCGVENAYWDLIAKKNKISLKAMIEKKMKNLGVKQEYLASNNYIESGAALGIPED
GRIETLIHQVEESLQEGYRRIKIKIKPGWDVEPLQETRRAVGDHFPLWTDANSSFELDQWETFKAMDAAKCLFHEQPLHY
EALLDLKELGERIETPICLDESLISSRVAEFVAKLGISNIWNIKIQRVGGLLEAIKIYKIATDNGIKLWGGTMPESGLGA
RFLISLASFRGFVFPADVAASEKWYGKGNDLVENTMTDGKIYVPDEPGASFDMTLSHLEALGKKIWESQRG

Specific function: Converts SHCHC to OSB [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354
- InterPro:   IPR010197 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 44018; Mature: 44018

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITESARIDGVSLYEIVIPMKIPFQISSGTCYTRRSLVVEIREGDLFGYGESAPFEEPFY
CCCCCCCCCCEEEEEEEEEEEECEEECCCCEEEECEEEEEEECCCEECCCCCCCCCCCCC
LGETLETTKVILKNHLLPMILGKEPLSIEEFNHLIKNGIRGNHFARCGVENAYWDLIAKK
CCCHHHHHHHHHHHCCHHEEECCCCCCHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHCC
NKISLKAMIEKKMKNLGVKQEYLASNNYIESGAALGIPEDGRIETLIHQVEESLQEGYRR
CCHHHHHHHHHHHHHCCCCHHHHHCCCEECCCCEECCCCCCHHHHHHHHHHHHHHHHHHE
IKIKIKPGWDVEPLQETRRAVGDHFPLWTDANSSFELDQWETFKAMDAAKCLFHEQPLHY
EEEEECCCCCCCHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCH
EALLDLKELGERIETPICLDESLISSRVAEFVAKLGISNIWNIKIQRVGGLLEAIKIYKI
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHEEEE
ATDNGIKLWGGTMPESGLGARFLISLASFRGFVFPADVAASEKWYGKGNDLVENTMTDGK
ECCCCEEEECCCCCCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCHHHHHCCCCCE
IYVPDEPGASFDMTLSHLEALGKKIWESQRG
EECCCCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MITESARIDGVSLYEIVIPMKIPFQISSGTCYTRRSLVVEIREGDLFGYGESAPFEEPFY
CCCCCCCCCCEEEEEEEEEEEECEEECCCCEEEECEEEEEEECCCEECCCCCCCCCCCCC
LGETLETTKVILKNHLLPMILGKEPLSIEEFNHLIKNGIRGNHFARCGVENAYWDLIAKK
CCCHHHHHHHHHHHCCHHEEECCCCCCHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHCC
NKISLKAMIEKKMKNLGVKQEYLASNNYIESGAALGIPEDGRIETLIHQVEESLQEGYRR
CCHHHHHHHHHHHHHCCCCHHHHHCCCEECCCCEECCCCCCHHHHHHHHHHHHHHHHHHE
IKIKIKPGWDVEPLQETRRAVGDHFPLWTDANSSFELDQWETFKAMDAAKCLFHEQPLHY
EEEEECCCCCCCHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCH
EALLDLKELGERIETPICLDESLISSRVAEFVAKLGISNIWNIKIQRVGGLLEAIKIYKI
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHEEEE
ATDNGIKLWGGTMPESGLGARFLISLASFRGFVFPADVAASEKWYGKGNDLVENTMTDGK
ECCCCEEEECCCCCCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCHHHHHCCCCCE
IYVPDEPGASFDMTLSHLEALGKKIWESQRG
EECCCCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10194342 [H]