Click here to switch to the map view.

The map label for this gene is 239617030

Identifier: 239617030

GI number: 239617030

Start: 677496

End: 677891

Strand: Reverse

Name: 239617030

Synonym: Kole_0631

Alternate gene names: NA

Gene position: 677891-677496 (Counterclockwise)

Preceding gene: 239617031

Following gene: 239617029

Centisome position: 29.45

GC content: 37.63

Gene sequence:

>396_bases
GTGAAGCATATAAAATGTCCTTTTTGTAACCCGGATAATAGTGAAATTATCTTAAAAAACGATCTCTGTTATGCGAGGTT
TGACAAATACCCTGTTAGCACTGGGCACGTTCTTGTGATCCCATTCAGGCATTTCAGCAATTATTTTGAAGCAACAATGG
AAGAAAAGATTGCAATGGTGAGGTTAATAGATGAAGTAAAAGAATTTCTGGACAGGAAGTTTAAGCCTGATGGATATAAT
ATTGGTGTAAACGTTGGAAAGCCTGCTGGCCAAACTGTAATGCACGTTCATATCCATGTGATACCAAGATACAAAGGTGA
TATTGAAGATCCAACAGGTGGAGTTAGAGGTGTTATTTCTGCCAGAAGAATATATGATGATACTCCGAACGAATAG

Upstream 100 bases:

>100_bases
CGGCATTAAGAACACTGGCGATGAACCTTTAATGGTACTGGTTCTTAAAGCACCGCGTCCTCAATCTTGAAAATGAGTGT
AACTATAACCGGAGGGTAGT

Downstream 100 bases:

>100_bases
CGTTTGAATTGAAAGGGTAAAAGCGAATTTATATTTTGTATAGTATTCAACAAGAAGACGGGAGCTCGTGCTCCCGTTTT
TGTTTGTGTGGATTCACCGA

Product: histidine triad (HIT) protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MKHIKCPFCNPDNSEIILKNDLCYARFDKYPVSTGHVLVIPFRHFSNYFEATMEEKIAMVRLIDEVKEFLDRKFKPDGYN
IGVNVGKPAGQTVMHVHIHVIPRYKGDIEDPTGGVRGVISARRIYDDTPNE

Sequences:

>Translated_131_residues
MKHIKCPFCNPDNSEIILKNDLCYARFDKYPVSTGHVLVIPFRHFSNYFEATMEEKIAMVRLIDEVKEFLDRKFKPDGYN
IGVNVGKPAGQTVMHVHIHVIPRYKGDIEDPTGGVRGVISARRIYDDTPNE
>Mature_131_residues
MKHIKCPFCNPDNSEIILKNDLCYARFDKYPVSTGHVLVIPFRHFSNYFEATMEEKIAMVRLIDEVKEFLDRKFKPDGYN
IGVNVGKPAGQTVMHVHIHVIPRYKGDIEDPTGGVRGVISARRIYDDTPNE

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI261278358, Length=95, Percent_Identity=33.6842105263158, Blast_Score=63, Evalue=8e-11,
Organism=Homo sapiens, GI4503719, Length=95, Percent_Identity=33.6842105263158, Blast_Score=63, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6320511, Length=92, Percent_Identity=33.695652173913, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 15036; Mature: 15036

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHIKCPFCNPDNSEIILKNDLCYARFDKYPVSTGHVLVIPFRHFSNYFEATMEEKIAMV
CCCCCCCCCCCCCCEEEEECCCEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
RLIDEVKEFLDRKFKPDGYNIGVNVGKPAGQTVMHVHIHVIPRYKGDIEDPTGGVRGVIS
HHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEEEEEEECCCCCCCCCCCCHHHHHH
ARRIYDDTPNE
HHHHCCCCCCC
>Mature Secondary Structure
MKHIKCPFCNPDNSEIILKNDLCYARFDKYPVSTGHVLVIPFRHFSNYFEATMEEKIAMV
CCCCCCCCCCCCCCEEEEECCCEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
RLIDEVKEFLDRKFKPDGYNIGVNVGKPAGQTVMHVHIHVIPRYKGDIEDPTGGVRGVIS
HHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEEEEEEECCCCCCCCCCCCHHHHHH
ARRIYDDTPNE
HHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8899719; 11427726 [H]