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The map label for this gene is rbsR [H]

Identifier: 239617005

GI number: 239617005

Start: 652737

End: 653732

Strand: Reverse

Name: rbsR [H]

Synonym: Kole_0605

Alternate gene names: 239617005

Gene position: 653732-652737 (Counterclockwise)

Preceding gene: 239617007

Following gene: 239617004

Centisome position: 28.4

GC content: 40.66

Gene sequence:

>996_bases
ATGAAGTCAAAACATGTGAGTATCAGGGATGTTGCAAAGCATGCAGGAGTATCGATAGCCACCGTTTCAAGGGTTTTCAA
CAAAACTTCCTTTGTTAGCGAAGAGTTGGTAGAAAAAGTTCTAACATCCGCCAGAGAGCTCGGATATCATCCCAATAGAG
TTGCTCAAAGCCTTAGAAAAGGCCAAACAAAAACAATAGGGTTTTTGATTCCGGATATTGTTAATCCTTTCTTTTCCTCT
ATGGTGAAAGGGGCAGAAGATTTTTTGAAGTCTCTCGGGTATATTATTTTACTCTGCAGTTCTTCTGGGGACAGAGAAAA
AGAAAACGAGCTTCTTGCCACATTCTATTCAAGGAAGATAGATGGGTTAATCGCAATAACCCTTGAAGAGAACAATCCAC
TGATAGATTCTGCGATCTCCAAAAAGATCCCAACTATTTTGATGGATAACATTGTAAATCGTCCAACTATTTCATGCGTT
GCTTCTGATAACTATGGCGGTATCAAGAAATTAATGAATTACCTTATAGAGACCGGGCATCGTTCCTTCGTCTTTTTAAG
TGGTGATCCAATCATTCATTCAGCCAAAGAAAGGCTCAAAGCGTTTAAAGATACTGTTGAAGGCAGAAACGACCTCAATT
TTGAAATTGTTTTTGGAGAGTACACTTATGAAAGCGGCGTTGAAATGGTTAAAAAGCTAAAACATATTCCAGATGCTGTT
GTCTGCGGAAATGACATGATAGCTTTTGGGGCAATGGTTGAACTTGAAAGGCGGGGATTTCGGATACCGCAAGACGTTTC
TGTTACGGGATTTGATGACATACTGTTTTCAAGGATGAGTCGGCCGCCTTTGACAACAGTCAGGCAGGACGCTTATTTAA
TGGGGCGTGTCGGGGCTGAATTATTAATCAGCGCGATCAACGAGGAGATTAAGAATGATGTAGTTCTTTTGGAAACAACC
CTTGAGATTAGGGGGAGTACCCGTGAAAGAAAATGA

Upstream 100 bases:

>100_bases
AATTAGCTACTAATGAAGATGAACAAAGTTGGTTTTGAATCCATGGGTATGCTTAAATACTTCATGTAAACGTTTACGTA
AACGTTTTCAGGAGGGGAAA

Downstream 100 bases:

>100_bases
GCCCATCCTGATAATGAAAGGAATTACAAAGCGTTTCCCTGGTGTACTTGCTCTAAATAAGGTAGATTTCCGGTTAAAAC
ATGGGGAAATACACGCTCTT

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MKSKHVSIRDVAKHAGVSIATVSRVFNKTSFVSEELVEKVLTSARELGYHPNRVAQSLRKGQTKTIGFLIPDIVNPFFSS
MVKGAEDFLKSLGYIILLCSSSGDREKENELLATFYSRKIDGLIAITLEENNPLIDSAISKKIPTILMDNIVNRPTISCV
ASDNYGGIKKLMNYLIETGHRSFVFLSGDPIIHSAKERLKAFKDTVEGRNDLNFEIVFGEYTYESGVEMVKKLKHIPDAV
VCGNDMIAFGAMVELERRGFRIPQDVSVTGFDDILFSRMSRPPLTTVRQDAYLMGRVGAELLISAINEEIKNDVVLLETT
LEIRGSTRERK

Sequences:

>Translated_331_residues
MKSKHVSIRDVAKHAGVSIATVSRVFNKTSFVSEELVEKVLTSARELGYHPNRVAQSLRKGQTKTIGFLIPDIVNPFFSS
MVKGAEDFLKSLGYIILLCSSSGDREKENELLATFYSRKIDGLIAITLEENNPLIDSAISKKIPTILMDNIVNRPTISCV
ASDNYGGIKKLMNYLIETGHRSFVFLSGDPIIHSAKERLKAFKDTVEGRNDLNFEIVFGEYTYESGVEMVKKLKHIPDAV
VCGNDMIAFGAMVELERRGFRIPQDVSVTGFDDILFSRMSRPPLTTVRQDAYLMGRVGAELLISAINEEIKNDVVLLETT
LEIRGSTRERK
>Mature_331_residues
MKSKHVSIRDVAKHAGVSIATVSRVFNKTSFVSEELVEKVLTSARELGYHPNRVAQSLRKGQTKTIGFLIPDIVNPFFSS
MVKGAEDFLKSLGYIILLCSSSGDREKENELLATFYSRKIDGLIAITLEENNPLIDSAISKKIPTILMDNIVNRPTISCV
ASDNYGGIKKLMNYLIETGHRSFVFLSGDPIIHSAKERLKAFKDTVEGRNDLNFEIVFGEYTYESGVEMVKKLKHIPDAV
VCGNDMIAFGAMVELERRGFRIPQDVSVTGFDDILFSRMSRPPLTTVRQDAYLMGRVGAELLISAINEEIKNDVVLLETT
LEIRGSTRERK

Specific function: Transcriptional repressor for the ribose rbsDACBK operon [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=332, Percent_Identity=32.8313253012048, Blast_Score=174, Evalue=5e-45,
Organism=Escherichia coli, GI1790369, Length=342, Percent_Identity=30.1169590643275, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1787948, Length=308, Percent_Identity=32.7922077922078, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1789202, Length=291, Percent_Identity=32.3024054982818, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI1788474, Length=309, Percent_Identity=30.42071197411, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI48994940, Length=334, Percent_Identity=29.940119760479, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1786540, Length=331, Percent_Identity=29.0030211480363, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1789068, Length=290, Percent_Identity=29.6551724137931, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787906, Length=327, Percent_Identity=27.5229357798165, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1790715, Length=320, Percent_Identity=26.875, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787580, Length=318, Percent_Identity=25.4716981132075, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1786268, Length=311, Percent_Identity=25.08038585209, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789456, Length=344, Percent_Identity=27.6162790697674, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790689, Length=324, Percent_Identity=23.7654320987654, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36957; Mature: 36957

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSKHVSIRDVAKHAGVSIATVSRVFNKTSFVSEELVEKVLTSARELGYHPNRVAQSLRK
CCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHC
GQTKTIGFLIPDIVNPFFSSMVKGAEDFLKSLGYIILLCSSSGDREKENELLATFYSRKI
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHCC
DGLIAITLEENNPLIDSAISKKIPTILMDNIVNRPTISCVASDNYGGIKKLMNYLIETGH
CCEEEEEECCCCCHHHHHHHHHCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCC
RSFVFLSGDPIIHSAKERLKAFKDTVEGRNDLNFEIVFGEYTYESGVEMVKKLKHIPDAV
CEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCEE
VCGNDMIAFGAMVELERRGFRIPQDVSVTGFDDILFSRMSRPPLTTVRQDAYLMGRVGAE
EECCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LLISAINEEIKNDVVLLETTLEIRGSTRERK
HHHHHHHHHHHCCEEEEEEEEEECCCCCCCC
>Mature Secondary Structure
MKSKHVSIRDVAKHAGVSIATVSRVFNKTSFVSEELVEKVLTSARELGYHPNRVAQSLRK
CCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHC
GQTKTIGFLIPDIVNPFFSSMVKGAEDFLKSLGYIILLCSSSGDREKENELLATFYSRKI
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHCC
DGLIAITLEENNPLIDSAISKKIPTILMDNIVNRPTISCVASDNYGGIKKLMNYLIETGH
CCEEEEEECCCCCHHHHHHHHHCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCC
RSFVFLSGDPIIHSAKERLKAFKDTVEGRNDLNFEIVFGEYTYESGVEMVKKLKHIPDAV
CEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCEE
VCGNDMIAFGAMVELERRGFRIPQDVSVTGFDDILFSRMSRPPLTTVRQDAYLMGRVGAE
EECCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LLISAINEEIKNDVVLLETTLEIRGSTRERK
HHHHHHHHHHHCCEEEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]