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The map label for this gene is yqaB [C]

Identifier: 239616977

GI number: 239616977

Start: 624578

End: 625231

Strand: Reverse

Name: yqaB [C]

Synonym: Kole_0576

Alternate gene names: 239616977

Gene position: 625231-624578 (Counterclockwise)

Preceding gene: 239616978

Following gene: 239616976

Centisome position: 27.16

GC content: 39.91

Gene sequence:

>654_bases
TTGATCGATGCAGTGATATTTGACATGGATGGGGTTATCGTTGATACGGAAGGATTGTATAGAGAAGCCTGCAAAGAGGT
TGTCAGGAGATACGGTGGAATCATTACAGAAGAACTGTTTATTCGTCAGATGGGACTGAGAATGAAAGAAGCACAAAAGA
TCGTTGTGGAGCTTGCGAAACTTCCATTGGCTCCTGAGGATTTCGGAAAAGAATACATGGAGGAGTTTCTGAAAAGAGCA
AAAAGCAAGCTGAAACCAAACGATGGCCTTCTGGAATTGCTGGACTTTTTGTACAGCAAAGTTAAATTAGGTGTTGCTTC
ATCAACTGTGAGTAATGTTGTCTACGATATTTTAAGAACCATCGATGTCCTTAATTATTTCGATTACGTCATCGGGGGAG
ATATGGTAGAAAATGCCAAACCAGCTCCCGACATATATCTTAAATGTGCTGAGCATCTCAAAGTAGAGCCAGAAAACTGT
ATTGCCATAGAAGATTCACCAGTTGGAATAAAAAGTGCGAAAACTTCTGGAATGATTGTTTATGCTATAAGACACAAAGA
AAACCAAGGTTTAGACCTGAGTCAGGCTGATAAGGTTTTTGATGGGTTAAGACAGCTTAAAGGGTTTATGGTTGAGAAGT
TGCAAAGCAACTGA

Upstream 100 bases:

>100_bases
TAGACATCGATGTGTTCAATAACATCGTTATGCTTAGAAGAGAAACGATAAAAAAACTTGTGAAGAATCTCAAATCCATT
CTCAATCTGAGGTGATTTTC

Downstream 100 bases:

>100_bases
AGTGTGATTCGCTAATGTGAACGAAGCGAATGTACCTTGCCCAACATAGCCACTGCGAAGCAGTGCACATCGGTTCTCGG
ACTCTCGGTTATCGATTTTT

Product: HAD-superfamily hydrolase, subfamily IA, variant 3

Products: beta-D-glucose 6-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MIDAVIFDMDGVIVDTEGLYREACKEVVRRYGGIITEELFIRQMGLRMKEAQKIVVELAKLPLAPEDFGKEYMEEFLKRA
KSKLKPNDGLLELLDFLYSKVKLGVASSTVSNVVYDILRTIDVLNYFDYVIGGDMVENAKPAPDIYLKCAEHLKVEPENC
IAIEDSPVGIKSAKTSGMIVYAIRHKENQGLDLSQADKVFDGLRQLKGFMVEKLQSN

Sequences:

>Translated_217_residues
MIDAVIFDMDGVIVDTEGLYREACKEVVRRYGGIITEELFIRQMGLRMKEAQKIVVELAKLPLAPEDFGKEYMEEFLKRA
KSKLKPNDGLLELLDFLYSKVKLGVASSTVSNVVYDILRTIDVLNYFDYVIGGDMVENAKPAPDIYLKCAEHLKVEPENC
IAIEDSPVGIKSAKTSGMIVYAIRHKENQGLDLSQADKVFDGLRQLKGFMVEKLQSN
>Mature_217_residues
MIDAVIFDMDGVIVDTEGLYREACKEVVRRYGGIITEELFIRQMGLRMKEAQKIVVELAKLPLAPEDFGKEYMEEFLKRA
KSKLKPNDGLLELLDFLYSKVKLGVASSTVSNVVYDILRTIDVLNYFDYVIGGDMVENAKPAPDIYLKCAEHLKVEPENC
IAIEDSPVGIKSAKTSGMIVYAIRHKENQGLDLSQADKVFDGLRQLKGFMVEKLQSN

Specific function: Displays high phosphatase activity toward erythrose 4- phosphate, fructose 6-phosphate, 2-deoxyglucose 6-phosphate, and mannose 6-phosphate. May have a role in the intracellular metabolism of many phosphorylated carbohydrates [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily [H]

Homologues:

Organism=Homo sapiens, GI197382691, Length=196, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=4e-17,
Organism=Homo sapiens, GI207113149, Length=216, Percent_Identity=25.9259259259259, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI296011028, Length=168, Percent_Identity=27.3809523809524, Blast_Score=68, Evalue=7e-12,
Organism=Escherichia coli, GI1789046, Length=180, Percent_Identity=30, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1788021, Length=196, Percent_Identity=29.5918367346939, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787576, Length=194, Percent_Identity=27.319587628866, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1790151, Length=182, Percent_Identity=29.1208791208791, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789787, Length=108, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17554716, Length=194, Percent_Identity=30.9278350515464, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI116008157, Length=217, Percent_Identity=29.4930875576037, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI17137324, Length=215, Percent_Identity=30.2325581395349, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI20129151, Length=190, Percent_Identity=28.4210526315789, Blast_Score=82, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 5.4.2.6

Molecular weight: Translated: 24432; Mature: 24432

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDAVIFDMDGVIVDTEGLYREACKEVVRRYGGIITEELFIRQMGLRMKEAQKIVVELAK
CCCEEEECCCCEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHH
LPLAPEDFGKEYMEEFLKRAKSKLKPNDGLLELLDFLYSKVKLGVASSTVSNVVYDILRT
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDVLNYFDYVIGGDMVENAKPAPDIYLKCAEHLKVEPENCIAIEDSPVGIKSAKTSGMIV
HHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCEEE
YAIRHKENQGLDLSQADKVFDGLRQLKGFMVEKLQSN
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIDAVIFDMDGVIVDTEGLYREACKEVVRRYGGIITEELFIRQMGLRMKEAQKIVVELAK
CCCEEEECCCCEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHH
LPLAPEDFGKEYMEEFLKRAKSKLKPNDGLLELLDFLYSKVKLGVASSTVSNVVYDILRT
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDVLNYFDYVIGGDMVENAKPAPDIYLKCAEHLKVEPENCIAIEDSPVGIKSAKTSGMIV
HHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCEEE
YAIRHKENQGLDLSQADKVFDGLRQLKGFMVEKLQSN
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: beta-D-glucose 1-phosphate

Specific reaction: beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]