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The map label for this gene is fruK [H]

Identifier: 239616753

GI number: 239616753

Start: 364634

End: 365593

Strand: Direct

Name: fruK [H]

Synonym: Kole_0346

Alternate gene names: 239616753

Gene position: 364634-365593 (Clockwise)

Preceding gene: 239616752

Following gene: 239616754

Centisome position: 15.84

GC content: 42.71

Gene sequence:

>960_bases
TTGCGTGTTCTTACAGTAACGCTAAACCCTGCTCTAGACAGGGAACTTGTTGTTGAGAACTTTACAATAAACAACCTGCA
TCGTGTTAAGAACCAGAAGTATTCCATAATGGAACCTGGAGGAAAGGGAATAAACGTCTCACTCATTCTGTCCGGATTTG
GAATCCCAAGTATAGCCATGGGATTCATTGGAGGATATATAGGAGCTGTTGTCGAAAGCAGATTGAGAAACCTAAGTGAT
CTGGTTACGACAAACTTCATCAATGTAGAAGAAGAAACAAGGGAAAATATAACGATTATAGACCCAGCCAGCGATACCAT
CACAGAAATCAACTCCCAGGGCCCATTTGTGGATAAGCGGGATATCGACAAGTTCATGAAGCGTTATCTTGTCAGTTTAG
GCAGGGTAAATGCAGTCGTTATATCTGGAAGTGTTCCTCCGGGTATTCCGGAAGATTTCTACTATTTACTAGGTAACACA
GCAAAAGAAGCTGGTAAGCTCGTCGTCTCTGAATCCATTGGCGCCTGTTTTGAATATGCCGTTAAAAGAGGCGCTTTCAC
TGTTGCCAGACCAGACTTAAGAAGTGACCAGAAGCTTTTTGGGCAGGATTTAGAAGACCTGGACGATTATGTAGAAGCAG
GTAAAAAAATTGTTGAATCGGGGGCGAAAATGGCTATCCTTTCTTATGAAATCGAGGGTGATGTTATAGCCACCGAAGAA
GGCGTCTGGTTTTTCAAAACCCACGAACACGTGGAACGTTCACATCTGCTTGGGACAGGAGATAGTTTTGTTGCCGGTGT
GGTTGAACATCTGTTGAAACATCCACACGATTATCTAAATGCAGCAAAACGCGGTATGGCTGCTGCAATAACGGAAGCAG
CATATTTAGGAAAAGAAAGAATAACTTTGGACGATGTTGAAACTAACCTTACTGCTTTTGACATAAGTAGGTTGAGGTGA

Upstream 100 bases:

>100_bases
TCTAAAAAGTGGTAAAATTTTATATGCCGGAAGTACGGAAGAATTTGTGAAAGGAAGCCATTCAAGTTTCTAACGGTATC
CGGATTCGGAGGTGTGTTAC

Downstream 100 bases:

>100_bases
TTTGATGAAGGTACGCGATGCGATGATTCATGATGTATCAGCGGTTTTTGAAGATGAAACGATAGAAGATTTCATAATCA
CGTGTTTGAGAAAAATGCGC

Product: PfkB domain protein

Products: NA

Alternate protein names: Fructose 1-phosphate kinase [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MRVLTVTLNPALDRELVVENFTINNLHRVKNQKYSIMEPGGKGINVSLILSGFGIPSIAMGFIGGYIGAVVESRLRNLSD
LVTTNFINVEEETRENITIIDPASDTITEINSQGPFVDKRDIDKFMKRYLVSLGRVNAVVISGSVPPGIPEDFYYLLGNT
AKEAGKLVVSESIGACFEYAVKRGAFTVARPDLRSDQKLFGQDLEDLDDYVEAGKKIVESGAKMAILSYEIEGDVIATEE
GVWFFKTHEHVERSHLLGTGDSFVAGVVEHLLKHPHDYLNAAKRGMAAAITEAAYLGKERITLDDVETNLTAFDISRLR

Sequences:

>Translated_319_residues
MRVLTVTLNPALDRELVVENFTINNLHRVKNQKYSIMEPGGKGINVSLILSGFGIPSIAMGFIGGYIGAVVESRLRNLSD
LVTTNFINVEEETRENITIIDPASDTITEINSQGPFVDKRDIDKFMKRYLVSLGRVNAVVISGSVPPGIPEDFYYLLGNT
AKEAGKLVVSESIGACFEYAVKRGAFTVARPDLRSDQKLFGQDLEDLDDYVEAGKKIVESGAKMAILSYEIEGDVIATEE
GVWFFKTHEHVERSHLLGTGDSFVAGVVEHLLKHPHDYLNAAKRGMAAAITEAAYLGKERITLDDVETNLTAFDISRLR
>Mature_319_residues
MRVLTVTLNPALDRELVVENFTINNLHRVKNQKYSIMEPGGKGINVSLILSGFGIPSIAMGFIGGYIGAVVESRLRNLSD
LVTTNFINVEEETRENITIIDPASDTITEINSQGPFVDKRDIDKFMKRYLVSLGRVNAVVISGSVPPGIPEDFYYLLGNT
AKEAGKLVVSESIGACFEYAVKRGAFTVARPDLRSDQKLFGQDLEDLDDYVEAGKKIVESGAKMAILSYEIEGDVIATEE
GVWFFKTHEHVERSHLLGTGDSFVAGVVEHLLKHPHDYLNAAKRGMAAAITEAAYLGKERITLDDVETNLTAFDISRLR

Specific function: Unknown

COG id: COG1105

COG function: function code G; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1788493, Length=274, Percent_Identity=28.1021897810219, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1788017, Length=277, Percent_Identity=25.2707581227437, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022463
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR017583 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.56 [H]

Molecular weight: Translated: 35141; Mature: 35141

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLTVTLNPALDRELVVENFTINNLHRVKNQKYSIMEPGGKGINVSLILSGFGIPSIAM
CEEEEEEECCCCCHHHHHCCCCHHHHHHHCCCCEEEECCCCCCEEEEEEEECCCCHHHHH
GFIGGYIGAVVESRLRNLSDLVTTNFINVEEETRENITIIDPASDTITEINSQGPFVDKR
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHCCEEEECCCCHHHHHHCCCCCCCCHH
DIDKFMKRYLVSLGRVNAVVISGSVPPGIPEDFYYLLGNTAKEAGKLVVSESIGACFEYA
HHHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHCCCHHHHCCEEHHHHHHHHHHHH
VKRGAFTVARPDLRSDQKLFGQDLEDLDDYVEAGKKIVESGAKMAILSYEIEGDVIATEE
HHCCCEEEECCCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEECC
GVWFFKTHEHVERSHLLGTGDSFVAGVVEHLLKHPHDYLNAAKRGMAAAITEAAYLGKER
CEEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
ITLDDVETNLTAFDISRLR
EEEEHHHCCCEEEEHHHCC
>Mature Secondary Structure
MRVLTVTLNPALDRELVVENFTINNLHRVKNQKYSIMEPGGKGINVSLILSGFGIPSIAM
CEEEEEEECCCCCHHHHHCCCCHHHHHHHCCCCEEEECCCCCCEEEEEEEECCCCHHHHH
GFIGGYIGAVVESRLRNLSDLVTTNFINVEEETRENITIIDPASDTITEINSQGPFVDKR
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHCCEEEECCCCHHHHHHCCCCCCCCHH
DIDKFMKRYLVSLGRVNAVVISGSVPPGIPEDFYYLLGNTAKEAGKLVVSESIGACFEYA
HHHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHCCCHHHHCCEEHHHHHHHHHHHH
VKRGAFTVARPDLRSDQKLFGQDLEDLDDYVEAGKKIVESGAKMAILSYEIEGDVIATEE
HHCCCEEEECCCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEECC
GVWFFKTHEHVERSHLLGTGDSFVAGVVEHLLKHPHDYLNAAKRGMAAAITEAAYLGKER
CEEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
ITLDDVETNLTAFDISRLR
EEEEHHHCCCEEEEHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]