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The map label for this gene is hflX [H]

Identifier: 239616689

GI number: 239616689

Start: 308432

End: 309571

Strand: Direct

Name: hflX [H]

Synonym: Kole_0282

Alternate gene names: 239616689

Gene position: 308432-309571 (Clockwise)

Preceding gene: 239616688

Following gene: 239616690

Centisome position: 13.4

GC content: 39.56

Gene sequence:

>1140_bases
GTGGATAAAATCATCCAGAACCTTGATAAACCTGATAACCGCCGTTATTTTGGAAAGGGAAAGCTCGAACAGGTTAAAAA
GATAGTATCGTTCAAGAATATATCAGTCGTAATAACTCGCCATAATCTCACACCTTCCCAGAAAAAGAATCTTGAGAGTT
TTTTAGAGGTTAAGGTTCTTGACAGAACACAGGTAATTCTTGAGATCTTTAAAAAGCATGCTGTTACTAGAGAAGGAAAA
CTGGAAGTGGAACTTGCAAGGCTGAAGTACGAGCTCCCATCTTTGAAAGGAAAAGGAACCTCTCTATCAAACACTGGAGC
TGGAATAGGTACAAGAGGACCCGGTGAAAAGATACTGGAAAGAGATAGAAGATTGGCTCTGAAAAGAATAACGGTTCTCC
AAAAAGAACTTATAAAACAAAGGAAAGTACGGGAGGTTATTAGAAAGAAACGCCAACGGAATTCAATTCCCGTAGTTTCT
TTCGTGGGATATACGAATGTTGGAAAGTCTTCACTGATTTCGGCGCTAACAGGCGCTGATCTATTGGTTGAAAATCAGTT
GTTTTCTACTTTAGATGTTAAAACGTGCCGGTTGAAACTACCAAGCGGCAGAAGGGTACTAATATCTGACACGGTTGGAT
TTATAAGGGAACTCCCGCAGGAATTGATACAGTCTTTTAAATCCACCCTGGAAGAAGCAAAGTTTTCGGATTTACTCGTT
GTAGTGCTGGACGCTTCTGACCGTTATTTAGATGAGAAACTGGAGATTATCAATTCAACGTTAAGAGACATAGGTGCGGA
AAATGTTCCAAAACTGAATGTGATCAACAAAATCGACAAATGTACCGGAGAACGATTAAAGGAACTCGGGAATAGTTTTC
CTGATGCGGTCTTTGTAAGTGCTGTTTTGAAGTACAATCTCGATGAATTGAAAGAGAAAATAGATATAGTGCTCAGCCAG
AGTTTTCGGAAATACAAACTGGTTGTCCCTCCAGAAAAACTCGGCGAGTTTTTGAAGGTTCGGGATGAAATAAAAGTGAT
ATCTCAGGAATGTTATGGGGATTCGTTGATCGTTGTATATAAAGCTCCGGAAAGAATTCATAAAAAGCTCGTTTCTTTTA
TCGGGGAGGGAGTTAAATGA

Upstream 100 bases:

>100_bases
ATCGATAATTATAGCGGTTTTTAATCCAACGGAACGAAGATTAAAAGATGAGATTCTTGATGAATTAGAGGATTTAGCAG
AAACCCTTGGATATATTGTT

Downstream 100 bases:

>100_bases
AACTGCATAAACAGGTTTTGATCCTTTTACTATCATTTTTATTCCTATCCAGTTTTCTTATTGCCGGCTATCTGAAATTT
CCGTTGAATAGAAAAATTGA

Product: GTP-binding proten HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MDKIIQNLDKPDNRRYFGKGKLEQVKKIVSFKNISVVITRHNLTPSQKKNLESFLEVKVLDRTQVILEIFKKHAVTREGK
LEVELARLKYELPSLKGKGTSLSNTGAGIGTRGPGEKILERDRRLALKRITVLQKELIKQRKVREVIRKKRQRNSIPVVS
FVGYTNVGKSSLISALTGADLLVENQLFSTLDVKTCRLKLPSGRRVLISDTVGFIRELPQELIQSFKSTLEEAKFSDLLV
VVLDASDRYLDEKLEIINSTLRDIGAENVPKLNVINKIDKCTGERLKELGNSFPDAVFVSAVLKYNLDELKEKIDIVLSQ
SFRKYKLVVPPEKLGEFLKVRDEIKVISQECYGDSLIVVYKAPERIHKKLVSFIGEGVK

Sequences:

>Translated_379_residues
MDKIIQNLDKPDNRRYFGKGKLEQVKKIVSFKNISVVITRHNLTPSQKKNLESFLEVKVLDRTQVILEIFKKHAVTREGK
LEVELARLKYELPSLKGKGTSLSNTGAGIGTRGPGEKILERDRRLALKRITVLQKELIKQRKVREVIRKKRQRNSIPVVS
FVGYTNVGKSSLISALTGADLLVENQLFSTLDVKTCRLKLPSGRRVLISDTVGFIRELPQELIQSFKSTLEEAKFSDLLV
VVLDASDRYLDEKLEIINSTLRDIGAENVPKLNVINKIDKCTGERLKELGNSFPDAVFVSAVLKYNLDELKEKIDIVLSQ
SFRKYKLVVPPEKLGEFLKVRDEIKVISQECYGDSLIVVYKAPERIHKKLVSFIGEGVK
>Mature_379_residues
MDKIIQNLDKPDNRRYFGKGKLEQVKKIVSFKNISVVITRHNLTPSQKKNLESFLEVKVLDRTQVILEIFKKHAVTREGK
LEVELARLKYELPSLKGKGTSLSNTGAGIGTRGPGEKILERDRRLALKRITVLQKELIKQRKVREVIRKKRQRNSIPVVS
FVGYTNVGKSSLISALTGADLLVENQLFSTLDVKTCRLKLPSGRRVLISDTVGFIRELPQELIQSFKSTLEEAKFSDLLV
VVLDASDRYLDEKLEIINSTLRDIGAENVPKLNVINKIDKCTGERLKELGNSFPDAVFVSAVLKYNLDELKEKIDIVLSQ
SFRKYKLVVPPEKLGEFLKVRDEIKVISQECYGDSLIVVYKAPERIHKKLVSFIGEGVK

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=219, Percent_Identity=38.8127853881278, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI310133116, Length=216, Percent_Identity=39.3518518518519, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI310124269, Length=208, Percent_Identity=39.9038461538462, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI310124267, Length=208, Percent_Identity=39.9038461538462, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI310124171, Length=208, Percent_Identity=39.9038461538462, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI310124169, Length=208, Percent_Identity=39.9038461538462, Blast_Score=125, Evalue=6e-29,
Organism=Escherichia coli, GI1790615, Length=325, Percent_Identity=39.0769230769231, Blast_Score=227, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI17561038, Length=314, Percent_Identity=31.5286624203822, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24650079, Length=343, Percent_Identity=33.2361516034985, Blast_Score=132, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 42998; Mature: 42998

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIIQNLDKPDNRRYFGKGKLEQVKKIVSFKNISVVITRHNLTPSQKKNLESFLEVKVL
CCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHH
DRTQVILEIFKKHAVTREGKLEVELARLKYELPSLKGKGTSLSNTGAGIGTRGPGEKILE
HHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
RDRRLALKRITVLQKELIKQRKVREVIRKKRQRNSIPVVSFVGYTNVGKSSLISALTGAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHCCH
LLVENQLFSTLDVKTCRLKLPSGRRVLISDTVGFIRELPQELIQSFKSTLEEAKFSDLLV
HHHHHHHHHHHCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VVLDASDRYLDEKLEIINSTLRDIGAENVPKLNVINKIDKCTGERLKELGNSFPDAVFVS
EEECCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AVLKYNLDELKEKIDIVLSQSFRKYKLVVPPEKLGEFLKVRDEIKVISQECYGDSLIVVY
HHHHCCHHHHHHHHHHHHHHCHHHEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
KAPERIHKKLVSFIGEGVK
CCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDKIIQNLDKPDNRRYFGKGKLEQVKKIVSFKNISVVITRHNLTPSQKKNLESFLEVKVL
CCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHH
DRTQVILEIFKKHAVTREGKLEVELARLKYELPSLKGKGTSLSNTGAGIGTRGPGEKILE
HHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
RDRRLALKRITVLQKELIKQRKVREVIRKKRQRNSIPVVSFVGYTNVGKSSLISALTGAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHCCH
LLVENQLFSTLDVKTCRLKLPSGRRVLISDTVGFIRELPQELIQSFKSTLEEAKFSDLLV
HHHHHHHHHHHCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VVLDASDRYLDEKLEIINSTLRDIGAENVPKLNVINKIDKCTGERLKELGNSFPDAVFVS
EEECCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AVLKYNLDELKEKIDIVLSQSFRKYKLVVPPEKLGEFLKVRDEIKVISQECYGDSLIVVY
HHHHCCHHHHHHHHHHHHHHCHHHEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
KAPERIHKKLVSFIGEGVK
CCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]