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The map label for this gene is xylB [H]

Identifier: 239616570

GI number: 239616570

Start: 178672

End: 179937

Strand: Direct

Name: xylB [H]

Synonym: Kole_0162

Alternate gene names: 239616570

Gene position: 178672-179937 (Clockwise)

Preceding gene: 239616569

Following gene: 239616571

Centisome position: 7.76

GC content: 40.44

Gene sequence:

>1266_bases
ATGGTTCCTACTTTAATTCTCATAGATGAAAATGGGAAACCTCTATATAACTCAATCCAGCAAAATGACAGTAGAGCGAT
AGAAGAAATAGAATACTTCAAAAAGATGATAGACAAAGAAGTATACTTTTCCGTCACCGGAAATACAGTAAATCAGCAGG
TAATATTCCCAAAGTTTTTATGGTTGAGAAAACATGTACCTGATAAAGTCAAACACACAAGGTGGATAATGGGTTCATAT
AACTTCATAAATTTCAAACTTACAGGCATTCCCAACCTTGAAAAGAATTGGGCCCTGGAAAGTGGACTCTGGAAGATTGA
AGATGGATGGTATAAGGATATATTAGACGCTTCCGAAATTCCTGAAAGTATCCTTCCAGAAGTGTATGAACCCTGGGATA
TAGTGGGTGGAACTACCAGAGAATTAGAAGAAGAAACAGGGATTCCCGAAGGCATTCCTGTAACAGCAGGATCTGCAGAT
CATATAGCCTCCGCTCTTGCAGTTGGCATGAGCAGGAATGGTGACCTCCTCTTAAAATTCGGTGGAGCCGGAGATATATT
GTTTGTCACGGAACAATTAAAACTGAGCAAGAAGCTTTTCATTGACTACCACGATATCCCCAACTGCTATGTTCTCAACG
GCTGTATGGCATCAAGTGGAAGTATAGTGAAATGGTTTAAAAATGAGTTTGCCCCCAATGTGAACTTTGATGAACTCACC
GAAATGGCGAGAACCGCCGGAGTTGGAAGCGGTGGTATTGTCATGTTGCCATATTTCATTGGTGAGAAAACACCTATATT
TGATGCAAAAGCCAGAGGAACCATGGTAGGTCTTTCCCTTTTCCACAACAAGGGCCACATGTTTAGATCAATACTTGAGG
CGGTTGCATTTGGATTTAGGCATCACGTGGAGGTCATTGAAGAAATGGGTTTTGCCATCGAAAGAGTCTTTATGTCAAAT
GGAGGGGCTAAAAATGAGCTCTGGAGGCAGATAGTCGCAGATGTAGTGGGTTACGATGCCGTTTATATCACCAACCACCC
GGGGTCATCGCTGGGAGCCGCTTTTATAGCTGGAAAAGCAACTGGGATGTTCGAAGATTGGGACGAGATAAACAAATTTC
TAAAAACAAAAGAAAAGATATCATACGACCAAGATAATCACGAGGTTTATTCGAAATATTACGAGATATACAGAGATACA
TATACAAGTTTGAAGAGTGTTTTTGAAAAACTTTATGAAGTGTACCACGAAAAATCCGAATCTTAA

Upstream 100 bases:

>100_bases
GGTGTAACCAAAGAAAACGTAAGAGAGATACTCAACATAGCTGATGGCGCCATAATTGGTACAAGCTTGAAAAAAGATGG
AATCACAAGGCGTTTCTGGA

Downstream 100 bases:

>100_bases
AAAAGCCAGATGGGGGTATTACGATGAGCAACTGCAAAAGATTTGAGGGAATGACTGTTTTTATAACAGGAGCAGGTAAA
GGAATAGGAAAGGCAATTTC

Product: carbohydrate kinase FGGY

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MVPTLILIDENGKPLYNSIQQNDSRAIEEIEYFKKMIDKEVYFSVTGNTVNQQVIFPKFLWLRKHVPDKVKHTRWIMGSY
NFINFKLTGIPNLEKNWALESGLWKIEDGWYKDILDASEIPESILPEVYEPWDIVGGTTRELEEETGIPEGIPVTAGSAD
HIASALAVGMSRNGDLLLKFGGAGDILFVTEQLKLSKKLFIDYHDIPNCYVLNGCMASSGSIVKWFKNEFAPNVNFDELT
EMARTAGVGSGGIVMLPYFIGEKTPIFDAKARGTMVGLSLFHNKGHMFRSILEAVAFGFRHHVEVIEEMGFAIERVFMSN
GGAKNELWRQIVADVVGYDAVYITNHPGSSLGAAFIAGKATGMFEDWDEINKFLKTKEKISYDQDNHEVYSKYYEIYRDT
YTSLKSVFEKLYEVYHEKSES

Sequences:

>Translated_421_residues
MVPTLILIDENGKPLYNSIQQNDSRAIEEIEYFKKMIDKEVYFSVTGNTVNQQVIFPKFLWLRKHVPDKVKHTRWIMGSY
NFINFKLTGIPNLEKNWALESGLWKIEDGWYKDILDASEIPESILPEVYEPWDIVGGTTRELEEETGIPEGIPVTAGSAD
HIASALAVGMSRNGDLLLKFGGAGDILFVTEQLKLSKKLFIDYHDIPNCYVLNGCMASSGSIVKWFKNEFAPNVNFDELT
EMARTAGVGSGGIVMLPYFIGEKTPIFDAKARGTMVGLSLFHNKGHMFRSILEAVAFGFRHHVEVIEEMGFAIERVFMSN
GGAKNELWRQIVADVVGYDAVYITNHPGSSLGAAFIAGKATGMFEDWDEINKFLKTKEKISYDQDNHEVYSKYYEIYRDT
YTSLKSVFEKLYEVYHEKSES
>Mature_421_residues
MVPTLILIDENGKPLYNSIQQNDSRAIEEIEYFKKMIDKEVYFSVTGNTVNQQVIFPKFLWLRKHVPDKVKHTRWIMGSY
NFINFKLTGIPNLEKNWALESGLWKIEDGWYKDILDASEIPESILPEVYEPWDIVGGTTRELEEETGIPEGIPVTAGSAD
HIASALAVGMSRNGDLLLKFGGAGDILFVTEQLKLSKKLFIDYHDIPNCYVLNGCMASSGSIVKWFKNEFAPNVNFDELT
EMARTAGVGSGGIVMLPYFIGEKTPIFDAKARGTMVGLSLFHNKGHMFRSILEAVAFGFRHHVEVIEEMGFAIERVFMSN
GGAKNELWRQIVADVVGYDAVYITNHPGSSLGAAFIAGKATGMFEDWDEINKFLKTKEKISYDQDNHEVYSKYYEIYRDT
YTSLKSVFEKLYEVYHEKSES

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI41393575, Length=353, Percent_Identity=25.4957507082153, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI42794763, Length=346, Percent_Identity=25.1445086705202, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI4504007, Length=346, Percent_Identity=25.1445086705202, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI189409120, Length=346, Percent_Identity=25.1445086705202, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI88196792, Length=305, Percent_Identity=26.2295081967213, Blast_Score=76, Evalue=7e-14,
Organism=Escherichia coli, GI1789987, Length=404, Percent_Identity=25.7425742574257, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1790005, Length=416, Percent_Identity=23.7980769230769, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1787789, Length=434, Percent_Identity=24.4239631336406, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1790361, Length=389, Percent_Identity=24.6786632390745, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1789168, Length=392, Percent_Identity=21.4285714285714, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789138, Length=386, Percent_Identity=22.279792746114, Blast_Score=83, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17535599, Length=350, Percent_Identity=25.4285714285714, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24655555, Length=375, Percent_Identity=25.0666666666667, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24655560, Length=375, Percent_Identity=25.0666666666667, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24655570, Length=375, Percent_Identity=25.0666666666667, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24655574, Length=375, Percent_Identity=25.0666666666667, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24655565, Length=375, Percent_Identity=25.0666666666667, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24654573, Length=392, Percent_Identity=24.234693877551, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17864214, Length=392, Percent_Identity=24.234693877551, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24657106, Length=452, Percent_Identity=22.1238938053097, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24657102, Length=452, Percent_Identity=22.1238938053097, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356323, Length=424, Percent_Identity=21.9339622641509, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 47712; Mature: 47712

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPTLILIDENGKPLYNSIQQNDSRAIEEIEYFKKMIDKEVYFSVTGNTVNQQVIFPKFL
CCCEEEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCEEHHHHHH
WLRKHVPDKVKHTRWIMGSYNFINFKLTGIPNLEKNWALESGLWKIEDGWYKDILDASEI
HHHHCCCHHHHHHEEEEECCEEEEEEEECCCCCCCCCHHHCCCEEECCCHHHHHCCHHHC
PESILPEVYEPWDIVGGTTRELEEETGIPEGIPVTAGSADHIASALAVGMSRNGDLLLKF
CHHHHHHHCCCHHHCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEE
GGAGDILFVTEQLKLSKKLFIDYHDIPNCYVLNGCMASSGSIVKWFKNEFAPNVNFDELT
CCCCCEEEEEHHHHHCHHHEEEECCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCHHHHH
EMARTAGVGSGGIVMLPYFIGEKTPIFDAKARGTMVGLSLFHNKGHMFRSILEAVAFGFR
HHHHHCCCCCCCEEEEEHHHCCCCCCCCCCCCCCEEEHHHHHCCCHHHHHHHHHHHHHHH
HHVEVIEEMGFAIERVFMSNGGAKNELWRQIVADVVGYDAVYITNHPGSSLGAAFIAGKA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCC
TGMFEDWDEINKFLKTKEKISYDQDNHEVYSKYYEIYRDTYTSLKSVFEKLYEVYHEKSE
CCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
S
C
>Mature Secondary Structure
MVPTLILIDENGKPLYNSIQQNDSRAIEEIEYFKKMIDKEVYFSVTGNTVNQQVIFPKFL
CCCEEEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCEEHHHHHH
WLRKHVPDKVKHTRWIMGSYNFINFKLTGIPNLEKNWALESGLWKIEDGWYKDILDASEI
HHHHCCCHHHHHHEEEEECCEEEEEEEECCCCCCCCCHHHCCCEEECCCHHHHHCCHHHC
PESILPEVYEPWDIVGGTTRELEEETGIPEGIPVTAGSADHIASALAVGMSRNGDLLLKF
CHHHHHHHCCCHHHCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEE
GGAGDILFVTEQLKLSKKLFIDYHDIPNCYVLNGCMASSGSIVKWFKNEFAPNVNFDELT
CCCCCEEEEEHHHHHCHHHEEEECCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCHHHHH
EMARTAGVGSGGIVMLPYFIGEKTPIFDAKARGTMVGLSLFHNKGHMFRSILEAVAFGFR
HHHHHCCCCCCCEEEEEHHHCCCCCCCCCCCCCCEEEHHHHHCCCHHHHHHHHHHHHHHH
HHVEVIEEMGFAIERVFMSNGGAKNELWRQIVADVVGYDAVYITNHPGSSLGAAFIAGKA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCC
TGMFEDWDEINKFLKTKEKISYDQDNHEVYSKYYEIYRDTYTSLKSVFEKLYEVYHEKSE
CCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2994009 [H]