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The map label for this gene is yqiR [H]

Identifier: 239616460

GI number: 239616460

Start: 57914

End: 59626

Strand: Direct

Name: yqiR [H]

Synonym: Kole_0049

Alternate gene names: 239616460

Gene position: 57914-59626 (Clockwise)

Preceding gene: 239616459

Following gene: 239616462

Centisome position: 2.52

GC content: 46.53

Gene sequence:

>1713_bases
ATGAGTGAAAAACTTCTTGAAACCATTGTTAACGCCTTGATAGAAGCCGTAATAGTTATAGACGATTCAGAGAAAATAAT
CCTCATTAACAACGAAGCGTGCAACATTCTGAACCTCAAAAAGGATGAAGCTCTGGGGAAGCCTGTTGTTGGAACGATAC
CCAACACCAGGCTGCATATAGTCTTGAAAACCGGAAAACCTGAATACAACAGAATCCAAAAACTCGGCGATAAAACTATT
GTTACTTCACGAATACCGCTAAAAGACGAAGAAGGAAATGTTTACGCCGTCATGGCGGTCTTCAGGGATATAACAAGTAT
CAAAAGGCTGGCCGAAGAGGTTACGAACCTGCGAGAAATAGAAGCCCTCCTCTCCGCGGTCATCGACTCCACCCACGATG
CCATATCCGTCGCGGATGAAGAAGGAAAAATCGTTCTGGTGAACCGCGCTTACACGAGAATAACCGGGATGAGCGCAAAG
TATGTCATAGGAAAACTCGCGACCGTTGACATAGCTGAAGGTTCCTCTTTACACCTCGAGGTTGCGAGGCGGAAGGAACC
CATACTCAACGCCCGGTTGAAAGTAGGACCCGCTAAGAAAGATGTCGCGGTTAATGTCACTCCGTTGTTCGTGAACAACG
AATTCAAAGGAAGTGTTGCTGTTATTCACGACCTCTCCGAAATAGAAAAACTGGCAAGAGAGCTGGAACAGACAAGACGC
TTGCTGAGATACGTGAAGGCCAAATACACTTTCGATGATATAGCCGGCAACTCTCAAAAAATGCGTGTCGCTATCGAACA
GGCAAAACGCGTTGCGAAAACACCCATGACCGTTTTGCTGAGAGGACCGAGTGGAACGGGTAAAGAGCTCTTTGCCCATG
CCATCCATAACGCCAGCGATAGGGCCGATAAGAATTTTATTAGCGTGAACTGTGCCGCGCTACCGGAATCCATACTCGAG
TCAGAACTCTTTGGTTACGCCGACGGTGCTTTCACAGGTGCGAAAAAAGGCGGTAAGCGTGGGCTTCTCGAAGAAGCGAA
CAGGGGTACCCTCTTCCTCGATGAAATCGGTAAGATGAGTATCTCCGTGCAATCAAAATTCCTGCGATTCTTGCAGGATA
AGGAGATAATCCCTGTTGGCGGAACAAAACCACAAAAACTCGATGTCAGGATTATAGCCGCGACCAATTTGAATTTAGAA
CAATTGGTTGCTGAAGGAAAGTTCCTTGCCGACCTCTATTACCGTCTCAACGTAGTTCCAATAGTTATTCCGCCATTAAA
AGATCATATAGAAGATCTTCCTGAAATTGCACGGGTAATTTTGATAAGACTGAACCAGGAATACGGCAGGCTCGTCGAGG
ATATAGACGATGAAGCCCTCGAGCTCCTGATGAACTATCCCTGGCCTGGCAACGTGCGAGAACTTGAAAATGTTCTCGGG
CGTTCCATGATAAACATGGAACCGGATGAACGAGTCATCAGAAAAGACCACCTGCCGAAATTAGAACTGGAGAATCACCA
CCGCGAAGCCACTCAGATAGGGAAGCTCTCCAATCTCCTGGCAGACTACGAAAAAAAGATCATTGAAGACACCTTGAAGG
CAACCGAAGGTAACAAGACAGCAGCCGCGAAGGTTCTCGGCATAAGTATTAGATCACTTTACTACAAACTCGAAAGATAC
GGCATAGATACTGCTAAAAACTTCGAACCGTGA

Upstream 100 bases:

>100_bases
TTTCTAAGATCGCTGGGTTTTTCTGTCAACGTGAGGGCGGAGGAATTGACCATCGAAAGCTTTGTGAAACTCTATGAAGC
TTCGAAAAGGTGGAATAAGA

Downstream 100 bases:

>100_bases
TAGAATATAATTGTCTAATAAATACGGGGGCGAAACGGTCTCGACGGGGCCGTTGAACCCGTGGGAGCGAGTCGAGGTTT
CCGGTACCGCGTTAAAAAGC

Product: PAS modulated sigma54 specific transcriptional regulator, Fis family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 570; Mature: 569

Protein sequence:

>570_residues
MSEKLLETIVNALIEAVIVIDDSEKIILINNEACNILNLKKDEALGKPVVGTIPNTRLHIVLKTGKPEYNRIQKLGDKTI
VTSRIPLKDEEGNVYAVMAVFRDITSIKRLAEEVTNLREIEALLSAVIDSTHDAISVADEEGKIVLVNRAYTRITGMSAK
YVIGKLATVDIAEGSSLHLEVARRKEPILNARLKVGPAKKDVAVNVTPLFVNNEFKGSVAVIHDLSEIEKLARELEQTRR
LLRYVKAKYTFDDIAGNSQKMRVAIEQAKRVAKTPMTVLLRGPSGTGKELFAHAIHNASDRADKNFISVNCAALPESILE
SELFGYADGAFTGAKKGGKRGLLEEANRGTLFLDEIGKMSISVQSKFLRFLQDKEIIPVGGTKPQKLDVRIIAATNLNLE
QLVAEGKFLADLYYRLNVVPIVIPPLKDHIEDLPEIARVILIRLNQEYGRLVEDIDDEALELLMNYPWPGNVRELENVLG
RSMINMEPDERVIRKDHLPKLELENHHREATQIGKLSNLLADYEKKIIEDTLKATEGNKTAAAKVLGISIRSLYYKLERY
GIDTAKNFEP

Sequences:

>Translated_570_residues
MSEKLLETIVNALIEAVIVIDDSEKIILINNEACNILNLKKDEALGKPVVGTIPNTRLHIVLKTGKPEYNRIQKLGDKTI
VTSRIPLKDEEGNVYAVMAVFRDITSIKRLAEEVTNLREIEALLSAVIDSTHDAISVADEEGKIVLVNRAYTRITGMSAK
YVIGKLATVDIAEGSSLHLEVARRKEPILNARLKVGPAKKDVAVNVTPLFVNNEFKGSVAVIHDLSEIEKLARELEQTRR
LLRYVKAKYTFDDIAGNSQKMRVAIEQAKRVAKTPMTVLLRGPSGTGKELFAHAIHNASDRADKNFISVNCAALPESILE
SELFGYADGAFTGAKKGGKRGLLEEANRGTLFLDEIGKMSISVQSKFLRFLQDKEIIPVGGTKPQKLDVRIIAATNLNLE
QLVAEGKFLADLYYRLNVVPIVIPPLKDHIEDLPEIARVILIRLNQEYGRLVEDIDDEALELLMNYPWPGNVRELENVLG
RSMINMEPDERVIRKDHLPKLELENHHREATQIGKLSNLLADYEKKIIEDTLKATEGNKTAAAKVLGISIRSLYYKLERY
GIDTAKNFEP
>Mature_569_residues
SEKLLETIVNALIEAVIVIDDSEKIILINNEACNILNLKKDEALGKPVVGTIPNTRLHIVLKTGKPEYNRIQKLGDKTIV
TSRIPLKDEEGNVYAVMAVFRDITSIKRLAEEVTNLREIEALLSAVIDSTHDAISVADEEGKIVLVNRAYTRITGMSAKY
VIGKLATVDIAEGSSLHLEVARRKEPILNARLKVGPAKKDVAVNVTPLFVNNEFKGSVAVIHDLSEIEKLARELEQTRRL
LRYVKAKYTFDDIAGNSQKMRVAIEQAKRVAKTPMTVLLRGPSGTGKELFAHAIHNASDRADKNFISVNCAALPESILES
ELFGYADGAFTGAKKGGKRGLLEEANRGTLFLDEIGKMSISVQSKFLRFLQDKEIIPVGGTKPQKLDVRIIAATNLNLEQ
LVAEGKFLADLYYRLNVVPIVIPPLKDHIEDLPEIARVILIRLNQEYGRLVEDIDDEALELLMNYPWPGNVRELENVLGR
SMINMEPDERVIRKDHLPKLELENHHREATQIGKLSNLLADYEKKIIEDTLKATEGNKTAAAKVLGISIRSLYYKLERYG
IDTAKNFEP

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=335, Percent_Identity=43.8805970149254, Blast_Score=266, Evalue=3e-72,
Organism=Escherichia coli, GI1789233, Length=479, Percent_Identity=34.446764091858, Blast_Score=265, Evalue=8e-72,
Organism=Escherichia coli, GI1789087, Length=318, Percent_Identity=40.5660377358491, Blast_Score=228, Evalue=7e-61,
Organism=Escherichia coli, GI87082117, Length=327, Percent_Identity=41.5902140672783, Blast_Score=228, Evalue=1e-60,
Organism=Escherichia coli, GI1790299, Length=350, Percent_Identity=39.4285714285714, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI1788905, Length=306, Percent_Identity=42.156862745098, Blast_Score=225, Evalue=5e-60,
Organism=Escherichia coli, GI1790437, Length=308, Percent_Identity=42.8571428571429, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1786524, Length=350, Percent_Identity=35.1428571428571, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI1787583, Length=377, Percent_Identity=34.4827586206897, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI87082152, Length=302, Percent_Identity=39.4039735099338, Blast_Score=198, Evalue=9e-52,
Organism=Escherichia coli, GI87081872, Length=332, Percent_Identity=35.5421686746988, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI87081858, Length=505, Percent_Identity=26.7326732673267, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1789828, Length=281, Percent_Identity=34.5195729537367, Blast_Score=132, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR002197
- InterPro:   IPR016040
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 63573; Mature: 63442

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKLLETIVNALIEAVIVIDDSEKIILINNEACNILNLKKDEALGKPVVGTIPNTRLHI
CCHHHHHHHHHHHHHEEEEEECCCEEEEEECCCCCEEECCHHHHCCCCCEECCCCCEEEE
VLKTGKPEYNRIQKLGDKTIVTSRIPLKDEEGNVYAVMAVFRDITSIKRLAEEVTNLREI
EEECCCCHHHHHHHCCCCEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
EALLSAVIDSTHDAISVADEEGKIVLVNRAYTRITGMSAKYVIGKLATVDIAEGSSLHLE
HHHHHHHHHCCCCCEEEECCCCCEEEEECCCHHHCCCCHHHHHHEEEEEEECCCCCEEEE
VARRKEPILNARLKVGPAKKDVAVNVTPLFVNNEFKGSVAVIHDLSEIEKLARELEQTRR
EHHCCCCHHCCEEECCCCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LLRYVKAKYTFDDIAGNSQKMRVAIEQAKRVAKTPMTVLLRGPSGTGKELFAHAIHNASD
HHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCC
RADKNFISVNCAALPESILESELFGYADGAFTGAKKGGKRGLLEEANRGTLFLDEIGKMS
CCCCCEEEEEHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCCEEEEECCCCHH
ISVQSKFLRFLQDKEIIPVGGTKPQKLDVRIIAATNLNLEQLVAEGKFLADLYYRLNVVP
HHHHHHHHHHHCCCCEEECCCCCCCEEEEEEEEECCCCHHHHHHCCHHHHHHHHHHEEEE
IVIPPLKDHIEDLPEIARVILIRLNQEYGRLVEDIDDEALELLMNYPWPGNVRELENVLG
EEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHH
RSMINMEPDERVIRKDHLPKLELENHHREATQIGKLSNLLADYEKKIIEDTLKATEGNKT
HHHCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
AAAKVLGISIRSLYYKLERYGIDTAKNFEP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SEKLLETIVNALIEAVIVIDDSEKIILINNEACNILNLKKDEALGKPVVGTIPNTRLHI
CHHHHHHHHHHHHHEEEEEECCCEEEEEECCCCCEEECCHHHHCCCCCEECCCCCEEEE
VLKTGKPEYNRIQKLGDKTIVTSRIPLKDEEGNVYAVMAVFRDITSIKRLAEEVTNLREI
EEECCCCHHHHHHHCCCCEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
EALLSAVIDSTHDAISVADEEGKIVLVNRAYTRITGMSAKYVIGKLATVDIAEGSSLHLE
HHHHHHHHHCCCCCEEEECCCCCEEEEECCCHHHCCCCHHHHHHEEEEEEECCCCCEEEE
VARRKEPILNARLKVGPAKKDVAVNVTPLFVNNEFKGSVAVIHDLSEIEKLARELEQTRR
EHHCCCCHHCCEEECCCCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LLRYVKAKYTFDDIAGNSQKMRVAIEQAKRVAKTPMTVLLRGPSGTGKELFAHAIHNASD
HHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCC
RADKNFISVNCAALPESILESELFGYADGAFTGAKKGGKRGLLEEANRGTLFLDEIGKMS
CCCCCEEEEEHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCCEEEEECCCCHH
ISVQSKFLRFLQDKEIIPVGGTKPQKLDVRIIAATNLNLEQLVAEGKFLADLYYRLNVVP
HHHHHHHHHHHCCCCEEECCCCCCCEEEEEEEEECCCCHHHHHHCCHHHHHHHHHHEEEE
IVIPPLKDHIEDLPEIARVILIRLNQEYGRLVEDIDDEALELLMNYPWPGNVRELENVLG
EEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHH
RSMINMEPDERVIRKDHLPKLELENHHREATQIGKLSNLLADYEKKIIEDTLKATEGNKT
HHHCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
AAAKVLGISIRSLYYKLERYGIDTAKNFEP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]