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The map label for this gene is 238925591

Identifier: 238925591

GI number: 238925591

Start: 3085577

End: 3086632

Strand: Reverse

Name: 238925591

Synonym: EUBREC_3247

Alternate gene names: NA

Gene position: 3086632-3085577 (Counterclockwise)

Preceding gene: 238925592

Following gene: 238925590

Centisome position: 89.48

GC content: 37.22

Gene sequence:

>1056_bases
ATGTCAAAATATATAGAGGTAAATGGGAGAAGGATAGGTGAGGGGTATCCCGCCTATATTATTGCTGAGATGTCTGCAAA
TCATTTACAGGATTATGAAAGAGCTAAGAAAATTATTTCGGCGGCTAAGAAAGCAGGAGCTGATGCAATAAAACTCCAAT
CATATCGTCCTGATACAATTACTATAGATTGTCAGGGGGAAGAATTCATGGCAACCAAGGGAAGTCTTTGGGAAGGACAA
AATCTTTATCAGCTATATGAAAAAGCATATATGCCATGGGAGTGGCATGAGGGACTCTTTAAATATGCAAGGAAAATAGG
AATTGAAATTTTTTCATCCCCATTTGATTTTACAGCTGTTGATTTACTCGAAAGTCTAGATGTGCCGGTTTATAAGATTG
CATCATACGAAATTTTGGATATCCCTCTTATCAAACGCTGTGCTAGCCTTGGAAAACCTATAATACTTTCTACTGGCATT
GCAACATTAGCAGATATAGAGAGGGCGGTTGAAGCATGTAAATCTGTTGGAAATAATGACATTGCGATTTTGAAATGTGT
ATCGCAATATCCAGCTCCATATAAGGATTTGAACCTTAGGACAATACCACATATGGCAGAGACATTCGACTGCATTACGG
GACTTTCTGATCATTCAATGGGGTCTGCAGTTGATGTCTGTGCTGTTTCAATAGGGGCTCATATAATTGAAAAACATATG
ACCCTACGACGTTCGGATGGTGGACCTGATGGTGCTTTTTCAATGGAACCTGAAGAATTTGCTGCTATGGTTGAAGATAT
CCATAATGTAGAAAATGCTTTAGGTGTGGTAACTTATAATTTAACTGAAGTTCAAAAAAATGGCAAGAAACATGCTAGAT
CTCTTTATGTAGTTAGTGATATTAAAGCAGGAGAGACTTTTACAAAAGATAATGTGAAATCCATTCGCCCAGGGTGTGGT
CTTAGTACTTGGTATTATGATGAAATAATAGGGAAAAAAGCTATGGTTGATATCAAGAAAGGAACTGCAATGGCATGGAA
ATATGTAAAAAAATAA

Upstream 100 bases:

>100_bases
TGCCGATTGAATTACCTGAATTAGAGGTTCAGGATATTGATAATGAGCAAGACTGGATTATAGCGGAAATGAAGTATAAG
CTCATGAAAGGGGAAACAAA

Downstream 100 bases:

>100_bases
TGAAGGAATAGGATATGTTTTTTATAAGAGTTGACAGTAATCAAACCATATCTGGTGGACATATTATGCGATGTCTAGCC
ATAGCCAAAGCATTGATTAT

Product: sialic acid synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MSKYIEVNGRRIGEGYPAYIIAEMSANHLQDYERAKKIISAAKKAGADAIKLQSYRPDTITIDCQGEEFMATKGSLWEGQ
NLYQLYEKAYMPWEWHEGLFKYARKIGIEIFSSPFDFTAVDLLESLDVPVYKIASYEILDIPLIKRCASLGKPIILSTGI
ATLADIERAVEACKSVGNNDIAILKCVSQYPAPYKDLNLRTIPHMAETFDCITGLSDHSMGSAVDVCAVSIGAHIIEKHM
TLRRSDGGPDGAFSMEPEEFAAMVEDIHNVENALGVVTYNLTEVQKNGKKHARSLYVVSDIKAGETFTKDNVKSIRPGCG
LSTWYYDEIIGKKAMVDIKKGTAMAWKYVKK

Sequences:

>Translated_351_residues
MSKYIEVNGRRIGEGYPAYIIAEMSANHLQDYERAKKIISAAKKAGADAIKLQSYRPDTITIDCQGEEFMATKGSLWEGQ
NLYQLYEKAYMPWEWHEGLFKYARKIGIEIFSSPFDFTAVDLLESLDVPVYKIASYEILDIPLIKRCASLGKPIILSTGI
ATLADIERAVEACKSVGNNDIAILKCVSQYPAPYKDLNLRTIPHMAETFDCITGLSDHSMGSAVDVCAVSIGAHIIEKHM
TLRRSDGGPDGAFSMEPEEFAAMVEDIHNVENALGVVTYNLTEVQKNGKKHARSLYVVSDIKAGETFTKDNVKSIRPGCG
LSTWYYDEIIGKKAMVDIKKGTAMAWKYVKK
>Mature_350_residues
SKYIEVNGRRIGEGYPAYIIAEMSANHLQDYERAKKIISAAKKAGADAIKLQSYRPDTITIDCQGEEFMATKGSLWEGQN
LYQLYEKAYMPWEWHEGLFKYARKIGIEIFSSPFDFTAVDLLESLDVPVYKIASYEILDIPLIKRCASLGKPIILSTGIA
TLADIERAVEACKSVGNNDIAILKCVSQYPAPYKDLNLRTIPHMAETFDCITGLSDHSMGSAVDVCAVSIGAHIIEKHMT
LRRSDGGPDGAFSMEPEEFAAMVEDIHNVENALGVVTYNLTEVQKNGKKHARSLYVVSDIKAGETFTKDNVKSIRPGCGL
STWYYDEIIGKKAMVDIKKGTAMAWKYVKK

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=336, Percent_Identity=30.6547619047619, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI21357081, Length=256, Percent_Identity=32.8125, Blast_Score=141, Evalue=7e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 39035; Mature: 38904

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKYIEVNGRRIGEGYPAYIIAEMSANHLQDYERAKKIISAAKKAGADAIKLQSYRPDTI
CCCEEEECCEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEE
TIDCQGEEFMATKGSLWEGQNLYQLYEKAYMPWEWHEGLFKYARKIGIEIFSSPFDFTAV
EEEECCCCEECCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHH
DLLESLDVPVYKIASYEILDIPLIKRCASLGKPIILSTGIATLADIERAVEACKSVGNND
HHHHHCCCCEEEECCCEEECCHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHCCCCC
IAILKCVSQYPAPYKDLNLRTIPHMAETFDCITGLSDHSMGSAVDVCAVSIGAHIIEKHM
CCEEEEHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
TLRRSDGGPDGAFSMEPEEFAAMVEDIHNVENALGVVTYNLTEVQKNGKKHARSLYVVSD
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHCHHHHHHEEEEEEE
IKAGETFTKDNVKSIRPGCGLSTWYYDEIIGKKAMVDIKKGTAMAWKYVKK
CCCCCCCCCCCHHHCCCCCCCCHHHHHHHHCCHHEEEECCCCHHHHHHHCC
>Mature Secondary Structure 
SKYIEVNGRRIGEGYPAYIIAEMSANHLQDYERAKKIISAAKKAGADAIKLQSYRPDTI
CCEEEECCEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEE
TIDCQGEEFMATKGSLWEGQNLYQLYEKAYMPWEWHEGLFKYARKIGIEIFSSPFDFTAV
EEEECCCCEECCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHH
DLLESLDVPVYKIASYEILDIPLIKRCASLGKPIILSTGIATLADIERAVEACKSVGNND
HHHHHCCCCEEEECCCEEECCHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHCCCCC
IAILKCVSQYPAPYKDLNLRTIPHMAETFDCITGLSDHSMGSAVDVCAVSIGAHIIEKHM
CCEEEEHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
TLRRSDGGPDGAFSMEPEEFAAMVEDIHNVENALGVVTYNLTEVQKNGKKHARSLYVVSD
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHCHHHHHHEEEEEEE
IKAGETFTKDNVKSIRPGCGLSTWYYDEIIGKKAMVDIKKGTAMAWKYVKK
CCCCCCCCCCCHHHCCCCCCCCHHHHHHHHCCHHEEEECCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]