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The map label for this gene is csd [H]

Identifier: 238925504

GI number: 238925504

Start: 3011183

End: 3012346

Strand: Reverse

Name: csd [H]

Synonym: EUBREC_3160

Alternate gene names: 238925504

Gene position: 3012346-3011183 (Counterclockwise)

Preceding gene: 238925505

Following gene: 238925503

Centisome position: 87.32

GC content: 46.91

Gene sequence:

>1164_bases
ATGATTTACCTGGACAATGCTGCCACAACAATTAAAAAGCCGGATGCGGTATATGATGCAGTGCTTGATGCAATGAAGCA
CTGCGGCAATTCCGGGCGCGGGGCATCGGATGCATCGCTTGATGCGTCGAGGAAAATATATGAGGCCAGAATGTGCCTTG
CAGAATTTTTCGGCGGAGATGATGCGGCCAGACTCGTTTTTACGGCAAATGCCACTGAGGCACTAAACATTGCAATCCAC
GGACTGTTTGAGCCGGGGGAGCATGTGATTACAACACAGCTCGAGCATAATTCCGTGCTCAGACCTCTTTATATGCAAAG
GGAGCGGGGCGTGGGTGTGGATATTGTACCATGCAGTGATGCAGGCATAAAAAGGGGGATAATTTCCCCATCGGACATAG
AGGCTTTAATCCGTCCGGATACAAAAGCCATCGTATGCACACATGCTTCAAATCTCACAGGCAACGTGGTGGATATTAAG
TCGATAGGTCAAATCGCACGAAAGTATAACCTTTTATTTATAGTCGATGCATCGCAGACAGCCGGTGTACTTCCTATAAA
TATAAGGGAAATGAATATTGATGTGCTCTGCTTCACAGGCCATAAGGGTTTGATGGGACCGCAGGGCACCGGAGGCCTTT
ATGTGGGAGAGAGAGCAGATATAAAGCCGTTTAAGAGCGGTGGCACCGGCGTGCTAAGCTTTCTTGAGAACCAGCCTATG
GAGCTTCCGACAAGACTTGAGGCCGGTACCTTAAACGGTCCGGGAATCGCAGGGCTTTTAACTGGTGTCATGGAGCTTGA
GAAAATCGGCCTCGACAATATATACGCTAAAGAGCATGAGCTGATGCAGGCATTTATGGGAAAAATAAAGACAATCCCGG
GAATCAGGATATATGGAGATTTCGATGTGCTGTCCGACAATGGTCTGCACTGTGCGATTGTTTCTGTAAATATAGCTGAT
ATGGACTCGGCGGAGGTGTCAGACATACTTATGAATGAGTATGGCATAGCAACAAGGAGCGGTATACACTGCGCACCACT
GATGCATAAATTCTTTGGAACACAAAAACAGGGTATGGTGAGATTCTCATTTTCATATTATAATACAGTTGATGAGATAA
ATGAGGCCGCTGAAGCGCTTATGCAGATTGCGGCATTGCGATAA

Upstream 100 bases:

>100_bases
CGAGGCATACAGAAGCAAATATGCTTAACAAAAATATAAATGATGAGCTTTATATAAAGAATTTTTATCTGCTTGGATGA
GAAGTAAATGAGGACATACT

Downstream 100 bases:

>100_bases
ATAGTATTAAACAATTGAAAGGAGCAAAAATGCCACAGGAAATAGTGTTTTGCAAGGGCGGTGGCTGTACCGCAAAGCTT
GGTCCGGATTTGTTAAGTCA

Product: cysteine desulfurase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MIYLDNAATTIKKPDAVYDAVLDAMKHCGNSGRGASDASLDASRKIYEARMCLAEFFGGDDAARLVFTANATEALNIAIH
GLFEPGEHVITTQLEHNSVLRPLYMQRERGVGVDIVPCSDAGIKRGIISPSDIEALIRPDTKAIVCTHASNLTGNVVDIK
SIGQIARKYNLLFIVDASQTAGVLPINIREMNIDVLCFTGHKGLMGPQGTGGLYVGERADIKPFKSGGTGVLSFLENQPM
ELPTRLEAGTLNGPGIAGLLTGVMELEKIGLDNIYAKEHELMQAFMGKIKTIPGIRIYGDFDVLSDNGLHCAIVSVNIAD
MDSAEVSDILMNEYGIATRSGIHCAPLMHKFFGTQKQGMVRFSFSYYNTVDEINEAAEALMQIAALR

Sequences:

>Translated_387_residues
MIYLDNAATTIKKPDAVYDAVLDAMKHCGNSGRGASDASLDASRKIYEARMCLAEFFGGDDAARLVFTANATEALNIAIH
GLFEPGEHVITTQLEHNSVLRPLYMQRERGVGVDIVPCSDAGIKRGIISPSDIEALIRPDTKAIVCTHASNLTGNVVDIK
SIGQIARKYNLLFIVDASQTAGVLPINIREMNIDVLCFTGHKGLMGPQGTGGLYVGERADIKPFKSGGTGVLSFLENQPM
ELPTRLEAGTLNGPGIAGLLTGVMELEKIGLDNIYAKEHELMQAFMGKIKTIPGIRIYGDFDVLSDNGLHCAIVSVNIAD
MDSAEVSDILMNEYGIATRSGIHCAPLMHKFFGTQKQGMVRFSFSYYNTVDEINEAAEALMQIAALR
>Mature_387_residues
MIYLDNAATTIKKPDAVYDAVLDAMKHCGNSGRGASDASLDASRKIYEARMCLAEFFGGDDAARLVFTANATEALNIAIH
GLFEPGEHVITTQLEHNSVLRPLYMQRERGVGVDIVPCSDAGIKRGIISPSDIEALIRPDTKAIVCTHASNLTGNVVDIK
SIGQIARKYNLLFIVDASQTAGVLPINIREMNIDVLCFTGHKGLMGPQGTGGLYVGERADIKPFKSGGTGVLSFLENQPM
ELPTRLEAGTLNGPGIAGLLTGVMELEKIGLDNIYAKEHELMQAFMGKIKTIPGIRIYGDFDVLSDNGLHCAIVSVNIAD
MDSAEVSDILMNEYGIATRSGIHCAPLMHKFFGTQKQGMVRFSFSYYNTVDEINEAAEALMQIAALR

Specific function: Cysteine Desulfurases Mobilize The Sulfur From L- Cysteine To Yield L-Alanine, An Essential Step In Sulfur Metabolism For Biosynthesis Of A Variety Of Sulfur-Containing Biomolecules. Component Of The Suf Operon, Which Is Activated And Required Under Speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=398, Percent_Identity=26.3819095477387, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI156713448, Length=293, Percent_Identity=28.3276450511945, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1787970, Length=398, Percent_Identity=28.894472361809, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1789175, Length=386, Percent_Identity=28.2383419689119, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI48994898, Length=415, Percent_Identity=28.1927710843373, Blast_Score=120, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI25143064, Length=227, Percent_Identity=31.7180616740088, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17533177, Length=197, Percent_Identity=30.9644670050761, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI193211090, Length=417, Percent_Identity=25.1798561151079, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319831, Length=269, Percent_Identity=31.5985130111524, Blast_Score=109, Evalue=8e-25,
Organism=Drosophila melanogaster, GI20129463, Length=399, Percent_Identity=26.3157894736842, Blast_Score=110, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 41788; Mature: 41788

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYLDNAATTIKKPDAVYDAVLDAMKHCGNSGRGASDASLDASRKIYEARMCLAEFFGGD
CEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
DAARLVFTANATEALNIAIHGLFEPGEHVITTQLEHNSVLRPLYMQRERGVGVDIVPCSD
CCEEEEEEECCCCEEEEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEECCC
AGIKRGIISPSDIEALIRPDTKAIVCTHASNLTGNVVDIKSIGQIARKYNLLFIVDASQT
CCCCCCCCCCCCCHHEECCCCCEEEEEECCCCCCCEEEHHHHHHHHHHCCEEEEEECCCC
AGVLPINIREMNIDVLCFTGHKGLMGPQGTGGLYVGERADIKPFKSGGTGVLSFLENQPM
CCEEEEEEEEEEEEEEEEECCCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHCCCCC
ELPTRLEAGTLNGPGIAGLLTGVMELEKIGLDNIYAKEHELMQAFMGKIKTIPGIRIYGD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEC
FDVLSDNGLHCAIVSVNIADMDSAEVSDILMNEYGIATRSGIHCAPLMHKFFGTQKQGMV
EEEECCCCCEEEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCEE
RFSFSYYNTVDEINEAAEALMQIAALR
EEEEHHHCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIYLDNAATTIKKPDAVYDAVLDAMKHCGNSGRGASDASLDASRKIYEARMCLAEFFGGD
CEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
DAARLVFTANATEALNIAIHGLFEPGEHVITTQLEHNSVLRPLYMQRERGVGVDIVPCSD
CCEEEEEEECCCCEEEEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEECCC
AGIKRGIISPSDIEALIRPDTKAIVCTHASNLTGNVVDIKSIGQIARKYNLLFIVDASQT
CCCCCCCCCCCCCHHEECCCCCEEEEEECCCCCCCEEEHHHHHHHHHHCCEEEEEECCCC
AGVLPINIREMNIDVLCFTGHKGLMGPQGTGGLYVGERADIKPFKSGGTGVLSFLENQPM
CCEEEEEEEEEEEEEEEEECCCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHCCCCC
ELPTRLEAGTLNGPGIAGLLTGVMELEKIGLDNIYAKEHELMQAFMGKIKTIPGIRIYGD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEC
FDVLSDNGLHCAIVSVNIADMDSAEVSDILMNEYGIATRSGIHCAPLMHKFFGTQKQGMV
EEEECCCCCEEEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCEE
RFSFSYYNTVDEINEAAEALMQIAALR
EEEEHHHCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]