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The map label for this gene is lepB [H]

Identifier: 238925467

GI number: 238925467

Start: 2977728

End: 2978369

Strand: Reverse

Name: lepB [H]

Synonym: EUBREC_3122

Alternate gene names: 238925467

Gene position: 2978369-2977728 (Counterclockwise)

Preceding gene: 238925468

Following gene: 238925466

Centisome position: 86.34

GC content: 44.39

Gene sequence:

>642_bases
ATGAATAAGGAGAACATGAAAATGGAGATATTAGACTTAAACAACGAAGAAGACACAAAAACAACCGATGAGATGGAGCC
AAAAAAGCCGGAGGAAAAAACATCACCTGTCAAGGAAATCTTAAGCTGGGTGTTAACAATCGCATTCGCCATTGTAGCGG
CAATACTCATAAAGAACTATGTCATTATAAATGCAAATATTCCGTCAGGCTCGATGGAGAACACCATACAGATTGGAGAT
GACATATTTGGCTTCAGGCTCGCATATACATTTTCTGACCCAAAGAGAGGGGACATAGTCATATTCAATGCGCCGGATTC
GCCTTCTGAGAAATACATCAAGCGTGTAATAGGTCTGCCGGGAGAGACAGTCACCATAGAGGACGGCAAGGTGTATATAG
ATGGTGAGGCGCTTGAGGAGGATTATCTCAAGTCAAACCAGAGCGGTGAGGATGCGTGGACAGTAAATGCCGGACCTTAC
GAGTTTAAGGTGCCACAGGACTCATATCTGCTGCTCGGTGACAACAGAAATGGCTCATCAGACGCAAGAGTCTGGGAGCA
CACATATGTGTCCAAGGACGATATACTTGCAAAAGCGATATTCAGATATTACCCGTTCGACAGATTCGGAGCGGTGAAAT
AA

Upstream 100 bases:

>100_bases
GCTTACAAGTCTTTATTTTACAAGGAAGGACTTTATAAAGTGGTGGATGGCACCATAGGTTGTACCGCCATGACATATAT
TATCAAACACTTATTGAAGC

Downstream 100 bases:

>100_bases
GCTGTAAATCAGGATATAAAATAAAAATAGAGGTAAAGTAAATGCCAAAGACAGAAACAGACATTGAAAAACGAAATAAA
TATGGCATGCTGTGCGGTAT

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MNKENMKMEILDLNNEEDTKTTDEMEPKKPEEKTSPVKEILSWVLTIAFAIVAAILIKNYVIINANIPSGSMENTIQIGD
DIFGFRLAYTFSDPKRGDIVIFNAPDSPSEKYIKRVIGLPGETVTIEDGKVYIDGEALEEDYLKSNQSGEDAWTVNAGPY
EFKVPQDSYLLLGDNRNGSSDARVWEHTYVSKDDILAKAIFRYYPFDRFGAVK

Sequences:

>Translated_213_residues
MNKENMKMEILDLNNEEDTKTTDEMEPKKPEEKTSPVKEILSWVLTIAFAIVAAILIKNYVIINANIPSGSMENTIQIGD
DIFGFRLAYTFSDPKRGDIVIFNAPDSPSEKYIKRVIGLPGETVTIEDGKVYIDGEALEEDYLKSNQSGEDAWTVNAGPY
EFKVPQDSYLLLGDNRNGSSDARVWEHTYVSKDDILAKAIFRYYPFDRFGAVK
>Mature_213_residues
MNKENMKMEILDLNNEEDTKTTDEMEPKKPEEKTSPVKEILSWVLTIAFAIVAAILIKNYVIINANIPSGSMENTIQIGD
DIFGFRLAYTFSDPKRGDIVIFNAPDSPSEKYIKRVIGLPGETVTIEDGKVYIDGEALEEDYLKSNQSGEDAWTVNAGPY
EFKVPQDSYLLLGDNRNGSSDARVWEHTYVSKDDILAKAIFRYYPFDRFGAVK

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=139, Percent_Identity=35.9712230215827, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 24063; Mature: 24063

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: PS00760 SPASE_I_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKENMKMEILDLNNEEDTKTTDEMEPKKPEEKTSPVKEILSWVLTIAFAIVAAILIKNY
CCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCE
VIINANIPSGSMENTIQIGDDIFGFRLAYTFSDPKRGDIVIFNAPDSPSEKYIKRVIGLP
EEEECCCCCCCCCCEEEECCCEEEEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHCCC
GETVTIEDGKVYIDGEALEEDYLKSNQSGEDAWTVNAGPYEFKVPQDSYLLLGDNRNGSS
CCEEEEECCEEEECCCHHHHHHHHCCCCCCCEEEECCCCEEEECCCCCEEEEECCCCCCC
DARVWEHTYVSKDDILAKAIFRYYPFDRFGAVK
CCEEEHHHCCCHHHHHHHHHHHHCCCHHCCCCC
>Mature Secondary Structure
MNKENMKMEILDLNNEEDTKTTDEMEPKKPEEKTSPVKEILSWVLTIAFAIVAAILIKNY
CCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCE
VIINANIPSGSMENTIQIGDDIFGFRLAYTFSDPKRGDIVIFNAPDSPSEKYIKRVIGLP
EEEECCCCCCCCCCEEEECCCEEEEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHCCC
GETVTIEDGKVYIDGEALEEDYLKSNQSGEDAWTVNAGPYEFKVPQDSYLLLGDNRNGSS
CCEEEEECCEEEECCCHHHHHHHHCCCCCCCEEEECCCCEEEECCCCCEEEEECCCCCCC
DARVWEHTYVSKDDILAKAIFRYYPFDRFGAVK
CCEEEHHHCCCHHHHHHHHHHHHCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7865790 [H]