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The map label for this gene is vanYB [H]

Identifier: 238925453

GI number: 238925453

Start: 2968495

End: 2968932

Strand: Reverse

Name: vanYB [H]

Synonym: EUBREC_3108

Alternate gene names: 238925453

Gene position: 2968932-2968495 (Counterclockwise)

Preceding gene: 238925454

Following gene: 238925452

Centisome position: 86.06

GC content: 39.27

Gene sequence:

>438_bases
TTGAAAACAAAATTGTTTGCAGGCAGCAAAAGGGGGACTCTTTTTGCTGCCTTTTTGCGGGCTGTTTCGTATATAGCGAT
TCAGGGTGAAATTCCAATGATTAATAGTTTCAATCTATTTAGAAGAGAAGCAGATACTTCTTTTGGGTGGAATCTGATTC
TTGTAAATGACGATTATCGTATTCCTCGTAATTATGAGGTAGAACTCACAGAATTATCAAATGGAGAAAAAGTGGATTCG
AGAATCTATCCTCAGCTTCAGCAGATGTTCGATGATGCCAGAACTGAGGGACTTGAATTATTTGTAAGGGAAGGGTACAG
GACAACCCAGGATCAGAAAAATATTATGAATGAGAGAATTCAAAAGTATCAGGATGAAGGCTATTCACGTTGGGAGGCAA
AAGAACGTGCGGAGGAATATATCGAGTCACTGAGGTGA

Upstream 100 bases:

>100_bases
ATGTATATACCAATTTATATGACTATGTTACTGTAAGACGATTAGTCGGAATGAACTCATTTTTTTTCATTTTGTCAAGT
ACAAGCTTGATACCATTAAA

Downstream 100 bases:

>100_bases
AAATTATAAAAAATTAAATGAATATTAATTTTCCACTAACTTTTTATCACCTTAAGTTGTCTTATTATTATAGAGGACAA
GAGAGGTGATATGAGATGAT

Product: D-alanyl-D-alanine carboxypeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase [H]

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MKTKLFAGSKRGTLFAAFLRAVSYIAIQGEIPMINSFNLFRREADTSFGWNLILVNDDYRIPRNYEVELTELSNGEKVDS
RIYPQLQQMFDDARTEGLELFVREGYRTTQDQKNIMNERIQKYQDEGYSRWEAKERAEEYIESLR

Sequences:

>Translated_145_residues
MKTKLFAGSKRGTLFAAFLRAVSYIAIQGEIPMINSFNLFRREADTSFGWNLILVNDDYRIPRNYEVELTELSNGEKVDS
RIYPQLQQMFDDARTEGLELFVREGYRTTQDQKNIMNERIQKYQDEGYSRWEAKERAEEYIESLR
>Mature_145_residues
MKTKLFAGSKRGTLFAAFLRAVSYIAIQGEIPMINSFNLFRREADTSFGWNLILVNDDYRIPRNYEVELTELSNGEKVDS
RIYPQLQQMFDDARTEGLELFVREGYRTTQDQKNIMNERIQKYQDEGYSRWEAKERAEEYIESLR

Specific function: Vancomycin-inducible, penicillin-resistant, DD- carboxypeptidase that hydrolyzes depsipeptide- and D-alanyl-D- alanine-containing peptidoglycan precursors. Insensitive to beta- lactams [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M15B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009045
- InterPro:   IPR003709 [H]

Pfam domain/function: PF02557 VanY [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 17184; Mature: 17184

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKLFAGSKRGTLFAAFLRAVSYIAIQGEIPMINSFNLFRREADTSFGWNLILVNDDYR
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCEEEEECCCCC
IPRNYEVELTELSNGEKVDSRIYPQLQQMFDDARTEGLELFVREGYRTTQDQKNIMNERI
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
QKYQDEGYSRWEAKERAEEYIESLR
HHHHHCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTKLFAGSKRGTLFAAFLRAVSYIAIQGEIPMINSFNLFRREADTSFGWNLILVNDDYR
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCEEEEECCCCC
IPRNYEVELTELSNGEKVDSRIYPQLQQMFDDARTEGLELFVREGYRTTQDQKNIMNERI
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
QKYQDEGYSRWEAKERAEEYIESLR
HHHHHCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8631706; 12663927 [H]