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The map label for this gene is gntR [H]

Identifier: 238925428

GI number: 238925428

Start: 2948412

End: 2949056

Strand: Reverse

Name: gntR [H]

Synonym: EUBREC_3083

Alternate gene names: 238925428

Gene position: 2949056-2948412 (Counterclockwise)

Preceding gene: 238925429

Following gene: 238925427

Centisome position: 85.49

GC content: 44.5

Gene sequence:

>645_bases
ATGATAGGACTTAAACCGATAAAGATTCCGTCAGCGAAGGAGCGTGTAGCATCGGAGCTGCGCAAGGCAATTTTGTCAAA
ACAGCTAAAAGAGGGAGAAAATCTTACACTGGAAAATGTAGCGCAGCAGCTTAATGTATCTATAACTCCCGTGCGTGAGG
CTTTTCAGATATTAGCGCATGACGGACTTATCAAGCTAAGACCGAATAAGGGAGCAATAGTACTTGGAATTACAGAGACG
TACATAAGGGAGCACTATCAGATTAGAGGTATACTCGAGGGCGCATGTGCAGGTTTTGCTGCTTCACCTGATATCGATAT
CAGCAAGATAGAGCAGTCATACCTGGATGCAAGGGAGATGACAGCTTCCGGAGATTATAGCAGATATGCGGATTTAAACC
GTGAGTTTCATAGTGAAATCTGGGCAGCATCCGGCAATAAAAAGATGGAAAATATGATCGCAGAACTGTGGAACGGACTT
TCAATGGGCAGCATGGTCACAGAGGAGGAATATGCGGGCATTTCTATAAAGGAGCATGAGGCTATATACGAAGCAATCAA
GGCTCATGATGTGCAGCTTGCACAGCGGAGGATGTATGAGCATATCATGCGTAGTCGTGATGATATGCTGACATATTATG
TGTAG

Upstream 100 bases:

>100_bases
GAAGAAAGCAGCAGGTAATTGGTGACTTATTTTATACTGAATAATGACAGATGATTCGGAAGCATATAAAATTAAAAGAT
AACAAGAGGAAAAAGTAATT

Downstream 100 bases:

>100_bases
ATATAAGTTACTAATTTAACACATTACTTGTAATAGATGCACAAATTGAATAGGTGGAATATATATAAATTGCCGAAATT
GTCAAAAAGGTATTGACGAT

Product: hypothetical protein

Products: NA

Alternate protein names: P28 protein [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MIGLKPIKIPSAKERVASELRKAILSKQLKEGENLTLENVAQQLNVSITPVREAFQILAHDGLIKLRPNKGAIVLGITET
YIREHYQIRGILEGACAGFAASPDIDISKIEQSYLDAREMTASGDYSRYADLNREFHSEIWAASGNKKMENMIAELWNGL
SMGSMVTEEEYAGISIKEHEAIYEAIKAHDVQLAQRRMYEHIMRSRDDMLTYYV

Sequences:

>Translated_214_residues
MIGLKPIKIPSAKERVASELRKAILSKQLKEGENLTLENVAQQLNVSITPVREAFQILAHDGLIKLRPNKGAIVLGITET
YIREHYQIRGILEGACAGFAASPDIDISKIEQSYLDAREMTASGDYSRYADLNREFHSEIWAASGNKKMENMIAELWNGL
SMGSMVTEEEYAGISIKEHEAIYEAIKAHDVQLAQRRMYEHIMRSRDDMLTYYV
>Mature_214_residues
MIGLKPIKIPSAKERVASELRKAILSKQLKEGENLTLENVAQQLNVSITPVREAFQILAHDGLIKLRPNKGAIVLGITET
YIREHYQIRGILEGACAGFAASPDIDISKIEQSYLDAREMTASGDYSRYADLNREFHSEIWAASGNKKMENMIAELWNGL
SMGSMVTEEEYAGISIKEHEAIYEAIKAHDVQLAQRRMYEHIMRSRDDMLTYYV

Specific function: Transcriptional repressor of the gluconate operon (gntRKPZ), which encodes the proteins for gluconate utilization. Represses mRNA synthesis by binding to the gnt operator; the binding is suppressed by gluconate or glucono-delta-lactone [H]

COG id: COG1802

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 24206; Mature: 24206

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGLKPIKIPSAKERVASELRKAILSKQLKEGENLTLENVAQQLNVSITPVREAFQILAH
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHC
DGLIKLRPNKGAIVLGITETYIREHYQIRGILEGACAGFAASPDIDISKIEQSYLDAREM
CCEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
TASGDYSRYADLNREFHSEIWAASGNKKMENMIAELWNGLSMGSMVTEEEYAGISIKEHE
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHCHHHHCCCCHHHHH
AIYEAIKAHDVQLAQRRMYEHIMRSRDDMLTYYV
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEECC
>Mature Secondary Structure
MIGLKPIKIPSAKERVASELRKAILSKQLKEGENLTLENVAQQLNVSITPVREAFQILAH
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHC
DGLIKLRPNKGAIVLGITETYIREHYQIRGILEGACAGFAASPDIDISKIEQSYLDAREM
CCEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
TASGDYSRYADLNREFHSEIWAASGNKKMENMIAELWNGLSMGSMVTEEEYAGISIKEHE
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHCHHHHCCCCHHHHH
AIYEAIKAHDVQLAQRRMYEHIMRSRDDMLTYYV
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3020045; 7584049; 9384377; 2419835; 8510140 [H]