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The map label for this gene is bdhA [H]

Identifier: 238925392

GI number: 238925392

Start: 2918644

End: 2919801

Strand: Reverse

Name: bdhA [H]

Synonym: EUBREC_3047

Alternate gene names: 238925392

Gene position: 2919801-2918644 (Counterclockwise)

Preceding gene: 238925393

Following gene: 238925390

Centisome position: 84.64

GC content: 46.03

Gene sequence:

>1158_bases
ATGTACAATTTTACATTCAACATTCCAACAAAGATTCATTTCGGAAAGGATACCATTTCGAGCTTATCAGAGCTCAAGGC
ATATGGCAGCAAGGTGCTTTTGGTGTACGGAGGCGGCTCTATAAAGAAAAACGGTCTCTACGATACCGCAATGAAAATCC
TTAAGGATGCGGGGCTGACCGTGTTTGAGCTTAGCGGAGTGGAGCCAAACCCAAAGATTGAGACAGTCAGAAAGGGTGTT
GAAATCTGTAAAAATGAGGGTATCGACATGGTGCTTGCAATAGGTGGCGGCAGTACAATCGATTGCTCAAAGGTTGTTGC
AGCAGGTGCAAAGTATGATGGTGATGCATGGGATTTGGTGCTTGATGGCTCGAAGGTCAAGGCGGCACTTCCGATATTTG
ATGTGCTTACTCTTTCCGCAACCGGAACAGAGATGGATCCTTTTGCTGTTATCTCTGATATGTCTAAAAATGAAAAGTGG
GGAACAGGATCGCCGTATATGGTGCCAACTATGTCAATATTAAATCCTGAATATACTTTTTCGGTATCAAAAAAACAGAC
TGCAGCAGGAACCGCAGATATGATGAGCCATACAATGGAGAATTATTTTTCTATGGAGAATGCTGACTGCCAGAAATTTA
TGGCAGAGGGATTGTTACGTACAATGATTAAAAATGGACCGGTTGCCCTCGCACAGCCTGACAACTACGAGGCCAGAGCC
AACCTGATGTGGGCAGGCACCCATGCAATCAACGGTGTTGTGGGTGACGGCTGTTCACCGGCATGGTGCGTACATCCTAT
GGAGCATGAGCTGAGCGCTTTCTATGATATTACCCACGGAGAGGGACTTGCAATACTCACACCGGCGTGGATGGAGCACA
TACTAAATGACGACACACTTCCGATGTTTGTGGAGTTTGCAAAAAATGTCTGGGGACTTTCCGGTGATGATGACTATGCA
CTTGCACACGCAGGCATTGATGCACTGAAGAAATTCTTCTTTGAGACAATGGGCATTCCGGCAAATCTAAGAGCTGTGGG
AATCACAGACGACAGGAACTTTGAGGTGATGGCAAAGAAGGCCTGCGAGGGTTCAAAGGGATCGTTTGTACCGCTTAGCA
AGGACGATATTGTGGAGATTTACAGAGCAGCATTCTAA

Upstream 100 bases:

>100_bases
TGATGCGCTGATTGAAAATTTTGACAAGGCTTTATCACATCCTGATTCAGATGATTTGGAGAGATTAAAAAATATTATTA
TTTAGCAGGAGGTATTATGT

Downstream 100 bases:

>100_bases
TCAATCGTTCATGCAAATACCTTGATTAATAATTTGACTGAAATTCTCTTTGATGTATGAGAACAAAATAAGAGTGTAGG
CTATCCAATAAATAACCTGC

Product: NADH-dependent butanol dehydrogenase A (BDH I)

Products: NA

Alternate protein names: BDH I [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MYNFTFNIPTKIHFGKDTISSLSELKAYGSKVLLVYGGGSIKKNGLYDTAMKILKDAGLTVFELSGVEPNPKIETVRKGV
EICKNEGIDMVLAIGGGSTIDCSKVVAAGAKYDGDAWDLVLDGSKVKAALPIFDVLTLSATGTEMDPFAVISDMSKNEKW
GTGSPYMVPTMSILNPEYTFSVSKKQTAAGTADMMSHTMENYFSMENADCQKFMAEGLLRTMIKNGPVALAQPDNYEARA
NLMWAGTHAINGVVGDGCSPAWCVHPMEHELSAFYDITHGEGLAILTPAWMEHILNDDTLPMFVEFAKNVWGLSGDDDYA
LAHAGIDALKKFFFETMGIPANLRAVGITDDRNFEVMAKKACEGSKGSFVPLSKDDIVEIYRAAF

Sequences:

>Translated_385_residues
MYNFTFNIPTKIHFGKDTISSLSELKAYGSKVLLVYGGGSIKKNGLYDTAMKILKDAGLTVFELSGVEPNPKIETVRKGV
EICKNEGIDMVLAIGGGSTIDCSKVVAAGAKYDGDAWDLVLDGSKVKAALPIFDVLTLSATGTEMDPFAVISDMSKNEKW
GTGSPYMVPTMSILNPEYTFSVSKKQTAAGTADMMSHTMENYFSMENADCQKFMAEGLLRTMIKNGPVALAQPDNYEARA
NLMWAGTHAINGVVGDGCSPAWCVHPMEHELSAFYDITHGEGLAILTPAWMEHILNDDTLPMFVEFAKNVWGLSGDDDYA
LAHAGIDALKKFFFETMGIPANLRAVGITDDRNFEVMAKKACEGSKGSFVPLSKDDIVEIYRAAF
>Mature_385_residues
MYNFTFNIPTKIHFGKDTISSLSELKAYGSKVLLVYGGGSIKKNGLYDTAMKILKDAGLTVFELSGVEPNPKIETVRKGV
EICKNEGIDMVLAIGGGSTIDCSKVVAAGAKYDGDAWDLVLDGSKVKAALPIFDVLTLSATGTEMDPFAVISDMSKNEKW
GTGSPYMVPTMSILNPEYTFSVSKKQTAAGTADMMSHTMENYFSMENADCQKFMAEGLLRTMIKNGPVALAQPDNYEARA
NLMWAGTHAINGVVGDGCSPAWCVHPMEHELSAFYDITHGEGLAILTPAWMEHILNDDTLPMFVEFAKNVWGLSGDDDYA
LAHAGIDALKKFFFETMGIPANLRAVGITDDRNFEVMAKKACEGSKGSFVPLSKDDIVEIYRAAF

Specific function: Unknown

COG id: COG1979

COG function: function code C; Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789386, Length=368, Percent_Identity=38.5869565217391, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI48994951, Length=386, Percent_Identity=27.2020725388601, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1787493, Length=378, Percent_Identity=25.9259259259259, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789163, Length=387, Percent_Identity=27.6485788113695, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082107, Length=289, Percent_Identity=25.2595155709343, Blast_Score=79, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6321181, Length=384, Percent_Identity=26.8229166666667, Blast_Score=114, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 41779; Mature: 41779

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNFTFNIPTKIHFGKDTISSLSELKAYGSKVLLVYGGGSIKKNGLYDTAMKILKDAGLT
CCEEEEECCCEEEECHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCE
VFELSGVEPNPKIETVRKGVEICKNEGIDMVLAIGGGSTIDCSKVVAAGAKYDGDAWDLV
EEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHCCCCCCCCEEEEE
LDGSKVKAALPIFDVLTLSATGTEMDPFAVISDMSKNEKWGTGSPYMVPTMSILNPEYTF
ECCCCCEECCCCEEEEEEECCCCCCCCHHHHHCCCCCCCCCCCCCEEEEEHHHCCCCEEE
SVSKKQTAAGTADMMSHTMENYFSMENADCQKFMAEGLLRTMIKNGPVALAQPDNYEARA
EECCCHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEE
NLMWAGTHAINGVVGDGCSPAWCVHPMEHELSAFYDITHGEGLAILTPAWMEHILNDDTL
EEEEECCHHHCCCCCCCCCCCEECCCHHHHHHHHEEECCCCCEEEECHHHHHHHHCCCCH
PMFVEFAKNVWGLSGDDDYALAHAGIDALKKFFFETMGIPANLRAVGITDDRNFEVMAKK
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHH
ACEGSKGSFVPLSKDDIVEIYRAAF
HCCCCCCCEECCCHHHHHHHHHHCC
>Mature Secondary Structure
MYNFTFNIPTKIHFGKDTISSLSELKAYGSKVLLVYGGGSIKKNGLYDTAMKILKDAGLT
CCEEEEECCCEEEECHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCE
VFELSGVEPNPKIETVRKGVEICKNEGIDMVLAIGGGSTIDCSKVVAAGAKYDGDAWDLV
EEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHCCCCCCCCEEEEE
LDGSKVKAALPIFDVLTLSATGTEMDPFAVISDMSKNEKWGTGSPYMVPTMSILNPEYTF
ECCCCCEECCCCEEEEEEECCCCCCCCHHHHHCCCCCCCCCCCCCEEEEEHHHCCCCEEE
SVSKKQTAAGTADMMSHTMENYFSMENADCQKFMAEGLLRTMIKNGPVALAQPDNYEARA
EECCCHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEE
NLMWAGTHAINGVVGDGCSPAWCVHPMEHELSAFYDITHGEGLAILTPAWMEHILNDDTL
EEEEECCHHHCCCCCCCCCCCEECCCHHHHHHHHEEECCCCCEEEECHHHHHHHHCCCCH
PMFVEFAKNVWGLSGDDDYALAHAGIDALKKFFFETMGIPANLRAVGITDDRNFEVMAKK
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHH
ACEGSKGSFVPLSKDDIVEIYRAAF
HCCCCCCCEECCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1385386; 11466286; 1809209 [H]