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The map label for this gene is yugH [H]

Identifier: 238925348

GI number: 238925348

Start: 2880972

End: 2882150

Strand: Reverse

Name: yugH [H]

Synonym: EUBREC_3003

Alternate gene names: 238925348

Gene position: 2882150-2880972 (Counterclockwise)

Preceding gene: 238925349

Following gene: 238925347

Centisome position: 83.55

GC content: 47.24

Gene sequence:

>1179_bases
ATGAGAGACCCTTTATCCAGTACCATAAAGACTATCCAGCCATCGGGCATCCGTAAGTTTTTTGATATAGTGAGCGAGAT
GAAGGATGCGATATCGCTCGGAGTAGGTGAGCCTGATTTTGACACACCGTGGCATATCAGGGATGAGGGCATATATTCCC
TTGAAAAGGGACGCACCTTCTACACCTCAAATGCCGGACTCAAGGAGTTAAAGATTGAGATTGCAAAATATCTCGACAGA
AGATACGGCATGACATATGATTACAACAAAGAGATCATGGTAACTGTCGGCGGCAGCGAGGCTATAGATATCGCACTGCG
CGCCATGCTCGATGCGGGAGATGAGGTGATTATCCCGCAGCCAAGCTATGTTTCATATGTGCCATGTACTGTGCTGGCAG
GTGGCACACCTGTGATTGTGGAGCTCAAGGAGGAAAATGATTTCAGGCTGACAGCCGAGGAGCTTGAGGCTGTTATCACT
CCAAAGACAAAGATACTTATCATGCCTTTCCCTAATAACCCTACAGGCGCTATCATGGAAAAAGCAGACCTTGAAGCAAT
TGTTCAGGTGGTTAAGGAGCATGATCTGTTTGTGATAAGTGACGAGATTTATTCGGAGCTTACATATGTGGATAAGCATG
TGTCTATAGCATCGTTTCCGGGAATGAAGGAGCGCACAGTGCTCATAAACGGTTTTTCCAAGGCATATGCCATGACAGGT
TGGAGGCTTGGATATGCATGTGCACCTGAGACCATTTTAAAGCAGATGCTAAAGATTCATCAGTTTGCAATCATGTGTGC
GCCGACCACGAGCCAGTATGCGGCTGTCGAGGCTATGAAAAACGGTGATGAGGATGTTGCACAGATGAGGGAGGAATACA
ACGGCCGCAGACGCTATGTGCTTCACCGCTTTAAGGAGATGGGGCTTAAGTGCTTTGAGCCTTTCGGAGCTTTTTATGCG
TTCCCAAGCATCAAGGAGTTTGGCATGAACTCCGATGAGTTTGCCACAAAGCTTCTAAATAGCAAGAAGATTGCCGTGGT
TCCGGGAACTGCATTCGGAGAGTGCGGTGAGGGCTTTTTACGTATATCATATGCATATTCGCTTGATGATTTAAAGGAGG
CGCTCGGCCGCATTGAGGAGTTTGTCACAGAGCTTCGCGCCGGGATGGATAATAAATAG

Upstream 100 bases:

>100_bases
TGCTTTCGACAAAGACAAACTTTATTCTGAAGAAATACAAGGATCATGGAACTATCATGGCGGCACCTGTCAAATCCGAT
GAAAGGGGAATTATGTCATA

Downstream 100 bases:

>100_bases
TTTAAATTGACAGGAGACAAAATGGCAAAGCTGAACATAGTGTTACATGAGCCGGAAATTCCGGCAAATACGGGAAATAT
CGGAAGAACCTGCGTCGCGA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MRDPLSSTIKTIQPSGIRKFFDIVSEMKDAISLGVGEPDFDTPWHIRDEGIYSLEKGRTFYTSNAGLKELKIEIAKYLDR
RYGMTYDYNKEIMVTVGGSEAIDIALRAMLDAGDEVIIPQPSYVSYVPCTVLAGGTPVIVELKEENDFRLTAEELEAVIT
PKTKILIMPFPNNPTGAIMEKADLEAIVQVVKEHDLFVISDEIYSELTYVDKHVSIASFPGMKERTVLINGFSKAYAMTG
WRLGYACAPETILKQMLKIHQFAIMCAPTTSQYAAVEAMKNGDEDVAQMREEYNGRRRYVLHRFKEMGLKCFEPFGAFYA
FPSIKEFGMNSDEFATKLLNSKKIAVVPGTAFGECGEGFLRISYAYSLDDLKEALGRIEEFVTELRAGMDNK

Sequences:

>Translated_392_residues
MRDPLSSTIKTIQPSGIRKFFDIVSEMKDAISLGVGEPDFDTPWHIRDEGIYSLEKGRTFYTSNAGLKELKIEIAKYLDR
RYGMTYDYNKEIMVTVGGSEAIDIALRAMLDAGDEVIIPQPSYVSYVPCTVLAGGTPVIVELKEENDFRLTAEELEAVIT
PKTKILIMPFPNNPTGAIMEKADLEAIVQVVKEHDLFVISDEIYSELTYVDKHVSIASFPGMKERTVLINGFSKAYAMTG
WRLGYACAPETILKQMLKIHQFAIMCAPTTSQYAAVEAMKNGDEDVAQMREEYNGRRRYVLHRFKEMGLKCFEPFGAFYA
FPSIKEFGMNSDEFATKLLNSKKIAVVPGTAFGECGEGFLRISYAYSLDDLKEALGRIEEFVTELRAGMDNK
>Mature_392_residues
MRDPLSSTIKTIQPSGIRKFFDIVSEMKDAISLGVGEPDFDTPWHIRDEGIYSLEKGRTFYTSNAGLKELKIEIAKYLDR
RYGMTYDYNKEIMVTVGGSEAIDIALRAMLDAGDEVIIPQPSYVSYVPCTVLAGGTPVIVELKEENDFRLTAEELEAVIT
PKTKILIMPFPNNPTGAIMEKADLEAIVQVVKEHDLFVISDEIYSELTYVDKHVSIASFPGMKERTVLINGFSKAYAMTG
WRLGYACAPETILKQMLKIHQFAIMCAPTTSQYAAVEAMKNGDEDVAQMREEYNGRRRYVLHRFKEMGLKCFEPFGAFYA
FPSIKEFGMNSDEFATKLLNSKKIAVVPGTAFGECGEGFLRISYAYSLDDLKEALGRIEEFVTELRAGMDNK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=333, Percent_Identity=31.2312312312312, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI169881279, Length=333, Percent_Identity=31.2312312312312, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI56713254, Length=354, Percent_Identity=29.9435028248588, Blast_Score=168, Evalue=8e-42,
Organism=Homo sapiens, GI56713256, Length=354, Percent_Identity=29.9435028248588, Blast_Score=168, Evalue=8e-42,
Organism=Homo sapiens, GI169881281, Length=230, Percent_Identity=31.7391304347826, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI4507369, Length=384, Percent_Identity=23.6979166666667, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI215599424, Length=378, Percent_Identity=26.1904761904762, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI19263340, Length=378, Percent_Identity=26.1904761904762, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI4885351, Length=367, Percent_Identity=25.6130790190736, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI187936925, Length=392, Percent_Identity=23.2142857142857, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI14211921, Length=392, Percent_Identity=23.2142857142857, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1786816, Length=364, Percent_Identity=29.3956043956044, Blast_Score=195, Evalue=3e-51,
Organism=Escherichia coli, GI1788722, Length=374, Percent_Identity=31.5508021390374, Blast_Score=181, Evalue=5e-47,
Organism=Escherichia coli, GI1788627, Length=376, Percent_Identity=29.7872340425532, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1790797, Length=385, Percent_Identity=25.4545454545455, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787710, Length=328, Percent_Identity=23.4756097560976, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788332, Length=230, Percent_Identity=23.4782608695652, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71994472, Length=403, Percent_Identity=30.7692307692308, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI71994476, Length=403, Percent_Identity=30.7692307692308, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17567369, Length=356, Percent_Identity=28.3707865168539, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17567663, Length=303, Percent_Identity=25.0825082508251, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71981209, Length=373, Percent_Identity=25.4691689008043, Blast_Score=89, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6322401, Length=332, Percent_Identity=27.710843373494, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6320317, Length=339, Percent_Identity=27.4336283185841, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6323118, Length=375, Percent_Identity=25.8666666666667, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28573069, Length=406, Percent_Identity=24.384236453202, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24646114, Length=406, Percent_Identity=24.384236453202, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI28573067, Length=406, Percent_Identity=24.384236453202, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI28573065, Length=406, Percent_Identity=24.384236453202, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI18859735, Length=379, Percent_Identity=25.8575197889182, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24641770, Length=398, Percent_Identity=27.6381909547739, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24641760, Length=398, Percent_Identity=27.6381909547739, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24641768, Length=398, Percent_Identity=27.6381909547739, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24641766, Length=398, Percent_Identity=27.6381909547739, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24641764, Length=398, Percent_Identity=27.6381909547739, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI45551451, Length=398, Percent_Identity=27.6381909547739, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21356535, Length=333, Percent_Identity=23.4234234234234, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 44018; Mature: 44018

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDPLSSTIKTIQPSGIRKFFDIVSEMKDAISLGVGEPDFDTPWHIRDEGIYSLEKGRTF
CCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCEEECCCCEE
YTSNAGLKELKIEIAKYLDRRYGMTYDYNKEIMVTVGGSEAIDIALRAMLDAGDEVIIPQ
EECCCCHHHHHHHHHHHHHHHCCCCEECCCEEEEEECCCHHHHHHHHHHHCCCCEEEECC
PSYVSYVPCTVLAGGTPVIVELKEENDFRLTAEELEAVITPKTKILIMPFPNNPTGAIME
CCCCCCCCEEEECCCCEEEEEEECCCCCEEEHHHHHHHCCCCEEEEEEECCCCCCCHHHH
KADLEAIVQVVKEHDLFVISDEIYSELTYVDKHVSIASFPGMKERTVLINGFSKAYAMTG
HHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHCCEEECCCCCCCCEEEEECCHHHHHHCC
WRLGYACAPETILKQMLKIHQFAIMCAPTTSQYAAVEAMKNGDEDVAQMREEYNGRRRYV
CCCCCCCCHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHH
LHRFKEMGLKCFEPFGAFYAFPSIKEFGMNSDEFATKLLNSKKIAVVPGTAFGECGEGFL
HHHHHHCCHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCEE
RISYAYSLDDLKEALGRIEEFVTELRAGMDNK
EEEEEECHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRDPLSSTIKTIQPSGIRKFFDIVSEMKDAISLGVGEPDFDTPWHIRDEGIYSLEKGRTF
CCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCEEECCCCEE
YTSNAGLKELKIEIAKYLDRRYGMTYDYNKEIMVTVGGSEAIDIALRAMLDAGDEVIIPQ
EECCCCHHHHHHHHHHHHHHHCCCCEECCCEEEEEECCCHHHHHHHHHHHCCCCEEEECC
PSYVSYVPCTVLAGGTPVIVELKEENDFRLTAEELEAVITPKTKILIMPFPNNPTGAIME
CCCCCCCCEEEECCCCEEEEEEECCCCCEEEHHHHHHHCCCCEEEEEEECCCCCCCHHHH
KADLEAIVQVVKEHDLFVISDEIYSELTYVDKHVSIASFPGMKERTVLINGFSKAYAMTG
HHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHCCEEECCCCCCCCEEEEECCHHHHHHCC
WRLGYACAPETILKQMLKIHQFAIMCAPTTSQYAAVEAMKNGDEDVAQMREEYNGRRRYV
CCCCCCCCHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHH
LHRFKEMGLKCFEPFGAFYAFPSIKEFGMNSDEFATKLLNSKKIAVVPGTAFGECGEGFL
HHHHHHCCHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCEE
RISYAYSLDDLKEALGRIEEFVTELRAGMDNK
EEEEEECHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]