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The map label for this gene is yycF [H]

Identifier: 238925292

GI number: 238925292

Start: 2829331

End: 2830011

Strand: Reverse

Name: yycF [H]

Synonym: EUBREC_2946

Alternate gene names: 238925292

Gene position: 2830011-2829331 (Counterclockwise)

Preceding gene: 238925293

Following gene: 238925291

Centisome position: 82.04

GC content: 44.49

Gene sequence:

>681_bases
ATGGAGAAAGCTATGGCACTTATTTATATTGTAGAGGACGACGAGAGCATACGTGAGATAGAGAGTATTGCTTTAAAAAA
CAGTAATTACATAGTCAGTGCATTTGAAAATGCAAAGGAATTTTACAAGAAGCTGGATGAACTCGTACCGGACCTTATAC
TGCTTGATGTGATGCTTCCGGATGAGAGCGGCTACGATATCGTGAGAAAGCTCAGAAAACGTCCGGCCACACAGGATATT
CCTATTATAATGGTCACAGCCAAGACAACAGAGATGGATATGATAAAAGGGTTTGACGGAGGCGCAGATGATTACATCAA
AAAGCCTTTCTCAATCATGGAGCTTATCACAAGAGTAAAGGCACTGCTCAGGAGAACAGCGAAGGAGGAGCCGAAGCTTT
TAAAGCTGGATGATCTGGTGATTGACCATGAGCGCCATGTGGTTACAGTGAACAATGAGCCGGTTGACCTTACATACAAG
GAGTACGAGCTTTTAAGGCTTCTGATGGGCAGTCAGGGAATAGTCATGACCAGGGAGGTCATCATGAGAAGCGTCTGGGA
TACTGACTTTGAGGGCGAGACACGTACAGTGGACATGCACATAAAGACACTCCGCCATAAGCTGGGTGACTATGGCAGCA
GGATAAAGACAGTCAGAAATGTGGGCTATGTTATAGAATAA

Upstream 100 bases:

>100_bases
ATTTTACATAAATTTTACATAAAACCATCGTCTGTTTTACATTAGTAATGTATAATCGAAAGTAAAAAGCAGGTAAAAAT
TTTACATAAGATTTTTTGAA

Downstream 100 bases:

>100_bases
TAGCTGTTATAATGATTTCTAATATACATAAGCGGAGCGTACAGCATGAAAAAGAAGATTAATTACTATCTGGTAGCAAC
AGCACTTTTTGTAGCAATTG

Product: DNA-binding response regulator, OmpR family (Rec-wHTH domains)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MEKAMALIYIVEDDESIREIESIALKNSNYIVSAFENAKEFYKKLDELVPDLILLDVMLPDESGYDIVRKLRKRPATQDI
PIIMVTAKTTEMDMIKGFDGGADDYIKKPFSIMELITRVKALLRRTAKEEPKLLKLDDLVIDHERHVVTVNNEPVDLTYK
EYELLRLLMGSQGIVMTREVIMRSVWDTDFEGETRTVDMHIKTLRHKLGDYGSRIKTVRNVGYVIE

Sequences:

>Translated_226_residues
MEKAMALIYIVEDDESIREIESIALKNSNYIVSAFENAKEFYKKLDELVPDLILLDVMLPDESGYDIVRKLRKRPATQDI
PIIMVTAKTTEMDMIKGFDGGADDYIKKPFSIMELITRVKALLRRTAKEEPKLLKLDDLVIDHERHVVTVNNEPVDLTYK
EYELLRLLMGSQGIVMTREVIMRSVWDTDFEGETRTVDMHIKTLRHKLGDYGSRIKTVRNVGYVIE
>Mature_226_residues
MEKAMALIYIVEDDESIREIESIALKNSNYIVSAFENAKEFYKKLDELVPDLILLDVMLPDESGYDIVRKLRKRPATQDI
PIIMVTAKTTEMDMIKGFDGGADDYIKKPFSIMELITRVKALLRRTAKEEPKLLKLDDLVIDHERHVVTVNNEPVDLTYK
EYELLRLLMGSQGIVMTREVIMRSVWDTDFEGETRTVDMHIKTLRHKLGDYGSRIKTVRNVGYVIE

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=221, Percent_Identity=38.9140271493213, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=38.5650224215247, Blast_Score=140, Evalue=7e-35,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=35.7142857142857, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=35.7798165137615, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI87082012, Length=219, Percent_Identity=35.1598173515982, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=38.0530973451327, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=32.4200913242009, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=30.7692307692308, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=32.8947368421053, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=33.4821428571429, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787229, Length=209, Percent_Identity=33.9712918660287, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI2367329, Length=180, Percent_Identity=35.5555555555556, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI145693140, Length=237, Percent_Identity=32.0675105485232, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=26.7543859649123, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1790299, Length=138, Percent_Identity=27.536231884058, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26156; Mature: 26156

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKAMALIYIVEDDESIREIESIALKNSNYIVSAFENAKEFYKKLDELVPDLILLDVMLP
CCCCEEEEEEEECCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHEEHEEECC
DESGYDIVRKLRKRPATQDIPIIMVTAKTTEMDMIKGFDGGADDYIKKPFSIMELITRVK
CCCCHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHCCCCCHHHHHHCCHHHHHHHHHHH
ALLRRTAKEEPKLLKLDDLVIDHERHVVTVNNEPVDLTYKEYELLRLLMGSQGIVMTREV
HHHHHHHHCCCCEEEEHHEEEECCCEEEEECCCCCEEEHHHHHHHHHHHCCCCCHHHHHH
IMRSVWDTDFEGETRTVDMHIKTLRHKLGDYGSRIKTVRNVGYVIE
HHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEKAMALIYIVEDDESIREIESIALKNSNYIVSAFENAKEFYKKLDELVPDLILLDVMLP
CCCCEEEEEEEECCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHEEHEEECC
DESGYDIVRKLRKRPATQDIPIIMVTAKTTEMDMIKGFDGGADDYIKKPFSIMELITRVK
CCCCHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHCCCCCHHHHHHCCHHHHHHHHHHH
ALLRRTAKEEPKLLKLDDLVIDHERHVVTVNNEPVDLTYKEYELLRLLMGSQGIVMTREV
HHHHHHHHCCCCEEEEHHEEEECCCEEEEECCCCCEEEHHHHHHHHHHHCCCCCHHHHHH
IMRSVWDTDFEGETRTVDMHIKTLRHKLGDYGSRIKTVRNVGYVIE
HHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]