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The map label for this gene is htrA [H]

Identifier: 238925260

GI number: 238925260

Start: 2792237

End: 2793505

Strand: Reverse

Name: htrA [H]

Synonym: EUBREC_2914

Alternate gene names: 238925260

Gene position: 2793505-2792237 (Counterclockwise)

Preceding gene: 238925265

Following gene: 238925259

Centisome position: 80.98

GC content: 45.39

Gene sequence:

>1269_bases
ATGGAGCAATTTATCAGAGAAAAGATAAAGGATAAACCGCTGAATAAAAAAAGACTTGCAAAAAAAGCTGGCACAGCAGC
ACTCTGCGGAGTGGCATTTGCAGTGGCTGCAAGCATTGTTTTTGCTATATTTCTGCCGGTTATCAACAGACAATCAAAAA
AAGCTTCAGATGGAAAAAATAATAATGATGTGCAGACAGCCACACAGCAGCCGGGCATAGATGACAGCAGTGATGCATAT
AGTGAAAATGGTACACAAAGCACAGAGTCCGGCACTTCTTCGGAGTCGTCTTCGCAGACCTATCAGCCTACACTCGCAGA
TTATCAGGCAGTGCAGAACCAGCTCTACAGAGTGGGCACTTCGGCCACGAAATTTGTAGTAGGAGTCACGGGTGTGACAG
ATGCCACTGATATTTTCAATAATTCCTATGAGACCGAGGGTCAGGGAGTGGGAGTGATACTGAGGGACAATGGAAAGCAG
CTAATCATTCTGACAGAGAAAAATGTAGTGGATAAGGCGGATAAGCTTAGTGTAACCTTTGTAAACGACATGATGGCTGA
TGCTGCGCTGGTCAAGTATGACAGCAATACAGGTATAGCAATCATTTCCGTGGATAAGTCGCTTCTGGACGACGCCACAA
TAAGGGCTATAGCGGTTGCGGAGCTTGGTAATTCAAATATTGTTTCAAGAGGAGCATCTGTCATTGCACTTGAGGCAAAC
TATGCCATTCTCACAGGTCTTGTAACGTCAACAACCAACGAGCTGTCGGCGCAGGACAACAATTACTCGGTGCTCACCAC
AGATATCGCAAGCAACAAGTTACAGAGCGGTATACTGATTAATACAGATGGTCAGGTCATAGGGCTTTCGCTGCAGGATT
TCAATCCGGCGGAGGAAAACAATACGCTCACGGCTGTCAGCATAAGCGACCTGTCACCTGTCATTGAAAAGATCGAGAGC
GGCGCGGATGTGCCGTACATAGGCATCACCTGTACTACAGTTACAGAAAAAATAGCAAACAGATATAACATCCCAAAGGG
TGTTTATATAAAGCAGGTTACCATGGATTCACCGGCATTTGTTTCTGGGCTTCAAAGCGGAGATGTGATAGTTGCGGTAA
ACAATACAGAGGTGTCGAATGTGTCCGCGTACAACACACAGCTTATGAAGCAAAAGCCTGAGGATACCTGCAATCTGAAA
GTAAAGAGAAAAGGAAGCAACGGCTACACGGAGATTACCTGTCAGGTGAAAATCGGAGTGATGAATTAG

Upstream 100 bases:

>100_bases
AGCGTACTCAAAGGCGTACTCAAAAAATATGGTTGCAACGCAATATAATTCAGAATATAATGTAAGATAGTAACTAAAGA
CATCTAATCAGGGTGACAAT

Downstream 100 bases:

>100_bases
CCGAAATTAGGAGGATATATGAAGTATATTTCAACTCTCCGCGAGGGAGAGAGAATCAATGAGATTTTTTTATGCAAGAG
CAAGCAGACAGCCATGACCA

Product: HtrA-like serine protease (with PDZ domain)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MEQFIREKIKDKPLNKKRLAKKAGTAALCGVAFAVAASIVFAIFLPVINRQSKKASDGKNNNDVQTATQQPGIDDSSDAY
SENGTQSTESGTSSESSSQTYQPTLADYQAVQNQLYRVGTSATKFVVGVTGVTDATDIFNNSYETEGQGVGVILRDNGKQ
LIILTEKNVVDKADKLSVTFVNDMMADAALVKYDSNTGIAIISVDKSLLDDATIRAIAVAELGNSNIVSRGASVIALEAN
YAILTGLVTSTTNELSAQDNNYSVLTTDIASNKLQSGILINTDGQVIGLSLQDFNPAEENNTLTAVSISDLSPVIEKIES
GADVPYIGITCTTVTEKIANRYNIPKGVYIKQVTMDSPAFVSGLQSGDVIVAVNNTEVSNVSAYNTQLMKQKPEDTCNLK
VKRKGSNGYTEITCQVKIGVMN

Sequences:

>Translated_422_residues
MEQFIREKIKDKPLNKKRLAKKAGTAALCGVAFAVAASIVFAIFLPVINRQSKKASDGKNNNDVQTATQQPGIDDSSDAY
SENGTQSTESGTSSESSSQTYQPTLADYQAVQNQLYRVGTSATKFVVGVTGVTDATDIFNNSYETEGQGVGVILRDNGKQ
LIILTEKNVVDKADKLSVTFVNDMMADAALVKYDSNTGIAIISVDKSLLDDATIRAIAVAELGNSNIVSRGASVIALEAN
YAILTGLVTSTTNELSAQDNNYSVLTTDIASNKLQSGILINTDGQVIGLSLQDFNPAEENNTLTAVSISDLSPVIEKIES
GADVPYIGITCTTVTEKIANRYNIPKGVYIKQVTMDSPAFVSGLQSGDVIVAVNNTEVSNVSAYNTQLMKQKPEDTCNLK
VKRKGSNGYTEITCQVKIGVMN
>Mature_422_residues
MEQFIREKIKDKPLNKKRLAKKAGTAALCGVAFAVAASIVFAIFLPVINRQSKKASDGKNNNDVQTATQQPGIDDSSDAY
SENGTQSTESGTSSESSSQTYQPTLADYQAVQNQLYRVGTSATKFVVGVTGVTDATDIFNNSYETEGQGVGVILRDNGKQ
LIILTEKNVVDKADKLSVTFVNDMMADAALVKYDSNTGIAIISVDKSLLDDATIRAIAVAELGNSNIVSRGASVIALEAN
YAILTGLVTSTTNELSAQDNNYSVLTTDIASNKLQSGILINTDGQVIGLSLQDFNPAEENNTLTAVSISDLSPVIEKIES
GADVPYIGITCTTVTEKIANRYNIPKGVYIKQVTMDSPAFVSGLQSGDVIVAVNNTEVSNVSAYNTQLMKQKPEDTCNLK
VKRKGSNGYTEITCQVKIGVMN

Specific function: May be involved in processing, maturation, or secretion of extracellular enzymes [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 44991; Mature: 44991

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQFIREKIKDKPLNKKRLAKKAGTAALCGVAFAVAASIVFAIFLPVINRQSKKASDGKN
CCHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
NNDVQTATQQPGIDDSSDAYSENGTQSTESGTSSESSSQTYQPTLADYQAVQNQLYRVGT
CCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
SATKFVVGVTGVTDATDIFNNSYETEGQGVGVILRDNGKQLIILTEKNVVDKADKLSVTF
CCEEEEEEECCCCCHHHHHCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCEEEEE
VNDMMADAALVKYDSNTGIAIISVDKSLLDDATIRAIAVAELGNSNIVSRGASVIALEAN
HHHHHHCEEEEEECCCCCEEEEEECHHHHCCHHEEEEEEEECCCCCHHHCCCEEEEEECC
YAILTGLVTSTTNELSAQDNNYSVLTTDIASNKLQSGILINTDGQVIGLSLQDFNPAEEN
CEEEEEEHHCCCCHHCCCCCCEEEEEECCCCCHHCCCEEEECCCCEEEEEECCCCCCCCC
NTLTAVSISDLSPVIEKIESGADVPYIGITCTTVTEKIANRYNIPKGVYIKQVTMDSPAF
CEEEEEEEHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHCCCCCCEEEEEEECCCCHH
VSGLQSGDVIVAVNNTEVSNVSAYNTQLMKQKPEDTCNLKVKRKGSNGYTEITCQVKIGV
HHCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEEEEEEEE
MN
CC
>Mature Secondary Structure
MEQFIREKIKDKPLNKKRLAKKAGTAALCGVAFAVAASIVFAIFLPVINRQSKKASDGKN
CCHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
NNDVQTATQQPGIDDSSDAYSENGTQSTESGTSSESSSQTYQPTLADYQAVQNQLYRVGT
CCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
SATKFVVGVTGVTDATDIFNNSYETEGQGVGVILRDNGKQLIILTEKNVVDKADKLSVTF
CCEEEEEEECCCCCHHHHHCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCEEEEE
VNDMMADAALVKYDSNTGIAIISVDKSLLDDATIRAIAVAELGNSNIVSRGASVIALEAN
HHHHHHCEEEEEECCCCCEEEEEECHHHHCCHHEEEEEEEECCCCCHHHCCCEEEEEECC
YAILTGLVTSTTNELSAQDNNYSVLTTDIASNKLQSGILINTDGQVIGLSLQDFNPAEEN
CEEEEEEHHCCCCHHCCCCCCEEEEEECCCCCHHCCCEEEECCCCEEEEEECCCCCCCCC
NTLTAVSISDLSPVIEKIESGADVPYIGITCTTVTEKIANRYNIPKGVYIKQVTMDSPAF
CEEEEEEEHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHCCCCCCEEEEEEECCCCHH
VSGLQSGDVIVAVNNTEVSNVSAYNTQLMKQKPEDTCNLKVKRKGSNGYTEITCQVKIGV
HHCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEEEEEEEE
MN
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 10692364; 11133960; 11555295 [H]