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The map label for this gene is cisA [H]

Identifier: 238925057

GI number: 238925057

Start: 2577962

End: 2579632

Strand: Direct

Name: cisA [H]

Synonym: EUBREC_2709

Alternate gene names: 238925057

Gene position: 2577962-2579632 (Clockwise)

Preceding gene: 238925056

Following gene: 238925058

Centisome position: 74.73

GC content: 50.57

Gene sequence:

>1671_bases
ATGGCTATGATGAACGAAATGGAATACAGAACAATCGGTTCGGCACTTGCCGGGGGCTATCGTGCAGCGGTCTATTGCAG
ACTGTCAAAGGACGATGACCTGCAAGGCGAAAGTGCCAGTATCGCAAACCAGCGTGATATGCTGGAAAAATACTGCGAAA
AGCAGGGATGGGAGGTTGTGGCAGTCTATCAGGACGATGGCTTCACAGGTCTTAATATGGAGCGTCCTGATTTACAGAGA
ATGTTGAGAGCCATTGAGCGCAGGCAAATCAACCTTGTCATCACGAAAGACCTCAGCCGACTGGGGCGGAACTATCTGCA
AACCGGGCATTTGATTGAGGACTTTTTCCCAAGAAACGGTGTCCGCTATATCGCCATGAATGACGGTATCGACACCCTGC
GGGATAACAACGATATTGCCCCGTTCAAGAATATCCTGAACGAGATGTACAGCAAGGATATTTCCAAGAAAGTCCATTCC
TCTTATCTTCTGAAAGCGCAGAAAGGACAGTTTACCGGGTGTCTTGCCCCGTTTGGGTATCGGAAAGACCCGGAGGACAA
AAACCATCTGCTCATTGACGAGGAAACCGCCCCGATTGTGCGACTGATTTTCGGATATGCCCTGAACGGTCATGGTCCGA
ACTATATCCGCAGACGGCTGGAGGAAGAAAAAATCCCCTGCCCCACATGGTGGAACCGGGAACGGGGGCTTCGCAATACC
CGCACCAAATGGGAAAAGAAAGACCCAGAAAAAGGACGGTATATGTGGGACTTCTCCGTTATCAAAGACCTTTTGATGAA
TCCCGTCTACACCGGGGCGATTGCTTCCCAGAAAAAAGACTACCGTTTCAAAATCGGCACGATTGGGGAAAAGAAGCCGG
AGGACTGGATTGTGGTGGAGGGACAGCATGAACCGCTGATTGACCGCATGAGCTTTGACATTGTGCAGAACAAGCTGAAA
TCTCGCCAGCGTCCGGGGCAGACCAATGAAATCAGCCTGTTTGCCGGACTGATAAAATGCGGCGAGTGTGGGAAGTCGCT
GACGATACGCTACACAAACGCAAAACATCCCCAGCAAATTTATTCCTGCAAGACCTACAATGCCTTTGGAAAGAACCACT
GCACCCAGCACCGGATTGACTATGACACCCTTTGCAGCCATGTGCTGCGGAAAATCAGGGAATGTGCCAGAGCTGCCCTG
ATGGACGGGGAAGCGGTTGCCGACCGCCTGACCAATACCTGTGAAGCAGAGCAGCGGGAACAGCGGGAAGCAATGGAACG
CTCCCTCACAAGGGACGAGGAACGGATTGAGGTTCTGGACAAAATGGTCATGCGGCTTTATGAGGATATGATTGCAGGGC
GTATCAGTGAGCAGAATTTCAACACCATGCTGGAAAAGACACAGACCGAGCAGACGGAGCTTAAAGCAAAGGTGTCCGAG
GGCAGAAAGCGGCTGTCTGATGAAGTCCAGCTTGCCAATGACGCAAAACAATGGGTGGAAGCCATTCAGGAATATGCCAA
CATCACAGAGCTGGACGCAGCCACCCTTAACCGCTTAATCAAAGAAATCGTCGTGCATGAGCGCATTGACGAAGATAAAA
CAAGACACATTTCTATCGAAATTCATTTTAATCTCAAACCCATCCCGGAGGTGGAACAGGTCAGTGCCTGA

Upstream 100 bases:

>100_bases
AAAGACAAATTCAAAAGAATATCTTGCTAAAAAGAAAGATTTGAAGTATAATGAAGATGAGGTTCAAAAGAGCCAGATAC
CGTCTGGATTGTGTGGGTAA

Downstream 100 bases:

>100_bases
CCTGTCCCGCCGGGACGGTTCTCTTAAAAACACCATATAGATTTTTTGTACGCCGCCGCTCGCCATCGAGCAGAGTTTTA
CACCTAATTGGGGATAAAAC

Product: cassette chromosome recombinase B

Products: NA

Alternate protein names: Stage IV sporulation protein CA [H]

Number of amino acids: Translated: 556; Mature: 555

Protein sequence:

>556_residues
MAMMNEMEYRTIGSALAGGYRAAVYCRLSKDDDLQGESASIANQRDMLEKYCEKQGWEVVAVYQDDGFTGLNMERPDLQR
MLRAIERRQINLVITKDLSRLGRNYLQTGHLIEDFFPRNGVRYIAMNDGIDTLRDNNDIAPFKNILNEMYSKDISKKVHS
SYLLKAQKGQFTGCLAPFGYRKDPEDKNHLLIDEETAPIVRLIFGYALNGHGPNYIRRRLEEEKIPCPTWWNRERGLRNT
RTKWEKKDPEKGRYMWDFSVIKDLLMNPVYTGAIASQKKDYRFKIGTIGEKKPEDWIVVEGQHEPLIDRMSFDIVQNKLK
SRQRPGQTNEISLFAGLIKCGECGKSLTIRYTNAKHPQQIYSCKTYNAFGKNHCTQHRIDYDTLCSHVLRKIRECARAAL
MDGEAVADRLTNTCEAEQREQREAMERSLTRDEERIEVLDKMVMRLYEDMIAGRISEQNFNTMLEKTQTEQTELKAKVSE
GRKRLSDEVQLANDAKQWVEAIQEYANITELDAATLNRLIKEIVVHERIDEDKTRHISIEIHFNLKPIPEVEQVSA

Sequences:

>Translated_556_residues
MAMMNEMEYRTIGSALAGGYRAAVYCRLSKDDDLQGESASIANQRDMLEKYCEKQGWEVVAVYQDDGFTGLNMERPDLQR
MLRAIERRQINLVITKDLSRLGRNYLQTGHLIEDFFPRNGVRYIAMNDGIDTLRDNNDIAPFKNILNEMYSKDISKKVHS
SYLLKAQKGQFTGCLAPFGYRKDPEDKNHLLIDEETAPIVRLIFGYALNGHGPNYIRRRLEEEKIPCPTWWNRERGLRNT
RTKWEKKDPEKGRYMWDFSVIKDLLMNPVYTGAIASQKKDYRFKIGTIGEKKPEDWIVVEGQHEPLIDRMSFDIVQNKLK
SRQRPGQTNEISLFAGLIKCGECGKSLTIRYTNAKHPQQIYSCKTYNAFGKNHCTQHRIDYDTLCSHVLRKIRECARAAL
MDGEAVADRLTNTCEAEQREQREAMERSLTRDEERIEVLDKMVMRLYEDMIAGRISEQNFNTMLEKTQTEQTELKAKVSE
GRKRLSDEVQLANDAKQWVEAIQEYANITELDAATLNRLIKEIVVHERIDEDKTRHISIEIHFNLKPIPEVEQVSA
>Mature_555_residues
AMMNEMEYRTIGSALAGGYRAAVYCRLSKDDDLQGESASIANQRDMLEKYCEKQGWEVVAVYQDDGFTGLNMERPDLQRM
LRAIERRQINLVITKDLSRLGRNYLQTGHLIEDFFPRNGVRYIAMNDGIDTLRDNNDIAPFKNILNEMYSKDISKKVHSS
YLLKAQKGQFTGCLAPFGYRKDPEDKNHLLIDEETAPIVRLIFGYALNGHGPNYIRRRLEEEKIPCPTWWNRERGLRNTR
TKWEKKDPEKGRYMWDFSVIKDLLMNPVYTGAIASQKKDYRFKIGTIGEKKPEDWIVVEGQHEPLIDRMSFDIVQNKLKS
RQRPGQTNEISLFAGLIKCGECGKSLTIRYTNAKHPQQIYSCKTYNAFGKNHCTQHRIDYDTLCSHVLRKIRECARAALM
DGEAVADRLTNTCEAEQREQREAMERSLTRDEERIEVLDKMVMRLYEDMIAGRISEQNFNTMLEKTQTEQTELKAKVSEG
RKRLSDEVQLANDAKQWVEAIQEYANITELDAATLNRLIKEIVVHERIDEDKTRHISIEIHFNLKPIPEVEQVSA

Specific function: Putative site-specific recombinase having a very important role in sporulation. It probably plays a role in the recombination of spoIIIC and spoIVCB to form sigma K factor [H]

COG id: COG1961

COG function: function code L; Site-specific recombinases, DNA invertase Pin homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 recombinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011109
- InterPro:   IPR006118
- InterPro:   IPR006119 [H]

Pfam domain/function: PF07508 Recombinase; PF00239 Resolvase [H]

EC number: NA

Molecular weight: Translated: 64554; Mature: 64423

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMMNEMEYRTIGSALAGGYRAAVYCRLSKDDDLQGESASIANQRDMLEKYCEKQGWEVV
CCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEE
AVYQDDGFTGLNMERPDLQRMLRAIERRQINLVITKDLSRLGRNYLQTGHLIEDFFPRNG
EEEECCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHCCHHHHHCCCCC
VRYIAMNDGIDTLRDNNDIAPFKNILNEMYSKDISKKVHSSYLLKAQKGQFTGCLAPFGY
EEEEEECCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCC
RKDPEDKNHLLIDEETAPIVRLIFGYALNGHGPNYIRRRLEEEKIPCPTWWNRERGLRNT
CCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHCCCCHH
RTKWEKKDPEKGRYMWDFSVIKDLLMNPVYTGAIASQKKDYRFKIGTIGEKKPEDWIVVE
HHHCCCCCCCCCCEEEEHHHHHHHHCCCHHHCHHHCCCCCCEEEECCCCCCCCCCEEEEC
GQHEPLIDRMSFDIVQNKLKSRQRPGQTNEISLFAGLIKCGECGKSLTIRYTNAKHPQQI
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHH
YSCKTYNAFGKNHCTQHRIDYDTLCSHVLRKIRECARAALMDGEAVADRLTNTCEAEQRE
HHCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
QREAMERSLTRDEERIEVLDKMVMRLYEDMIAGRISEQNFNTMLEKTQTEQTELKAKVSE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GRKRLSDEVQLANDAKQWVEAIQEYANITELDAATLNRLIKEIVVHERIDEDKTRHISIE
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
IHFNLKPIPEVEQVSA
EEECCCCCCCHHHCCC
>Mature Secondary Structure 
AMMNEMEYRTIGSALAGGYRAAVYCRLSKDDDLQGESASIANQRDMLEKYCEKQGWEVV
CCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEE
AVYQDDGFTGLNMERPDLQRMLRAIERRQINLVITKDLSRLGRNYLQTGHLIEDFFPRNG
EEEECCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHCCHHHHHCCCCC
VRYIAMNDGIDTLRDNNDIAPFKNILNEMYSKDISKKVHSSYLLKAQKGQFTGCLAPFGY
EEEEEECCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCC
RKDPEDKNHLLIDEETAPIVRLIFGYALNGHGPNYIRRRLEEEKIPCPTWWNRERGLRNT
CCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHCCCCHH
RTKWEKKDPEKGRYMWDFSVIKDLLMNPVYTGAIASQKKDYRFKIGTIGEKKPEDWIVVE
HHHCCCCCCCCCCEEEEHHHHHHHHCCCHHHCHHHCCCCCCEEEECCCCCCCCCCEEEEC
GQHEPLIDRMSFDIVQNKLKSRQRPGQTNEISLFAGLIKCGECGKSLTIRYTNAKHPQQI
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHH
YSCKTYNAFGKNHCTQHRIDYDTLCSHVLRKIRECARAALMDGEAVADRLTNTCEAEQRE
HHCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
QREAMERSLTRDEERIEVLDKMVMRLYEDMIAGRISEQNFNTMLEKTQTEQTELKAKVSE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GRKRLSDEVQLANDAKQWVEAIQEYANITELDAATLNRLIKEIVVHERIDEDKTRHISIE
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
IHFNLKPIPEVEQVSA
EEECCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2105293; 7704261; 8969508; 9384377 [H]