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The map label for this gene is ybdL [H]

Identifier: 238922361

GI number: 238922361

Start: 571280

End: 572464

Strand: Reverse

Name: ybdL [H]

Synonym: EUBELI_20597

Alternate gene names: 238922361

Gene position: 572464-571280 (Counterclockwise)

Preceding gene: 238922362

Following gene: 238922360

Centisome position: 91.34

GC content: 40.59

Gene sequence:

>1185_bases
ATGAAAGAGTTAAGTAACAGATCAGCAAATTTTACAGACTCTGTCATCAGAAGAATGACAAGAGTTGCTAATAAATATGG
TGCAGTTAATTTATCACAGGGATTTCCTGATTTTGACCCACCAAAGGCTATAACAGACAGGCTTGCAAGAGTTGCAGGCG
AAGGACCTCATCAGTATGCATTGACATGGGGAGCTAAGAATTTCAGAGATGCAGTTGCTAAGAAATATGAACATTTTTCT
GGTGTTAAGATTGACCCTGAGACAGAGATTGTTGTCACATGCGGAAGTACAGAGGCAATGATGGCTACAATGCTTAGTAT
TATTAATCCGGGTGACAAGGTTGTAATATTCTCGCCTTTTTATGAGAATTACGGTGCAGATACAATTCTTTCAGGCGCAG
AGCCGATATATGTTCCATTAGTTCCACCAGAATTTCATTTTGATAAGGAAAAGTTAGAAGATGCATTCAGACAGGGCGCT
AAGGCATTAATTCTGTGTAATCCTTCCAACCCATGCGGTAAGGTGTTTACAATGGAGGAAATGCAGACAATTGCTGAACT
TGCTAAGAAATATGACGCATATGTTGTTACAGATGAAGTGTATGAGCATATTGTGTATGCACCTAATAAGCATATTTACA
TGCAGTCGCTTGAGGGCATGAGAGAAAGAACGATAGTGTGCAATTCGCTGTCTAAGACATACTCAATAACAGGCTGGAGA
TTAGGTTATGTTATTGCTAACCCACAGATAATCGACAGAGTTAAAAAGGTACATGATTTCCTTACAGTTGGTGCAGCCGC
ACCATTGATGGAGGCAGCAGTTGTGGGATTAGAGTTTGGTGATGGCTATTATGATGAACTTGCCGCACATTATGCACATA
TGAAAGAGGTATTTGTAGGCGGTCTTAAGAAGCTGGGATTAAAATACACAGACCCACAGGGGGCATATTATGTGCTTGTT
GATGTGAGTGAATTCGGAGTTAAAGATGATGTGAAGTTCTGCGAATGGATGGCACAGTTCGTTGGTGTGGCGGCAGTTCC
GGGGTCAAGCTTTTTCAGGGAAGATGTGCATAATCTTGTTAGATTTCATTTTGCAAAGCAGGACGATACACTTAATGAAG
CAATAAAGAGACTGGCAACACTTAAAGAAAAAGCGATTAATGCCAAGAATGTGGACTGGAGATAA

Upstream 100 bases:

>100_bases
AACAGAGAAAGAGTTCTTTTCAGATGAATTAAAAAAATTAATAACAATGTAGTATCAACTACAATTAAAATATCGTATAG
AATAAGGAGGACACATTTAC

Downstream 100 bases:

>100_bases
TTCATGGAAATATACTTAAAACCGATAATTTCAGCGTGTTATGTGTTCCCGGTTCTTGCCGTGCTTTTCACACTGCCATA
TATAATATACGAATATCATA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MKELSNRSANFTDSVIRRMTRVANKYGAVNLSQGFPDFDPPKAITDRLARVAGEGPHQYALTWGAKNFRDAVAKKYEHFS
GVKIDPETEIVVTCGSTEAMMATMLSIINPGDKVVIFSPFYENYGADTILSGAEPIYVPLVPPEFHFDKEKLEDAFRQGA
KALILCNPSNPCGKVFTMEEMQTIAELAKKYDAYVVTDEVYEHIVYAPNKHIYMQSLEGMRERTIVCNSLSKTYSITGWR
LGYVIANPQIIDRVKKVHDFLTVGAAAPLMEAAVVGLEFGDGYYDELAAHYAHMKEVFVGGLKKLGLKYTDPQGAYYVLV
DVSEFGVKDDVKFCEWMAQFVGVAAVPGSSFFREDVHNLVRFHFAKQDDTLNEAIKRLATLKEKAINAKNVDWR

Sequences:

>Translated_394_residues
MKELSNRSANFTDSVIRRMTRVANKYGAVNLSQGFPDFDPPKAITDRLARVAGEGPHQYALTWGAKNFRDAVAKKYEHFS
GVKIDPETEIVVTCGSTEAMMATMLSIINPGDKVVIFSPFYENYGADTILSGAEPIYVPLVPPEFHFDKEKLEDAFRQGA
KALILCNPSNPCGKVFTMEEMQTIAELAKKYDAYVVTDEVYEHIVYAPNKHIYMQSLEGMRERTIVCNSLSKTYSITGWR
LGYVIANPQIIDRVKKVHDFLTVGAAAPLMEAAVVGLEFGDGYYDELAAHYAHMKEVFVGGLKKLGLKYTDPQGAYYVLV
DVSEFGVKDDVKFCEWMAQFVGVAAVPGSSFFREDVHNLVRFHFAKQDDTLNEAIKRLATLKEKAINAKNVDWR
>Mature_394_residues
MKELSNRSANFTDSVIRRMTRVANKYGAVNLSQGFPDFDPPKAITDRLARVAGEGPHQYALTWGAKNFRDAVAKKYEHFS
GVKIDPETEIVVTCGSTEAMMATMLSIINPGDKVVIFSPFYENYGADTILSGAEPIYVPLVPPEFHFDKEKLEDAFRQGA
KALILCNPSNPCGKVFTMEEMQTIAELAKKYDAYVVTDEVYEHIVYAPNKHIYMQSLEGMRERTIVCNSLSKTYSITGWR
LGYVIANPQIIDRVKKVHDFLTVGAAAPLMEAAVVGLEFGDGYYDELAAHYAHMKEVFVGGLKKLGLKYTDPQGAYYVLV
DVSEFGVKDDVKFCEWMAQFVGVAAVPGSSFFREDVHNLVRFHFAKQDDTLNEAIKRLATLKEKAINAKNVDWR

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=401, Percent_Identity=32.6683291770574, Blast_Score=228, Evalue=9e-60,
Organism=Homo sapiens, GI56713256, Length=401, Percent_Identity=32.6683291770574, Blast_Score=227, Evalue=1e-59,
Organism=Homo sapiens, GI95147551, Length=397, Percent_Identity=30.4785894206549, Blast_Score=204, Evalue=9e-53,
Organism=Homo sapiens, GI169881279, Length=397, Percent_Identity=30.4785894206549, Blast_Score=204, Evalue=9e-53,
Organism=Homo sapiens, GI169881281, Length=397, Percent_Identity=27.455919395466, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI4507369, Length=342, Percent_Identity=23.9766081871345, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI149944424, Length=210, Percent_Identity=26.1904761904762, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1786816, Length=369, Percent_Identity=34.4173441734417, Blast_Score=249, Evalue=3e-67,
Organism=Escherichia coli, GI1788722, Length=362, Percent_Identity=30.6629834254144, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1788627, Length=233, Percent_Identity=25.3218884120172, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1790797, Length=384, Percent_Identity=25, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788332, Length=191, Percent_Identity=28.2722513089005, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787909, Length=353, Percent_Identity=22.9461756373938, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71994472, Length=419, Percent_Identity=29.3556085918854, Blast_Score=193, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI71994476, Length=419, Percent_Identity=29.3556085918854, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17567369, Length=418, Percent_Identity=29.4258373205742, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17567663, Length=306, Percent_Identity=23.5294117647059, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322401, Length=390, Percent_Identity=30.7692307692308, Blast_Score=202, Evalue=6e-53,
Organism=Drosophila melanogaster, GI28573069, Length=413, Percent_Identity=30.9927360774818, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24646114, Length=413, Percent_Identity=30.9927360774818, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI28573067, Length=413, Percent_Identity=30.9927360774818, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI28573065, Length=413, Percent_Identity=30.9927360774818, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI18859735, Length=350, Percent_Identity=26.2857142857143, Blast_Score=110, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 44137; Mature: 44137

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKELSNRSANFTDSVIRRMTRVANKYGAVNLSQGFPDFDPPKAITDRLARVAGEGPHQYA
CCCCCCCCCCHHHHHHHHHHHHHHHHCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCEEE
LTWGAKNFRDAVAKKYEHFSGVKIDPETEIVVTCGSTEAMMATMLSIINPGDKVVIFSPF
EEECCHHHHHHHHHHHHHCCCCEECCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEECCH
YENYGADTILSGAEPIYVPLVPPEFHFDKEKLEDAFRQGAKALILCNPSNPCGKVFTMEE
HHCCCCCCEECCCCCEEEECCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCEEEHHH
MQTIAELAKKYDAYVVTDEVYEHIVYAPNKHIYMQSLEGMRERTIVCNSLSKTYSITGWR
HHHHHHHHHHHCCEEEEHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCCCEEECCEE
LGYVIANPQIIDRVKKVHDFLTVGAAAPLMEAAVVGLEFGDGYYDELAAHYAHMKEVFVG
EEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHH
GLKKLGLKYTDPQGAYYVLVDVSEFGVKDDVKFCEWMAQFVGVAAVPGSSFFREDVHNLV
HHHHCCCEEECCCCCEEEEEEHHHCCCCCHHHHHHHHHHHHCEECCCCHHHHHHHHHHHH
RFHFAKQDDTLNEAIKRLATLKEKAINAKNVDWR
HHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKELSNRSANFTDSVIRRMTRVANKYGAVNLSQGFPDFDPPKAITDRLARVAGEGPHQYA
CCCCCCCCCCHHHHHHHHHHHHHHHHCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCEEE
LTWGAKNFRDAVAKKYEHFSGVKIDPETEIVVTCGSTEAMMATMLSIINPGDKVVIFSPF
EEECCHHHHHHHHHHHHHCCCCEECCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEECCH
YENYGADTILSGAEPIYVPLVPPEFHFDKEKLEDAFRQGAKALILCNPSNPCGKVFTMEE
HHCCCCCCEECCCCCEEEECCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCEEEHHH
MQTIAELAKKYDAYVVTDEVYEHIVYAPNKHIYMQSLEGMRERTIVCNSLSKTYSITGWR
HHHHHHHHHHHCCEEEEHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCCCEEECCEE
LGYVIANPQIIDRVKKVHDFLTVGAAAPLMEAAVVGLEFGDGYYDELAAHYAHMKEVFVG
EEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHH
GLKKLGLKYTDPQGAYYVLVDVSEFGVKDDVKFCEWMAQFVGVAAVPGSSFFREDVHNLV
HHHHCCCEEECCCCCEEEEEEHHHCCCCCHHHHHHHHHHHHCEECCCCHHHHHHHHHHHH
RFHFAKQDDTLNEAIKRLATLKEKAINAKNVDWR
HHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]