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The map label for this gene is argD [H]

Identifier: 238922322

GI number: 238922322

Start: 527307

End: 528671

Strand: Reverse

Name: argD [H]

Synonym: EUBELI_20558

Alternate gene names: 238922322

Gene position: 528671-527307 (Counterclockwise)

Preceding gene: 238922323

Following gene: 238922321

Centisome position: 84.35

GC content: 38.68

Gene sequence:

>1365_bases
ATGGAGGAAATTATGGCAACAGAATCAAGTATTATGGACTCTAACAGTTTTAAGGAAGAATATGCATCTATGTTAAGTCC
TAAAACAAGGGAAATGATTAGTAAGAGAGAAAAATACCTTGGAGGTGCTTACAGACTTTTTTATAGAAAGCCAATTAACA
TTGTCCGTGGAGAAGGAGATTATCTGTGGGATGATGAAGGTAACAAATATCTTGATATGTATAACAATGTAGCTGGTGTA
GGACATTGTAACCCTGCTGTTGTAAATGCAGTTACAGAACAGATGAAAACGCTTAATACACATACAAGATATCTTCATGA
AAAAATTCTTGATTACAGTGAAGAACTGCTTGCACTTATGCCTGATGAGATTAATAAGATAATGTATATGTGTACAGGTT
CAGAAGCTAATGACCTTGCACTTCGTGTGGCAGAAGCCTATACGGGTGGTACCGGTATAATTATCACACAGGAAGCCTAC
CACGGAACAAGTGCATTAACATCAGGCTGTTCACCTTCACTTGGAGCCGGTCAGCCATTACTTCCTAATGTAAGGCTTAT
AACAGCACCAGATTATTACCGTCATGGTGGAACACCAGAAGAATTCACAGCATGGTATGCGTCAGAGATGCAAAAGACTA
TAGATGAATTAAATGAGGCAGGATATAAGTTTTCTTGTTTCCTTGCTGATTCAATATTCTCATCAGATGGTATATATCCT
GACCCTGTAGGATTCTTAAAAGCAACAGTAGATGTTGTACATAAGAATGGCGGAGTATTTATAGCAGATGAGGTTCAGCC
GGGATTTGCAAGAACCGGACAGGCATTCTTTGGATTTGCAAGACACGGAATTGTCCCTGATATGATAACAATGGGTAAGC
CGATGGGTAACGGAATTCCAATCTCAGGACTAGCTGCAAAGGAGGATGTACTTGCAGCCTTCAGCGACAAGCTTCCTTAC
TTTAACACATTTGGTGGTAATCCTGTATCAATAGCTGCCGCTCAGGCTGTTCTTAAATATATTAAGGATGAAAATCTTCA
GGAACACTGTAAGAAAGCAGGTGCGGCACTTCTTAAGGCACTAAAAGAGGTACAGAAGCGTCATCCTGAATCAGTAGGTG
ATGTAAGAGGTGCAGGTTTGTTCTTAGGATTTGAATTTGTTAAGAATGATGGCAACAAGACACCTGATAAAGATATGGCG
TTGAATGTAATAGAGATGTTAAGAGATGAGCATATTCTTACATCAGTTATAGGTCATTACGGAAATATCTTAAAGCTTCG
TCCACCAATGGTATTTTCAGAGAATGATATTGACTGGTTTGCAACATCTCTGGATAAATGTATTACAAAGCTTGAAAATA
AATAA

Upstream 100 bases:

>100_bases
TTGCTATTATATATGTCAGACAGAATGAATCTGTATGACAGTGCAAAGGAGCACAGAATTTCTGAGAAATCAGAGGTTCT
GTGCTTTTTCTTTTTGCAGA

Downstream 100 bases:

>100_bases
ATTGAAAAAATCGGACACAGACATTAAACATCTGTGTCTTATTTTTTTGCTTACAACAAGAATTTTACATAAGATTTACA
GGGCAATTATTGTAAGTTTA

Product: hypothetical protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MEEIMATESSIMDSNSFKEEYASMLSPKTREMISKREKYLGGAYRLFYRKPINIVRGEGDYLWDDEGNKYLDMYNNVAGV
GHCNPAVVNAVTEQMKTLNTHTRYLHEKILDYSEELLALMPDEINKIMYMCTGSEANDLALRVAEAYTGGTGIIITQEAY
HGTSALTSGCSPSLGAGQPLLPNVRLITAPDYYRHGGTPEEFTAWYASEMQKTIDELNEAGYKFSCFLADSIFSSDGIYP
DPVGFLKATVDVVHKNGGVFIADEVQPGFARTGQAFFGFARHGIVPDMITMGKPMGNGIPISGLAAKEDVLAAFSDKLPY
FNTFGGNPVSIAAAQAVLKYIKDENLQEHCKKAGAALLKALKEVQKRHPESVGDVRGAGLFLGFEFVKNDGNKTPDKDMA
LNVIEMLRDEHILTSVIGHYGNILKLRPPMVFSENDIDWFATSLDKCITKLENK

Sequences:

>Translated_454_residues
MEEIMATESSIMDSNSFKEEYASMLSPKTREMISKREKYLGGAYRLFYRKPINIVRGEGDYLWDDEGNKYLDMYNNVAGV
GHCNPAVVNAVTEQMKTLNTHTRYLHEKILDYSEELLALMPDEINKIMYMCTGSEANDLALRVAEAYTGGTGIIITQEAY
HGTSALTSGCSPSLGAGQPLLPNVRLITAPDYYRHGGTPEEFTAWYASEMQKTIDELNEAGYKFSCFLADSIFSSDGIYP
DPVGFLKATVDVVHKNGGVFIADEVQPGFARTGQAFFGFARHGIVPDMITMGKPMGNGIPISGLAAKEDVLAAFSDKLPY
FNTFGGNPVSIAAAQAVLKYIKDENLQEHCKKAGAALLKALKEVQKRHPESVGDVRGAGLFLGFEFVKNDGNKTPDKDMA
LNVIEMLRDEHILTSVIGHYGNILKLRPPMVFSENDIDWFATSLDKCITKLENK
>Mature_454_residues
MEEIMATESSIMDSNSFKEEYASMLSPKTREMISKREKYLGGAYRLFYRKPINIVRGEGDYLWDDEGNKYLDMYNNVAGV
GHCNPAVVNAVTEQMKTLNTHTRYLHEKILDYSEELLALMPDEINKIMYMCTGSEANDLALRVAEAYTGGTGIIITQEAY
HGTSALTSGCSPSLGAGQPLLPNVRLITAPDYYRHGGTPEEFTAWYASEMQKTIDELNEAGYKFSCFLADSIFSSDGIYP
DPVGFLKATVDVVHKNGGVFIADEVQPGFARTGQAFFGFARHGIVPDMITMGKPMGNGIPISGLAAKEDVLAAFSDKLPY
FNTFGGNPVSIAAAQAVLKYIKDENLQEHCKKAGAALLKALKEVQKRHPESVGDVRGAGLFLGFEFVKNDGNKTPDKDMA
LNVIEMLRDEHILTSVIGHYGNILKLRPPMVFSENDIDWFATSLDKCITKLENK

Specific function: 4-aminobutyrate (GABA) degradation. [C]

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI37574042, Length=432, Percent_Identity=39.8148148148148, Blast_Score=327, Evalue=1e-89,
Organism=Homo sapiens, GI24119277, Length=439, Percent_Identity=38.496583143508, Blast_Score=316, Evalue=3e-86,
Organism=Homo sapiens, GI226442705, Length=432, Percent_Identity=38.6574074074074, Blast_Score=307, Evalue=2e-83,
Organism=Homo sapiens, GI226442709, Length=381, Percent_Identity=39.6325459317585, Blast_Score=284, Evalue=1e-76,
Organism=Homo sapiens, GI13994255, Length=474, Percent_Identity=30.379746835443, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI4557809, Length=446, Percent_Identity=27.1300448430493, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI188536080, Length=460, Percent_Identity=24.3478260869565, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI38679950, Length=460, Percent_Identity=24.3478260869565, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI38679946, Length=460, Percent_Identity=24.3478260869565, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI284507298, Length=215, Percent_Identity=30.2325581395349, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI1789016, Length=428, Percent_Identity=28.5046728971963, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI145693181, Length=447, Percent_Identity=25.0559284116331, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1788044, Length=414, Percent_Identity=24.8792270531401, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1787560, Length=396, Percent_Identity=29.040404040404, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1789759, Length=408, Percent_Identity=25.2450980392157, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1786349, Length=332, Percent_Identity=26.2048192771084, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1786991, Length=351, Percent_Identity=25.0712250712251, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71992977, Length=437, Percent_Identity=35.4691075514874, Blast_Score=292, Evalue=3e-79,
Organism=Caenorhabditis elegans, GI32564660, Length=431, Percent_Identity=33.6426914153132, Blast_Score=236, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI25144271, Length=437, Percent_Identity=26.3157894736842, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI71992985, Length=132, Percent_Identity=34.8484848484849, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI25144274, Length=227, Percent_Identity=28.6343612334802, Blast_Score=87, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323470, Length=443, Percent_Identity=25.5079006772009, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6324432, Length=364, Percent_Identity=26.3736263736264, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6321456, Length=213, Percent_Identity=28.6384976525822, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356575, Length=434, Percent_Identity=38.0184331797235, Blast_Score=300, Evalue=1e-81,
Organism=Drosophila melanogaster, GI161085790, Length=443, Percent_Identity=35.665914221219, Blast_Score=262, Evalue=4e-70,
Organism=Drosophila melanogaster, GI28574759, Length=447, Percent_Identity=35.7941834451902, Blast_Score=259, Evalue=2e-69,
Organism=Drosophila melanogaster, GI21357415, Length=447, Percent_Identity=25.2796420581655, Blast_Score=130, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 50120; Mature: 50120

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEIMATESSIMDSNSFKEEYASMLSPKTREMISKREKYLGGAYRLFYRKPINIVRGEGD
CCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHCCHHHEEEEECCCEEEECCCC
YLWDDEGNKYLDMYNNVAGVGHCNPAVVNAVTEQMKTLNTHTRYLHEKILDYSEELLALM
EEECCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PDEINKIMYMCTGSEANDLALRVAEAYTGGTGIIITQEAYHGTSALTSGCSPSLGAGQPL
HHHHCEEEEEEECCCCCHHHEEEHHHHCCCCEEEEECCCCCCHHHHHCCCCCCCCCCCCC
LPNVRLITAPDYYRHGGTPEEFTAWYASEMQKTIDELNEAGYKFSCFLADSIFSSDGIYP
CCCCEEEECCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHCCCCCCC
DPVGFLKATVDVVHKNGGVFIADEVQPGFARTGQAFFGFARHGIVPDMITMGKPMGNGIP
CCHHHHHHHHHHEECCCCEEEECCCCCCHHHCCHHHHHHHHHCCCHHHHHCCCCCCCCCC
ISGLAAKEDVLAAFSDKLPYFNTFGGNPVSIAAAQAVLKYIKDENLQEHCKKAGAALLKA
CCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LKEVQKRHPESVGDVRGAGLFLGFEFVKNDGNKTPDKDMALNVIEMLRDEHILTSVIGHY
HHHHHHHCCCHHHCCCCCHHEEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GNILKLRPPMVFSENDIDWFATSLDKCITKLENK
CCEEEECCCEEECCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEEIMATESSIMDSNSFKEEYASMLSPKTREMISKREKYLGGAYRLFYRKPINIVRGEGD
CCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHCCHHHEEEEECCCEEEECCCC
YLWDDEGNKYLDMYNNVAGVGHCNPAVVNAVTEQMKTLNTHTRYLHEKILDYSEELLALM
EEECCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PDEINKIMYMCTGSEANDLALRVAEAYTGGTGIIITQEAYHGTSALTSGCSPSLGAGQPL
HHHHCEEEEEEECCCCCHHHEEEHHHHCCCCEEEEECCCCCCHHHHHCCCCCCCCCCCCC
LPNVRLITAPDYYRHGGTPEEFTAWYASEMQKTIDELNEAGYKFSCFLADSIFSSDGIYP
CCCCEEEECCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHCCCCCCC
DPVGFLKATVDVVHKNGGVFIADEVQPGFARTGQAFFGFARHGIVPDMITMGKPMGNGIP
CCHHHHHHHHHHEECCCCEEEECCCCCCHHHCCHHHHHHHHHCCCHHHHHCCCCCCCCCC
ISGLAAKEDVLAAFSDKLPYFNTFGGNPVSIAAAQAVLKYIKDENLQEHCKKAGAALLKA
CCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LKEVQKRHPESVGDVRGAGLFLGFEFVKNDGNKTPDKDMALNVIEMLRDEHILTSVIGHY
HHHHHHHCCCHHHCCCCCHHEEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GNILKLRPPMVFSENDIDWFATSLDKCITKLENK
CCEEEECCCEEECCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]