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The map label for this gene is slyD [H]

Identifier: 238921454

GI number: 238921454

Start: 3491320

End: 3491931

Strand: Reverse

Name: slyD [H]

Synonym: NT01EI_3606

Alternate gene names: 238921454

Gene position: 3491931-3491320 (Counterclockwise)

Preceding gene: 238921455

Following gene: 238921452

Centisome position: 91.6

GC content: 57.03

Gene sequence:

>612_bases
ATGAAAGTAGCTAAAGACCTGGTGGTCAGTCTGGCCTATCAGGTGCGTACGGAAGACGGAGTATTGGTTGATGAGTCTCC
GGTGTCAGCACCGCTGGACTACCTGCACGGCCATGGCTCTCTGATTGCCGGCCTGGAAAAAGCGCTGGAAGGCCACGTCG
TTGGCGATCGTTTCGACGTGCATGTTCCGGCTAATGATGCCTACGGCCAGTATGATGACAACCTGGTACAGCGTGTACCG
AAGGATGTCTTCATGGGGGTTGACGAGCTGCAGGTTGGCATGCGTTTCCTGGCGGAAACCGATCAGGGCCCGGTACCGGT
CGAAATTACCGAAGTGGGTGATGACTATGTTGTGGTTGACGGCAACCACATGCTGGCTGGCCAGAATCTGAACTTCAATG
TGGAAGTGGTTGCCCTGCGTGAAGCGACTGCTGAAGAGCTGGAGCATGGTCATGTTCACGGTGCTCACGATCACCACGGC
GAATGTTGCGGTGGGCATGGTAACGGCGAAGGTGAGTGCTGTGGCGGCCATGACCACGATCATGAGCACGCAGAAGGTGA
CACCTGCTGCGGCGGTCAGGGTAAAGGTCACGGCGGCTGTGGCTGCCATTGA

Upstream 100 bases:

>100_bases
AAGTGGGTGGGCGGTGCAGCTTTTTTTATTCTGAACCGTACAGTGGCGCGAAATTCCGCTACAATCCGCTCGGATTCAGT
TTCAAACGCTAGGAGATATC

Downstream 100 bases:

>100_bases
TTGCCCCTGTAAAAAAGCGGTCAGATGACCGCTTTTTTATTTTCTGTACCGCGCCGTCTCAGTAGTGGGGGGGGGGCGTC
TCTTCCGACGGATGCGCCAT

Product: fkbp-type peptidyl-prolyl cis-trans isomerase slyd (whp)

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MKVAKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLIAGLEKALEGHVVGDRFDVHVPANDAYGQYDDNLVQRVP
KDVFMGVDELQVGMRFLAETDQGPVPVEITEVGDDYVVVDGNHMLAGQNLNFNVEVVALREATAEELEHGHVHGAHDHHG
ECCGGHGNGEGECCGGHDHDHEHAEGDTCCGGQGKGHGGCGCH

Sequences:

>Translated_203_residues
MKVAKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLIAGLEKALEGHVVGDRFDVHVPANDAYGQYDDNLVQRVP
KDVFMGVDELQVGMRFLAETDQGPVPVEITEVGDDYVVVDGNHMLAGQNLNFNVEVVALREATAEELEHGHVHGAHDHHG
ECCGGHGNGEGECCGGHDHDHEHAEGDTCCGGQGKGHGGCGCH
>Mature_203_residues
MKVAKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLIAGLEKALEGHVVGDRFDVHVPANDAYGQYDDNLVQRVP
KDVFMGVDELQVGMRFLAETDQGPVPVEITEVGDDYVVVDGNHMLAGQNLNFNVEVVALREATAEELEHGHVHGAHDHHG
ECCGGHGNGEGECCGGHDHDHEHAEGDTCCGGQGKGHGGCGCH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=147, Percent_Identity=91.156462585034, Blast_Score=266, Evalue=9e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 21571; Mature: 21571

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLIAGLEKALEGHVVGDRFDV
CCHHHHHHHHHHHEEECCCCEEEECCCCCCCHHHHCCCCHHHHHHHHHHCCCEECCEEEE
HVPANDAYGQYDDNLVQRVPKDVFMGVDELQVGMRFLAETDQGPVPVEITEVGDDYVVVD
EECCCCCCCCCCHHHHHHCCHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEC
GNHMLAGQNLNFNVEVVALREATAEELEHGHVHGAHDHHGECCGGHGNGEGECCGGHDHD
CCEEEECCCCCCEEEEEEECHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCEECCCCCC
HEHAEGDTCCGGQGKGHGGCGCH
CCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKVAKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLIAGLEKALEGHVVGDRFDV
CCHHHHHHHHHHHEEECCCCEEEECCCCCCCHHHHCCCCHHHHHHHHHHCCCEECCEEEE
HVPANDAYGQYDDNLVQRVPKDVFMGVDELQVGMRFLAETDQGPVPVEITEVGDDYVVVD
EECCCCCCCCCCHHHHHHCCHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEC
GNHMLAGQNLNFNVEVVALREATAEELEHGHVHGAHDHHGECCGGHGNGEGECCGGHDHD
CCEEEECCCCCCEEEEEEECHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCEECCCCCC
HEHAEGDTCCGGQGKGHGGCGCH
CCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]